KEGG ORTHOLOGY: K02216

ORTHOLOGY: K02216

Entry

K02216                      KO

Symbol

CHEK1

Name

serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]

Pathway

map04110

Cell cycle

map04111

Cell cycle - yeast

map04113

Meiosis - yeast

map04115

p53 signaling pathway

map04218

Cellular senescence

map05166

Human T-cell leukemia virus 1 infection

map05170

Human immunodeficiency virus 1 infection

map05203

Viral carcinogenesis

Disease

H01897

Oocyte/zygote/embryo maturation arrest

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04111 Cell cycle - yeast
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04113 Meiosis - yeast
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04115 p53 signaling pathway
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04218 Cellular senescence
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   05170 Human immunodeficiency virus 1 infection
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K02216  CHEK1; serine/threonine-protein kinase CHEK1
Protein kinases [BR:ko01001]
Serine/threonine kinases: CAMK group
  CAMKL family
   K02216  CHEK1; serine/threonine-protein kinase CHEK1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Check point factors
   Other check point factors
    K02216  CHEK1; serine/threonine-protein kinase CHEK1

Other DBs

COG:

COG0515

Genes

HSA:	1111(CHEK1)

PTR:	739836(CHEK1)

PPS:	100982317(CHEK1)

GGO:	101131993(CHEK1)

PON:	100436550(CHEK1)

PPYG:

129007121(CHEK1)

NLE:	100596673(CHEK1)

HMH:	116477131(CHEK1)

SSYN:

129479838(CHEK1)

MCC:	713358(CHEK1)

MCF:	101926004(CHEK1)

MTHB:

126934853

MNI:	105476258(CHEK1)

CSAB:

103248769(CHEK1)

CATY:

105582604(CHEK1)

PANU:

101019580(CHEK1)

TGE:	112606274(CHEK1)

MLEU:

105554711(CHEK1)

RRO:	104653937(CHEK1)

RBB:	108542336(CHEK1)

TFN:	117080890(CHEK1)

PTEH:

111540298(CHEK1)

CANG:

105506457(CHEK1)

CJC:	100405400(CHEK1)

SBQ:	101044792(CHEK1)

CIMI:

108300793(CHEK1)

ANAN:

105717868(CHEK1)

CSYR:

103273961(CHEK1)

MMUR:

105881584(CHEK1)

LCAT:

123641207(CHEK1)

PCOQ:

105821450(CHEK1)

OGA:	100942218(CHEK1)

MMU:	12649(Chek1)

MCAL:

110301495(Chek1)

MPAH:

110327308(Chek1)

RNO:	140583(Chek1)

MCOC:

116071915(Chek1)

ANU:	117699162(Chek1)

ASYL:

127689247(Chek1)

MUN:	110549439(Chek1)

CGE:	100751099(Chek1)

MAUA:

101843181(Chek1)

PROB:

127231512(Chek1)

PLEU:

114684003(Chek1)

PMAV:

102928359(Chek1)

MORG:

121451627(Chek1)

MFOT:

126490587

AAMP:

119809693(Chek1)

NGI:	103735579(Chek1)

HGL:	101701035(Chek1)

CPOC:

100719613(Chek1)

CCAN:

109700303(Chek1)

DORD:

105980875(Chek1)

DSP:	122104226(Chek1) 122123350

DMER:

138821385(Chek1) 138838852

PLOP:

125349506(Chek1)

NCAR:

124958320

MMMA:

107153495(Chek1)

ITI:	101968394(Chek1)

OCU:

100345729

OPI:	101533794(CHEK1)

OCZ:	121154016(CHEK1)

TUP:	102480757(CHEK1)

GVR:	103583154 103608913(CHEK1)

CFA:	609767(CHEK1)

CLUD:

112671112(CHEK1)

VVP:	112920276(CHEK1)

VLG:	121500173(CHEK1)

NPO:	129497889(CHEK1)

AML:	100467858(CHEK1)

UMR:	103660629(CHEK1)

UAH:	113259903(CHEK1)

UAR:	123792711(CHEK1)

ELK:

111153780

LLV:

125110264

MPUF:

101685590(CHEK1)

MNP:	132026435(CHEK1)

MLK:	131838215(CHEK1)

NVS:	122912413(CHEK1)

ORO:	101362614(CHEK1)

EJU:	114226008(CHEK1)

ZCA:	113915303(CHEK1)

MLX:	118013370(CHEK1)

