Mus musculus (house mouse): 11514 Help Entry 11514             CDS       T01002                                  Symbol Adcy8, AC8 Name (RefSeq) adenylate cyclase 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism mmu  Mus musculus (house mouse) Pathway mmu00230   Purine metabolism mmu01100   Metabolic pathways mmu01522   Endocrine resistance mmu04015   Rap1 signaling pathway mmu04020   Calcium signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04072   Phospholipase D signaling pathway mmu04081   Hormone signaling mmu04082   Neuroactive ligand signaling mmu04114   Oocyte meiosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04261   Adrenergic signaling in cardiomyocytes mmu04270   Vascular smooth muscle contraction mmu04371   Apelin signaling pathway mmu04540   Gap junction mmu04611   Platelet activation mmu04713   Circadian entrainment mmu04714   Thermogenesis mmu04720   Long-term potentiation mmu04723   Retrograde endocannabinoid signaling mmu04724   Glutamatergic synapse mmu04725   Cholinergic synapse mmu04727   GABAergic synapse mmu04742   Taste transduction mmu04750   Inflammatory mediator regulation of TRP channels mmu04911   Insulin secretion mmu04912   GnRH signaling pathway mmu04913   Ovarian steroidogenesis mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04916   Melanogenesis mmu04918   Thyroid hormone synthesis mmu04921   Oxytocin signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04925   Aldosterone synthesis and secretion mmu04926   Relaxin signaling pathway mmu04927   Cortisol synthesis and secretion mmu04928   Parathyroid hormone synthesis, secretion and action mmu04934   Cushing syndrome mmu04935   Growth hormone synthesis, secretion and action mmu04970   Salivary secretion mmu04971   Gastric acid secretion mmu04972   Pancreatic secretion mmu04976   Bile secretion mmu05032   Morphine addiction mmu05163   Human cytomegalovirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05200   Pathways in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     11514 (Adcy8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     11514 (Adcy8)    04371 Apelin signaling pathway     11514 (Adcy8)    04020 Calcium signaling pathway     11514 (Adcy8)    04072 Phospholipase D signaling pathway     11514 (Adcy8)    04024 cAMP signaling pathway     11514 (Adcy8)    04022 cGMP-PKG signaling pathway     11514 (Adcy8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     11514 (Adcy8)    04081 Hormone signaling     11514 (Adcy8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     11514 (Adcy8)   09144 Cellular community - eukaryotes    04540 Gap junction     11514 (Adcy8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     11514 (Adcy8)    04062 Chemokine signaling pathway     11514 (Adcy8)   09152 Endocrine system    04911 Insulin secretion     11514 (Adcy8)    04923 Regulation of lipolysis in adipocytes     11514 (Adcy8)    04912 GnRH signaling pathway     11514 (Adcy8)    04913 Ovarian steroidogenesis     11514 (Adcy8)    04915 Estrogen signaling pathway     11514 (Adcy8)    04914 Progesterone-mediated oocyte maturation     11514 (Adcy8)    04921 Oxytocin signaling pathway     11514 (Adcy8)    04926 Relaxin signaling pathway     11514 (Adcy8)    04935 Growth hormone synthesis, secretion and action     11514 (Adcy8)    04918 Thyroid hormone synthesis     11514 (Adcy8)    04928 Parathyroid hormone synthesis, secretion and action     11514 (Adcy8)    04916 Melanogenesis     11514 (Adcy8)    04925 Aldosterone synthesis and secretion     11514 (Adcy8)    04927 Cortisol synthesis and