Mycobacterium marinum M: MMAR_4194
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Entry
MMAR_4194 CDS
T00694
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase Kgd
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mmi
Mycobacterium marinum M
Pathway
mmi00020
Citrate cycle (TCA cycle)
mmi00630
Glyoxylate and dicarboxylate metabolism
mmi00785
Lipoic acid metabolism
mmi01100
Metabolic pathways
mmi01110
Biosynthesis of secondary metabolites
mmi01120
Microbial metabolism in diverse environments
mmi01200
Carbon metabolism
mmi01210
2-Oxocarboxylic acid metabolism
Module
mmi_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mmi_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MMAR_4194 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MMAR_4194 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MMAR_4194 (kgd)
Enzymes [BR:
mmi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MMAR_4194 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MMAR_4194 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MMAR_4194 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MMAR_4194 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ACC42602
UniProt:
B2HRH1
LinkDB
All DBs
Position
5166708..5170463
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AA seq
1251 aa
AA seq
DB search
MRRTAAVANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPESTQEATEPAVE
KPAVAPAKPAAAPAKPAPAPAPAKPAAGPPAAGNGSPAAAPSAKPAAAPAKAPAPPPAEG
DEMQVLRGAAAAVVKNMSASLDVPTATSVRAVPAKLLIDNRIVINNQLKRNRGGKISFTH
LLGYALVQAVKKFPNMNRHYLDVDGKPNAVTPAHTNLGLAIDLQGKDGKRALVVAGIKRC
ETMRFAQFVTAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMAGQGAIIG
VGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHQMLLADEFW
DEIFRELSIPYLPVRWRPDNPDSIVDKNARIIELIAAYRNRGHLMADIDPLRLDKTRFRS
HPDLDVCTHGLTLWDLDRSFKVGGCFAGPQNMKLRDVLSILRDAYCRHVGVEYTHILEPE
QQQWLQQRVEAKHVKPTVAQQKYVLSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMM
DAAIDQCAEYGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKY
HLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLEHGETDTENQRAFS
VVPMMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSTEYCT
DVAKTIGAPIFHVNGDDPEACVWVARLAVDFRQRFNKDVIIDMLCYRRRGHNEGDDPSMT
NPRMYDVVDTKRGVRKSYTEALIGRGDISIKEAEDALRDYQGQLEQVFNEVRELEKHGAQ
PSESVESDQMIPAGLATAVDKSLLARIGDAFLAVPDGFTTHPRVQPVLEKRREMAYEGKI
DWAFAELLALGSLVAEGKLVRFSGQDTRRGTFSQRHSVIIDRHTREEFTPLQLLTTNKDG
SPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGE
AKWGQLSNVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHA
LDGIQRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGVGDRNLVNRILLTS
GKIYYEMVARKAKDKREDVAIVRVEQLAPLPRRRLRETLDRYPNAKEFFWVQEEPANQGA
WPRFGLELPELLPEKLSGVKRISRRAMSAPSSGSSKVHAVEQQEILDTAFG
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
ttgaggcgaacagcggccgtggccaacataagttcaccattcggacaaaacgaatggctg
gtcgaggagatgtaccgcaagttccgcgacgacccttcgtcggtcgatccaagctggcac
gagttcctggttgactacaaccccgagtcgactcaggaagcgacggaacccgccgtggaa
aagcccgccgtagccccggcgaagcccgccgccgctccggcgaagcccgcgcccgcaccg
gcgcccgccaaacccgccgccggcccgcccgcggcgggtaacggctcgcccgccgcggca
cccagcgccaagccagccgcggctccagcaaaggctcccgcgccgccacccgccgagggc
gacgagatgcaggtgctgcgcggcgccgccgcggcggtggtgaagaacatgtccgcatcg
ctggacgtgccgaccgcaaccagcgtccgcgcggtgccggccaaactgttgattgacaac
cggatcgtcatcaacaaccagctcaagcgcaatcgcggcggcaagatctcgttcacgcac
