Mus musculus (house mouse): 12649
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Entry
12649 CDS
T01002
Symbol
Chek1, Chk1, rad27
Name
(RefSeq) checkpoint kinase 1
KO
K02216
serine/threonine-protein kinase CHEK1 [EC:
2.7.11.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04110
Cell cycle
mmu04115
p53 signaling pathway
mmu04218
Cellular senescence
mmu05166
Human T-cell leukemia virus 1 infection
mmu05170
Human immunodeficiency virus 1 infection
mmu05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
12649 (Chek1)
04115 p53 signaling pathway
12649 (Chek1)
04218 Cellular senescence
12649 (Chek1)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
12649 (Chek1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
12649 (Chek1)
05170 Human immunodeficiency virus 1 infection
12649 (Chek1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
12649 (Chek1)
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
mmu03400
]
12649 (Chek1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
12649 (Chek1)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: CAMK group
CAMKL family
12649 (Chek1)
DNA repair and recombination proteins [BR:
mmu03400
]
Eukaryotic type
Check point factors
Other check point factors
12649 (Chek1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
12649
NCBI-ProteinID:
NP_031717
MGI:
1202065
Ensembl:
ENSMUSG00000032113
UniProt:
O35280
LinkDB
All DBs
Position
9:complement(36619935..36637897)
Genome browser
AA seq
476 aa
AA seq
DB search
MAVPFVEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINK
MLSHENVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY
LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLK
RKEFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
LLHKILVETPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDF
SPVNNGSSEETVKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPEHMLVNSQLL
GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTTDRR
NNKLIFKINLVEMDEKILVDFRLSKGDGLEFKRHFLKIKGKLSDVVSSQKVWFPVT
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgccttttgtggaagactgggatttggtgcaaactttgggagaaggtgcctat
ggagaagttcaacttgctgtgaatagaataactgaagaagctgttgcagtgaaaattgta
gacatgaagcgggccatagactgtccagaaaatattaagaaagagatctgcatcaataaa
atgttaagccacgagaatgtagtgaaattctatggccacaggagggaaggccatatccag
tatctgtttctggagtactgtagtggaggagaactttttgatagaattgagccagacata
gggatgcctgaacaagatgctcagaggttcttccaccaactcatggcaggggtggtttat
cttcatggaattggaataactcacagggatattaaaccagaaaacctcctcttggatgaa
agggataacctcaaaatctctgactttggcttggcaacggtatttcggcataataatcgt
gaacgcttactgaacaagatgtgtgggactttaccttatgttgctccggagcttctaaag
agaaaagaatttcatgcagaaccagttgatgtttggtcctgtggaatagtacttactgca
atgttggctggagaattgccgtgggaccagcccagtgatagctgtcaggaatattctgat
tggaaagaaaaaaaaacctatctcaatccttggaaaaaaattgattctgctcctctggct
ttgcttcataaaattctagttgagactccatcagcaaggatcaccatcccagacattaag
aaagatagatggtacaacaaaccacttaacagaggagcaaagaggccacgcgccacatca
ggtggtatgtcagagtcttctagtggattctctaagcacattcattccaatttggacttt
tctccagtaaataatggttccagtgaagaaaccgtgaagttctctagttcccagccagag
ccgagaacagggctttccttgtgggacactggtccctcgaacgtggacaaactggttcag
ggcatcagtttttcccagcctacgtgtcctgagcatatgcttgtaaacagtcagttactc
ggtacccctggatcttcacagaacccctggcagcgcttggtcaaaaggatgacacgattc
tttactaaattggatgcggacaaatcttaccaatgcctgaaagagaccttcgagaagttg
ggctatcagtggaagaagagttgtatgaatcaggttactgtatcaacaactgatagaaga
aacaataagttgattttcaaaataaatttggtagaaatggatgagaagatactggttgac
ttccgactttctaagggtgatggattagagttcaagagacacttcctgaagattaaaggg
aagctcagcgatgttgtgagcagccagaaggtttggtttcctgttacatga
DBGET
integrated database retrieval system