secretion     11514 (Adcy8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     11514 (Adcy8)    04270 Vascular smooth muscle contraction     11514 (Adcy8)   09154 Digestive system    04970 Salivary secretion     11514 (Adcy8)    04971 Gastric acid secretion     11514 (Adcy8)    04972 Pancreatic secretion     11514 (Adcy8)    04976 Bile secretion     11514 (Adcy8)   09156 Nervous system    04724 Glutamatergic synapse     11514 (Adcy8)    04727 GABAergic synapse     11514 (Adcy8)    04725 Cholinergic synapse     11514 (Adcy8)    04720 Long-term potentiation     11514 (Adcy8)    04723 Retrograde endocannabinoid signaling     11514 (Adcy8)   09157 Sensory system    04742 Taste transduction     11514 (Adcy8)    04750 Inflammatory mediator regulation of TRP channels     11514 (Adcy8)   09149 Aging    04211 Longevity regulating pathway     11514 (Adcy8)    04213 Longevity regulating pathway - multiple species     11514 (Adcy8)   09159 Environmental adaptation    04713 Circadian entrainment     11514 (Adcy8)    04714 Thermogenesis     11514 (Adcy8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     11514 (Adcy8)    05207 Chemical carcinogenesis - receptor activation     11514 (Adcy8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     11514 (Adcy8)    05163 Human cytomegalovirus infection     11514 (Adcy8)   09165 Substance dependence    05032 Morphine addiction     11514 (Adcy8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     11514 (Adcy8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     11514 (Adcy8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     11514 (Adcy8) Enzymes [BR:mmu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      11514 (Adcy8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  11514 NCBI-ProteinID:  NP_033753 MGI:  1341110 Ensembl:  ENSMUSG00000022376 UniProt:  P97490 Q3UUN2 LinkDB All DBs Position 15:complement(64570884..64794145) Genome browser AA seq 1249 aa AA seqDB search MELSDVHCLSGSEELYTIQPTPPAGDDGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG GVSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGPGERAHNTGGTKVFPERSGSGSASGSG GGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSE VVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDNTSHTYL QYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLL QVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLR LETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKG FTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCC VEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLES GGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLCLPEDIV KESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQS GPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIV LLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETY LARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVL AMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASL LLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARH FLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELL GEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSF NNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKD QGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQS LNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP NT seq 3750 nt NT seq  +upstreamnt  +downstreamnt atggagctctcggatgtgcactgccttagtggcagcgaggaactctacaccatccaaccg acgcccccggccggcgacgacgggagcggctctcggccgcagcggctgctgtggcagacg gcggtgcggcacatcacggagcagcgcttcatccacgggcaccgaggcggcggcggcggc ggggtctcccgcaaagcctcgaaccctgcgggcagtggacccaatcaccacgcgccgcag ctgtctagcgactcggtgctgcctctctattctctgggccccggagagcgagcgcacaac