NSU:	110586234(CHEK1)

LWW:	102731543(CHEK1)

FCA:	101083365(CHEK1)

PYU:	121035597(CHEK1)

PCOO:

112865240(CHEK1)

PBG:	122483117(CHEK1)

PVIV:

125146989(CHEK1)

LRUF:

124505184

LGF:	123600894(CHEK1)

AJU:

106976641

PTG:	102948766(CHEK1)

PPAD:

109257420(CHEK1)

PUC:

125939340

PLEZ:

122199660(CHEK1)

HHV:	120243919(CHEK1)

BTA:	513678(CHEK1)

BOM:	102266500(CHEK1)

BIU:	109554657(CHEK1)

BBUB:

102398478(CHEK1)

BBIS:

104980692(CHEK1)

CHX:	102184881(CHEK1)

OAS:	101111403(CHEK1)

BTAX:

128068939(CHEK1)

CSUM:

138083226(CHEK1)

ODA:	120874428(CHEK1)

CCAD:

122430784(CHEK1)

MREE:

136145685 136169537(CHEK1)

OVR:	110127455(CHEK1)

MBEZ:

129548956(CHEK1)

SSC:	100511709(CHEK1)

CFR:	102505566(CHEK1)

CBAI:

105074175(CHEK1)

CDK:	105094454(CHEK1)

VPC:	102526561(CHEK1)

BACU:

103015970(CHEK1)

BMUS:

118900280(CHEK1)

LVE:	103073805(CHEK1)

OOR:	101270160(CHEK1)

LALB:

132525450(CHEK1)

GMF:	115843921(CHEK1)

DDP:	132429428(CHEK1)

DLE:	111167465(CHEK1)

PCAD:

102989266(CHEK1)

PSIU:

116757609(CHEK1)

PPHC:

136126492(CHEK1)

NASI:

112396826(CHEK1)

ECB:	100064353(CHEK1)

EPZ:	103557005(CHEK1)

EAI:	106835962(CHEK1)

MYB:	102255905(CHEK1)

MYD:	102751668(CHEK1)

MMYO:

118678155(CHEK1)

MLF:	102437641(CHEK1)

MDT:	132221590(CHEK1)

MYUM:

138997819(CHEK1)

PKL:	118725741(CHEK1)

EFUS:

103286938(CHEK1)

MNA:	107530590(CHEK1)

DRO:	112301845(CHEK1)

SHON:

118981405(CHEK1)

AJM:	119041045(CHEK1)

PDIC:

114509510(CHEK1)

PHAS:

123832554(CHEK1)

MMF:	118639911(CHEK1)

PPAM:

129086390(CHEK1)

HAI:	109391372(CHEK1)

RFQ:	117017223(CHEK1)

PALE:

102882405(CHEK1)

PGIG:

120610459(CHEK1)

PVP:	105296813(CHEK1)

RAY:	107498938(CHEK1)

MJV:	108401047(CHEK1)

TOD:	119240818(CHEK1)

SARA:

101540894(CHEK1) 105943527

SFUM:

130024250(CHEK1)

SETR:

126016046(CHEK1)

LAV:	100658513(CHEK1)

TMU:

101345463

ETF:	101640005(CHEK1)

DNM:	101441252(CHEK1)

MDO:	100016170(CHEK1)

GAS:	123238925(CHEK1)

SHR:	100933648(CHEK1)

AFZ:

127554847

PCW:	110218134(CHEK1)

TVP:	118838477(CHEK1)

PBRV:

138155438(CHEK1) 138162614

MLAO:

141508089(CHEK1)

OAA:	100090345(CHEK1)

TACU:

119935092(CHEK1)

GGA:	374260(CHEK1)

PCOC:

116233040(CHEK1)

MGP:	100547861(CHEK1)

CJO:	107324224(CHEK1)

TPAI:

128087515(CHEK1)

LMUT:

125703744(CHEK1)

NMEL:

110387692(CHEK1)

APLA:

101790669(CHEK1)

ACYG:

106040556(CHEK1)

CATA:

118252468(CHEK1)

AFUL:

116497895(CHEK1)

TGU:	100219597(CHEK1)

LSR:	110468180(CHEK1)

SCAN:

103822842(CHEK1)

PMOA:

120508383(CHEK1)

OTC:	121340821(CHEK1)

PRUF:

121360614(CHEK1)

ATRC:

139601011(CHEK1)

