Mycobacterium tuberculosis variant microti: RN08_2488
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Entry
RN08_2488 CDS
T04291
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mmic
Mycobacterium tuberculosis variant microti
Pathway
mmic00010
Glycolysis / Gluconeogenesis
mmic00020
Citrate cycle (TCA cycle)
mmic00620
Pyruvate metabolism
mmic00785
Lipoic acid metabolism
mmic01100
Metabolic pathways
mmic01110
Biosynthesis of secondary metabolites
mmic01120
Microbial metabolism in diverse environments
mmic01200
Carbon metabolism
mmic01210
2-Oxocarboxylic acid metabolism
Module
mmic_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
RN08_2488
00020 Citrate cycle (TCA cycle)
RN08_2488
00620 Pyruvate metabolism
RN08_2488
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RN08_2488
Enzymes [BR:
mmic01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
RN08_2488
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GFIT
Motif
Pfam:
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AMC59915
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Position
2508302..2509819
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AA seq
505 aa
AA seq
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MTTDFARHDLAQNSNSASEPDRVRVIREGVASYLPDIDPEETSEWLESFDTLLQRCGPSR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLTAEQLDGFRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
GYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAP
EIRYMLDRRRALGALFPSAGPSPKR
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgatttcgcccgccacgatctggcccaaaactcaaacagcgcaagcgaaccc
gaccgagttcgggtgatccgcgagggtgtggcgtcgtatttgcccgacattgatcccgag
gagacctcggagtggctggagtcctttgacacgctgctgcaacgctgcggcccgtcgcgg
gcccgctacctgatgttgcggctgctagagcgggccggcgagcagcgggtggccatcccg
gcattgacgtctaccgactatgtcaacaccatcccgaccgagctggagccgtggttcccc
ggcgacgaagacgtcgaacgtcgttatcgagcgtggatcagatggaatgcggccatcatg
gtgcaccgtgcgcaacgaccgggtgtgggcgtgggtggccatatctcgacctacgcgtcg
tccgcggcgctctatgaggtcggtttcaaccacttcttccgcggcaagtcgcacccgggc
ggcggcgatcaggtgttcatccagggccacgcttccccgggaatctacgcgcgcgccttc
ctcgaagggcggttgaccgccgagcaactcgacggattccgccaggaacacagccatgtc
ggcggcgggttgccgtcctatccgcacccgcggctcatgcccgacttctgggaattcccc
accgtgtcgatgggtttgggcccgctcaacgccatctaccaggcacggttcaaccactat
ctgcatgaccgcggtatcaaagacacctccgatcaacacgtgtggtgttttttgggcgac
ggcgagatggacgaacccgagagccgtgggctggcccacgtcggcgcgctggaaggcttg
gacaacttgaccttcgtgatcaactgcaatctgcagcgactcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccgcggtgccggctggaacgtcatc
aaggtggtgtggggccgcgaatgggatgccctgctgcacgccgaccgcgacggtgcgctg
gtgaatttaatgaatacaacacccgatggcgattaccagacctataaggccaacgacggc
ggctacgtgcgtgaccacttcttcggccgcgacccacgcaccaaggcgctggtggagaac
atgagcgaccaggatatctggaacctcaaacggggcggccacgattaccgcaaggtttac
gccgcctaccgcgccgccgtcgaccacaagggacagccgacggtgatcctggccaagacc
atcaaaggctacgcgctgggcaagcatttcgaaggacgcaatgccacccaccagatgaaa
aaactgaccctggaagaccttaaggagtttcgtgacacgcagcggattccggtcagcgac
gcccagcttgaagagaatccgtacctgccgccctactaccaccccggcctcaacgccccg
gagattcgttacatgctcgaccggcgccgggccctcggggctttgttcccgagcgcagga
ccaagtccaaagcgctga
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