Marmota marmota marmota (Alpine marmot): 107138607 Help Entry 107138607         CDS       T09644                                  Symbol Casp8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma01524   Platinum drug resistance mmma04115   p53 signaling pathway mmma04210   Apoptosis mmma04215   Apoptosis - multiple species mmma04217   Necroptosis mmma04620   Toll-like receptor signaling pathway mmma04621   NOD-like receptor signaling pathway mmma04622   RIG-I-like receptor signaling pathway mmma04623   Cytosolic DNA-sensing pathway mmma04625   C-type lectin receptor signaling pathway mmma04657   IL-17 signaling pathway mmma04668   TNF signaling pathway mmma04932   Non-alcoholic fatty liver disease mmma04936   Alcoholic liver disease mmma05010   Alzheimer disease mmma05016   Huntington disease mmma05022   Pathways of neurodegeneration - multiple diseases mmma05132   Salmonella infection mmma05134   Legionellosis mmma05142   Chagas disease mmma05145   Toxoplasmosis mmma05152   Tuberculosis mmma05160   Hepatitis C mmma05161   Hepatitis B mmma05162   Measles mmma05163   Human cytomegalovirus infection mmma05164   Influenza A mmma05165   Human papillomavirus infection mmma05167   Kaposi sarcoma-associated herpesvirus infection mmma05168   Herpes simplex virus 1 infection mmma05169   Epstein-Barr virus infection mmma05170   Human immunodeficiency virus 1 infection mmma05200   Pathways in cancer mmma05203   Viral carcinogenesis mmma05416   Viral myocarditis mmma05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmma00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     107138607 (Casp8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     107138607 (Casp8)    04215 Apoptosis - multiple species     107138607 (Casp8)    04217 Necroptosis     107138607 (Casp8)    04115 p53 signaling pathway     107138607 (Casp8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     107138607 (Casp8)    04621 NOD-like receptor signaling pathway     107138607 (Casp8)    04622 RIG-I-like receptor signaling pathway     107138607 (Casp8)    04623 Cytosolic DNA-sensing pathway     107138607 (Casp8)    04625 C-type lectin receptor signaling pathway     107138607 (Casp8)    04657 IL-17 signaling pathway     107138607 (Casp8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107138607 (Casp8)    05203 Viral carcinogenesis     107138607 (Casp8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     107138607 (Casp8)    05161 Hepatitis B     107138607 (Casp8)    05160 Hepatitis C     107138607 (Casp8)    05164 Influenza A     107138607 (Casp8)    05162 Measles     107138607 (Casp8)    05168 Herpes simplex virus 1 infection     107138607 (Casp8)    05163 Human cytomegalovirus infection     107138607 (Casp8)    05167 Kaposi sarcoma-associated herpesvirus infection     107138607 (Casp8)    05169 Epstein-Barr virus infection     107138607 (Casp8)    05165 Human papillomavirus infection     107138607 (Casp8)   09171 Infectious disease: bacterial    05132 Salmonella infection     107138607 (Casp8)    05134 Legionellosis     107138607 (Casp8)    05152 Tuberculosis     107138607 (Casp8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     107138607 (Casp8)    05142 Chagas disease     107138607 (Casp8)   09164 Neurodegenerative disease    