KEGG   Marmota marmota marmota (Alpine marmot): 107140113
Entry
107140113         CDS       T09644                                 
Symbol
Cdk4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma01522  Endocrine resistance
mmma04110  Cell cycle
mmma04115  p53 signaling pathway
mmma04151  PI3K-Akt signaling pathway
mmma04218  Cellular senescence
mmma04530  Tight junction
mmma04660  T cell receptor signaling pathway
mmma04933  AGE-RAGE signaling pathway in diabetic complications
mmma04934  Cushing syndrome
mmma05160  Hepatitis C
mmma05162  Measles
mmma05163  Human cytomegalovirus infection
mmma05164  Influenza A
mmma05165  Human papillomavirus infection
mmma05166  Human T-cell leukemia virus 1 infection
mmma05167  Kaposi sarcoma-associated herpesvirus infection
mmma05169  Epstein-Barr virus infection
mmma05200  Pathways in cancer
mmma05203  Viral carcinogenesis
mmma05212  Pancreatic cancer
mmma05214  Glioma
mmma05218  Melanoma
mmma05219  Bladder cancer
mmma05220  Chronic myeloid leukemia
mmma05222  Small cell lung cancer
mmma05223  Non-small cell lung cancer
mmma05224  Breast cancer
mmma05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    107140113 (Cdk4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    107140113 (Cdk4)
   04115 p53 signaling pathway
    107140113 (Cdk4)
   04218 Cellular senescence
    107140113 (Cdk4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    107140113 (Cdk4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    107140113 (Cdk4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107140113 (Cdk4)
   05203 Viral carcinogenesis
    107140113 (Cdk4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    107140113 (Cdk4)
   05225 Hepatocellular carcinoma
    107140113 (Cdk4)
   05214 Glioma
    107140113 (Cdk4)
   05220 Chronic myeloid leukemia
    107140113 (Cdk4)
   05218 Melanoma
    107140113 (Cdk4)
   05219 Bladder cancer
    107140113 (Cdk4)
   05224 Breast cancer
    107140113 (Cdk4)
   05222 Small cell lung cancer
    107140113 (Cdk4)
   05223 Non-small cell lung cancer
    107140113 (Cdk4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107140113 (Cdk4)
   05160 Hepatitis C
    107140113 (Cdk4)
   05164 Influenza A
    107140113 (Cdk4)
   05162 Measles
    107140113 (Cdk4)
   05163 Human cytomegalovirus infection
    107140113 (Cdk4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    107140113 (Cdk4)
   05169 Epstein-Barr virus infection
    107140113 (Cdk4)
   05165 Human papillomavirus infection
    107140113 (Cdk4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    107140113 (Cdk4)
   04934 Cushing syndrome
    107140113 (Cdk4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    107140113 (Cdk4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmma01001]
    107140113 (Cdk4)
Enzymes [BR:mmma01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     107140113 (Cdk4)
Protein kinases [BR:mmma01001]
 Serine/threonine kinases: CMGC group
  CDK family
   107140113 (Cdk4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 107140113
NCBI-ProteinID: XP_015338569
Ensembl: ENSMMMG00000010571
UniProt: A0A8C5ZBD8
LinkDB
Position
Unknown
AA seq 302 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEDD
PE
NT seq 909 nt   +upstreamnt  +downstreamnt
atggctacctcacgatatgagccagtggctgaaattggtgtcggtgcctatgggacggtg
tacaaagcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggagggggccttcccatcagcacagttcgtgaggtggccttattg
aggcgcctggaggcttttgaacatcccaacgttgtccggctgatggatgtctgtgccact
tcccggaccgaccgggaaatcaaggtgaccctagtgtttgagcatgttgaccaagactta
aggacctatttagacaaggcaccaccaccaggcttgccagccgagaccatcaaggatctg
atgcgccagtttctaagaggcctagattttcttcatgccaattgcatcgttcatcgggac
ctgaagccagaaaatattctggtgacaagtggtgggacagtcaagctggctgactttggc
ctggccagaatatacagctaccagatggcccttacacctgtggttgttacactctggtac
cgtgctcctgaagttcttctgcagtctacatatgcaacccctgtggacatgtggagcgtt
ggctgtatctttgcagagatgtttcgtcggaagcctctcttctgtggaaactctgaagct
gaccagttgggcaaaatctttgacctgatcgggctgcctccagaggatgactggccccga
gatgtatctctaccccgaggagcctttcccccaagaggacctcgcccggtgcagtcagtg
gtgcctgagatggaggagtctggagctcagttgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttatctacataaggaagatgat
ccagagtga

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