Marmota marmota marmota (Alpine marmot): 107159738
Help
Entry
107159738 CDS
T09644
Symbol
Eif2ak3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma04137
Mitophagy - animal
mmma04140
Autophagy - animal
mmma04141
Protein processing in endoplasmic reticulum
mmma04210
Apoptosis
mmma04932
Non-alcoholic fatty liver disease
mmma05010
Alzheimer disease
mmma05012
Parkinson disease
mmma05014
Amyotrophic lateral sclerosis
mmma05020
Prion disease
mmma05022
Pathways of neurodegeneration - multiple diseases
mmma05160
Hepatitis C
mmma05162
Measles
mmma05168
Herpes simplex virus 1 infection
mmma05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
107159738 (Eif2ak3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
107159738 (Eif2ak3)
04137 Mitophagy - animal
107159738 (Eif2ak3)
09143 Cell growth and death
04210 Apoptosis
107159738 (Eif2ak3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
107159738 (Eif2ak3)
05162 Measles
107159738 (Eif2ak3)
05168 Herpes simplex virus 1 infection
107159738 (Eif2ak3)
09164 Neurodegenerative disease
05010 Alzheimer disease
107159738 (Eif2ak3)
05012 Parkinson disease
107159738 (Eif2ak3)
05014 Amyotrophic lateral sclerosis
107159738 (Eif2ak3)
05020 Prion disease
107159738 (Eif2ak3)
05022 Pathways of neurodegeneration - multiple diseases
107159738 (Eif2ak3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107159738 (Eif2ak3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
107159738 (Eif2ak3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107159738 (Eif2ak3)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
107159738 (Eif2ak3)
Protein kinases [BR:
mmma01001
]
Serine/threonine kinases: Other
PEK family [OT]
107159738 (Eif2ak3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
PQQ
DUF4041
Motif
Other DBs
NCBI-GeneID:
107159738
NCBI-ProteinID:
XP_015361841
Ensembl:
ENSMMMG00000009551
LinkDB
All DBs
Position
Unknown
AA seq
1097 aa
AA seq
DB search
MARAGRPGPRALLLLLLPLLLGLARPGAAGRARIPAPALGLGAAAAPTSTSAAGPGAAEV
TVEDAEALPAAAGEQDPRAPDPDAAELRPRGRSLVIISTLDGRIAALDAENHGKKQWDLD
VGSGSLVSSSLSKPEVFGNKVIIPSLDGDLFQWDRDRESMETVPFTVESLLEASYKFGDD
VVLVGGKSLTTYGLSAYSGKVRYICSALGCRRWDSDELEEEEDILLLQRTQKTVRAVGPR
SGNEKWNFSVGHFELRYIPDMETRAGFIESSFRPSGNKEESKIISDVEEQEAAMLDTVIK
VSVADWKVVAFSKKGGHLEWEYQFCTPIASAWLVRDGKVIPISLFDDTSYTSTEEVLEDE
EDIVEAARGATESSVYLGMYRGQLYLQSSVRISEKFPANPKALESVSSGNEIIPLPTIKW
KPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERSR
RSTQITVRFLDSPSYPKNVRRKDPVLLLHWWKEIVGTILFCIVATTFIVRRLFHPQPHRQ
RKESETQCQTENKYDSTSDGASASSRSDTKSSGYVSRYLTDFEPVQCLGRGGFGVVFEAR
NKVDDCDYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEEWQEKMD
AIWLKDESTDWPLSSPSLLDAPSVKIRRMDPFSSKEHIEIIAPAPRRSASFSVGISCGQT
SSSGSQFSPLEFSDMDHGNASGSEAAACSLGDRCPADRGVEGGTTGGSGRRHSFELCPSA
APTHTRSRERTSSSIVFEDSGCDNASSREEPRAERLHVSSLCAHRVATFRYSSSKSSSEA
TLSISPPRPTSLSLDLTKNTAEKLQPSSPKVYLYIQMQLCRKETLKDWLSRRCILEQRER
SACLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEPAV
LTPMPSYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFSTQMERVQTL
TEVRNLKFPPLFTQKYPREYAMVGDMLSPTPVERPEATDIIEDPVFEDLEFPGKTVLRQR
SRSLSSSGPKSPRQPSS
NT seq
3294 nt
NT seq
+upstream
nt +downstream
nt
atggcacgcgccggccgcccggggccgcgggcgctgctgctgctgctgctgccgctgctg
ctgggattggcgcggcccggagcggcgggacgcgcgcgcatccccgcgccggcgcttggc