GFR:	102039036(CHEK1)

FAB:	101815748(CHEK1)

OMA:	130262435(CHEK1)

PHI:	102103508(CHEK1)

PMAJ:

107214301(CHEK1)

CCAE:

111939252(CHEK1)

CCW:	104692217(CHEK1)

CBRC:

103618545(CHEK1)

ACOE:

138098276(CHEK1)

ETL:	114064599(CHEK1)

ZAB:	102064035(CHEK1)

ZLE:	135457438(CHEK1)

ACHL:

103807438(CHEK1)

SVG:	106860748(CHEK1)

MMEA:

130583027(CHEK1)

HRT:	120762582(CHEK1)

SATI:

136370965(CHEK1)

CFAI:

136300749(CHEK1)

CCIC:

134053650(CHEK1)

FPG:	101911598(CHEK1)

FCH:	102048652(CHEK1)

NNT:	104400295(CHEK1)

SHAB:

115616326(CHEK1)

ACUN:

113488427(CHEK1)

SURA:

141935140(CHEK1)

TALA:

116961442(CHEK1)

ACHC:

115344766(CHEK1)

HLE:	104840506(CHEK1)

AGEN:

126038521

HHAR:

128141511(CHEK1)

GCL:

127025784

DPUB:

104308049(CHEK1)

PPUS:

135191185(CHEK1)

EGZ:	104129228(CHEK1)

NNI:	104016679(CHEK1)

CBOR:

142092727(CHEK1)

CBOY:

140661800(CHEK1)

MAME:

142418873(CHEK1)

CLV:	102094428(CHEK1)

CNIC:

135998822(CHEK1)

MUI:

104539884

PGUU:

104464013(CHEK1)

CUCA:

104066084(CHEK1)

GAME:

129196117(CHEK1)

CPEA:

104398046(CHEK1)

RTD:

128918724

CRID:

134524953(CHEK1)

LMIC:

141732319(CHEK1)

AROW:

112968927(CHEK1)

ASN:	102385348(CHEK1)

AMJ:	102574519(CHEK1)

CPOO:

109317977(CHEK1)

GGN:	109291782(CHEK1)

PSS:	102451245(CHEK1)

CIZ:	142001539(CHEK1)

CMY:	102945662(CHEK1)

CCAY:

125625503(CHEK1)

DCC:	119846783(CHEK1)

CPIC:

101933610(CHEK1)

TST:	117868633(CHEK1)

CABI:

116818797(CHEK1)

MRV:	120375393(CHEK1)

ACS:	100564808(chek1)

ASAO:

132782654(CHEK1)

PVT:	110070287(CHEK1)

PBI:	103064116(CHEK1)

PMUR:

107296402 107296403

CTIG:

120313956(CHEK1)

TSR:	106545333(CHEK1)

PGUT:

117668192(CHEK1)

PCAE:

139323085(CHEK1)

APRI:

131203972(CHEK1)

PTEX:

113451811(CHEK1)

NSS:	113427162(CHEK1)

VKO:	123027171(CHEK1) 123033920

PMUA:

114585208(CHEK1)

PRAF:

128402660(CHEK1)

ZVI:	118097373(CHEK1)

HCG:	128333804(CHEK1)

GJA:	107117803(CHEK1)

STOW:

125442177(CHEK1)

EMC:	129342148(CHEK1)

XLA:	108696394(chek1.L) 398191(chek1.S)

XTR:	100038224(chek1)

NPR:	108783681(CHEK1) 108792688

RTEM:

120915700(CHEK1)

ACAT:

141111346(CHEK1)

PADS:

140340747(CHEK1)

BBUF:

121000276(CHEK1)

BGAR:

122926812(CHEK1)

DTC:	141097631(CHEK1)

PWL:	138285002(CHEK1)

MUO:	115474693(CHEK1)

GSH:	117361002(CHEK1)

DRE:	393162(chek1)

SRX:	107706535 107719013

SANH:

107681196 107703487

SGH:	107548125 107551636

CCAR:

109099921(chek1)

CAUA:

113038615 113064276

CGIB:

127941762 127985384

PTET:

122326226(chek1)

LROH:

127152033(chek1)

GRF:	141292628(chek1)

OMC:	131529448(chek1)

PPRM:

120494746(chek1)

RKG:	130096492(chek1)

MAMB:

125253492(chek1)

CIDE:

127504163

CERY:

137012864(chek1)

MASI:

127429224

TROS:

130570377(chek1)

TDW:	130408027(chek1)

MANU:

129423375(chek1)

PDAB:

135776866(chek1)

IPU:

108278491

IFU:	128622434(chek1)

PHYP:

113541633(chek1)

SMEO:

124398465(chek1)

TFD:	113634915(chek1)

TVC:	132859790(chek1)

CGAR:

128507571(chek1)

NGRA:

132895452(chek1)

TRN:	134330383(chek1)

AMEX:

103021956(chek1)

CMAO:

118820153(chek1)

EEE:	113573544(chek1)

CHAR:

105895358(chek1)

SPIL:

134079935(chek1)

ASAD:

121708582(chek1)

TRU:	101069769(chek1)

TFS:	130537480(chek1)

TNG:	GSTEN00018969G001

LCO:	104929933(chek1)

NCC:	104964655(chek1)

TBEN:

117490151(chek1)

CGOB:

115018952(chek1)

PGEO:

117458706(chek1)

GACU:

117535558(chek1)

EMAC:

134872535(chek1)

ELY:	117262759(chek1)

EFO:	125898268(chek1)

PLEP:

121952155(chek1)

SLUC:

116064872(chek1)

ECRA:

117955169(chek1)

ESP:	116700025(chek1)

PFLV:

114566919(chek1)

GAT:	120822688(chek1)

PPUG:

119215834(chek1)

AFB:	129113508(chek1)

CLUM:

117743221(chek1)

PSWI:

130189448(chek1)

CANA:

137802743(chek1)

CVE:	137876699(chek1)

MSAM:

119895100(chek1)

SCHU:

122888650(chek1)

CUD:	121518410(chek1)

SPUL:

138603581(chek1)

LMIX:

132987885(chek1)

HTC:	141791343(chek1)

ALAT:

119031422(chek1)

ASTR:

137606371(chek1)

MZE:	101487018(chek1)

ONL:	100707719(chek1)

OAU:	116313090(chek1)

OLA:	101170780(chek1)

OML:	112140828(chek1)

CSAI:

133460279(chek1)

XMA:	102238315(chek1)

XCO:	114152470(chek1)

XHE:	116729004(chek1)

PRET:

103475471(chek1)

PFOR:

103142157(chek1)

PLAI:

106956156(chek1)

PMEI:

106921319(chek1)

GAF:	122844415(chek1)

PPRL:

129368826(chek1)

CVG:	107098496(chek1)

CTUL:

119775819(chek1)

GMU:	124875974(chek1) 124876660

NFU:	107386371(chek1)

KMR:	108236904(chek1)

ALIM:

106514075(chek1)

NWH:	119420041(chek1)

AOCE:

111580652(chek1)

EJA:	138196409(chek1)

BFRE:

138634750(chek1)

MCEP:

125021744(chek1)

CSEM:

103395155(chek1)

POV:	109628292(chek1)

SSEN:

122779755(chek1)

SSOE:

131458944(chek1)

HHIP:

117774183(chek1)

HSP:	118122685(chek1)

PPLT:

128456608(chek1)

SMAU:

118301186(chek1)

LCF:

108893136

SDU:	111234478(chek1)

SLAL:

111666155(chek1)

XGL:	120802605(chek1)

HCQ:	109517900(chek1)

SSCV:

125982679(chek1)

SBIA:

133491952(chek1)

PEE:	133415819(chek1)

PTAO:

133467490(chek1)

BPEC:

110158508(chek1)

ENY:	140360341(chek1)

MALB:

109959175(chek1)

BSPL:

114869608(chek1)

SJO:	128371820(chek1)

SSCO:

133994438(chek1)

TTY:	137195593(chek1)

GMH:	115547775(chek1)

SASA:

106563964(chek1)

STRU:

115204711(chek1)

OTW:	112236999(chek1)

OMY:	110510298(chek1)

OGO:	124007528(chek1)

ONE:	115123283(chek1)

OKI:	109881514(chek1)

OKE:	118371844(chek1)

OMM:	135544036(chek1)

OCLA:

139388254

SALP:

112078987(chek1)

SNH:	120041456(chek1)

SFON:

129864227(chek1)

CCLU:

121557942 123484461

ELS:	105009476(chek1)

OEP:	134039827(chek1)

SFM:	108924764(chek1)

PKI:	111837953(chek1)

AANG:

118235259(chek1)

