Mus musculus (house mouse): 11783
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Entry
11783 CDS
T01002
Symbol
Apaf1, 6230400I06Rik, Apaf-1, Apaf1l, fog, mKIAA0413
Name
(RefSeq) apoptotic peptidase activating factor 1
KO
K02084
apoptotic protease-activating factor
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01524
Platinum drug resistance
mmu04115
p53 signaling pathway
mmu04210
Apoptosis
mmu04215
Apoptosis - multiple species
mmu05010
Alzheimer disease
mmu05012
Parkinson disease
mmu05014
Amyotrophic lateral sclerosis
mmu05016
Huntington disease
mmu05020
Prion disease
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05134
Legionellosis
mmu05152
Tuberculosis
mmu05160
Hepatitis C
mmu05161
Hepatitis B
mmu05162
Measles
mmu05164
Influenza A
mmu05168
Herpes simplex virus 1 infection
mmu05169
Epstein-Barr virus infection
mmu05200
Pathways in cancer
mmu05222
Small cell lung cancer
mmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
11783 (Apaf1)
04215 Apoptosis - multiple species
11783 (Apaf1)
04115 p53 signaling pathway
11783 (Apaf1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
11783 (Apaf1)
09162 Cancer: specific types
05222 Small cell lung cancer
11783 (Apaf1)
09172 Infectious disease: viral
05161 Hepatitis B
11783 (Apaf1)
05160 Hepatitis C
11783 (Apaf1)
05164 Influenza A
11783 (Apaf1)
05162 Measles
11783 (Apaf1)
05168 Herpes simplex virus 1 infection
11783 (Apaf1)
05169 Epstein-Barr virus infection
11783 (Apaf1)
09171 Infectious disease: bacterial
05134 Legionellosis
11783 (Apaf1)
05152 Tuberculosis
11783 (Apaf1)
09164 Neurodegenerative disease
05010 Alzheimer disease
11783 (Apaf1)
05012 Parkinson disease
11783 (Apaf1)
05014 Amyotrophic lateral sclerosis
11783 (Apaf1)
05016 Huntington disease
11783 (Apaf1)
05020 Prion disease
11783 (Apaf1)
05022 Pathways of neurodegeneration - multiple diseases
11783 (Apaf1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
11783 (Apaf1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
11783 (Apaf1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
WD40
WD40_WDHD1_1st
WD40_Prp19
WD40_CDC20-Fz
NB-ARC
APAF1_C
Beta-prop_EML_2
WDR55
Beta-prop_TEP1_2nd
EIF3I
WD40_MABP1-WDR62_2nd
APAF-1-like_WHD
Beta-prop_CAF1B_HIR1
Beta-prop_WDR90_POC16_2nd
ANAPC4_WD40
Beta-prop_EML
Beta-prop_WDR75_1st
WDR90_beta-prop_4th
Beta-prop_IFT122_1st
Beta-prop_RIG_2nd
CARD
NBCH_WD40
Beta-prop_EIPR1
Beta-prop_TEP1_C
Beta-prop_WDR19_1st
WD40_MABP1-WDR62_1st
Beta-prop_IFT140_1st
Beta-prop_Vps41
Beta-prop_SCAP
Beta-prop_HPS5
WD40_RFWD3
Beta-prop_NUP159_NUP214
eIF2A
Beta-prop_NWD2_C
Beta-prop_WDR35_TULP_N
WD40_like
Beta-prop_DCAF4
PEP5_VPS11_N
Beta-prop_WDR11_2nd
Beta-prop_WDR75_2nd
Beta-prop_SPT8
Ge1_WD40
Beta-prop_Nup120_160
Beta-prop_DCAF12
CARD_2
Utp8_b_propeller
KNTC1_N
WDR54
AAA_16
NPHP3_N