accggtggcaccaaagtctttccggaacgcagcgggagcggcagtgccagtggcagcggg ggcgggggcgacttgggcttcctacaccttgactgtgccccaagtaactcggatttcttc ctcaatggaggatacagctaccgaggggtcatttttccaaccctacgcaactccttcaag tctcgggatctggagcgcctctaccaacgctatttcctgggccagaggcgcaaatcggag gtagtgatgaacgtgttggatgtactaaccaaactcacccttttagtcctgcacttgagc ctggcctcggctccaatggaccctctcaagggcatcctgctaggctttttcactggcatc gaggtggtgatctgcgccctcgtggtggtcaggaaggacaacacctcccacacttacctg caatacagcggcgtggtcacttgggtggctatgaccacccagattctggcagcaggcctg ggctatgggcttctgggcgacggcataggctacgtgctttttacactcttcgccacctac agcatgcttcccctgcctctcacctgggccatcttggccggcctgggcacatctttgctg caagtcacccttcaagtactcatacccaggctagcggtcttttccatcaaccaggtcctg gcccaggtggtgctattcatgtgtatgaatacagcaggaatcttcatcagttacctttca gaccgtgcccagcgccaggccttcctggagacccggaggtgtgtggaggccaggctccgc ttggagacagagaaccaaagacaggagcggcttgtgctgtctgtgctccccaggtttgtc gtcctggaaatgatcaacgacatgaccaatgtggaggatgagcacctgcagcatcagttc caccgcatctacatccatcgctatgagaacgtcagtattctttttgcagatgtcaaagga tttaccaacctctctacgaccttgtctgctcaggagctggtcaggatgctcaacgaactc tttgccagattcgaccggctggcccatgagcatcactgtcttcgcattaaaatcctgggg gactgctactactgtgtgtctggactgcctgagccccgccgggaccacgctcattgctgt gttgaaatgggcctcagcatgatcaaaactatcaggtttgtgagatccagaacgaagcac gatgttgacatgcgaattggaatccattcaggttctgtgctatgtggtgtgttgggcctg aggaaatggcagtttgatgtctggtcttgggatgtggacatagcaaacaagcttgagtct ggaggaatccctgggaggattcacatttctaaagccaccctggattgcctcaatggtgac tataacgtggaagagggtcacgggaaagagaggaacgaattcttgaggaagcataacata gagacctatttgattaagcagcctgaggagagtttgctctgcttgcctgaagacatcgtt aaggagtcggtgagctgctctgacaggagaaacagtggagcaacattcacagaaggatcg tggagcccagagctgcctttcgacaacatcgtgggcaaacagaatactctggctgcccta acaagaaattcaataaatctgcttccaaaccatctcgcacaagctttgcatgtccagtct gggcctgaggaaattaacaagagaatagagcataccatcgacttgcggagtggcgataag ttgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctggagcac aagtattctcaaatgagggatgaagtattcaagtcaaacttggtctgtgcatttatcgtt cttctgtttatcactgcaattcaaagtttgcttccttcttcaaggctgatgcctatgact atccagttctccatcctgatcatgctgcactctgccctggtcctcatcaccacagcagaa gactataagtgtctgcccctcatcctccgaaaaacctgctgttggattaatgagacctat ctggcccgcaacgtcatcatcttcgcttccatcttaattaacttcctgggagctgtccta aatattctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcc tcagctgtgtttacagatatctgctcctacccagagtactttgtcttcactggggtgttg gccatggtgacctgtgctgtgtttctacggcttaactctgtcctgaagctggcagtgcta ctcatcatgatcgccatctacgccctgctcacagagaccatctacgcaggtctctttctg agttatgacaacctgaaccacagtggagaagatttcctggggaccaaggaagcatcactg ctgctgatggccatgttccttcttgctgtgttctaccatggacaacagctggagtacaca gcccgcctggatttcctgtggcgcgtacaggccaaagaggagatcaacgagatgaaggaa ctgagggaacacaacgagaacatgctgcgcaatatcttacccagccatgtggcccgccac ttcctggagaaagacagagacaatgaggagctgtattctcaatcctacgatgctgttgga gtgatgttcgcctccatccctgggttcgcagacttctactctcagacagaaatgaacaac cagggagtagaatgtctgcgcttgctgaatgagatcattgctgactttgatgagctgctc ggggaggaccggtttcaggacattgagaagattaagaccattggtagtacatacatggct gtctcaggactgtccccagagaaacagcaatgtgaagataaatggggacatttgtgtgcc ctggctgacttctctcttgctctgactgaaagcatacaagagatcaacaagcattcattc aacaattttgaactccgaatcggcatcagccatggctcagtggtggcaggtgtaattgga gctaagaaaccacagtatgacatttgggggaaaactgtgaacttggcaagccgaatggac agcacgggagtaagtggccggatccaagttcctgaggagacctaccttatcctgaaggac cagggctttgcctttgactaccgtggggagatatatgtgaagggcatcagtgaacaagaa gggaaaatcaaaacatactttctcctgggacgagtccaacccaacccattcatcttaccc ccaaggagacttcccgggcaatactctctggctgcggttgtccttggccttgtccagtct ctcaacaggcaaaggcagaagcaacttctcaacgagaacagcaattcgggcatcatcaag agccattacaaccggcggactttgctaacgccaagtgggccagagcctggagcacaagct gaaggcactgacaaatccgatttgccataa

DBGET integrated database retrieval system