Mycobacterium sp. MOTT36Y: W7S_06310
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Entry
W7S_06310 CDS
T02113
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mmm
Mycobacterium sp. MOTT36Y
Pathway
mmm00020
Citrate cycle (TCA cycle)
mmm00630
Glyoxylate and dicarboxylate metabolism
mmm00785
Lipoic acid metabolism
mmm01100
Metabolic pathways
mmm01110
Biosynthesis of secondary metabolites
mmm01120
Microbial metabolism in diverse environments
mmm01200
Carbon metabolism
mmm01210
2-Oxocarboxylic acid metabolism
Module
mmm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mmm_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mmm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
W7S_06310 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
W7S_06310 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
W7S_06310 (kgd)
Enzymes [BR:
mmm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
W7S_06310 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
W7S_06310 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
W7S_06310 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
W7S_06310 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
Motif
Other DBs
NCBI-ProteinID:
AFJ34245
UniProt:
I2AAC1
LinkDB
All DBs
Position
complement(1296627..1300013)
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AA seq
1128 aa
AA seq
DB search
MQTLRGAAAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLL
GYALVQAIKKFPNMNRHYAEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKGCET
MRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVG
AMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDAFWDE
IFRELGNPYLPVRWSTDNPDSIVDKTARVMELIAAYRNRGHLMADIDPLRLDGSRFRSHP
DLEILNHGLTLWDLDRVFKVNGFAGSEYKKLRDVLGLLRDAYCRHIGVEYTHILDPEQQE
WLQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESIIPMMDAA
IDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLG
ATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDRRAEDQGDDKAFSVVP
MMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIANNQIGFTTAPEYSRSSEYCTDVA
KMIGAPIFHVNGDDPEACAWVAKLAVDFRQEFKKDVVIDMLCYRKRGHNEGDDPSMTNPA
MYDVVDIKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGALPSE
SVEADQMLPAGLSTAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKIDWA
FAELLALGSLVAEGKLVRLSGQDTRRGTFSQRHSVIIDRNTGAEFTPLQLLATNPDGTPT
GGKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKW
GQLSNVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDG
VQRPLIVFTPKSMLRNKAVVSDVKDFTEIKFRSVLEEPTYEDGIGDRGKVSRVLLTSGKL
YYELVARKAKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPSVQEYFWVQEEPANQGAWPR
FGLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFG
NT seq
3387 nt
NT seq
+upstream
nt +downstream
nt
ttgcagacgctgcgcggcgccgcggcggccgtcgtcaagaacatgtcggcgtcgctggag
gtgccgacggcgaccagcgtgcgcgccgttcccgccaagctgctgatcgacaaccggatc
gtcatcaacaaccaactcaagcgcacgcgcggcggcaagatctcgttcacccacctgctc
gggtacgcgctggtgcaggcgatcaagaagttcccgaacatgaatcggcactacgccgag
gtcgacgggaaacccaccgccgtcaccccggcgcacaccaacctggggctggcgatcgac
ctgcagggcaaggacggcaagcgttccttggtggtggccggcatcaagggctgcgagacc
atgcggttcgcgcagttcgtcaccgcctacgaagacatcgtgcggcgggcccgcgacggc
