Mus musculus (house mouse): 11684
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Entry
11684 CDS
T01002
Symbol
Alox12, 9930022G08Rik, Alox12p, P-12LO
Name
(RefSeq) arachidonate 12-lipoxygenase
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00590
Arachidonic acid metabolism
mmu01100
Metabolic pathways
mmu04726
Serotonergic synapse
mmu04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
11684 (Alox12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
11684 (Alox12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
11684 (Alox12)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
11684 (Alox12)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
11684
NCBI-ProteinID:
NP_031466
MGI:
87998
Ensembl:
ENSMUSG00000000320
UniProt:
P39655
A2CF85
LinkDB
All DBs
Position
11:complement(70132283..70146206)
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AA seq
663 aa
AA seq
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MGRYRVRVVTGAWLFSGSLNLVRLWLVGEHREAKLELQLRPARGKEEEFDFDVPEDLGPL
QFVKLHKQHTVVDDAWFCNLITVQGPGTSAEAVFPCYRWVQGEGILSLPEGTARLAGDNA
LDVFQKYREKELKERQQTYCWATWKEGLPQTIAADCKDDLPPNMRFHEEKRLDFEWTLKA
GVLEMGLKRVYTLLRSWNHLEDFDQIFWGQKSALAEKVHQCWQEDELFGYQFLNGANPML
LRRSTSLPSRLVLPSGMEELQAQLEKELKNGSLFEADFILLDGIPANVIRGEPQYLAAPL
VMLRMDPGGKLLPMAIQIQPPNPSSPAPTLFLPSDPPLAWLLAKIWVRNSDFQLQELQFH
LLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGIFDQVVST
GGGGHVQLLTRAVAQLTYHSLCPPDDLANRGLLRIPSALYARDALQLWEVTARYVKGMVH
LFYQSDDIVRGDPELQAWCREITEVGLCHAQDRGFPVSFQSRAQLCHFLTMCVFTCTAQH
AAINQGQLDWYGWVPNAPCTMRMPPPTSKDDVTMETVMGSLPDVQKACLQMTITWHLGRL
QPDMVPLGHHTEKYFSDPRTKAVLSQFQADLDNLEKEITARNEQLDLPYEYLKPSRIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcgtccgtgtggtcactggggcctggctcttctccggatccctcaac
ctagtgcgtttgtggctggttggggagcaccgggaggcgaaactggagctgcaactgcgg
ccagcgcggggcaaggaggaggagtttgacttcgacgttcccgaggacttggggccactg
cagtttgtgaaactgcacaaacagcacacagttgtggatgacgcctggttctgcaacctc
atcacagttcaggggccggggacaagtgcagaggccgtgtttccctgctaccgctgggtg
cagggagagggaatcctgagcctcccggaggggacagcccgcctggcaggagacaatgcc
ttagatgtcttccagaagtatcgagaaaaggaactgaaggaaagacaacagacctactgc
tgggccacctggaaagaaggcttacctcagacaatagcagcggactgtaaggatgacctt
cctccaaatatgagattccatgaggagaagagactggactttgaatggacgttgaaggcg
ggggttctggaaatgggcctcaaacgtgtttataccctcctgagaagctggaaccatctg
gaagactttgatcagatcttctggggccagaagagtgccttggccgagaaggttcaccag
tgttggcaggaagatgaactctttggctaccagttcctcaatggcgccaaccccatgctt
ttgagacgctccacctctctgccctccagactggtactgccctctgggatggaggagctt
caagctcagttggagaaagaactcaagaatggatccctgtttgaagctgactttatcctg
ctggatggaattccagctaatgtgatccgaggagaaccacagtacctggctgcccctctt
gtcatgctgaggatggaccccggtgggaagctgctacccatggctatccagattcagccc
cctaaccccagctccccagctccaacactgttcctgccctcggatcctccacttgcctgg
ctcttggctaagatctgggtccgaaattcagatttccaactgcaggagctccaattccat
ttgctgaacacccatctggtggctgaggtcatcgctgttgccaccatgagatgcctccca
ggactgcaccctatcttcaagctcctcgttccacacatccgttacactatggaaattaac
acgcgaagccggacccagctcatctcagatggaggaatatttgatcaggtagtgagcaca
ggtggaggcggccatgttcagttgcttactcgggcagtggctcagctgacttaccactcc
ctctgtcctcctgatgatctggctaaccgaggcctgctgagaatcccaagtgctctctat
gctcgggatgctttacagctctgggaagtcactgccaggtatgtgaaggggatggtccat
ctcttctaccagagtgatgatattgtgaggggagacccagagctgcaggcctggtgtcgg
gagatcactgaagtggggctgtgccatgcccaggacagaggattccctgtctccttccag
tcccgggctcagctctgccatttcctcaccatgtgtgttttcacatgcactgcccagcat
gctgccatcaaccagggccagctggactggtatggttgggtacctaatgctccatgcaca
atgaggatgcctccgcccaccagcaaggacgacgtgacgatggagaccgtgatggggtcg
ctacctgatgtgcagaaggcctgtcttcagatgactatcacatggcacctgggtcgcctg
cagccagacatggtacctctaggacaccacacagaaaaatatttctcagacccaaggacc
aaagctgtgctcagccaatttcaagcagatttggacaatttggagaaagagattacagcc
cggaatgagcaacttgacctgccttatgaatacctcaagcccagccgcatagagaacagt
atcaccatctga
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