Mus musculus (house mouse): 12371
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Entry
12371 CDS
T01002
Symbol
Casp9, APAF-3, CASP-9, Caspase-9, ICE-LAP6, Mch6
Name
(RefSeq) caspase 9
KO
K04399
caspase 9 [EC:
3.4.22.62
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01524
Platinum drug resistance
mmu04115
p53 signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu04210
Apoptosis
mmu04215
Apoptosis - multiple species
mmu04370
VEGF signaling pathway
mmu04919
Thyroid hormone signaling pathway
mmu05010
Alzheimer disease
mmu05012
Parkinson disease
mmu05014
Amyotrophic lateral sclerosis
mmu05016
Huntington disease
mmu05020
Prion disease
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05134
Legionellosis
mmu05145
Toxoplasmosis
mmu05152
Tuberculosis
mmu05160
Hepatitis C
mmu05161
Hepatitis B
mmu05162
Measles
mmu05163
Human cytomegalovirus infection
mmu05164
Influenza A
mmu05167
Kaposi sarcoma-associated herpesvirus infection
mmu05168
Herpes simplex virus 1 infection
mmu05169
Epstein-Barr virus infection
mmu05170
Human immunodeficiency virus 1 infection
mmu05200
Pathways in cancer
mmu05210
Colorectal cancer
mmu05212
Pancreatic cancer
mmu05213
Endometrial cancer
mmu05215
Prostate cancer
mmu05222
Small cell lung cancer
mmu05223
Non-small cell lung cancer
mmu05416
Viral myocarditis
mmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
12371 (Casp9)
04151 PI3K-Akt signaling pathway
12371 (Casp9)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
12371 (Casp9)
04215 Apoptosis - multiple species
12371 (Casp9)
04115 p53 signaling pathway
12371 (Casp9)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
12371 (Casp9)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
12371 (Casp9)
09162 Cancer: specific types
05210 Colorectal cancer
12371 (Casp9)
05212 Pancreatic cancer
12371 (Casp9)
05215 Prostate cancer
12371 (Casp9)
05213 Endometrial cancer
12371 (Casp9)
05222 Small cell lung cancer
12371 (Casp9)
05223 Non-small cell lung cancer
12371 (Casp9)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
12371 (Casp9)
05161 Hepatitis B
12371 (Casp9)
05160 Hepatitis C
12371 (Casp9)
05164 Influenza A
12371 (Casp9)
05162 Measles
12371 (Casp9)
05168 Herpes simplex virus 1 infection
12371 (Casp9)
05163 Human cytomegalovirus infection
12371 (Casp9)
05167 Kaposi sarcoma-associated herpesvirus infection
12371 (Casp9)
05169 Epstein-Barr virus infection
12371 (Casp9)
09171 Infectious disease: bacterial
05134 Legionellosis
12371 (Casp9)
05152 Tuberculosis
12371 (Casp9)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
12371 (Casp9)
09164 Neurodegenerative disease
05010 Alzheimer disease
12371 (Casp9)
05012 Parkinson disease
12371 (Casp9)
05014 Amyotrophic lateral sclerosis
12371 (Casp9)
05016 Huntington disease
12371 (Casp9)
05020 Prion disease
12371 (Casp9)
05022 Pathways of neurodegeneration - multiple diseases
12371 (Casp9)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
12371 (Casp9)
05416 Viral myocarditis
12371 (Casp9)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
12371 (Casp9)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmu01009
]
12371 (Casp9)
01002 Peptidases and inhibitors [BR:
mmu01002
]
12371 (Casp9)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.62 caspase-9
12371 (Casp9)
Protein phosphatases and associated proteins [BR:
mmu01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
12371 (Casp9)
Peptidases and inhibitors [BR:
mmu01002
]
Cysteine peptidases
Family C14: caspase family
12371 (Casp9)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C14
CARD
CARD_2
Motif
Other DBs
NCBI-GeneID:
12371
NCBI-ProteinID:
NP_056548
MGI:
1277950
Ensembl:
ENSMUSG00000028914
UniProt:
Q8C3Q9
LinkDB
All DBs
Position
4:141520923..141543289
Genome browser
AA seq
454 aa
AA seq
DB search
MDEADRQLLRRCRVRLVSELQVAELWDALLSRELFTRDMIEDIQQAGSGSRRDQARQLVT
DLETRGRQALPLFISCLEDTGQGTLASLLQSGRQAAKQDPEAVKPLDHLVPVVLGPMGLT
AKEQRVVKLDPSQPAVGNLTPVVLGPEELWPARLKPEVLRPETPRPVDIGSGGAHDVCVP
GKIRGHADMAYTLDSDPCGHCLIINNVNFCPSSGLGTRTGSNLDRDKLEHRFRWLRFMVE
VKNDLTAKKMVTALMEMAHRNHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIEK
IVNIFNGSGCPSLGGKPKLFFIQACGGEQKDHGFEVACTSSQGRTLDSDSEPDAVPYQEG
PRPLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGILEQWARSEDLQS
LLLRVANAVSAKGTYKQIPGCFNFLRKKLFFKTS
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atggacgaggcggaccggcagctcctgcggcgatgcagggtgcgcctagtgagcgagctg
caagtcgcggagctctgggacgctctgctgagtcgagagctcttcacgcgcgacatgatc
gaggatattcagcaggcaggatctgggtctcggcgggatcaggccaggcagctggtcaca
gaccttgagacccgagggaggcaggcccttcctctcttcatctcctgcttagaggacaca
ggccaaggcaccctggcttcactcttgcaaagcggtcggcaagcagccaagcaggatcca
gaggctgttaaacccctagaccacctggtgcctgtggtcctgggaccaatgggactcaca
gcaaaggagcagagagtagtgaagctggacccgtcacagcctgccgtgggaaacctcacc
ccagtggtgctggggccagaagagctctggcctgctcggctcaagccagaggttctcaga
ccagaaacacccaggcccgtggacattggttctggcggagctcatgatgtctgtgttcca
gggaagatcaggggacatgcagatatggcatacaccctggattcggatccctgtggccac
tgcctcatcatcaacaatgtgaacttctgcccttcctcggggctcggcacacgcacgggc
tccaacttggaccgtgacaaacttgagcaccgattccgctggctgcgcttcatggtggag
gtgaagaacgacctgactgccaagaaaatggtcacggctttgatggagatggcacaccgg
aaccaccgtgccctggactgctttgtggtggtcatcctctctcatggctgccaggccagc
cacctccagttcccgggtgctgtctatgggacagatggatgctccgtgtccattgagaaa
attgtgaatatcttcaacgggagcggctgccccagcctgggagggaagcccaagctcttc
ttcatccaggcctgcggtggtgagcagaaagaccatggctttgaggtggcctgcacttcc
tctcaaggcaggaccttggacagtgactctgagccagatgctgtcccctatcaggaaggc
ccaaggcccttggaccagctggatgctgtgtcaagtttgcctacccccagtgacatcctt
gtgtcctactccaccttcccaggttttgtctcctggagggacaagaaaagtggctcctgg
tacatcgagaccttggatggcattctggagcagtgggctcgctctgaagacctgcagtcc
ctccttctcagggttgccaatgctgtttctgcgaaagggacttacaagcagattcctggc
tgttttaacttcctccggaaaaagctgttttttaaaacttcatga
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