K04399                      KO                                     

caspase 9 [EC:]
ko01524  Platinum drug resistance
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04210  Apoptosis
ko04215  Apoptosis - multiple species
ko04370  VEGF signaling pathway
ko04919  Thyroid hormone signaling pathway
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05016  Huntington disease
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05130  Pathogenic Escherichia coli infection
ko05134  Legionellosis
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05212  Pancreatic cancer
ko05213  Endometrial cancer
ko05215  Prostate cancer
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05416  Viral myocarditis
ko05417  Lipid and atherosclerosis
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    K04399  CASP9; caspase 9
   04151 PI3K-Akt signaling pathway
    K04399  CASP9; caspase 9
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04399  CASP9; caspase 9
   04215 Apoptosis - multiple species
    K04399  CASP9; caspase 9
   04115 p53 signaling pathway
    K04399  CASP9; caspase 9
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K04399  CASP9; caspase 9
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04399  CASP9; caspase 9
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04399  CASP9; caspase 9
   05212 Pancreatic cancer
    K04399  CASP9; caspase 9
   05215 Prostate cancer
    K04399  CASP9; caspase 9
   05213 Endometrial cancer
    K04399  CASP9; caspase 9
   05222 Small cell lung cancer
    K04399  CASP9; caspase 9
   05223 Non-small cell lung cancer
    K04399  CASP9; caspase 9
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04399  CASP9; caspase 9
   05161 Hepatitis B
    K04399  CASP9; caspase 9
   05160 Hepatitis C
    K04399  CASP9; caspase 9
   05164 Influenza A
    K04399  CASP9; caspase 9
   05162 Measles
    K04399  CASP9; caspase 9
   05168 Herpes simplex virus 1 infection
    K04399  CASP9; caspase 9
   05163 Human cytomegalovirus infection
    K04399  CASP9; caspase 9
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04399  CASP9; caspase 9
   05169 Epstein-Barr virus infection
    K04399  CASP9; caspase 9
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04399  CASP9; caspase 9
   05134 Legionellosis
    K04399  CASP9; caspase 9
   05152 Tuberculosis
    K04399  CASP9; caspase 9
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04399  CASP9; caspase 9
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04399  CASP9; caspase 9
   05012 Parkinson disease
    K04399  CASP9; caspase 9
   05014 Amyotrophic lateral sclerosis
    K04399  CASP9; caspase 9
   05016 Huntington disease
    K04399  CASP9; caspase 9
   05020 Prion disease
    K04399  CASP9; caspase 9
   05022 Pathways of neurodegeneration - multiple diseases
    K04399  CASP9; caspase 9
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04399  CASP9; caspase 9
   05416 Viral myocarditis
    K04399  CASP9; caspase 9
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K04399  CASP9; caspase 9
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04399  CASP9; caspase 9
   01002 Peptidases and inhibitors
    K04399  CASP9; caspase 9
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases  caspase-9
     K04399  CASP9; caspase 9
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04399  CASP9; caspase 9
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C14: caspase family
   K04399  CASP9; caspase 9
HSA: 842(CASP9)
PTR: 456457(CASP9)
PPS: 100992567(CASP9)
GGO: 101130414(CASP9)
PON: 100460459(CASP9)
NLE: 100597173(CASP9)
MCC: 694544(CASP9)
MCF: 102126830(CASP9)
CSAB: 103225550(CASP9)
CATY: 105599419(CASP9)
RRO: 104677696(CASP9)
