KEGG   Marmota marmota marmota (Alpine marmot): 107157785
Entry
107157785         CDS       T09644                                 
Symbol
Grb2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma01521  EGFR tyrosine kinase inhibitor resistance
mmma01522  Endocrine resistance
mmma04010  MAPK signaling pathway
mmma04012  ErbB signaling pathway
mmma04014  Ras signaling pathway
mmma04062  Chemokine signaling pathway
mmma04068  FoxO signaling pathway
mmma04072  Phospholipase D signaling pathway
mmma04150  mTOR signaling pathway
mmma04151  PI3K-Akt signaling pathway
mmma04380  Osteoclast differentiation
mmma04510  Focal adhesion
mmma04517  IgSF CAM signaling
mmma04540  Gap junction
mmma04550  Signaling pathways regulating pluripotency of stem cells
mmma04630  JAK-STAT signaling pathway
mmma04650  Natural killer cell mediated cytotoxicity
mmma04660  T cell receptor signaling pathway
mmma04662  B cell receptor signaling pathway
mmma04664  Fc epsilon RI signaling pathway
mmma04714  Thermogenesis
mmma04722  Neurotrophin signaling pathway
mmma04910  Insulin signaling pathway
mmma04912  GnRH signaling pathway
mmma04915  Estrogen signaling pathway
mmma04917  Prolactin signaling pathway
mmma04926  Relaxin signaling pathway
mmma04935  Growth hormone synthesis, secretion and action
mmma05034  Alcoholism
mmma05160  Hepatitis C
mmma05161  Hepatitis B
mmma05163  Human cytomegalovirus infection
mmma05165  Human papillomavirus infection
mmma05200  Pathways in cancer
mmma05203  Viral carcinogenesis
mmma05205  Proteoglycans in cancer
mmma05206  MicroRNAs in cancer
mmma05207  Chemical carcinogenesis - receptor activation
mmma05208  Chemical carcinogenesis - reactive oxygen species
mmma05210  Colorectal cancer
mmma05211  Renal cell carcinoma
mmma05213  Endometrial cancer
mmma05214  Glioma
mmma05215  Prostate cancer
mmma05220  Chronic myeloid leukemia
mmma05221  Acute myeloid leukemia
mmma05223  Non-small cell lung cancer
mmma05224  Breast cancer
mmma05225  Hepatocellular carcinoma
mmma05226  Gastric cancer
mmma05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107157785 (Grb2)
   04012 ErbB signaling pathway
    107157785 (Grb2)
   04014 Ras signaling pathway
    107157785 (Grb2)
   04630 JAK-STAT signaling pathway
    107157785 (Grb2)
   04068 FoxO signaling pathway
    107157785 (Grb2)
   04072 Phospholipase D signaling pathway
    107157785 (Grb2)
   04151 PI3K-Akt signaling pathway
    107157785 (Grb2)
   04150 mTOR signaling pathway
    107157785 (Grb2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    107157785 (Grb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107157785 (Grb2)
   04540 Gap junction
    107157785 (Grb2)
   04550 Signaling pathways regulating pluripotency of stem cells
    107157785 (Grb2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    107157785 (Grb2)
   04660 T cell receptor signaling pathway
    107157785 (Grb2)
   04662 B cell receptor signaling pathway
    107157785 (Grb2)
   04664 Fc epsilon RI signaling pathway
    107157785 (Grb2)
   04062 Chemokine signaling pathway
    107157785 (Grb2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    107157785 (Grb2)
   04912 GnRH signaling pathway
    107157785 (Grb2)
   04915 Estrogen signaling pathway
    107157785 (Grb2)
   04917 Prolactin signaling pathway
    107157785 (Grb2)
   04926 Relaxin signaling pathway
    107157785 (Grb2)
   04935 Growth hormone synthesis, secretion and action
    107157785 (Grb2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    107157785 (Grb2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    107157785 (Grb2)
  09159 Environmental adaptation
   04714 Thermogenesis
    107157785 (Grb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107157785 (Grb2)
   05206 MicroRNAs in cancer
    107157785 (Grb2)
   05205 Proteoglycans in cancer
    107157785 (Grb2)
   05207 Chemical carcinogenesis - receptor activation
    107157785 (Grb2)
   05208 Chemical carcinogenesis - reactive oxygen species
    107157785 (Grb2)
   05203 Viral carcinogenesis
    107157785 (Grb2)
   05231 Choline metabolism in cancer
    107157785 (Grb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    107157785 (Grb2)
   05225 Hepatocellular carcinoma
    107157785 (Grb2)
   05226 Gastric cancer
    107157785 (Grb2)
   05214 Glioma
    107157785 (Grb2)
   05221 Acute myeloid leukemia
    107157785 (Grb2)
   05220 Chronic myeloid leukemia
    107157785 (Grb2)
   05211 Renal cell carcinoma
    107157785 (Grb2)
   05215 Prostate cancer
    107157785 (Grb2)
   05213 Endometrial cancer
    107157785 (Grb2)
   05224 Breast cancer
    107157785 (Grb2)
   05223 Non-small cell lung cancer
    107157785 (Grb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    107157785 (Grb2)
   05160 Hepatitis C
    107157785 (Grb2)
   05163 Human cytomegalovirus infection
    107157785 (Grb2)
   05165 Human papillomavirus infection
    107157785 (Grb2)
  09165 Substance dependence
   05034 Alcoholism
    107157785 (Grb2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107157785 (Grb2)
   01522 Endocrine resistance
    107157785 (Grb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmma04131]
    107157785 (Grb2)
Membrane trafficking [BR:mmma04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    107157785 (Grb2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 107157785
NCBI-ProteinID: XP_015359683
Ensembl: ENSMMMG00000010717
UniProt: A0A8C5ZE78
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccactgcagacgatgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaggatggcttcattcccaagaactacatagaaatgaaaccacacccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcatttctaatccgagagagtgagagtgctcctggggatttctccctctccgtcaag
tttggaaatgatgtgcagcacttcaaggtgctccgggacggagctggaaagtatttcctc
tgggtggtgaaattcaattctttgaatgaattggtagattaccacagatcaacatctgtg
tccagaaaccagcagatattcctgcgagacatagagcaggtgccacagcagccaacatac
gtccaggccctctttgactttgacccccaggaggacggtgagctgggcttccgccgggga
gacttcatccatgtcatggataactcagaccccaactggtggaagggggcttgccacggg
cagaccggcatgtttccccgcaattatgttacccctgtgaaccggaacgtctaa

DBGET integrated database retrieval system