ctgctgggctacgccctggtgcaggcggtcaaaaagttccccaacatgaaccggcattac
ctcgatgtcgacggcaagccaaacgcggtcacgccggcgcacaccaatctgggcctggct
atcgacctgcagggcaaagacggcaaacgcgcgttggtggtggccgggatcaagcggtgc
gagacgatgcggttcgcgcagttcgtcaccgcctacgaggacatcgtgcgccgggcccgc
gacggcaaactgaccgccgaagacttttccggcgtgacgatttcgctgaccaaccccgga
accatcggcaccgtgcattcggtgccgcggctgatggccggtcagggcgccatcatcggt
gtcggcgccatggaatacccggccgagttccaaggggccagcgaggagcgcatcgccgaa
ctcggtatcggcaagctgatcactttgacctcgacgtatgaccaccgcatcatccagggt
gcggaatccggcgacttcttgcgcaccatccaccagatgctgctcgccgacgagttctgg
gacgagatcttccgcgagttgagcattccctacttgccggtgcgctggcgccccgacaac
ccggactcgatcgtcgacaagaacgcccggatcatcgagctgattgccgcctaccgcaac
cgcggtcacctgatggccgacatcgatccgcttcgcctggacaagactcgcttccgcagt
caccccgacctggacgtgtgcacccacgggctgacgctgtgggatctggaccgatcgttc
aaggtcggcggctgctttgccggaccgcagaacatgaagctgcgcgacgtgttgtcgatc
ctgcgcgacgcctactgccgtcatgtcggcgtcgagtacacacacatcctcgaacccgaa
cagcaacagtggctgcagcagcgcgtcgaggccaagcatgtcaaaccgactgtggcccaa
cagaaatacgtgctgagcaagctgaacgccgccgaggctttcgaaacgttcctgcagacc
aagtacgtgggccagaagcgtttctcactcgagggcgccgagagtgtcatcccgatgatg
gacgccgcgatcgaccagtgcgccgagtacggcctggacgaagtggtcatcggcatgccg
caccgcggccggctcaacgtgctggccaacatcgtcggcaagccgtactcgcagattttc
agcgagttcgagggcaatctgaacccgtcgcaggcgcacggctccggcgatgtgaagtat
cacctcggtgccactggcgtctatctacagatgttcggagacaacgacattcaggtgtcg
ttgaccgccaacccgtcacacctggaagccgtggacccggtgctcgagggtctggtccgg
gccaagcaggacctgctcgaacatggcgagaccgacaccgagaatcaacgcgctttctcg
gtggtgccgatgatgctgcacggcgacgccgccttcgccggacagggcgtggtcgccgag
acactgaacctggcgaatctgcctggttaccgtgttggcggcaccatccacatcatcgtc
aacaaccagatcggcttcaccaccgcgcccgagtactcgcggtccaccgaatattgcacc
gacgtcgccaagacaatcggggcaccgatcttccacgtcaacggcgatgaccccgaggca
tgcgtgtgggtggcccggctggcggtggacttccggcagcggttcaacaaagacgtcatc
atcgacatgctgtgctaccgccggcgcggacacaacgagggcgatgacccgtcgatgacc
aacccgcggatgtacgacgtcgtcgacaccaaacgcggggtccgcaagagctacaccgaa
gccctgatcggccgtggcgacatctcgatcaaggaagccgaggacgccctgcgcgactac
cagggccagctggagcaggtgttcaacgaggtccgcgagctcgagaagcacggtgcccaa
cccagcgaatccgtcgaatccgaccagatgattccggcggggctggccaccgcggtggac
aaatcgctgctggcccgcatcggcgacgcgttcctggccgtgccggacgggttcactacc
catccacgggtccagccggtgctggaaaagcgccgggaaatggcctacgaaggcaagatc
gactgggccttcgccgaattgctggcgcttggttcgctggtcgccgaaggcaagctggtg
cggttctccgggcaggacacccggcgcggcaccttctcgcagcgtcattcggtgatcatc
gaccgccacacccgcgaggaattcacccccctgcagctgctgaccacgaacaaggacggc
agcccgaccggcggcaagttcctggtctatgactcaccgctgtcggagtacgcggcggtg
ggcttcgagtacggctacacggtgggcaaccccgacgccgtcgtgctgtgggaagcgcag
ttcggcgacttcgtcaatggcgcgcaatcgatcatcgacgagttcatcagctccggcgag
gccaagtggggccagctgtccaacgtggtgctgctgctaccacacgggcacgaggggcaa
ggccccgaccacacctccgggcgcatcgaacgcttcctgcagttgtgggcggagggctcg
atgaccatcgcgatgccgtcgactccgtcgaactacttccacctgctgcgcaggcatgct
ctcgacgggattcagcgcccgctgatcgtcttcacgcccaagtcgatgctgcgcaacaag
gccgcggtcagtgacatcaaggacttcaccgagatcaagttccgctcggtgctcgaggaa
cccacctacgaggacggcgtcggcgaccgcaacttggtgaaccggatcctgctgaccagc
ggcaagatctactacgagatggtggcccgcaaggccaaggacaagcgtgaggacgtggcg
atcgtgcgggtcgagcaactcgctccactgcccaggcgccggctgcgcgaaacgctggac
cgctaccccaacgccaaggagttcttctgggtgcaggaggagccggccaaccagggggcg
tggccacggttcggcctggagctgcccgagctgctgcccgaaaagctgagcggcgtcaag
cgcatttcccgccgggccatgtcggcaccgtcatcaggttcgtcgaaggtgcacgccgtc
gaacagcaggagatcctggacaccgcgttcggctga
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