ttgggcgccgcggccgcccccacctcgacatctgcggcggggcccggggcggccgaggtg
acggtggaggacgccgaggcgctgcccgccgccgctggggagcaggatccgcgggcgccg
gatcccgacgccgccgaactgcggccgcgcggcaggtcattagtgatcatcagtactcta
gatggacggattgccgctttggatgccgagaatcatggtaaaaagcagtgggatttggac
gtgggatccggctccctggtctcatccagcctgagtaagcctgaggtgtttgggaacaag
gtgatcatcccttccctggacggggacctcttccagtgggaccgggaccgggagagcatg
gagacggttcccttcacggtcgagtctctcctcgaagcttcttataaatttggagatgat
gttgttttggttggaggaaaatctctcacgacgtatggcctcagtgcctacagtgggaag
gtgaggtacatctgttctgccctgggttgtcgccggtgggacagcgatgagctggaggaa
gaagaggacatcctacttctgcagcgcacccagaagaccgtgagggccgtcggaccccgc
agtggcaatgagaagtggaatttcagtgttggccactttgaacttcggtatattccagac
atggaaactagagccggatttattgaaagcagctttagacccagtgggaacaaggaagag
tctaagattatttcagatgtggaagaacaggaagccgccatgctggacacggtgataaag
gtttcggtagccgactggaaggtcgtggcgttcagtaagaagggaggacacctggagtgg
gagtaccagttttgtactccgatcgcctctgcctggttggtcagagatggcaaagtcatt
ccgatcagtctctttgacgacacgagttacacgtctacagaagaggttttagaggatgag
gaggacatcgtggaagctgcacgcggggccacggagagcagcgtgtacctgggaatgtac
agaggccagctgtacctgcagtcatcagtgagaatctcagaaaagtttcctgcaaatccc
aaggccttggagtctgtcagtagtggaaatgagattattcctttgccaacaatcaaatgg
aaacccttaatccattccccttccagaacccctgtcctggtgggctctgatgaatttgac
aaatgccttagtaatgacaagttttctcacgaagagtacagcaatggtgccctttcaatc
ttgcagtatccatatgacaacgggtattacctgccctactacaagagggagcggagcagg
cggagcacgcagatcaccgtcaggttcctagacagccccagctaccccaagaatgtccgc
agaaaggacccggtgctcctcctgcactggtggaaggaaatcgtggggacgatcctgttc
tgcatcgtggccaccactttcatcgtgcgcaggctcttccaccctcagccacaccggcaa
aggaaagaatctgaaactcagtgtcaaactgaaaacaaatatgattccacaagtgacggg
gccagtgccagtagccggagtgacacaaagagctcgggatatgtatcacgctatctgacg
gattttgagccggtgcagtgcctgggccgtgggggctttggagttgtctttgaagctagg
aacaaagtagatgactgcgactatgccatcaagaggatccggctccccaacagggaactg
gctagagagaaagtaatgcgggaggtgaaggccctggccaagctagagcacccgggcatc
gtcaggtacttcaacgcctggctggaggcccccccggaggagtggcaggagaagatggac
gccatctggctcaaagacgagagcacggactggccgctcagctcgcctagcctgctggac
gcaccttccgtgaagatccgcagaatggaccctttttcctccaaagagcacattgagatc
atcgcccctgcgccccggagaagcgcgtctttctcggtggggatttcctgcggccagacc
agctcctccgggagccagttttccccactagagttctccgacatggaccacggcaacgcc
agtggatcggaagccgcggcctgcagcctcggggaccgctgccccgcagaccgtggcgtg
gagggtggcaccacagggggcagtggccgcaggcactccttcgagctgtgtccttctgcg
gcgcccacccacacgaggtccagggagaggacctcctcctccatcgtgttcgaggactct
ggctgtgacaacgcatccagcagggaggagcccagggccgagcgcctgcatgtcagcagc
ctctgtgctcaccgagtggccaccttcaggtactccagcagcaagtcgtcttccgaagcc
acgctgtccatctctcctcccagaccgacctcgctcagcttagatctcaccaagaatacg
gcggagaaactgcagcccagctccccgaaggtgtatctgtacatccagatgcagttgtgc
cggaaggagacgctcaaggactggctaagccgccgctgcatcttggagcagagagagcgg
agcgcgtgcctgcacatcttcctgcagatcgccgaggccgtggagttcctgcacagcaag
gggctcatgcacagggacctcaagccctccaacatattcttcaccatggacgatgtggtc
aaggtgggagactttgggctagtgactgcaatggaccaggatgaggaggagccggcggtt
ctgaccccgatgccatcctacgccacacacacaggacaagtggggaccaagctctacatg
agcccagagcagattcatgggaacaactactcccataaggtggacatcttctctctgggc
ctgattctgtttgaactgctgtacccattcagcactcagatggagagagtccagacctta
actgaagtaagaaatctcaagtttccaccactgttcactcagaaatatcctcgggagtac
gcgatggttggggacatgctttctccgacccccgtggaacggcccgaggccacggacatc
attgaagaccctgtgtttgaggacttggagtttccagggaagactgtgctcagacagcgg
tcacgctccctgagctcctcgggacccaagtccccgcggcagcccagcagttag
DBGET
integrated database retrieval system
