Marmota marmota marmota (Alpine marmot): 107154522 Help Entry 107154522         CDS       T09644                                  Symbol Acacb Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma00061   Fatty acid biosynthesis mmma00620   Pyruvate metabolism mmma00640   Propanoate metabolism mmma01100   Metabolic pathways mmma04152   AMPK signaling pathway mmma04910   Insulin signaling pathway mmma04920   Adipocytokine signaling pathway mmma04922   Glucagon signaling pathway mmma04931   Insulin resistance mmma04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:mmma00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     107154522 (Acacb)    00640 Propanoate metabolism     107154522 (Acacb)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     107154522 (Acacb)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     107154522 (Acacb)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     107154522 (Acacb)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     107154522 (Acacb)    04922 Glucagon signaling pathway     107154522 (Acacb)    04920 Adipocytokine signaling pathway     107154522 (Acacb)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     107154522 (Acacb)    04931 Insulin resistance     107154522 (Acacb) Enzymes [BR:mmma01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      107154522 (Acacb)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      107154522 (Acacb)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      107154522 (Acacb) BRITE hierarchy Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C Motif Other DBs NCBI-GeneID:  107154522 NCBI-ProteinID:  XP_048640848 Ensembl:  ENSMMMG00000018633 LinkDB All DBs Position Unknown AA seq 2412 aa AA seqDB search MVLLLFLFCLIFYCLTFSWLKIWGKMTDARPATNGQLEASFTLSQEASPASDRSEDNLQG NGSATLLPGTPDGAELATLPSPEGTRGQRGSRPPVHQRPPRNPVSSDGTWPSPEPTASGT GTQGPGAPGTNGLSSPARPQGQPARALSRADEKQAHLKRQLLTSFILGSFDDNSSDDDSG ASSFRESPRRGSRASLGAASPDSPHTASEPETSVPTMRPSMSGLHLVKRGREHKKLDAHR DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT PEDLKANAEYIKMADQYVPVPGGTNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL PELLCKHGIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWAEDDWQQGR PVSVPEDVYNQGCVRDVDEGLEAAEKIGFPVMIKASEGGGGKGIRKAESAEDFPMLFRQV QSELPGSPIFLMKLAQHARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAT PALLEFMEQCAVRLAKTVGYVSAGTVEYLYSRDGSFHFLELNPRLQVEHPCTEMIADVNL PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFDTPSNPPLPRGHVIAARITSENPDE GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDVMLGVVCGAL NVADAMFRTCMTDFLHSLERGQVLPAASLLNLVDVELIYGGIKYILKVARQSLTMFVLIM NGCHIEIDAHRLNDGGLLLSYNGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRSP SAGKLTQYTVEDGGHAEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAR LELDDPSKVHPAQPFTGELPAQPTLPILGEKLHQVFHSVLGNLTNIMSGYCLPEPIFSIK LKEWVQKLMTTLRHPSLPLLELQEIMTSVSGRIPVPVEKSVRRVMAQYASNITSVLCQFP SQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLQV EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD ELTAILHQLTQLSKTEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCP ENLKKLILSETTIFDVLPSFFYHTNKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV VEFQFMLPSSHPNRTRRPILVRWRAISSIKMAVPISVTNPDLLRHSTELFMDSGFSPLCQ RMGAMVAFQRFEDFTRNFDEVISCFANVPKDIPLFSKARTSLYSEDDYKNLREEPIHILN VAIQYADHLEDEELVPIFRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFA EDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRA IIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDP SKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTSGSAIPIRLFITNESGYYLDISLY KEVTDLRSGNIMFHSFGDKQGNLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPELF RQALFKLWGSPEKYPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVVFKMRFKTQEYPE GRDVIVISNDITFRIGSFGLGEDLLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHM FQVAWVDPEDPHKGFRYLYLTPQDYTRISALNSVHCKHIEEGGESRYVITDIIGKDDGLG VENLRGSGMIAGESSLAYEEIVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASA LNKVLGREVYTSNNQLGGVQIMHFNGVSHITVPDDFEGVYTILEWLSYMPKDNLSPVPII TPTDPIDREVEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDQGSFKEIMAPWAQTVVT GRARLGGIPVGVIAVETRTMEMAVPADPANLDSEAKITQQAGQVWFPDSAYKTAQVIKDF NREKLPLLIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYTQPILIYIPPHAELRGGSW VVLDSTINPLCIEMYADRESRGGVLEPEGTVEIKFRRKDLVKAMRRIDPAYKKLVEQLGT AQLPEKERRELEGRLRAREELLLPIYHQVAVQFADLHDTPGRMLEKGVISVSQAWVQWLE QHWQAGEGLRSAIHENIRYLRRDSALKTIRGLVQGNPDVAMDSIVYLSQHISPAERAQVA QLLSSAESPAST NT seq 7239 nt NT seq  +upstreamnt  +downstreamnt atggtcttgcttcttttcctgttttgcctgatcttctactgtctgaccttctcctggtta aaaatctgggggaaaatgacagatgcccggccagccaccaatggtcagttggaggccagc ttcaccctgagccaggaggcctctccagcctcagaccgctcggaggacaacctccaggga aacggcagcgccaccctcctgccagggacccccgacggggccgagctggccaccctcccg agccccgaaggcacccgtgggcagagaggctccagaccccccgtgcaccagaggccccca cgaaaccccgtttcttccgatggcacgtggccctccccggaacccaccgccagcgggacg gggacccagggaccaggagccccaggtaccaatggcctgtcctccccagcccggccccag ggccagccagccagggccctctccagagccgacgagaagcaggcgcacctcaagcggcag ctcctgaccagcttcatcctgggctcctttgacgacaactcctccgacgacgactctggg gccagctccttccgagagtctccccggaggggcagccgggccagcctgggtgccgcgtcc ccggactctcctcacaccgcaagtgaacctgagacctcggtccccaccatgaggccgagc atgtcggggctgcacctggtaaagaggggccgggaacacaagaagctggacgcgcacaga gacttcaccgtggcttccccggcagagtttgtcacacgctttggtggggatcgggtcatc gagaaggtgctcattgccaacaacgggatcgccgcggtcaagtgcatgcgctccatccgc aggtgggcctatgagatgttccgcaacgagcgagccatccggtttgtggtcatggtgacc cccgaggacctcaaggccaatgcagagtacatcaagatggcggaccagtacgtccccgtc cccggggggaccaacaacaacaactacgccaacgtggagctgatcgtggacattgccaag agaatccccgtgcaggccgtgtgggctggctggggccacgcctccgagaaccccaagctt ccggagctgctgtgcaagcacgggattgctttcctaggcccccccagcgaggccatgtgg gccttgggagataagatcgcttccaccatcgtggcccagaccctccagatcccaaccctg ccctggagcggaagcggcctgacggtggagtgggcagaggacgactggcagcaggggagg ccagtcagcgtccctgaggacgtgtacaaccagggctgcgtgagggacgttgacgagggc ctggaggcagcagaaaaaattggttttccagtgatgatcaaagcttctgaaggcggtgga gggaaagggatccggaaggcggagagcgcggaagactttcccatgctcttcagacaggtg