AROT:

135263984(chek1)

CCOG:

133133111(chek1)

LOC:	102696807(chek1)

PSPA:

121309546

ARUT:

117397432 117966660

LCM:	102357495(CHEK1)

CMK:	103180289(chek1)

RTP:	109921452(chek1)

CPLA:

122540735(chek1)

CPUN:

140494098(chek1)

HOC:	132829610(chek1)

SCAU:

119954184(chek1)

LERI:

129712431(chek1)

HAKA:

140716796(chek1)

PMRN:

116948227(CHEK1)

LRJ:	133342135 133342142

BFO:

BBEL:

CIN:

SCLV:

SPU:	115921093 592974(Chk1)

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG17161(grp)

DER:

6547505

DSE:

6614402

DSI:	Dsimw501_GD24070(Dsim_GD24070)

DYA:	Dyak_GE12755

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17268

DAZ:

108610244

DNV:

108658305

DHE:

111596373

DVI:	6627442(grp)

CCAT:

101455828

BOD:

106616758

BDR:

105228772

RZE:	108367897 108374399

AOQ:

129249321

ALUD:

128863966

TDA:

119688010

MDE:	101887980 101891848

SCAC:

106082767

LCQ:

111687874

LSQ:

119608965

CVJ:	135951413(grp)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ005290

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108723104(grp)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139106305(Grp)

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:	105679793(grp)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141528976(Grp)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124213203(grp)

NFB:

NLO:

NVG:

AROA:

TMOL:

138125504(grp)

DPA:

109543242

ESIM:

136410002(grp)

EFOR:

136343445(grp)

SOY:

115884493

RFG:	143192040(grp)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209439

MJU:

VCD:

PMAC:

PXU:

BPHI:

137932848(grp)

PRAP:

111003679

ZCE:	119834269 119834698

LSIN:

AAGE:

HZE:

TNL:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

CFEL:

113375207 113375955 113375956

CCRN:

123291117

API:	100167829 100168998

DNX:	107161441 107166946

AGS:	114132433 114132783

RMD:	113552906 113556596

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106678732(grp)

NLU:

111063362

LDA:	142326181(grp)

HVI:

124356593

MQU:	128985485 128986913

PHU:	Phum_PHUM346290

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138709012(grp)

SGRE:

126278957

BROR:

134538519

IEL:

124157720

HAMR:

139700072(grp)

FCD:

110845196

DPX:	DAPPUDRAFT_43327

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123763230(grp)

CQD:	128697016(grp)

PTRU:

123503473

ESN:

127003056

MNZ:

135205280

MRJ:	136855903(grp)

PORN:

139754208(grp)

HAZT:

108670354

OOT:

143017859 143017863 143017911 143017913 143017914 143017915 143017916 143017917 143017918 143017919 143017921 143018287 143018502 143018511 143018518 143019048 143019051 143019052 143019094 143019128 143019316 143019786 143019787 143019790 143019793 143019794 143019800 143019801 143019802 143019813 143020228 143020515 143021152 143021156 143021357 143021606 143022010 143022011 143022023 143022031 143022034 143022276 143022472 143022474 143022525 143023360 143023759 143024043 143024044 143024046 143024106 143024126 143024136 143024333 143024459 143024460 143024463 143024465 143024472 143024473 143024474 143024476 143024477 143024871(grp) 143025661 143025697 143025782 143026054 143026056 143027294 143027302 143027338 143027339 143028022 143028023 143028024 143028025 143028052 143028059 143028091 143028093 143028115 143028931 143028933 143028934 143028938 143028940 143028941 143028943 143028944 143028945 143028946 143028947 143028948 143028949 143028950 143028952 143029277 143029282 143029290 143029298 143029303 143029309 143029314 143029319 143029335 143029351 143029367 143029383 143029415 143029431 143029451 143029461 143029470 143029488 143029493 143029502 143029509 143029517 143029526 143029626 143029637 143029649 143029653 143030182 143030183 143032199 143032513 143032516 143032517 143032518 143032541 143032605 143032606 143032607 143033070 143033075 143033076 143033077 143033078 143033083 143033084 143033085 143033086 143033087 143033088 143033110 143033593 143033599 143033664 143034302 143034663 143034866 143035998 143036001 143036002 143036013 143036020 143036021 143036022 143036025 143036027 143036033 143036058 143036127 143036172 143036173 143036184 143036185 143036277 143036278 143036288 143036294 143036301 143036319 143036321 143036324 143036326 143036329 143036331 143036333 143036338 143036341 143036342 143036343 143036344 143036347 143036350 143036358 143036652 143036993 143037032 143037041 143037042 143037043 143037044 143037045 143037046 143037160 143037162 143037753 143038233 143038289 143038290 143038295 143038296 143038297 143038299 143038304 143038329 143038330 143038331 143039311 143039798 143039828 143040205 143041253 143041254 143041255 143041293

