Marmota marmota marmota (Alpine marmot): 107142960
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Entry
107142960 CDS
T09644
Symbol
Ptk2
Name
(RefSeq) focal adhesion kinase 1 isoform X22
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01522
Endocrine resistance
mmma04012
ErbB signaling pathway
mmma04062
Chemokine signaling pathway
mmma04148
Efferocytosis
mmma04151
PI3K-Akt signaling pathway
mmma04360
Axon guidance
mmma04370
VEGF signaling pathway
mmma04510
Focal adhesion
mmma04670
Leukocyte transendothelial migration
mmma04810
Regulation of actin cytoskeleton
mmma04935
Growth hormone synthesis, secretion and action
mmma05100
Bacterial invasion of epithelial cells
mmma05135
Yersinia infection
mmma05146
Amoebiasis
mmma05163
Human cytomegalovirus infection
mmma05165
Human papillomavirus infection
mmma05170
Human immunodeficiency virus 1 infection
mmma05200
Pathways in cancer
mmma05202
Transcriptional misregulation in cancer
mmma05205
Proteoglycans in cancer
mmma05208
Chemical carcinogenesis - reactive oxygen species
mmma05222
Small cell lung cancer
mmma05417
Lipid and atherosclerosis
mmma05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
107142960 (Ptk2)
04370 VEGF signaling pathway
107142960 (Ptk2)
04151 PI3K-Akt signaling pathway
107142960 (Ptk2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
107142960 (Ptk2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
107142960 (Ptk2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
107142960 (Ptk2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
107142960 (Ptk2)
04062 Chemokine signaling pathway
107142960 (Ptk2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
107142960 (Ptk2)
09158 Development and regeneration
04360 Axon guidance
107142960 (Ptk2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107142960 (Ptk2)
05202 Transcriptional misregulation in cancer
107142960 (Ptk2)
05205 Proteoglycans in cancer
107142960 (Ptk2)
05208 Chemical carcinogenesis - reactive oxygen species
107142960 (Ptk2)
09162 Cancer: specific types
05222 Small cell lung cancer
107142960 (Ptk2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
107142960 (Ptk2)
05163 Human cytomegalovirus infection
107142960 (Ptk2)
05165 Human papillomavirus infection
107142960 (Ptk2)
09171 Infectious disease: bacterial
05135 Yersinia infection
107142960 (Ptk2)
05100 Bacterial invasion of epithelial cells
107142960 (Ptk2)
09174 Infectious disease: parasitic
05146 Amoebiasis
107142960 (Ptk2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107142960 (Ptk2)
05418 Fluid shear stress and atherosclerosis
107142960 (Ptk2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
107142960 (Ptk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107142960 (Ptk2)
01009 Protein phosphatases and associated proteins [BR:
mmma01009
]
107142960 (Ptk2)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107142960 (Ptk2)
Protein kinases [BR:
mmma01001
]
Non-receptor tyrosine kinases
FAK family
107142960 (Ptk2)
Protein phosphatases and associated proteins [BR:
mmma01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
107142960 (Ptk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
107142960
NCBI-ProteinID:
XP_015342006
Ensembl:
ENSMMMG00000005381
LinkDB
All DBs
Position
Unknown
AA seq
1062 aa
AA seq
DB search
MAAAYLDPNLNHTPHSSAKTHLGPGMERSPGAMERVLKVFHYFESNNEPTTWASIIRHGD
ATDVRGIIQKIVDSHRVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQ
TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLSIAENMADLIDGYCRLVSGATQSFII
RPQREGERALPSIPKLANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSKNYGIDEAR
DYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL
TMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA
LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPES
INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS
LMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPP
KPSRPGYPSPRSSEGFYPSPQHMVQSNHYQVSGYPGPHGLTAMAGSIYPGPASLLDQSES
WNHRPQEIPLWQPNMEDSASLDLRGMGQVLPAHLMEERLIRQQQEMEEDQRWLEKEERFL
KPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSS
PGDSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEY
VPMVKEVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNSDLGELISKMRLAQQCAMT
SLQQEYKKQMLTAAHALAVDAKNLLDAIDQARLKMLGQARPH
NT seq
3189 nt
NT seq
+upstream
nt +downstream
nt
atggcagctgcttaccttgaccccaacttgaaccacacgccacactcaagtgctaagacc
cacctgggtcctggcatggaacgttcccctggtgccatggagcgagtattgaaggtcttt
cattattttgaaagcaataatgagccaaccacctgggccagtattatcaggcacggagat
gctactgatgtcaggggcatcatccagaagatagtggacagccacagagtgaagcatgtg
gcttgctacgggttccgcctcagccacctgcggtcggaggaggttcactggctgcatgtg
gacatgggtgtctccagcgtgagggagaagtatgagcttgcccatcctccggaggagtgg
aaatatgaattaaggattcgttacttgccaaaaggatttctgaaccagtttactgaagac
aagccaactctgaatttcttctaccaacaggtaaagagcgactacatgctagagatagca
gaccaagtggaccaggaaattgctttgaagttgggttgcctagaaatacggcgatcatac
tgggagatgcgcggcaatgcactggaaaagaagtctaactatgaagtgttagaaaaagat
gttggtttaaagcgattttttcctaagagtttactggattctgtcaaggccaaaacttta
agaaaactgatccaacaaacatttagacagtttgccaaccttaatagagaagaaagtatt
ctgaaattctttgagatcctctctccagtgtacagatttgataaagaatgcttcaagtgt
gccctggggtcaagctggattatttcagtggaactggcaatcggccccgaagaagggatc
agttacctaacagacaagggctgcaatcccacacatctggctgacttcaaccaagtgcag
accattcagtattccaacagtgaagacaaagacagaaaaggaatgctacagctcaaaatc
gcaggtgcccccgagcctctgacagtgacagccccatccctgagcatcgccgagaacatg
gcggacctaatagacgggtactgccggctggtgagcggagccacgcagtccttcatcatc
agacctcagagagaaggtgaacgggcattgccatcaatacccaaattggccaacagtgag
aagcaaggtgtacggacacatgccgtctctgtgtcagagacagacgactatgccgagata
atcgatgaagaagatacttacaccatgccctcaaaaaactatggaatagatgaagctagg
gactatgagattcaaagagaaagaatagaactcggacgctgtattggagaaggccagttt
ggagatgtgcatcaaggcgtgtacatgagtccagagaatccagctttggctgtcgcaatt
aaaacatgtaaaaactgtacttcggacagcgtgagagagaaattcctccaagaagcctta
acaatgcgtcagtttgaccatcctcacattgtgaagttgattggcgtcatcacagagaac
cccgtgtggataatcatggagctgtgcacactgggagagctgaggtcatttttgcaagta
aggaaatacagcttggatctggcatctctgatcttatatgcctatcagctcagtaccgca
ctggcatatctggagagcaaaagatttgtacacagggacattgctgctcgaaatgtcctg
gtatcctcaaatgattgtgtaaaattaggagacttcggattatctcggtacatggaagac
agtacttactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtca
atcaattttcgacgttttacctcagctagtgacgtgtggatgtttggtgtatgtatgtgg
gagattctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggt
cgaattgaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagc
cttatgacgaaatgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaa
gcgcagctcagcacgatcctggaggaagagaaggctcagcaggaagaacggatgaggatg
gagtccagaagacaggccaccgtgtcttgggactctggagggtccgacgaagcaccaccc
aagcccagcagacctggttaccctagtccgcgctccagtgaaggattttaccccagcccg
cagcacatggtgcagagcaatcattatcaggtctctggctaccctggtccacacggactc
acagccatggctggcagcatctaccccggcccagcatctctcttggaccaatcagaatcg
tggaatcacaggccccaggagatacccctgtggcagcccaacatggaggactcagcatcg
ttggacctgagaggaatggggcaggtgttgcccgcccacctgatggaagagcgactgatc
cgacagcagcaggaaatggaagaagatcagcgctggctggagaaagaggagagatttctg
aaacctgatgtgaggctatctcgaggcagcattgacagggaggacgggagtcttcagggg
ccgactggaaaccaacacatctatcagcctgtgggcaaaccagatcctgcggctccacca
aagaaacctccacgccccggagcccccggccacctgggcagcctcgccagcctcagcagc
cctggggacagctacaacgagggtgtcaagccatggaggcttcaaccccaggaaatcagt
ccccctcccactgccaacctggaccggtccaatgacaaggtgtatgagaacgtgacgggc
ctggtgaaagctgtcattgagatgtccagtaaaatccagccagccccacccgaggagtac
gtccctatggtgaaggaagttggcttggccctgcggacactattggctaccgtggatgag
accattcctgtcctcccagccagcacacaccgagagatcgagatggcacagaagctgctc
aactctgacctgggagagctcatcagcaagatgcggctggcccagcagtgcgccatgacc
agcctgcagcaggagtacaagaagcagatgctgactgccgcccacgccctcgcagtggat
gccaagaacctgctggatgccattgaccaggcgagactgaagatgcttgggcaggcaagg
ccacattga
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integrated database retrieval system
