KEGG   Mycobacterium marinum M: MMAR_4825
Entry
MMAR_4825         CDS       T00694                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase, MetH
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mmi  Mycobacterium marinum M
Pathway
mmi00270  Cysteine and methionine metabolism
mmi00450  Selenocompound metabolism
mmi00670  One carbon pool by folate
mmi01100  Metabolic pathways
mmi01110  Biosynthesis of secondary metabolites
mmi01230  Biosynthesis of amino acids
mmi04980  Cobalamin transport and metabolism
mmi04981  Folate transport and metabolism
Module
mmi_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mmi00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    MMAR_4825 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    MMAR_4825 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    MMAR_4825 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    MMAR_4825 (metH)
   04980 Cobalamin transport and metabolism
    MMAR_4825 (metH)
Enzymes [BR:mmi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     MMAR_4825 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: ACC43230
UniProt: B2HGB8
LinkDB
Position
5879550..5883284
AA seq 1244 aa
MSAFEPNIRPDCTDALTAALGQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGN
NDLLSLTQPQIIEGIHREYLQAGADILETNTFNANAVSLSDYDMAELAYELNYAGAALAR
AAADEFSTPEKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVDGG
ADIIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGTITDASGRTLSGQVTEAFWNA
IRHAKPIAVGLNCALGAPEMRPYIAEMARIADTFVSCYPNAGLPNAFGEYDETPEHQAGY
IAEFADAGLVNLVGGCCGTAPPHIAEIAKVVEGKAPRELPEIPVATRLSGLEPLNISDDS
LFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMD
RFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISMKEGEEKFVREARLCR
KYGAAVVVMAFDEKGQADNLERRKEICGRAYRILTEEVGFPAEDIIFDPNCFALATGIEE
HATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDM
GIVNAGALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFNTKGKSEDPAAAEWRS
LPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEVIEGPLMDGMNVVGDLFGAGK
MFLPQVVKSARVMKKAVAYLLPFIEAEKAQSGSTEQDKTNGIIIMATVKGDVHDIGKNIV
GVVLQCNNYTVVDLGVMVPAEKILAAAREYDADIIGLSGLITPSLDEMVNFAAAMEREGM
QIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPGLLEATAAD
YAALRERHSQKNERPMLTLEKARANRTPIDWDGYTPPLPAQGLGVREFHDYDLAELREYI
DWQPFFNAWEMKGRFPDILNNPATGEAARKLYNDAQEMLDTLIREKWLTANGVIGFFPAN
AVGDDIEVYTDETRAEVLTTLHNLRQQGEHRAGIPNRSLGDFIAPKDTGLADYVGAFAVT
AGLGSQTKIVEFKEALDDYSAILLESIADRLAEAFAERMHQRVREEFWGYQPDEQLDNEA
LIGERYVGIRPAPGYPACPEHTEKTTLFELMDVTKRTGIELTESMAMWPGAAVSGWYFSH
PQSQYFVVGRMAQDQVADYAKRKGWTLPEAERWLGPNLGYNPED
NT seq 3735 nt   +upstreamnt  +downstreamnt
gtgagcgcctttgagccgaatatccgccctgactgcaccgacgcactgacggccgccctc
ggccagcggatcatggtgatcgacggggcgatgggcacggcgatccagcgggaccgcccg
gatgaggccggctatcgaggcgagcggttcaaggactggccgagcgatctggtgggcaac
aacgacctgctcagcctgacgcagccgcagatcatcgagggaatccaccgcgagtacctg
caggcgggcgccgacattctggagaccaacacgttcaacgcgaacgcggtctcgctctcc
gactacgacatggccgagctggcctacgaactcaactacgccggcgcggccctggcgcgg
gcggccgccgacgagttcagcaccccggagaagccccgttacgtggccggggcgctgggg
ccgacgacgcggaccgcatcgatctcgccggacgtcaacgaccccggagcccgcaacgtc
tcctacgaccaactggtcgccgcctacctggaagccgccaacggcctggtcgacggcggc
gccgacatcatcatcatcgagacaatcttcgactccctgaacgccaaggcggcggtgttc
