Mus musculus (house mouse): 100705
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Entry
100705 CDS
T01002
Symbol
Acacb, Acc2, Accb
Name
(RefSeq) acetyl-Coenzyme A carboxylase beta
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00061
Fatty acid biosynthesis
mmu00620
Pyruvate metabolism
mmu00640
Propanoate metabolism
mmu01100
Metabolic pathways
mmu04152
AMPK signaling pathway
mmu04910
Insulin signaling pathway
mmu04920
Adipocytokine signaling pathway
mmu04922
Glucagon signaling pathway
mmu04931
Insulin resistance
mmu04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100705 (Acacb)
00640 Propanoate metabolism
100705 (Acacb)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100705 (Acacb)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100705 (Acacb)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100705 (Acacb)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100705 (Acacb)
04922 Glucagon signaling pathway
100705 (Acacb)
04920 Adipocytokine signaling pathway
100705 (Acacb)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100705 (Acacb)
04931 Insulin resistance
100705 (Acacb)
Enzymes [BR:
mmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100705 (Acacb)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100705 (Acacb)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100705 (Acacb)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
COMMD8_HN
BSH_YknX
Motif
Other DBs
NCBI-GeneID:
100705
NCBI-ProteinID:
NP_598665
MGI:
2140940
Ensembl:
ENSMUSG00000042010
UniProt:
E9Q4Z2
Q3UHC8
Q9ESZ3
LinkDB
All DBs
Position
5:114284748..114388822
Genome browser
AA seq
2448 aa
AA seq
DB search
MVLLLFLTCLVFSCLTFSWLKIWGKMTDSKPLTNSKVEANLLSSEESLSASELSGEQLQE
HGDHSCLSYRGPRDASQQRNSLPSSCQRPPRNPLSSNDTWPSPELQTNWTAAPGPEVPDA
NGLSFPARPPSQRTVSPSREDRKQAHIKRQLMTSFILGSLDDNSSDEDPSAGSFQNSSRK
SSRASLGTLSQEAALNTSDPESHAPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEF
VTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEY
IKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHEIA
FLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRHQGKCISVPEDVYE
QGCVKDVDEGLQAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIF
LMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQC
AVLLAKMVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMG
VPLHRLKDIRLLYGESPWGVTPIPFETPLSPPIARGHVIAARITSENPDEGFKPSSGTVQ
ELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDF
RTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAEKPDIMLGVVCGALNVADAMFRTC
MTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYALKVARQSLTMFVLIMNGCHIEIDAH
RLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTV
EDGDHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGVILEAGCVVARLELDDPSKVH
AAQPFTGELPAQQTLPILGEKLHQVFHGVLENLTNVMSGYCLPEPFFSMKLKDWVQKLMM
TLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDC
HAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLNVEHHFQQAHYD
KCVINLREQFKPDMTQVLDCIFSHSQVAKKNQLVTMLIDELCGPDPTLSDELTSILCELT
QLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSE
TTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSS
HPNRMAVPISVSNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFA
NVQTDTLLFSKACTSLYSEEDSKSLREEPIHILNVAIQCADHMEDEALVPVFRAFVQSKK
HILVDYGLRRITFLVAQEREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDL
TAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLL
EAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPLKIEESVRDMVMRYGSRLWKLRVLQA
EVKINIRQTTSDSAIPIRLFITNESGYYLDISLYREVTDSRSGNIMFHSFGNKQGSLHGM
LINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYPKDILTYTELVL
DSQGQLVEMNRLPGCNEVGMVAFKMRFKTPEYPEGRDAVVIGNDITFQIGSFGIGEDFLY
LRASEMARTEGIPQIYLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLTPQDYT
QISSQNSVHCKHIEDEGESRYVIVDVIGKDANLGVENLRGSGMIAGEASLAYEKTVTISM
VTCRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNG
VSHVTVPDDFEGVCTILEWLSFIPKDNRSPVPITTPSDPIDREIEFTPTKAPYDPRWMLA
GRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPA
DPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNKERLPLMIFANWRGFSGGMKDMYEQ
MLKFGAYIVDGLRLYEQPILIYIPPCAELRGGSWVVLDSTINPLCIEMYADKESRGGVLE
PEGTVEIKFRKKDLVKTIRRIDPVCKKLVGQLGKAQLPDKDRKELEGQLKAREELLLPIY
HQVAVQFADLHDTPGHMLEKGIISDVLEWKTARTFFYWRLRRLLLEAQVKQEILRASPEL
NHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSAKDGLRSTIRENINYLKRDS
VLKTIQSLVQEHPEVIMDCVAYLSQHLTPAERIQVAQLLSTTESPASS
NT seq
7347 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgcttctctttctgacttgcctggttttctcctgcctgaccttttcctggcta
aaaatctgggggaagatgacagactcgaagccgctcaccaacagtaaggtggaagccaat
ctcctttcaagcgaggagtccctttcagcctcagagctgtcaggggaacagctgcaggaa
catggcgaccacagctgtctgtcctacagaggtcccagagacgccagtcagcagaggaac
tccctgccaagctcatgccagaggcctccgaggaacccactgtcttccaatgacacctgg
ccctccccagaactccaaaccaactggacagccgccccgggcccagaggttccagatgct
aatgggttgtccttcccagccaggcccccgagccagaggacagtatccccctccagagag
gacaggaagcaggcacacatcaagagacagctgatgaccagctttatcctgggctccctg
gatgacaactcctctgatgaggaccctagtgccggctccttccagaactcctcccggaag
agcagcagggctagcctgggcactctgtcccaggaggctgcattgaacacaagtgatcct
gaatctcacgcgcctactatgaggcccagcatgtctggactccatctggtgaagagaggc
cgagaacacaagaaactggacctgcacagagatttcaccgtcgcgtccccagccgagttt
gtcactcggtttggaggcaacagggtcatagagaaggtgctcatcgccaacaatggcatc
gctgcggtcaagtgtatgcgctccatccgccgctgggcctacgagatgttccgtaatgaa
cgtgccatccggttcgtggtcatggtgacgcccgaggatctgaaggccaacgcagagtac
atcaagatggccgatcagtacgtccctgtcccaggaggacccaataacaacaactatgcc
aatgttgagctgatcatagacattgccaagagaatccctgtacaggccgtgtgggctggc
tggggccacgcttcggaaaaccccaaacttccagagctgctgtgtaaacacgagattgct
ttcctaggtccccccagtgaggccatgtgggccctgggagacaagatcgcctccaccatc
gtagcgcagacactgcaaatcccaaccttaccctggagtggaagcggtctcacagtggag
tggacggaggacagccggcaccagggcaaatgcatcagtgtccccgaagacgtttacgag
cagggctgtgtgaaggatgtggacgaaggcttgcaggcagcagaaaaaataggatttcct
ttgatgatcaaagcctccgaaggcggaggcgggaaaggtatccgcaaggctgagagtgca
gaggacttcccgatgcttttccgacaagtgcagagtgagattccgggctcgccgatcttt
ctaatgaagctggcccagaacgcacggcacctggaggtccaggtcttggcagatcagtat
ggaaacgcggtgtcactgttcggacgggactgttccattcagaggcggcaccagaagatc
