Mycobacterium marinum M: MMAR_3334
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Entry
MMAR_3334 CDS
T00694
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component AceE
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mmi
Mycobacterium marinum M
Pathway
mmi00010
Glycolysis / Gluconeogenesis
mmi00020
Citrate cycle (TCA cycle)
mmi00620
Pyruvate metabolism
mmi00785
Lipoic acid metabolism
mmi01100
Metabolic pathways
mmi01110
Biosynthesis of secondary metabolites
mmi01120
Microbial metabolism in diverse environments
mmi01200
Carbon metabolism
mmi01210
2-Oxocarboxylic acid metabolism
Module
mmi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MMAR_3334 (aceE)
00020 Citrate cycle (TCA cycle)
MMAR_3334 (aceE)
00620 Pyruvate metabolism
MMAR_3334 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MMAR_3334 (aceE)
Enzymes [BR:
mmi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MMAR_3334 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ACC41760
UniProt:
B2HHR2
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All DBs
Position
4113674..4116463
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AA seq
929 aa
AA seq
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MTTEFVRHDLAKTSSSASEPDRVRVIREGVASYLPDIDPEETSEWLESFDALLEHSGPAR
ARYLMLRLLERAGEQRVAIPSLTSTDYVNTIPTELEPWFPGDEDVERRYRTWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHMGALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVANMSDQEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALADLKRFRDSMRIPVSDAQLDEDPYLPPYYHPGSDAP
EIRYMLDRRRTLGGFLPERPTKAKTLTLPGPDAYKVLKKGSGQQEVATTMALVRTFKELL
RDKNIGNRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESHVGQILH
EGINEAGSVGSFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAYELAYIIENGLSRMFGENPENIY
FYITVYNEPYVQPAEPENFDPEGVLRGMYRYRAATKQCAHKAQLLASGVSMPDALKAAQM
LADEWDVATDVWSVTSWSELNRDGVSVERHRLRHPGEPAGVAYVTTALEGTSGPVVAVSD
WMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARDGEID
ESVAVTAARQYRIDDVQAAPKQTSDSGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgtccgccacgatcttgccaaaacctcaagcagcgcaagcgaaccc
gaccgcgttcgggtcattcgcgaaggcgtggcgtcctacctgcccgatattgaccccgag
gaaacttcggaatggctggagtcattcgacgcactcttggagcactccggaccggcgcgg
gcgcgctatttgatgctgcgactgctcgagcgggcgggcgaacaacgcgtcgccatcccg
tcattgacctcaacggattacgtcaacaccatccccaccgagttggagccatggtttccc
ggcgatgaggatgtcgagcgccgctaccggacctggatcaggtggaacgcggcaatcatg
gtgcaccgcgcacaacgcccgggcgtcggcgtcggtggccacatctcgacctacgcttcg
tccgcggccctctacgaggtcggcttcaaccacttcttccgcggcaaatcgcatcccggc
ggcggagaccaggtgttcatccagggccatgcctcccccggcatttatgcccgcgcgttc
ctggagggacgactcagcgcggatcagcttgacggcttccggcaggagcacagccacccc
ggtggcgggttgccttcctacccgcacccacggctgatgcccgacttctgggaattcccg
accgtgtcgatgggcctgggtccgctcaacgccatctaccaggcgcggttcaaccactac
ctgcacgaccgcggcatcaaggacacctccgatcagcacgtgtggtgtttcctgggcgac
ggcgagatggacgagccggaaagccgcggactggcccacatgggcgcgctggaaggcctg
gacaacctgaccttcgtgatcaactgcaatctgcaacgcctggacggcccggtccgcggc
aacggcaagatcatccaggaactggagtccttcttccgcggcgcgggctggaacgtgatc
aaggtggtctggggccgcgagtgggatgcgctgctgcacgccgaccgcgacggcgcgctg
gtgaacctgatgaacagcacccccgacggcgactaccagacctacaaggccaatgacggc
gcctacgtgcgcgaccacttctttggccgcgacccccggaccaaggccctggtggccaac
atgagcgaccaggagatctggaatctcaagcgtggcggccacgactaccgcaaggtctat
gccgcctaccgcgccgccgtcgaccacaagggtcagccgacggtgatcctggccaagacc
atcaagggctattcgcttggcgcgcacttccagggccgcaatgccacgcaccagatgaaa
aagcttgccctcgccgacctcaagcggttccgggattcgatgcgcatcccggtcagcgat
gcccagctcgacgaggacccctacctgccgccctactaccacccgggctcggacgccccg
gagatccggtacatgcttgaccggcgccgcaccctgggcgggttcctgcccgagcgcccg
accaaggccaagaccctgaccctgcccggccccgacgcctacaaggtgctcaagaagggg
tccggacaacaagaggtcgccaccaccatggccctggtccgtaccttcaaagaactgttg
cgcgacaagaacattgggaatcggattgtcccgatcattcccgacgaggcccgcaccttc
gggatggactcctggttcccgtcgctcaagatctacaaccgcaatgggcagctgtacacc
gccgtcgacgcggaactgatgctggcgtataaggaaagccacgtcggccagatcctgcac
gagggcatcaacgaagccgggtcggtgggctccttcaccgcggccggcacctcgtatgcg
acccacaacgagccgatgatcccgatctacatcttctattcgatgttcgggttccagcgc
accggtgacagcttttgggccgccgccgaccagatggcacgcgggttcgtgctgggtgcg
accgctggacgcaccacgctgaccggtgagggtctgcaacatgccgatggccactcgctg
ctgctggccgcgaccaatccggcggtggtctcctacgacccggcgtttgcctacgagctc
gcctacatcatcgaaaatggcctgtctcggatgttcggggagaacccggagaacatctac
ttctacatcaccgtttacaacgagccgtatgtgcagccggccgagccggagaacttcgat
cccgagggcgtgctgcgcggcatgtaccgctaccgcgcggcgaccaaacagtgcgcgcac
aaggctcagctgctggcctccggggtgtcgatgcccgacgcgctgaaggcggcgcagatg
ctggccgacgagtgggacgtcgcgactgacgtgtggtcggtgaccagttggagcgagctg
aaccgcgacggggtgtccgtcgaacgtcaccggctgcgtcaccccggtgaacccgccggt
gtcgcctacgtgacgacggcgctggaaggcaccagcggcccggtggtcgcggtatcggac
tggatgcgcgcggtgcccgagcagatccggccctgggtgcccgggacctacgtcaccctc
ggcaccgacgggttcggtttctccgacacccggcccgccgcccgccgctacttcaacacc
gatgccgagtcacaggtggtcgcggtgctcgaggcgctggcccgcgacggtgagatcgat
gagtcggtggccgtcaccgccgcccgtcagtaccggatcgatgatgtgcaggccgcgccg
aagcagacctcggattccggcgtcgcataa
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