cagagtgagctcccgggctcacccatctttctcatgaagctggcccagcatgcccggcac ctggaggtccaggtcctcgccgaccaatacgggaatgcggtgtcgctgtttgggcgggac tgctccatccagcggcggcatcagaagatcatcgaggaggctccggccaccattgccacg ccggccctgttggagttcatggagcagtgcgccgtccgcctggccaagaccgtgggctac gtgagcgcggggacagtcgagtacctctacagccgggacggcagcttccacttcctggag ctgaacccgcgcctgcaggtggagcatccctgcacagagatgatcgccgacgtcaacctg cccgccgcccagctgcagatcgccatgggtgtgccactgcaccggctgaaggacatccgg cttctgtatggagagtcgccgtggggcgtgacacccatatcttttgacaccccttcaaac cctcccctgcctcgaggccacgtcattgcagccagaatcaccagcgaaaacccggatgag gggtttaagccgagctctgggactgtccaggaactgaatttccgcagcagcaagaacgtg tggggttacttcagcgtggctgccacgggaggcctgcacgagtttgctgattcccagttt ggccactgcttctcctggggcgagaaccgggaagaggccatttcgaacatggtggtggct ttgaaggaactgtccatccggggggacttcaggaccaccgtggaatacctcattaacctc ttggagactgagagcttccagaacaacgacatagacactgggtggttggaccaccttatt gctgagaaagtgcaggcggagaagccggacgtcatgctcggggtggtgtgtggggccttg aacgtggctgatgcgatgttcagaacctgcatgacggatttcctgcactccctggaaagg ggccaggtcctcccagcggcttctctgctgaacctcgtggacgtggagctaatctacggg ggtatcaagtatattctcaaggtggcccggcagtctctgaccatgttcgtcctcatcatg aatggctgccacatcgagatcgacgcccaccggctgaacgacggcgggctgctgctgtcc tacaacggcaacagctacaccacgtacctgaaggaggaagtggacagttaccgaatcacc atcggcaacaagacgtgcgtgtttgagaaggagaatgatcccaccgtcctgaggtccccc tcggccgggaagctgacgcagtacacggtggaggacggcggccacgcggaggcagggagc agctacgccgagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagcggc cgagtgaagtacatcaagcggccgggagccgtgctggaagccggctgcgtggtggccagg ctggagctcgatgacccctctaaagtgcacccggcgcagcccttcacaggagagctgccc gcccagccaacactgcccatcctgggggagaagctgcaccaggtgttccacagcgtcctg gggaacctgaccaacatcatgagcggctactgcctgccagagcctatctttagcataaag ctgaaggagtgggtgcagaagctcatgacgaccctccggcacccgtcactgccactgttg gagctgcaggagatcatgaccagcgtgtcgggtcgcatccccgtccccgtggagaagtca gtccgcagggtgatggcccagtacgccagcaacatcacctccgtgctgtgccagttcccc agccagcagattgccaccatcctggactgccacgcggccaccctgcagcgcaaggctgac cgagaggtcttcttcatgaacacccagagcatcgtgcagctggttcagaggtaccgcagt gggacccgcggctatatgaaggcggtggtgctggatctcctgcgaagatatttgcaggtt gagcatcatttccaacaagctcactacgacaagtgtgtgataaacctcagggagcagttc aagccggacatgtcccaggtgctggactgcatcttctcccacgcacaggtggccaagaag aaccagctggtgatcatgctgatagatgagctctgtggcccagacccttccctgtcggac gagctgaccgccatcctccaccagctcacccagctgagcaagacggagcactgcaaagtg gccctcagagccagacaggtgctgatcgcctcccacctcccctcctacgagctgaggcac aaccaggtggagtccatcttcctgtctgccatcgacatgtatggccaccagttttgccca gaaaacctcaagaaattaatcctctcagaaacgaccatatttgatgtcctgccctccttc ttctaccacactaacaaagtcgtttgcatggcttccctggaggtctatgtgcggagaggc tacatcgcttatgagctgaacagcctgcagcacaggcagctccccgatggcacctgtgtg gtggaattccagttcatgctgccctcttcccacccaaaccggacacgacgtcccattctg gtcaggtggcgtgccatatcgtccataaagatggccgtgcccataagtgtcaccaacccc gacctgctgaggcacagcacagagctcttcatggacagtggcttctctccactgtgccag cggatgggggctatggttgccttccagagattcgaggatttcaccaggaactttgatgaa gtcatctcctgctttgccaacgtgcccaaagacatccccctcttcagcaaggcccgcacc tccctgtattcggaggacgactacaagaacctccgagaagagcccatccacatcctgaac gtggccatccagtacgcagaccatttggaggatgaggagctggtgccgattttcaggaca