attgaggaggctccggccaccatcgccgcgcctgccgtgtttgagttcatggaacagtgt
gctgtcctcctggccaagatggtgggttatgtgagcgcggggactgtggagtacttatac
agccaggatggcagcttccacttcctggagctgaacccacgcctgcaggtggagcatccg
tgcactgaaatgatcgcagatgtcaacctgcctgctgcgcagttgcagatcgccatgggc
gtgcccctgcaccgactgaaggacatacggcttctgtacggagagtccccctggggagtg
acccccattccttttgaaacccccttgagccctcccattgcccgaggccacgtcattgca
gccaggatcaccagcgaaaacccagatgagggctttaagccaagctcggggacagtgcag
gagctgaacttccgcagcaacaagaacgtgtggggttacttcagcgtggccgctgctggg
ggcttgcacgagttcgccgattcccagtttgggcactgcttctcctggggcgagaaccgt
gaagaggccatttcgaacatggtagtggctttgaaggaactgtccatccggggtgacttc
cggaccactgtggagtatctcgttaaccttctggagaccgagagcttccagaacaacgat
atcgacacggggtggctggaccacctcatcgctcagcgggtgcaggcagagaagccggac
atcatgcttggggtggtgtgtggggccttgaatgtggcagacgcgatgttcagaacctgc
atgacggaattcttgcactccctggaaaggggtcaggtcctccctgctgattctctgctg
aacattgtggacgttgaattgatttacggcggcatcaagtatgctctcaaggtagcccga
cagtccctgactatgtttgtcctcatcatgaacggctgccacatcgagatcgatgcccac
cggctgaacgatggggggctgctcctgtcctacaatggcagcagttacactacgtacatg
aaggaagaggttgacagttaccggatcactatcggcaataagacttgcgtgtttgaaaag
gaaaacgaccccactgtcctgagatccccctcggctgggaagctgatgcagtatacggtg
gaggacggagaccacgtggaagctgggagcagctacgcggagatggaggtgatgaagatg
atcatgaccctgaacgtgcaggagagcggccgggtgaagtacatcaagcggccaggggtt
atactggaggctggctgcgtggtggcgaggctagaactcgatgacccttcaaaagtgcac
gcggcccagccgtttactggggagctccctgcccagcagactctgcccatcctcggggag
aagctacaccaagtgttccacggcgtcttggaaaatctgaccaatgtcatgagtggctac
tgcctgcccgagcccttcttcagcatgaagctgaaggactgggtccagaagctcatgatg
acgctccggcatccctccctacctctgctggagctacaggagatcatgaccagtgtggcc
ggccgcatccccgccccggtggagaaggcagtccgcagggtgatggcccagtacgccagt
aacatcacctccgtgctatgccagttccccagccagcagatagccaccatcctggactgc
catgccgccaccctgcagcgtaaggcggaccgagaggtcttcttcatgaacacacagagc
atcgtgcagctggtccagagataccgcagcgggacccgtggctacatgaaggctgtggtg
ctggacctcctgaggaaatatctaaacgtggagcaccattttcagcaagcccactatgac
aagtgtgtgatcaacctgagggagcagttcaagccggacatgacccaggtgctggactgc
atcttctcacactcccaggtggccaagaagaaccagctggtgaccatgctgatagatgag
ctgtgcggcccagaccccaccctgtcagacgagctgacctccatcctctgtgagctcacg
cagctgagcagaagcgagcactgcaaggttgccctcagagccagacaggtcctgatcgcc
tcccacctcccctcctacgagctgcggcacaaccaggtggagtccatcttcctgtccgcc
atcgacatgtacggccaccagttctgcccagaaaatctcaagaaactaatactttcagaa
acgaccatattcgacgtcctgcccactttcttctatcacgagaacaaggttgtctgtatg
gcgtccctggaggtttacgtgcggagaggctacatcgcctacgagctaaacagcctgcag
caccgggagctcccagatggcacctgtgtggtggagttccagttcatgctgccctcttcc
caccccaaccggatggccgtgcccatcagtgtctccaaccccgacctgctgaggcacagc
acagaactcttcatggacagtggcttctccccactgtgccagcggatgggggccatggtg
gccttcaggagatttgaagaattcaccaggaactttgatgaagtcatctcctgctttgcc
aacgtgcagacagacactcttctcttcagtaaggcgtgcacttccctgtactcagaggaa
gacagcaagagcctccgagaggaacccatccacatcctgaatgtggccatccagtgtgcc
gaccacatggaggacgaggcgctggtgccagtcttccgtgcctttgtacagtccaagaag
cacatccttgtggattacggactccgaagaatcacattccttgttgcccaagagagagaa
ttccccaagttcttcacgttcagagcgagggatgagtttgcagaagaccggatttatcgc
