Marmota marmota marmota (Alpine marmot): 107145057
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Entry
107145057 CDS
T09644
Symbol
Jak3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma04062
Chemokine signaling pathway
mmma04151
PI3K-Akt signaling pathway
mmma04217
Necroptosis
mmma04550
Signaling pathways regulating pluripotency of stem cells
mmma04630
JAK-STAT signaling pathway
mmma04658
Th1 and Th2 cell differentiation
mmma04659
Th17 cell differentiation
mmma05161
Hepatitis B
mmma05162
Measles
mmma05166
Human T-cell leukemia virus 1 infection
mmma05169
Epstein-Barr virus infection
mmma05200
Pathways in cancer
mmma05203
Viral carcinogenesis
mmma05223
Non-small cell lung cancer
mmma05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107145057 (Jak3)
04151 PI3K-Akt signaling pathway
107145057 (Jak3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
107145057 (Jak3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
107145057 (Jak3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
107145057 (Jak3)
04659 Th17 cell differentiation
107145057 (Jak3)
04062 Chemokine signaling pathway
107145057 (Jak3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107145057 (Jak3)
05203 Viral carcinogenesis
107145057 (Jak3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
107145057 (Jak3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
107145057 (Jak3)
05161 Hepatitis B
107145057 (Jak3)
05162 Measles
107145057 (Jak3)
05169 Epstein-Barr virus infection
107145057 (Jak3)
09163 Immune disease
05340 Primary immunodeficiency
107145057 (Jak3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107145057 (Jak3)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107145057 (Jak3)
Protein kinases [BR:
mmma01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107145057 (Jak3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
ABC1
Kdo
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
107145057
NCBI-ProteinID:
XP_015344379
Ensembl:
ENSMMMG00000000693
LinkDB
All DBs
Position
Unknown
AA seq
993 aa
AA seq
DB search
MAPPSEEMPLISQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVRAAKA
SGILPVYHSLFALATEDLSCWFPPSHVFSVEDAGTQVLVYRLRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRSDLLSGRLHVGLSLQEQGECLSLAVLDVARMACEQGQR
PAQLLKTVSYKACLPPGLRDLIQGLSFVTRRRIRTTVRCALRRVAACQADRHSLMAKYIM
DLERLDPAGTTETFRVGLSGAAGGQDGQGLLRVAGGSGISWSPAAQEVFQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTITRTDNQILEAEFPGLPEALSFLALVDGYFRLICDSRHFFC
KEVAPPRLLEEVAEQCYGPITLDFAINKLKEGGSLPGSYVLRRSPQDFDSFLLTVCVQTP
LGPDYKGCLIRRDPVGTVSLVGLGRPHSSLRQLLAACWDGGLHVDGVALQLSSCCTPRPK
EKTNLTVVRRGCGPPSTSPAQPQFQHKLNQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEAVDGEARATEVLLKVMDAKHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDSIMVQ
EFVLLGAIDTYLRKHGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGSSPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQETQMLGLEADKWGFGATVWEVFS
GIPMPLNHLDPPKKLKFYEDRQQLPAPKWTELALLIQQCMAYEPGQRPSFRAVIRDLNSL
ITSDYELLSDPTPGTLTPRDGLWSGAQLYACQDPTIFEERHLKYISQLGKGNFGNVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKAMHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDSSRLLLYASQICKGMEYLGSRRCVHRDLAARNILVENE
AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFW
NT seq
2982 nt
NT seq
+upstream
nt +downstream
nt
atggcacctccaagtgaggagatgcccctgatctcccagcgctcctgcagcctctcctcc
tcggaggctggtgcgctccacgtgctgctgcctcctcggggtcccgggcctcctcagagg
ctgtctttctcctttggggaccactcggctgaggaactgtgtgtgcgggctgccaaggcc
agtggcatcctgcccgtgtaccactcactctttgccttggccacggaggacttgtcttgc
tggttccctccgagccacgtcttctctgtggaagatgcgggcacccaagtcctagtctac
agactgcgcttttactttcccaactggtttgggctggagaagtgccaccgctttgggcta
cgcaaggacttggccagtgccatcctggacctgcccgtcctggaacacctctttgcccag
caccgcagtgacctgctgagtgggcgcctgcacgtgggtctcagcctccaggagcagggc
gagtgtctcagcctggccgtgctggacgtggcccggatggcctgtgagcagggccagcgg
cctgcccagctcctgaagaccgtcagctacaaggcctgcctgccgcctggcctgcgcgac
ctgatccagggtctgagcttcgtgacccggagacggattcggaccacggtgcgctgcgcc
ttgcgccgtgtggcggcctgccaggcggaccggcactcgctcatggccaagtacatcatg
gacctggagcggctggaccctgctgggaccaccgagaccttccgcgtcggtctgtccggg
gccgcgggtggccaggatgggcaggggttgctccgtgtggctggtggcagcggcatctcc
tggagtccggcagcacaggaggtcttccagcccttctgtgactttccagaaatcgtggac
atcagcatcaagcaagccccacgggttggcccggccggggagcaccgcctggtcactatc
accaggacagacaaccagatcctggaggccgagttcccggggctgcccgaggcgctgtcc
ttcttggctctggtggacggttacttccgcctgatttgcgactcccgccacttcttctgc
aaggaggtggcaccgccacggctgctggaggaagtggccgagcagtgctatggccccatc
accctggactttgccatcaacaagctcaaggaggggggctcacttcccggctcctacgtg
ctgcggcgcagcccccaggacttcgacagcttcctcctcactgtgtgtgtccagacaccc
ctcggccctgactacaagggctgcctcatccgccgagaccctgtaggaaccgtgtcgctg
gtcggccttggccgtcctcacagcagccttcggcagctgctggcagcctgctgggacggc
gggcttcacgttgatggagttgccctgcagcttagctcctgctgcacccccagacccaaa
gaaaagaccaacttgactgtggtccggaggggctgcggcccaccctccacctcccctgct
cagccccagttccaacataagctgaatcagatgacgttccacaagatccctgccgacagc
ctggagtggcatgagaacctgggccacgggtccttcaccaagatttaccggggatgtcgc
cacgaggctgtggacggggaggcccgggcgacggaggtgctcctgaaggtcatggacgcc
aagcacaggaactgcatggagtccttcctggaagctgcgagcttgatgagtcaggtgtcc
tacccgcatctggtgctgctccacggcgtgtgcatggctggagacagcatcatggtgcag
gaattcgtcctcctgggagccatagacacctacctgcgcaagcatggccacctggtgcca
gccagctggaagctgcaggtggtcaaacagctggcctacgccctcaactacctggaggac
aaaggcctccctcacggcaacgtctcagcccggaaggtgctcctggctcgggagggggct
gacgggagctcgcctttcatcaagctgagtgaccctggtgtcagccccactgtgctaagc
ctggaaatgctcactgacaggatcccctgggtggcccccgagtgtctccaggagacccag
atgcttggcttggaagccgacaagtgggggtttggtgcaacagtctgggaggtgttcagc
gggatcccgatgcccctcaaccacctggacccccccaagaaactcaagttttatgaggac
cggcagcagctgccggcccccaagtggacagagctggccctgctgatccagcagtgcatg
gcctacgagccaggccagaggccctccttccgagctgtcatccgggacctcaacagcctc
atcacttcagactatgagctcctctcagacccaacccctggtaccctgacgccccgcgat
gggctgtggagtggtgcccagctctatgcctgccaggaccccacgatctttgaggaaaga
cacctcaagtacatctcacagttgggaaagggcaactttggcaatgtggaattgtgccgc
tatgacccgctgggtgacaacacgggcgccctggtggctgtgaagcagctgcagcacagt
gggccagatcagcagagggacttccagcgggagatccagatcctcaaagccatgcacagt
gactttattgtgaagtaccgtggtgtcagctatggccccggtcgccagagcttgcggctg
gtcatggagtacctgcccagcggatgcctgcgtgactttctgcagaggcaccgcgcacgc
ctggactcgagccgcctcctcctctacgcctcgcagatctgcaagggcatggagtacctg
ggctcccgccgctgcgtgcatcgcgacctggcggcccggaacatcctggtggagaacgag
gctcacgtcaagatcgccgacttcggcttggccaagctgctgccgctcgacaaggactac
tacgtggttcgcgagcccggccagagccccatcttctggtag
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