tttgtacagtccaagaaaaatatccttgtggattacggactccgaagaatcacattcctg atcgcccaagagaaagaatttcccaagtttttcacgttcagagcaagagatgagtttgca gaagatcgcatttaccgccacctggagcccgcgctggccttccagctggagctcagccgc atgcgtaactttgacctgacggcggtgccctgtgccaaccacaagatgcacctgtacctg ggcgctgccaaggtgaaggagggggcggaagtgacggaccacaggttcttcatccgtgcc atcatcaggcactcggacctgatcaccaaggaagcctctttcgagtacctgcagaacgag ggcgagcggctgctcctcgaggccatggatgagctggaggtggccttcaacaacaccagc gtgcgcaccgactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccc tccaagatcgaggagtcggtgcgctccatggtcatgcgctacggcagccggctgtggaag ctccgcgtgctgcaggccgaagtcaagatcaacatccgccagaccacctcgggcagcgcc attcccatccgcctgttcatcaccaacgagtcgggctactacctggacatcagcctctac aaggaagtgactgacctcagatctggaaacatcatgttccactcttttggggacaaacaa gggaacctccacgggatgctcatcaacaccccctacgtcaccaaggatctgcttcaggcc aagcgcttccaggcacagtccctggggaccacctacgtgtacgacttcccggagctgttc aggcaggctctttttaaactgtggggttccccggagaagtaccctaaagacatcctgacc tacacggaattagtgctggactctcagggccagctggtggagatgaaccggctgccaggt ggaaacgaggtgggcatggtggtcttcaaaatgaggttcaagacccaggagtatccagaa ggccgggatgtgatcgtcatcagcaacgacatcaccttccgcatcgggtcctttggcctg ggggaggatcttctctacctgagggcgtccgagatggcccgggccgagggcatccccaag atctatctggccgccaacagcggggcccgcatcggcttggctgaagagatcaaacacatg ttccaggtggcttgggtggaccccgaagacccccacaagggattcagatacctgtacctg acgccccaagactacaccagaatcagcgccctgaattccgtccactgcaaacacatcgag gagggcggggaatccaggtacgtcatcaccgacatcatcgggaaggacgacggcctgggc gtggagaacctgaggggctcgggcatgattgctggggagtcctccctggcctacgaagag atcgtcaccatcagcatggtgacctgccgcgccctcgggatcggggcctacttggtgagg ctgggccagcgggtgatccaggtggagaactcccacatcatcctcacgggggccagtgcc ctcaacaaggtgctgggaagagaggtctacacgtccaacaaccagctgggtggcgttcag atcatgcacttcaatggcgtctcccacattaccgtgccggatgactttgaaggggtctac accatcctggagtggctctcctatatgccaaaggataacctcagcccagtccctatcatc acacccactgatcctattgacagagaagttgaatttctcccgtccagagccccctacgac ccccggtggatgcttgccggaaggcctcacccaactctgaaggggacctggcagagtggc ttcttcgaccagggcagtttcaaggaaatcatggcgccctgggcccagacggtggtgacg ggtcgagccaggctgggggggatccccgtcggagtcatcgccgtggagacgcggaccatg gagatggcggtccccgcagaccctgccaaccttgattccgaggccaagatcacccagcag gcgggccaggtgtggttcccagactcggcctacaaaaccgcccaggtcatcaaggacttc aaccgcgagaagctgcctctgctgatctttgccaactggaggggcttctccgggggcatg aaagacatgtatgaccaggtgctgaagttcggggcctacatcgtggatggcctcaggcag tacacacagcccatcctcatctacatcccgccccacgcggagctgcgcgggggctcctgg gtggtcctcgactccaccatcaaccccttgtgcatagaaatgtacgcggacagagagagc agggggggcgttctggagcccgagggaacggtggagattaagttcagaagaaaagacctg gtaaaggccatgaggcgtattgacccggcttacaagaagctcgtggagcagctagggaca gcccagctcccggagaaggagcgcagggagctggagggccggctgagggcgcgcgaggag ctgctgctccccatctaccaccaggtggcggtgcagttcgccgacctccacgacacgccg ggccgcatgctggagaagggcgtcatctccgtaagccaggcgtgggtccagtggctggag cagcactggcaggcgggggaggggctgcgctccgccatccacgagaacatcaggtacctg cggcgcgactccgccctcaagaccatccgcgggctggtccaggggaaccccgacgtggcc atggacagcatcgtgtacttgagccagcacatcagcccggccgagcgggcccaggtggcc cagctgctgtcgtctgctgagagcccggcgtccacctga

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