Marmota marmota marmota (Alpine marmot): 107153335
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Entry
107153335 CDS
T09644
Symbol
Pten
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00562
Inositol phosphate metabolism
mmma01100
Metabolic pathways
mmma01521
EGFR tyrosine kinase inhibitor resistance
mmma04068
FoxO signaling pathway
mmma04070
Phosphatidylinositol signaling system
mmma04071
Sphingolipid signaling pathway
mmma04115
p53 signaling pathway
mmma04140
Autophagy - animal
mmma04150
mTOR signaling pathway
mmma04151
PI3K-Akt signaling pathway
mmma04218
Cellular senescence
mmma04510
Focal adhesion
mmma04931
Insulin resistance
mmma05165
Human papillomavirus infection
mmma05166
Human T-cell leukemia virus 1 infection
mmma05200
Pathways in cancer
mmma05206
MicroRNAs in cancer
mmma05208
Chemical carcinogenesis - reactive oxygen species
mmma05213
Endometrial cancer
mmma05214
Glioma
mmma05215
Prostate cancer
mmma05218
Melanoma
mmma05222
Small cell lung cancer
mmma05224
Breast cancer
mmma05225
Hepatocellular carcinoma
mmma05230
Central carbon metabolism in cancer
mmma05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mmma05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
107153335 (Pten)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
107153335 (Pten)
04070 Phosphatidylinositol signaling system
107153335 (Pten)
04071 Sphingolipid signaling pathway
107153335 (Pten)
04151 PI3K-Akt signaling pathway
107153335 (Pten)
04150 mTOR signaling pathway
107153335 (Pten)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
107153335 (Pten)
09143 Cell growth and death
04115 p53 signaling pathway
107153335 (Pten)
04218 Cellular senescence
107153335 (Pten)
09144 Cellular community - eukaryotes
04510 Focal adhesion
107153335 (Pten)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107153335 (Pten)
05206 MicroRNAs in cancer
107153335 (Pten)
05208 Chemical carcinogenesis - reactive oxygen species
107153335 (Pten)
05230 Central carbon metabolism in cancer
107153335 (Pten)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
107153335 (Pten)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
107153335 (Pten)
05214 Glioma
107153335 (Pten)
05218 Melanoma
107153335 (Pten)
05215 Prostate cancer
107153335 (Pten)
05213 Endometrial cancer
107153335 (Pten)
05224 Breast cancer
107153335 (Pten)
05222 Small cell lung cancer
107153335 (Pten)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
107153335 (Pten)
05165 Human papillomavirus infection
107153335 (Pten)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107153335 (Pten)
09167 Endocrine and metabolic disease
04931 Insulin resistance
107153335 (Pten)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107153335 (Pten)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmma01009
]
107153335 (Pten)
Enzymes [BR:
mmma01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
107153335 (Pten)
3.1.3.48 protein-tyrosine-phosphatase
107153335 (Pten)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
107153335 (Pten)
Protein phosphatases and associated proteins [BR:
mmma01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
107153335 (Pten)
BRITE hierarchy
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
107153335
NCBI-ProteinID:
XP_015354355
Ensembl:
ENSMMMG00000018507
UniProt:
A0A8C6EWE6
LinkDB
All DBs
Position
Unknown
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSERVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatggg
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgaaagacattatgacaccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataacccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacggactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattgcctgtatgtggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggataaaatgtttcatttttgggtaaatacgttcttcata
ccaggaccagaggaaacctcagaaagagtagaaaatggaagtctatgtgatcaagaaatc
gatagtatttgcagtatagaacgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatcttgacaaagcaaataaagacaaggccaaccgatatttttctccaaat
tttaaggtgaaactgtattttacaaaaacagtagaggagccatcaaatccagaggctagc
agttcaacttctgtaacaccggatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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