Marmota marmota marmota (Alpine marmot): 107154239 Help Entry 107154239         CDS       T09644                                  Symbol Hk2 Name (RefSeq) hexokinase-2 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma00010   Glycolysis / Gluconeogenesis mmma00051   Fructose and mannose metabolism mmma00052   Galactose metabolism mmma00500   Starch and sucrose metabolism mmma00520   Amino sugar and nucleotide sugar metabolism mmma00524   Neomycin, kanamycin and gentamicin biosynthesis mmma01100   Metabolic pathways mmma01200   Carbon metabolism mmma01250   Biosynthesis of nucleotide sugars mmma04066   HIF-1 signaling pathway mmma04910   Insulin signaling pathway mmma04930   Type II diabetes mellitus mmma04973   Carbohydrate digestion and absorption mmma05230   Central carbon metabolism in cancer Module mmma_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mmma_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc mmma_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:mmma00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     107154239 (Hk2)    00051 Fructose and mannose metabolism     107154239 (Hk2)    00052 Galactose metabolism     107154239 (Hk2)    00500 Starch and sucrose metabolism     107154239 (Hk2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     107154239 (Hk2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     107154239 (Hk2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     107154239 (Hk2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     107154239 (Hk2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     107154239 (Hk2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     107154239 (Hk2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     107154239 (Hk2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmma04131]     107154239 (Hk2) Enzymes [BR:mmma01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      107154239 (Hk2) Membrane trafficking [BR:mmma04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     107154239 (Hk2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  107154239 NCBI-ProteinID:  XP_015355340 Ensembl:  ENSMMMG00000005126 UniProt:  A0A8C5YW91 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHMIACLFTELNHNQVQKVEQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGALNDIRTEFDREIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFQGKLSPELLTTGSFETKDVSDIEDDKDGIRKAYQVLVRLG LNPLQEDCVATHRICQIVSTRSANLCAATLAAVLRRIKENKGEDRLRSTIGVDGSVYKKH PHFAKHLHKAVRRLVPDCDIRFLRSEDGSGKGAAMVTAVAYRLADQQRARQNTLEPLKLS HEQLLEVKRRMKLEMERGLSKETHSIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGRMCVNMEWGAFGDNGCLDD FRTEFDKAVDDLSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCEVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgattgcctcgcatatgatcgcctgcctcttcacggagctcaaccataaccaagtgcag aaagttgagcagtatctctaccacatgcgtctctccgatgaaacccttttggagatttct aagcggttccgcaaggagatggaaaaagggcttggagccaccacccaccccactgcttca gtgaaaatgctgccaacttttgtgaggtccaccccagatgggacagaacacggagagttc ctggctctggatcttggagggaccaacttccgtgtactccgtgtgagagtaacggacaat gggctccagaaggttgagatggagaaccagatctacgccatccctgaggacatcatgcga ggcagtggcactcagctgtttgaccacattgctgaatgcctggccaacttcatggataag ctccaaatcaaagacaagaagctcccattgggctttaccttctcattcccctgccaccag actaagctagatgagagtttcctggtctcatggaccaagggcttcaagtccagtggtgtg gaaggcagagacgtggtggctctgatccggaaggccatccagcggagaggggactttgat attgacattgtggctgtggtgaatgacacggttgggaccatgatgacttgtggttatgat gaccagaactgtgagattggtctcattgtgggcactggcagcaatgcctgctacatggag gaaatgcgtcacatcgacatggtggagggcgacgaggggcggatgtgtatcaacatggag tggggggcctttggggacgatggcgcgctcaatgacatccgcacggaatttgaccgagag atcgacatgggctcgctgaatcctgggaagcaactgtttgagaagatgatcagtgggatg tacatgggggagctggtaaggctcatcctggtgaagatggccaaggaagagctgctgttc caggggaagctcagcccagaactgcttaccacaggcagcttcgaaaccaaagatgtctca gatattgaagacgataaggatggcatccggaaggcctaccaggtgctggtgcggctgggt ctgaatccattgcaggaggactgtgtggccactcaccggatctgccagattgtgtccaca cgctcagccaacctgtgtgcagccaccctggctgctgtgctgcggcgtatcaaggagaac aagggcgaggatcggctgcgctccaccattggggttgatggctccgtctacaagaaacac cctcattttgccaagcatcttcacaaggctgtacgtcggctggtgcctgactgcgacatt cgcttcctccgctctgaggatggcagcggcaaaggggcagccatggtgaccgcggtggcg taccgactggctgatcaacaaagagcccgccagaataccctggagcctctaaaactgagc catgagcagctgctggaggtcaagaggaggatgaagcttgaaatggagcgaggtctgagc aaggagacgcactccatcgcccctgtgaagatgctgcccacttacgtgtgtgctaccccc gatggcacagagaaaggggacttcttggccttggaccttggaggaaccaatttccgggtc ctgctggtgcgtgtgcgaaatgggaagcggcgaggagtagagatgcacaacaagatctac tccatcccacaggaggtcatgcatggcacaggcgaggagctctttgaccacatcgtccag tgcatcgctgacttcctggagtacatgggcatgaagggtgtgtctctgcctctgggtttc accttctccttcccctgccagcagaacagcttggatgagagtattctccttaagtggacc aaaggcttcaaggcatctggatgcgagggtgaagacgtggtcaccctgctgaaggaagcg atccaccggcgagaggagtttgacctggacgtggtggctgtggttaatgacacagttgga actatgatgacgtgtggctatgaagaccctcactgtgaggttggcctcattgttggcacg ggtagcaacgcctgctacatggaggagatgcgcaatgtggagctggtggatggagaagag gggcggatgtgtgtcaacatggagtggggggccttcggggacaatggatgcctggatgac ttccgcacggaatttgacaaggctgtcgatgatctttcgctcaacccaggcaaacagagg tttgagaagatgatcagtggcatgtacttgggcgagattgtccgtaacatccttatcgat ttcaccaagcgagggctgctcttccgcggccgcatctcagagcggctcaagacaagggga atctttgaaacaaagttcttgtctcagattgagagcgattgcctggccctgctgcaggtc cgtgccatcctgcaccacttgggcctcgagagcacctgtgacgacagcatcattgtcaag gaggtgtgcacggtagtggcacggcgggcagcccagctctgtggcgcaggcatggctgcc gttgtggacaagatacgggaaaaccgtgggctggacaccctcaaagtgacagtgggtgtg gatgggaccctctacaagctacatcctcattttgccaaagtcatgcatgagacggtgaag gacctggcccccaaatgtgaggtgtccttcctggagtcagaggacggcagcgggaagggg gccgcgctcatcactgccgtggcctgtcgcatccgtgaggccggacagcgatag

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