05010 Alzheimer disease     107138607 (Casp8)    05016 Huntington disease     107138607 (Casp8)    05022 Pathways of neurodegeneration - multiple diseases     107138607 (Casp8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     107138607 (Casp8)    05416 Viral myocarditis     107138607 (Casp8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     107138607 (Casp8)    04932 Non-alcoholic fatty liver disease     107138607 (Casp8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     107138607 (Casp8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mmma01002]     107138607 (Casp8) Enzymes [BR:mmma01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      107138607 (Casp8) Peptidases and inhibitors [BR:mmma01002]  Cysteine peptidases   Family C14: caspase family    107138607 (Casp8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED TetR_C_7 PYRIN Motif Other DBs NCBI-GeneID:  107138607 NCBI-ProteinID:  XP_015336740 Ensembl:  ENSMMMG00000012315 LinkDB All DBs Position Unknown AA seq 520 aa AA seqDB search MVPEKVGSDAQTVIEETCEEGAAVVRDPGFASGYFSYLLTRMDFNKCLYDIGEQLGSDEL SSLKFLCLEYIPQKKQEPIKDALKLFQTLQEKGMLEENNLSFLKELLFRINRLDLLTTIL NTSKEDMVWELQIPGKAQISAYRVMLFQISEDVNKLELKSFKFLLSKDISKCKLDDDMSL LDIFIEMEKKLILGKRNLGTLKNICEQINKSLLKIIKNYEELSRERRMSPERSPDALSNG EESFGMLTLSDSPGEQDSDSQTSDKVYQMKNKPRGYCLIFNNYDFSMARKDMPKLHNIKD RKGSDLDEEALSKIFKELHFEIVCYKDSTAKEICEVLKFYQSEDHNNKDCFICCILSHGD EGIIYGTDGQKVSIFELTSYFTGSKCPSLAGKPKVFFIQACQGDNYQKGVLVETDSKQKD PYLEMDLSFQKSYIPDEADFLLGMATVSNCVSYRNPMEGTWYIQSLCQRLRERCPRGDDI LTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLD NT seq 1563 nt NT seq  +upstreamnt  +downstreamnt atggttccggaaaaggttggatcagatgcacagacagtcatagaagagacctgcgaggaa ggtgctgctgttgtgagggacccaggatttgcctctggttacttctcctaccttttgaca aggatggatttcaacaaatgtctttacgatattggggaacaactgggcagcgatgagttg tcctccctcaagttcttatgtctggaatatatcccacaaaagaagcaggagcccatcaag gatgccttgaagctattccagacacttcaggaaaagggaatgttggaggaaaacaatctg tccttcttgaaggagttgcttttccgaattaatagactggacctgctgaccactatcctg aataccagcaaggaggatatggtgtgggaacttcagattcctggcaaggcccagatttct gcctatagggtcatgctttttcagatttcagaagatgtaaacaaactggaattgaagtct tttaagtttcttttgagcaaggatatctccaagtgtaagctggatgacgacatgagcttg ctcgacattttcatagagatggagaagaagctcatcctaggaaagagaaacctgggaacc ctgaaaaatatctgtgaacaaatcaacaagagcctgctgaagatcattaagaattatgaa gaattaagcagagagagaagaatgagtcctgaaagaagtccagatgcactttcaaatggg gaggagtccttcgggatgttgacattgtcggactctccaggagaacaggacagtgactca cagacatcagacaaagtttaccaaatgaaaaacaaacctcggggatactgtttgatcttc aacaactatgattttagcatggcacggaaggatatgcccaagctccacaacattaaggat aggaaaggatcagatttggatgaagaggctttgagcaagatctttaaggagcttcatttt gaaatagtatgttacaaagattctacagccaaggaaatctgtgaagttctaaaattctac caaagtgaagaccacaacaataaagactgtttcatctgctgtatcctctcgcatggagac gagggcataatctatggcactgatggacagaaggtctccatctttgagctgacctcttat ttcactggttcaaagtgcccttcccttgctgggaaacctaaagtcttttttattcaggct tgtcaaggggataactaccagaaaggtgtacttgttgaaaccgactcaaagcagaaggac ccctacttagagatggatttatcatttcaaaagagttatatcccagatgaagctgacttt ctgttggggatggccactgtgagcaactgtgtttcctatcgaaatcccatggagggaacc tggtatatccagtccctttgccagagactgagagaaagatgtcctcgaggcgatgatatt ctcaccatcctgactgaagtgaactatgaagtgagcaataaggatgataagaagaacatg gggaaacagatgccacagcccacttttacattaaggaaaaaactcttctttcctcttgat tga

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