gccgtcgaaacgctgttcgaggaccgcggacgccgctggccggtgatcatctcgggcacc
atcaccgacgcttccgggcgaacgctgtccggtcaggtgaccgaagcattctggaacgcg
atcaggcacgcgaagccgatcgcggtgggcctcaactgcgccctgggtgcgccggagatg
cggccctacatcgccgagatggcccggatcgcggatacctttgtctcctgctacccgaac
gccggtctgcccaatgccttcggcgagtacgacgagacccccgagcatcaggccggctac
atcgccgagtttgccgacgccggcctggtcaacctggtcggtgggtgctgcgggacggcg
ccgccgcacatcgccgagatcgccaaggtcgtcgagggcaaggcaccccgcgagctgccg
gagatcccggtggccacccggctctcgggcctggagccactgaacatcagcgacgactcc
ctgttcgtgaacatcggcgagcgcaccaacatcaccggatccgcccggttccgcaacctg
atcaaggccgaggactacgacaccgccctgtcggtcgccctgcagcaggtcgaggtcggt
gcgcaggtcatcgacatcaacatggacgagggcatgatcgacggcgtcgccgcgatggat
cggttcaccaagctgatcgcggccgagccggacatcagccgggtcccggtgatgatcgac
tcctccaagtgggaggtcatcgaggcgggcctgaagaacgtgcagggtaagccgatcgtc
aactcgatctcgatgaaggagggcgaggagaagttcgtccgcgaggcgcggctgtgccgc
aagtacggcgccgccgtggtcgtgatggccttcgacgaaaagggccaggccgacaacctg
gagcggcgcaaggagatctgcgggcgcgcctaccggatcctgaccgaagaggtcggcttc
ccggccgaggacatcatcttcgacccgaactgcttcgcgctcgcgaccggcatcgaggag
cacgcgacctacggcatcgacttcatcgaggcctgcgcctggatcaaggagaaccttccc
ggggtacacatctccggcggtatctcgaacgtgtcgttctcgttcaggggaaacaacccc
gttcgcgaggcgatccacgcggtgttcctgttccacgccatcaaggccggcctggacatg
ggcatcgtcaacgccggcgcgctggtgccctacgactcgatcgaccccgagctgcgggaa
cgcatcgaggacgtcgtcctgaaccgtcgcgaggacgcggccgaacggctgttggagatc
gccgaacggttcaacaccaagggcaagtccgaagacccggccgcggccgagtggcgcagc
cttcccgtccgcgagcggatcacgcacgccctggtcaagggcatcgacgcgcacgtcgac
gccgataccgaggaactgcgggccgagatcgccgccgcgggtggccgcccgatcgaggtg
atcgagggtccgctgatggacggcatgaacgtggtcggcgacctgttcggcgcgggcaag
atgttcctgccccaagtggtgaagtcggcccgggtgatgaagaaggcggtggcctacctg
ctgccgttcatcgaggcggagaaggcgcagtccggctccacggagcaggacaagaccaac
ggcatcatcatcatggcgaccgtcaagggcgacgtccacgacatcggcaagaacatcgtc
ggggtggtgctgcagtgcaacaactacaccgtggtcgacctcggagtgatggtgcccgcc
gagaagatcctggccgcggcccgggagtacgacgccgacatcatcgggctgtccggcctg
atcaccccgtccctggacgagatggtcaacttcgccgccgcgatggaacgcgagggaatg
cagatcccgctgctgatcggcggcgcgaccacctcacgcgcgcacacggcggtgaaggtg
gcgccgcgtcgcagcggcccggtggtgtgggtcaaggacgcttcccgctcggtgcccgtc
gccgccgcgttgctcgacgacaagcagcgcccgggcctgctggaggccaccgcggccgac
tacgcggccctgcgcgagcggcactcgcagaagaacgagcggccgatgctgacgctggag
aaggcccgcgccaaccggacgccgatcgactgggacggctacacgccgccgctgcccgcg
caaggtctcggggtgcgcgagtttcatgactacgacctggcggagttgcgcgagtacatc
gactggcagccgttcttcaacgcctgggagatgaagggccgattccccgacatcctcaac
aatccggccaccggcgaggccgcccgcaagctgtacaacgacgctcaagaaatgctcgac
accctgatccgggagaagtggctcaccgccaacggggtgatcgggttcttcccggcaaac
gcggtcggtgacgacatcgaggtgtacaccgacgagacccgtgccgaggtgctgaccacg
ttgcacaacctgcgccagcagggtgagcaccgggccggcattccgaaccggtcgctgggc
gacttcatcgcgcccaaggacaccggtcttgccgactacgtcggcgccttcgccgtcacc
gcggggctgggcagccagaccaagatcgtggagttcaaggaggcgctcgacgactacagc
gcgattctgctggagtcgatcgccgaccggctggccgaggcgtttgccgagcggatgcac
cagcgggtccgcgaggagttctggggataccagcccgacgagcagctggacaacgaggcg
ctcatcggtgagaggtatgtcggcatccgcccggcgccgggctacccggcctgcccggag
cacaccgagaagacgacgctgttcgagttgatggacgtgaccaagcggaccggcatcgag
ctgaccgagtcgatggcgatgtggcccggtgccgccgtcagcggctggtatttctcgcac
ccgcagtcgcagtacttcgtggtcggccggatggcccaggaccaggtcgccgactacgcc
aagcgcaagggctggaccctgccggaggccgagcgctggctgggccccaacctcggctac
aacccggaggactga

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