Marmota marmota marmota (Alpine marmot): 107146235 Help Entry 107146235         CDS       T09644                                  Symbol Adcy1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma00230   Purine metabolism mmma01100   Metabolic pathways mmma01522   Endocrine resistance mmma04015   Rap1 signaling pathway mmma04020   Calcium signaling pathway mmma04022   cGMP-PKG signaling pathway mmma04024   cAMP signaling pathway mmma04062   Chemokine signaling pathway mmma04072   Phospholipase D signaling pathway mmma04081   Hormone signaling mmma04082   Neuroactive ligand signaling mmma04114   Oocyte meiosis mmma04211   Longevity regulating pathway mmma04213   Longevity regulating pathway - multiple species mmma04261   Adrenergic signaling in cardiomyocytes mmma04270   Vascular smooth muscle contraction mmma04371   Apelin signaling pathway mmma04540   Gap junction mmma04611   Platelet activation mmma04713   Circadian entrainment mmma04714   Thermogenesis mmma04720   Long-term potentiation mmma04723   Retrograde endocannabinoid signaling mmma04724   Glutamatergic synapse mmma04725   Cholinergic synapse mmma04727   GABAergic synapse mmma04750   Inflammatory mediator regulation of TRP channels mmma04911   Insulin secretion mmma04912   GnRH signaling pathway mmma04913   Ovarian steroidogenesis mmma04914   Progesterone-mediated oocyte maturation mmma04915   Estrogen signaling pathway mmma04916   Melanogenesis mmma04918   Thyroid hormone synthesis mmma04921   Oxytocin signaling pathway mmma04923   Regulation of lipolysis in adipocytes mmma04925   Aldosterone synthesis and secretion mmma04926   Relaxin signaling pathway mmma04927   Cortisol synthesis and secretion mmma04928   Parathyroid hormone synthesis, secretion and action mmma04934   Cushing syndrome mmma04935   Growth hormone synthesis, secretion and action mmma04970   Salivary secretion mmma04971   Gastric acid secretion mmma04972   Pancreatic secretion mmma04976   Bile secretion mmma05032   Morphine addiction mmma05142   Chagas disease mmma05146   Amoebiasis mmma05163   Human cytomegalovirus infection mmma05166   Human T-cell leukemia virus 1 infection mmma05200   Pathways in cancer mmma05207   Chemical carcinogenesis - receptor activation mmma05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmma00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107146235 (Adcy1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107146235 (Adcy1)    04072 Phospholipase D signaling pathway     107146235 (Adcy1)    04024 cAMP signaling pathway     107146235 (Adcy1)    04022 cGMP-PKG signaling pathway     107146235 (Adcy1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107146235 (Adcy1)    04081 Hormone signaling     107146235 (Adcy1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107146235 (Adcy1)    04062 Chemokine signaling pathway     107146235 (Adcy1)   09152 Endocrine system    04911 Insulin secretion     107146235 (Adcy1)    04923 Regulation of lipolysis in adipocytes     107146235 (Adcy1)    04913 Ovarian steroidogenesis     107146235 (Adcy1)    04915 Estrogen signaling pathway     107146235 (Adcy1)    04921 Oxytocin signaling pathway     107146235 (Adcy1)    04926 Relaxin signaling pathway     107146235 (Adcy1)    04935 Growth hormone synthesis, secretion and action     107146235 (Adcy1)    04918 Thyroid hormone synthesis     107146235 (Adcy1)    04928 Parathyroid hormone synthesis, secretion and action     107146235 (Adcy1)    04925 Aldosterone synthesis and secretion     107146235 (Adcy1)    04927 Cortisol synthesis and secretion     107146235 (Adcy1)   09154 Digestive system    04970 Salivary secretion     107146235 (Adcy1)    04971 Gastric acid secretion     107146235 (Adcy1)    04972 Pancreatic secretion     107146235 (Adcy1)    04976 Bile secretion     107146235 (Adcy1)   09156 Nervous system    04724 Glutamatergic synapse     107146235 (Adcy1)    04727 GABAergic synapse     107146235 (Adcy1)    04725 Cholinergic synapse     107146235 (Adcy1)    04720 Long-term potentiation     107146235 (Adcy1)    04723 Retrograde endocannabinoid signaling     107146235 (Adcy1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107146235 (Adcy1)   09149 Aging    04211 Longevity regulating pathway     107146235 (Adcy1)    04213 Longevity regulating pathway - multiple species     107146235 (Adcy1)   09159 Environmental adaptation    04713 Circadian entrainment     107146235 (Adcy1)    04714 Thermogenesis     107146235 (Adcy1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107146235 (Adcy1)    05207 Chemical carcinogenesis - receptor activation     107146235 (Adcy1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107146235 (Adcy1)    05163 Human cytomegalovirus infection     107146235 (Adcy1)   09174 Infectious disease: parasitic    05146 Amoebiasis     107146235 (Adcy1)    05142 Chagas disease     107146235 (Adcy1)   09165 Substance dependence    05032 Morphine addiction     107146235 (Adcy1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107146235 (Adcy1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107146235 (Adcy1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107146235 (Adcy1) Enzymes [BR:mmma01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107146235 (Adcy1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA DUF6688 DUF6594 Motif Other DBs NCBI-GeneID:  107146235 NCBI-ProteinID:  XP_015345783 Ensembl:  ENSMMMG00000014821 UniProt:  A0AAJ7AQY5 LinkDB All DBs Position Unknown AA seq 894 aa AA seqDB search MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYLSRLLEARQTELEMADL NFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILAALFGLVYLLMIPQSVAVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSQSNS SLVVLAAGGRRTVLPALPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYIL VLELSGYTKAEGGGVSGRSYEPIVAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDD MERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELD GNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAKKSIS SHLSTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNV ASRMDSTGVQGRIQVTEEVHRLLRKCAYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSHP RPLHLERKMCAYGRAGGQARRPPLCPAAGPPIRAGLPPVPTGQYLPPAAAGKEA NT seq 2685 nt NT seq  +upstreamnt  +downstreamnt atgtatggcgtcttcgtgcggatcctgactgagcgctctcagaggaaggcctttctgcaa gcccggagctgcattgaggaccggctacggttggaggatgagaacgagaaacaggagcgg ctgcttatgagcctccttccccggaatgttgccatggagatgaaggaagacttcttgaag ccccctgagaggattttccacaagatttacatccagaggcatgacaatgtgagcatcctg tttgcggacatcgtgggcttcacaggcttggcatcccagtgcacggcccaggagctggtg aaactgctcaatgaactctttggcaagttcgacgagttagccacggagaaccactgtcgt cgcatcaagattcttggggactgctactactgtgtttcaggcctaacccagcccaagact gaccatgcccattgctgcgtggagatggggctcgacatgattgacaccatcacgtctgtg gctgaggccactgaggtggacctgaacatgcgtgtggggctacacactggcagggtcctc tgtggtgttctgggcctgcgcaagtggcagtacgatgtgtggtccaatgatgtgaccctg gccaacgtcatggaggctgccggcctgcctgggaaggttcatatcacaaagacaaccctt gcatgcttgaatggagattacgaggtggagccaggccatggacatgagaggaacagcttc ctgaaaactcataacattgagaccttctttattgtgccatcccatcggagaaagatattt ccaggcttgattctctcagatataaagccggccaagaggatgaagtttaagactgtctgc tacctgctggtgcagctcatgcactgccggaagatgttcaaggctgagatccccttctcc aatgtcatgacctgtgaagacgatgacaagcggagagcattgagaacagcatcagaaaaa cttcgaaaccgctcgtctttctctacaaatgtggtctacaccacaccaggcacgcgtgtc aataggtatttaagccgcctcctggaagcccgccagacggagctggagatggcggatctg aatttcttcaccttgaagtacaaacatgttgaacgggagcaaaagtaccaccagcttcag gacgagtatttcaccagcgctgtcgtccttgccctcatcctggctgccttatttggcctt gtctaccttcttatgattccacagagtgtggctgtcctgctcctgctggtgttctgtatc tgcttcctggtggcctgtgtcctctacctgcacatcacccgggtccagtgttttccaggg tgcctgacgattcagattcgtaccgtcttgtgcatattcatagtggtcttaatctattct gtagcccaaggatgtgtggtgggctgcctaccctgggcctggagctcccagtccaacagc tccctggtggtccttgcggctgggggccggcgcactgtgctgcctgccttgccctgtgag tctgcacatcacgccctgctctgctgcctggtgggtaccctcccgctagccatattcctg cgggtgtcctccttgccaaagatgatcctgctgtctggactcaccacatcctacatcctc gttctggagctcagcggatacaccaaggccgagggcggtggtgtctctgggcgcagctac gagccgatcgtggccatcctgctgttttcgtgcacgctggccctgcacgccaggcaggtg gacgtgaggctgcggctggactacctctgggcagcacaggcagaagaggagcgggatgat atggagagggtaaagctggacaacaagaggatcctctttaacctccttccagcccacgtt gcacagcacttcctcatgtccaatccccggaatatggacctctactaccagtcctactcc caggtgggtgtcatgtttgcctctatccccaacttcaatgacttctacatcgagctggat ggcaacaacatgggagtggagtgtctgcgactccttaacgagattatcgctgactttgat gagctcatggacaaagacttttataaggatctagagaagatcaagaccattggaagcact tacatggctgcagtggggctggcgcccacagcaggaaccagagctaagaagtccatctcc tcccacctcagcacactggctgactttgctattgacatgtttgacgtcttggatgaaatc aactaccagtcatacaatgactttgtcctccgagttggtatcaatgttggccctgtggtg gctggagtgattggtgctcgcaggccccagtacgacatctggggaaacacggtcaatgtg gccagtcggatggacagcaccggagtccagggcagaatccaggtgactgaggaggtgcac cggctgctgagaaagtgtgcctaccattttgtgtgccgaggcaaagtcagtgtcaaaggc aagggggagatgctgacgtacttcctagaaggcaggactgatggaaatggctcccacccc aggcctcttcacttggagcgcaagatgtgtgcttatgggagagctggaggccaggccaga cggcccccactgtgtcccgcagcaggcccaccaatcagggcagggctccccccagttccc acaggccagtacctgccacctgcagcagcggggaaggaagcttaa

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