Methylomonas methanica: Metme_4450
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Entry
Metme_4450 CDS
T01511
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mmt
Methylomonas methanica
Pathway
mmt00010
Glycolysis / Gluconeogenesis
mmt00020
Citrate cycle (TCA cycle)
mmt00620
Pyruvate metabolism
mmt00785
Lipoic acid metabolism
mmt01100
Metabolic pathways
mmt01110
Biosynthesis of secondary metabolites
mmt01120
Microbial metabolism in diverse environments
mmt01200
Carbon metabolism
mmt01210
2-Oxocarboxylic acid metabolism
Module
mmt_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Metme_4450
00020 Citrate cycle (TCA cycle)
Metme_4450
00620 Pyruvate metabolism
Metme_4450
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Metme_4450
Enzymes [BR:
mmt01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Metme_4450
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AEG02793
UniProt:
G0A4Q2
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Position
4887329..4889992
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AA seq
887 aa
AA seq
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MNNNTDIAVRNDIDPAETQEWMEALQAVIEKEGSDRASFLIETLLDTARQAGLDIPFSAN
TPYINTISVDKQPKFPGNFDIERTIRSYVRWNAMMMVLRANKHTNVGGHIASFASAITLY
DVGQNHFWNAASDKHGGDLIFSQGHSAPGIYAHSFLLGRLSEEQMDNFRQEVGGNGLSSY
PHPWLMPEFWQFPTVSMGLGPIMAIYQARFMRYMQDRGFAQTDNRKVWAFLGDGESDEPE
TLGAIGMAGREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGNFRGANWNVIKVIWGRR
WDPILARDKDGLVVKRMMECVDGDYQTFKSKDGAYVREHFFNTPELKELVKDYTDRDIWE
LNRGGHDPIKVFTAFNAAVNHKGQPTVILAHTIKGYGMGDSGQAQNTSHQQKKMSMESIK
AIRDRYQLPISNEELLELPYIRLAEDSAELNYLRQRRIDLGGYLPARRTKAYPLEIPALS
AFKSLLDGGHEISTTMAFVRMLNVLVKDKQIGKRIVPIVPDESRTFGMEGMFRQLGIWSQ
VGQLYTPQDAEQLMFYKEDKHGQVLQEGINEAGGLCDWIAAGTAYSTHGVPMIPFFIYYS
MFGFQRVADLIWAAADQRTRGFLLGGTAGRTTLNGEGLQHEDGHSHLIAATVPNCYSYDP
TFAGELAVIIHDGLRRMYVEQEDIFYYITLMNENYDQAPLVEGSEADILKGMYLFKKGPN
SKKPRVQLLGSGTIFIEVIEAAKLLSEDWGVDADLWSCPSFTELARDGQSCERWNRLHPT
EKARVTHIEKCLDNAKGPIVAATDYMRAFAEQIRPWVKNPYSVLGTDGFGRSDTRANLRS
FFEVDRYHVTVAALHALAQAGEFDAGKVEVAIAKYNINPDVTAPWLI
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgaacaacaataccgacattgccgtcagaaacgatattgaccctgctgaaacccaggag
tggatggaggccctgcaggcggtgattgaaaaagaaggcagcgaccgcgccagctttctg
atcgaaacactgctcgacaccgccagacaagccggtctggacatcccgttttccgccaat
acgccttacatcaacaccatttcggtcgacaaacaacccaagtttcccggcaatttcgac
atagaacgcaccatacgttcttacgtgcgctggaacgccatgatgatggtattacgcgcg
aacaaacataccaacgtcggcggccatatcgccagtttcgcctcggccatcaccctatac
gacgtggggcaaaaccatttctggaacgcggcctccgacaaacacggcggcgacctgatt
ttctcgcaaggccattccgcgccgggcatttatgcccactcgtttttgctgggtcgcttg
agtgaagagcaaatggacaatttccgccaggaagtgggcggcaacggtttatcgtcctat
ccgcatccctggctgatgccggaattctggcaattccccaccgtatccatgggcctgggc
ccgatcatggccatttaccaagcccgtttcatgcgttacatgcaggatcgcggcttcgcc
caaacggacaaccgcaaagtctgggcctttttgggcgacggcgaatcggacgaaccggaa
accctgggcgcgatcggcatggccggccgcgaaaaactggacaacctgatcttcgtggtc
aattgcaacctgcaacgcctggacggcccggtacgcggcaacggcaaaatcattcaagaa
ctggagggcaactttcgcggcgccaactggaatgtcattaaagtgatctggggccggcgc
tgggatccgattctggcccgcgacaaggacggcctggtggtcaagcgcatgatggaatgc
gtggacggcgattaccaaaccttcaaatccaaagacggcgcttacgtccgcgagcatttt
ttcaacaccccggaactgaaggaactggttaaagattacactgaccgcgacatctgggaa
ttgaatcgcggcggccacgatcccatcaaggtcttcaccgcctttaacgctgccgtcaat
cataaaggccaaccgaccgtcattttagcccacaccatcaagggctacggcatgggcgat
tccggccaagcccaaaacaccagccatcagcaaaaaaagatgagcatggagtcgattaaa
gctatccgcgaccgctatcaactgccgatcagcaacgaggaattgctcgagctgccttac
attcgacttgccgaggactccgctgaattaaactatctgcgccagcgccgcatagacttg
ggcggttacctgccggctcgacgtaccaaagcttatccgctggaaattccggcactcagc
gccttcaaatcgctgctggacggtggccacgaaatttccaccaccatggccttcgtgcgc
atgctgaatgttttggttaaagacaaacaaatcggcaaacgcatcgtgcccatcgtgccg
gacgagtcgcgtaccttcggcatggaaggcatgtttcgccagctcggcatctggtcgcaa
gtcggccagctgtacacgccgcaagatgccgaacaactgatgttctacaaggaagacaag
cacggtcaggtgttgcaggaaggtatcaacgaagccggcggcttgtgcgactggattgcc
gcgggtactgcctactcgacccacggcgtgccgatgattccgttcttcatctattattcg
atgtttggcttccaacgtgtcgccgacctgatctgggctgcggccgaccagcgtactcgc
ggcttcctgctgggcggtaccgccggccgcacgacgctgaacggcgagggcctacagcac
gaagacggccatagccatctgatcgcggcaaccgtgcctaattgctattcttacgacccg
acctttgccggcgaattggcggtgattatccacgacggtttgcggcgcatgtacgtggaa
caggaagatattttctattacatcacgctgatgaacgaaaactacgaccaagccccactg
gtggaaggttcggaagccgacatactgaaaggcatgtatctgttcaaaaaaggcccgaac
agcaaaaagccccgcgtgcaattgctgggctccggcaccatctttatcgaagtgatcgaa
gccgccaagctgctgagcgaagactggggggtggacgccgacctgtggagctgcccgagt
tttaccgaactggcccgcgacggtcaaagctgcgagcgttggaaccgattgcatcccacc
gagaaagcccgcgttacgcatatcgaaaagtgcctggacaacgccaaaggtcctatcgtt
gccgccaccgattatatgcgcgccttcgccgagcaaatccggccttgggtgaaaaaccct
tactccgtgttgggcaccgacggtttcggccgttcagacacccgcgccaacttgcgcagt
ttctttgaagtggacagataccacgtcactgtggccgccctacacgctctggcgcaagcc
ggcgaattcgatgccggcaaagtcgaagtggcaattgctaaatacaatatcaatccggac
gtcaccgcgccgtggttgatttaa
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