AAA_22
ATPase_2
AAA_18
NACHT
Motif
Other DBs
NCBI-GeneID:
11783
NCBI-ProteinID:
NP_001036023
MGI:
1306796
Ensembl:
ENSMUSG00000019979
UniProt:
O88879
Q5DU30
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:complement(90825173..90918688)
Genome browser
AA seq
1249 aa
AA seq
DB search
MDAKARNCLLQHREALEKDIKTSYIMDHMISNGVLSVIEEEKVKSQATQYQRAAALIKMI
LNKDNCAYISFYNALLHEGYKDLAALLQSGLPLVSSSSGKDTDGGITSFVRTVLCEGGVP
QRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSG
GVHWVSIGKQDKSGLLMKLQNLCMRLDQEESFSQRLPLNIEEAKDRLRVLMLRKHPRSLL
ILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVPVESGLGREKGLEILSLFVN
MKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYD
YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN
KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQPHTLSPDQEDC
MYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAV
CENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINK
KTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEV
LCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNKSNHLLLATGS
NDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSANERKS
INVKRFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSGLLAEIHTGHH
STIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSSFLTA
SDDQTIRVWETKKVCKNSAIVLKQEIDVVFQENETMVLAVDNIRGLQLIAGKTGQIDYLP
EAQVSCCCLSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLIS
SSEDSVIQVWNWQTGDYVFLQAHQETVKDFRLLQDSRLLSWSFDGTVKVWNVITGRIERD
FTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFDLLSPLHELKGHNGCVRCSAFSLDGI
LLATGDDNGEIRIWNVSDGQLLHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAGGYL
KWWNVATGDSSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE
NT seq
3750 nt
NT seq
+upstream
nt +downstream
nt
atggatgcaaaggcccgcaattgtttgcttcaacatagagaagctttggaaaaggacatc
aaaacatcctacatcatggatcacatgatcagtaatggcgtcttgtcagtgatagaggag
gagaaggtcaaaagtcaggccactcaatatcaacgagcagccgctttaattaaaatgata
cttaataaagacaactgtgcctacatttcattctacaacgctctgctacacgagggctat
aaggaccttgctgcgcttctgcagagtggccttcctcttgtgtcgtcttccagtggcaag
gacacagatggtggaataacttcatttgtaaggacagtgctgtgtgaaggtggagtaccc
cagaggccggttattttcgttactagaaagaagctggttcatgcgattcagcagaagctc
tggaaactgaatggagaaccagggtgggtcaccatctatgggatggcaggctgcggcaag
tctgtgttagctgcggaagccgttcgagatcactccctcttagaaggttgcttttcaggg
ggtgtacactgggtttccattggaaaacaagacaaatctgggcttctcatgaaactgcag
aatctgtgcatgcgcttggaccaagaagagagtttctctcagaggcttccacttaatatt
gaggaggccaaagaccgcctccgtgttctgatgctgcgcaaacacccaaggtctctgttg
atcttggatgatgtttgggatccttgggtgttaaaagcttttgacaatcagtgtcagatt
cttcttacaaccagagataagagtgttacagattcagtaatgggtcctaagcatgttgtc
cctgtggagagtggtctagggagagagaaaggacttgagatcttgtcactttttgttaac
atgaagaaagaagatctgccagcggaggctcacagtattataaaggaatgcaaaggttct
cctcttgtagtgtctttaattggtgcgcttttacgtgattttcccaatcgctgggcatac
tacctcagacagcttcagaataagcagtttaagagaataaggaagtcttcatcttatgat