RBB: 108524269(CASP9)
TFN: 117093253(CASP9)
CJC: 100409028(CASP9)
SBQ: 101051525(CASP9)
MMUR: 105870442(CASP9)
MMU: 12371(Casp9)
MCAL: 110293440(Casp9)
MPAH: 110323338(Casp9)
RNO: 58918(Casp9)
MCOC: 116096967(Casp9)
MUN: 110545060(Casp9)
PLEU: 114700859(Casp9)
NGI: 103725336(Casp9)
HGL: 101702898(Casp9)
CCAN: 109692548(Casp9)
OCU: 100101592(CASP9)
TUP: 102470940(CASP9)
CFA: 487432(CASP9)
VVP: 112929772(CASP9)
AML: 100483760(CASP9)
UMR: 103666628(CASP9)
UAH: 113270476(CASP9)
ORO: 101362812(CASP9)
ELK: 111154673
MPUF: 101681290(CASP9)
EJU: 114213333(CASP9)
FCA: 768260(CASP9)
PTG: 102967404(CASP9)
PPAD: 109274153(CASP9)
AJU: 106975594(CASP9)
BTA: 100140945(CASP9)
BOM: 102268660(CASP9)
BIU: 109570433(CASP9)
BBUB: 102412012(CASP9)
CHX: 102174681(CASP9)
OAS: 101110953(CASP9)
SSC: 100518913(CASP9)
CFR: 102519816(CASP9)
CDK: 105107056(CASP9)
BACU: 103010071(CASP9)
LVE: 103086745(CASP9)
OOR: 101271677(CASP9)
DLE: 111187099(CASP9)
PCAD: 102989458(CASP9)
ECB: 100054331(CASP9)
EPZ: 103565016(CASP9)
EAI: 106828005(CASP9)
MYB: 102254877(CASP9)
MYD: 102759481(CASP9)
MMYO: 118677148(CASP9)
MNA: 107531542(CASP9)
HAI: 109381302(CASP9)
DRO: 112299456(CASP9)
SHON: 118986319(CASP9)
AJM: 119049966(CASP9)
MMF: 118626427(CASP9)
PALE: 102878565(CASP9)
RAY: 107501830(CASP9)
LAV: 100656597(CASP9)
TMU: 101355103
MDO: 100027338(CASP9)
SHR: 100931481(CASP9)
PCW: 110198824(CASP9)
OAA: 100092345(CASP9)
GGA: 426970(CASP9)
MGP: 100550410(CASP9)
CJO: 107323418(CASP9)
NMEL: 110408509(CASP9)
APLA: 101795386(CASP9)
ACYG: 106040238(CASP9)
TGU: 100227981(CASP9)
LSR: 110472268(CASP9)
SCAN: 103824350(CASP9)
GFR: 102039030(CASP9)
FAB: 101808292(CASP9)
PHI: 102108950(CASP9)
PMAJ: 107213687(CASP9)
CCAE: 111938513(CASP9)
CCW: 104697549(CASP9)
ETL: 114068717(CASP9)
FPG: 101914844(CASP9)
FCH: 102054465(CASP9)
CLV: 102093506(CASP9)
EGZ: 104133155(CASP9)
NNI: 104011166(CASP9)
ACUN: 113487796(CASP9)
PADL: 103918063(CASP9)
AAM: 106493414(CASP9)
ASN: 102384999(CASP9)
AMJ: 102573968(CASP9)
PSS: 102443524(CASP9)
CMY: 102939753(CASP9)
CPIC: 101944555(CASP9)
ACS: 100560103(casp9)
PVT: 110072690(CASP9)
PBI: 103063403(CASP9)
PMUR: 107291376(CASP9)
TSR: 106547434(CASP9)
PMUA: 114602391(CASP9)
GJA: 107124463(CASP9)
XLA: 373560(casp9.S)
XTR: 100144708(casp9)
NPR: 108797190(CASP9)
DRE: 492763(casp9)
SGH: 107591141(casp9) 107593914
IPU: 108276164(casp9)
PHYP: 113530268(casp9)
AMEX: 103034324
EEE: 113576299(casp9)
TRU: 101075121(casp9)
LCO: 104939007(casp9)
NCC: 104954971
MZE: 101487562(casp9)
ONL: 100700134(casp9)
OLA: 101157857(casp9)
XMA: 102226741(casp9)
XCO: 114148510(casp9)
PRET: 103467149(casp9)
CVG: 107091512(casp9)
KMR: 108233046(casp9)
ALIM: 106513111(casp9)
AOCE: 111572548(casp9)
CSEM: 103385017(casp9)
POV: 109630724(casp9)
LCF: 108882570(casp9)
SDU: 111236985(casp9)
SLAL: 111651602(casp9)
HCQ: 109511699(casp9)
BPEC: 110167143(casp9)
MALB: 109967174(casp9)
SASA: 106567147 106572551(casp9)
SALP: 111976406 111976415(casp9)
ELS: 105028691(casp9)
SFM: 108939364(casp9)
LCM: 102362720(CASP9)
CMK: 103187647(casp9)
RTP: 109927787(casp9)
SKO: 100376094
NVE: 5512986
EPA: 110241763
DGT: 114518280
HMG: 101235218
AQU: 100633941
 » show all
Srinivasula SM, Ahmad M, Guo Y, Zhan Y, Lazebnik Y, Fernandes-Alnemri T, Alnemri ES
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis.
Cancer Res 59:999-1002 (1999)
Duan H, Orth K, Chinnaiyan AM, Poirier GG, Froelich CJ, He WW, Dixit VM
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
J Biol Chem 271:16720-4 (1996)
Raina D, Pandey P, Ahmad R, Bharti A, Ren J, Kharbanda S, Weichselbaum R, Kufe D
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage.
J Biol Chem 280:11147-51 (2005)

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