cacttggagcctgccctggccttccagctggagctgagccggatgcgcaactttgacctg
accgctgtgccctgtgccaaccacaagatgcatctttacctgggagccgctaaggtgaag
gaagggttggaggtgaccgaccacaggttctttatccgagccattatccggcactcagac
ctgatcaccaaggaagcctccttcgagtacctgcagaacgaaggtgagcggctgctgctg
gaagccatggacgagctggaggtggcgttcaacaacaccagtgtgcgcactgactgcaac
cacatcttcctcaactttgtgcccacagtcatcatggacccgctcaagatcgaggagtcg
gtgcgtgacatggtcatgcgctatggcagccgtctgtggaagctccgagtgctgcaggcc
gaggttaagatcaacatccgtcagacaacctcagatagtgccatccccatccgcctcttc
atcaccaacgagtctggctactacctggacatcagcctctatagagaagtgacggactcc
agatccggaaatatcatgtttcattcctttggcaacaagcaaggtagcctgcatgggatg
ctgatcaatacaccctatgtcaccaaggacctgctccaggctaagcgattccaggcacag
tccctcgggaccacctatgtgtacgacttcccagagatgttcaggcaggctctctttaaa
ctgtggggctccccagagaagtaccccaaagatatcctgacatacacagagctggtgttg
gactctcaaggtcagctggtggagatgaaccggcttcctggttgtaacgaggtgggcatg
gtggccttcaaaatgaggttcaagaccccggagtatccagaaggccgggacgccgttgtc
atcggcaatgacatcaccttccaaatcggctctttcggcataggggaggacttcctgtac
ctgcgagcgtctgagatggcccggacagagggcatcccccaaatctacctggcagctaac
agcggggcccgtatgggcctggctgaggagatcaaacagatattccaagtggcttgggtg
gacccagaggatccccacaaaggatttagatacctgtacctgacgccccaagactacacc
cagatcagttcccagaactcagtgcactgcaagcacatcgaagatgaaggcgaatccaga
tacgtcatcgtggatgtcatcgggaaggatgccaacctgggtgtggagaacctgaggggc
tcgggcatgattgcaggagaagcttccctggcttatgagaaaacggtcaccatcagcatg
gtgacctgccgcgcccttggaatcggggcttacctggtgaggcttggccagcgggtgatc
caggtggaaaactcccacatcatcctcaccggagccggtgctctcaacaaggtcctggga
agagaggtctacacgtccaacaaccagctaggtggcgtgcagatcatgcataccaacggg
gtctcccacgtcaccgtgccagatgacttcgagggggtctgcaccattctggaatggctg
tcatttataccgaaggacaatcgcagcccggtccccatcaccactccttctgaccccatc
gacagggaaattgaattcaccccaaccaaagctccctacgaccccaggtggatgcttgca
ggcaggcctcacccaactctgaaggggacctggcagagtggattcttcgaccatggcagt
ttcaaggaaatcatggcaccctgggcccagactgtggtgacgggacgagcaaggctgggg
ggcatccctgtgggagtgattgctgtggagactcggactgtggaggtggctgtccccgct
gaccctgccaacttggattctgaggccaagatcatccagcaggcgggccaggtgtggttc
ccggactcggcctacaagacggcgcaggtcatcagggacttcaacaaggagcgcctgcct
ctcatgatcttcgccaactggaggggcttctccggaggcatgaaggacatgtatgagcag
atgctgaagtttggcgcctacatcgtggatggtctccgcctgtacgagcagcccattctc
atctacatccctccctgtgcggagctccgtgggggctcctgggttgtcctggactccacc
atcaaccccctgtgcatagagatgtatgcagacaaagagagcagggggggtgttctggag
ccggagggcacggtggagattaagttccggaagaaagatctggtgaaaaccataaggagg
atagacccagtgtgtaagaagctcgtgggacagctggggaaagcccagcttcccgacaag
gaccggaaggagctggagggccagctgaaggcccgggaggaactgctgcttcccatctac
caccaggtggcagtgcagttcgcagacctgcacgacaccccgggccacatgctggagaaa
ggaatcatttctgatgtgctggaatggaagactgcccgcaccttcttctactggaggctg
cgccggctgctgctggaggcccaggtgaagcaggagatactccgagccagccccgagctg
aaccacgagcacacacagtccatgctgcgacgctggttcgtggagactgagggcgctgtc
aaggcctacctgtgggacagcaaccaggtggtggtccagtggctggaacagcactggtca
gccaaggacggcttgcgctccaccatccgtgaaaacatcaattatctgaagcgggactct
gtcctcaagaccatccaaagtctggtccaagaacatccagaggtcatcatggactgcgtg
gcctacctgagccagcacctcacgccagccgagcggatacaggtggctcagctgctgtct
accacggagagcccagcttcctcctga
DBGET
integrated database retrieval system