tatgaggctctagatgaagccatgtcgataagtgttgaaatgctcagagaagacatcaaa
gactattacacagacctttccatccttcagaaggacgtcaaggtacctacaaaggtgttg
tgcgttctctgggacttggaaacggaagaagttgaagacatcctgcaggagttcgttaat
aagtctctcttattctgtaatcggaatggaaagtcattttgttattatttacatgatctt
caagtagattttcttacagagaagaatcgcagtcagcttcaggatctgcacaggaagatg
gtcactcagtttcagaggtattaccagccccacacgctgtctccagaccaggaggactgc
atgtattggtacaacttcctagcctatcacatggctagtgccaatatgcacaaagaactt
tgtgctttaatgttttccctggactggattaaagcaaaaacagaacttgtcggccctgcc
catctgattcacgagttcgtggcatataggcatatattggatgaaaaggattgtgcagtc
tgtgagaattttcaagagtttttatctttaaatggacacctccttggacgacagccattt
cctaatattgtacagctgggcctctgtgaaccagaaacttccgaagtttatcgacaagca
aagctgcaggccaagcaggagggggatactgggcgcctttacctggaatggataaacaaa
aaaactatcaagaatctgtcccgcttagtcgtccgcccccacacagatgctgtttaccac
gcgtgtttttctcaggatggtcagagaatagcttcttgtggggctgataaaaccttacag
gtgttcaaagccgagacaggagagaaacttcttgacatcaaagctcacgaagatgaggtg
ctttgctgcgcgttctcctcagacgacagttacatagcgacctgctcagcggataagaag
gttaagatttgggattctgcgactgggaagcttgtgcacacctacgacgagcactcggag
caagtcaattgctgccatttcaccaacaagagtaaccaccttctcttggccactgggtca
aatgatttcttcctcaagctctgggatttgaatcaaaaagaatgtcgaaataccatgttt
ggtcacacgaactcagtcaaccactgcaggttctcaccagacgatgagctcttggctagc
tgctcagctgacgggactttaaggctttgggatgtgagatcagcaaacgagaggaaaagc
attaatgtgaagcgcttcttcctgagttcagaagaccctccagaggatgtggaggtgatc
gtgaagtgttgttcctggtctgcagatggtgacaaaataatagtggcagcaaaaaacaaa
gtcctcctttttgatattcatactagtggcctattggcagagatccacacaggccatcac
agcaccatccagtactgtgacttctccccctatgaccatttggctgtgattgccctgtct
cagtactgtgtggagttgtggaacatagactcccgcctaaaggtggccgactgcagagga
catttgagttgggttcacggtgtgatgttttctcccgatggctcctcatttttgacagct
tctgatgaccaaacaataagggtctgggagacaaaaaaggtatgcaagaactctgccatc
gtgctaaagcaggaaatagacgtcgtgtttcaagagaacgaaacgatggtccttgcagtt
gacaacataagaggcctgcaactcattgctggaaaaacaggccagattgattacctgcct
gaagcccaagtgagttgctgctgcctcagtccacaccttgagtacgtggcattcggagat
gaagatggagccattaagattatagaacttccaaacaacagagtcttcagttctggggtt
gggcacaagaaagctgtgcggcacatccagttcacagctgatgggaagacactgatttca
agttctgaagattctgtgattcaggtatggaattggcagacaggggactatgtatttttg
caagcccaccaggaaacggtaaaggacttcaggctcctccaagattcaagattgctttct
tggtcatttgatggaacggtgaaggtgtggaatgtcattaccggaagaatagaaagagac
tttacttgtcatcagggcacagtgctttcctgtgctatctcttctgatgcgaccaagttt
tcatctacctctgctgataagactgccaagatctggagttttgacctcctttcccctctt
catgagctgaagggccataatggctgtgtccgctgctctgccttctcgctggatggcatc
ctgttggcaactggagatgacaatggagaaatccggatatggaatgtctcagatggccag
cttcttcattcgtgtgctccgatctcggtagaggaaggaactgctacccacggcggctgg
gtaactgatgtgtgcttctctcccgacagtaaaacgcttgtctctgctggaggatatctc
aagtggtggaatgttgccactggggactcctcacagaccttctacacaaatggaacaaac
ctcaagaaaatccacgtgtcccctgacttcagaacctatgtgactgtcgataatctcggt
attttatatattttacaggttttagagtga
DBGET
integrated database retrieval system