aagctgaccgccgaagactttgccggcgtgacgatttcgctgaccaacccgggcaccatc
ggcaccgtgcactcggtgccgcggctgatgaacggccagggcgccatcatcggcgtcggc
gccatggagtatcccgccgagttccagggcgccagcgaggaacgcatcgccgagctgggg
atcggcaagctgatcacgctgacctcgacctatgaccaccgcatcatccagggcgcggaa
tccggcgacttcttgcgcacgatccacgagatgctgctctcggatgcgttctgggacgag
atcttccgcgagctgggcaacccgtatctgccggtgcgctggagcaccgacaatccggac
tcgatcgtcgacaagaccgcccgggtgatggaattgattgcggcataccgcaatcgcggc
cacctgatggccgacatcgacccgctgcgcttggacggcagccggttccgcagccacccc
gacctcgagatcctcaaccacggcctgacgctgtgggatctcgatcgggtgttcaaagtc
aacggcttcgccgggtccgagtacaagaagctgcgcgatgtgctgggcctgctgcgcgac
gcctactgccgccacatcggcgtggagtacacccacatcctcgatcccgagcagcaggag
tggctgcagcagcgcgtcgagaccaagcacgtcaaaccgacggtggccgagcagaagttc
atcctgagcaaactgaacgcggccgaggccttcgagaccttcctgcagaccaaatacgtt
gggcagaaacggttttcacttgagggcgcggaaagcatcatcccgatgatggacgcggcg
atcgaccagtgcgccgagcacgggctcgacgaggtcgtcatcgggatgccgcaccgtggc
cggctcaacgtgctggccaacatcgtcggcaagccgtactcacagatcttttcggagttc
gagggcaacctcaacccggcgcaggcgcacggctccggcgacgtcaagtaccacctgggt
gccaccggcgtgtacctacagatgttcggcgacaacgacattcaggtgtcgctgaccgcc
aacccgtcgcacctggaagccgtcgacccggtgctggagggcctggtgcgcgccaagcag
gacctgctggacaggcgcgccgaggaccagggggacgacaaggccttctcggtggtgccg
atgatgctgcacggcgacgcggcgttcgccggtcagggcgtggtcgccgagaccctcaac
ctgacccacctgcccggttaccgcgtcggcggcaccatccacatcatcgccaacaaccag
atcggcttcaccaccgcgccggagtactcacggtccagcgagtactgcaccgacgtcgcg
aagatgatcggggcgccgatcttccacgtcaacggcgacgacccggaggcgtgcgcgtgg
gtggccaagctggccgtcgacttccggcaggagttcaagaaggacgtcgtcatcgacatg
ctgtgctaccgcaagcgcgggcacaacgaaggcgatgacccgtcgatgaccaaccccgcc
atgtacgacgtcgtcgacatcaagcgcggggtccgcaagagctacaccgaagccctgatc
ggccgcggcgacatctcgatgaaggaagccgaggacgccctgcgcgactaccagggccag
ctcgagcgggtgttcaacgaggtccgcgagctggagaagcacggcgcgctgcccagcgaa
tcggtggaggccgaccagatgctgcccgcgggcctgtccaccgcggtggacaaggcgctg
ctggcccgcatcggtgacgcgttcctggcgctacccgagggcttcacggcgcacccgcgg
gtgcagccggtcctggagaagcgccgggagatggcgtacgagggcaagatcgactgggcc
ttcgccgaactgctggcgctcggctcgctggtggccgagggcaagctggtgcgcctatcg
gggcaagacacccggcgcggcaccttctcgcagcgccactcggtgatcatcgaccgcaac
accggcgcggagttcacgccgctgcagctgctggcgaccaaccccgacggcacccccacc
ggcggcaagttcctggtctacgactccccgctgtcggaatacgcggccgtcggcttcgag
tacggctacaccgtgggcaacccggacgcgctcgtcctgtgggaagcccagttcggggac
ttcgtcaacggcgcgcagtcgatcatcgacgagttcatcagctccggcgaggccaagtgg
ggccagctgtccaacgtggtgctgctgctgccgcacggccacgaagggcagggtcccgac
cacacctccggccgcatcgagcgcttcctgcagctgtgggcggagggttcgatgacgatc
gcgatgccgtccacaccgtccaactatttccacttgttgcgccggcacgccctcgacggc
gtgcagcgcccgctgatcgtgttcacgcccaagtcgatgctgcgcaacaaggcggtggtc
agcgacgtcaaggacttcaccgagatcaagttccgctcggtgctcgaggagccgacctac
gaggacggcatcggcgatcgcggcaaggtcagcagggtcctgctgaccagcggcaagctc
tactacgagttggtggcccgcaaggccaaggacaaccgggacgacgtggcgatcgtgcgg
atcgagcagctcgccccgctgccgaagcgccggctgggcgaaacgctggaccgctacccg
agcgtccaggagtacttctgggtccaggaagagccggccaaccagggcgcgtggccgcgc
ttcggcctggaattgcccgagctgctgcccgacaagctgaccgggctcaagcggatttcc
cgccgggcgatgtcggccccgtcgtcgggctcgtcgaaggtgcacgccgtcgagcagcag
gagatcatcgacacggccttcggctga
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