EAF:	111697548 111714424

LSM:

121114857

TCF:

131884332

PPOI:

119094268

DSV:	119456143 119456145

DALB:

135898372(grp)

RSAN:

RMP:

VDE:

VJA:

GOE:

DPTE:

DFR:	124489978 124493819

CSCU:

111620828

CVS:	136975935(grp)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_Y39H10A.7(chk-1)

CBR:	CBG_06670(Cbr-chk-1) CBG_10679

CRQ:	GCK72_007516 GCK72_007517 GCK72_019159

NAI:	NECAME_09582

LOA:	LOAG_12066

TSP:

Tsp_05158

HRO:	HELRODRAFT_189278

LGI:	LOTGIDRAFT_173967

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_077180

SHX:	MS3_00004470(CHEK1)

LLON:

135495982

NVE:	5501525 5502980

EPA:

110232258

ATEN:

116303765

ADF:	107336044 107355729

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_24287

AQU:

100640078

SCE:	YBR274W(CHK1)

SEUB:

DI49_1298

SPAO:

SPAR_B03700

AGO:	AGOS_AEL185C

ERC:

Ecym_6307

KLA:	KLLA0_F01276g

KMX:	KLMA_50053(CHK1)

LTH:	KLTH0H10318g

VPO:	Kpol_1035p17

ZRO:	ZYRO0B09196g

CGR:	2888933(GVI51_I09361)

NCS:	NCAS_0B07380(NCAS0B07380)

NDI:	NDAI_0B04700(NDAI0B04700)

TPF:	TPHA_0O01400(TPHA0O01400)

TGB:	HG536_0F02180

TDL:	TDEL_0D02040(TDEL0D02040)

KAF:	KAFR_0C04280(KAFR0C04280)

KNG:	KNAG_0C01820(KNAG0C01820)

ZMK:	HG535_0C04790

SLUD:

SCDLUD_003576

DHA:	DEHA2C08272g

PIC:	PICST_33177(CHK1)

PPA:	PAS_chr4_0585

PKZ:	C5L36_0B06200

BNN:	FOA43_003336

BBRX:

BRETT_004182

OPA:	HPODL_02468

SLB:	AWJ20_2911(CHK1)

NCR:	NCU08346(un-1)

NTE:	NEUTE1DRAFT114358(NEUTE1DRAFT_114358)

SMP:	10810403(SMAC4_01615)

PAN:	PODANSg09646

PBEL:

QC761_103950(chk1)

PPSD:

QC762_103950(chk1)

PPSP:

QC763_103950(chk1)

PPSA:

QC764_103950(chk1)

TTT:	THITE_2121159

MTM:	MYCTH_2294445

CTHR:

CTHT_0059160

RTHE:

98124540(VTJ83DRAFT_351)

MGR:

MGG_03729

PPEI:

PpBr36_05592

PGRI:

PgNI_00261

TMN:	UCRPA7_3639

SSCK:

SPSK_04135

FGR:	FGSG_01506

FPU:	FPSE_05009

FPOA:

FPOAC1_001616

FVN:	FVRRES_01825

FVR:	FVEG_09569

FOX:	FOXG_11222

NHE:	NECHADRAFT_29794

FFC:	NCS54_00034600

FKR:	NCS57_00032700

FMU:	J7337_000394

TRE:	TRIREDRAFT_78309

TRR:	M419DRAFT_94781

TATV:

25786232(TrAtP1_006010)

TASP:

36617061(TrAFT101_005314)

MAW:	19251924(chk1)

MAJ:

MAA_00521

MBRN:

26242721(chk1)

PCHM:

VFPPC_01168

UVI:	66066246(UV8b_05469)

CMT:

CCM_05529

AMUS:

LMH87_005970

PLJ:	28891115(PLICBS_004573)

PTKZ:

JDV02_009433(chk1)

DCON:

63719209(DCS_06566)

VAL:	VDBG_03742

VDA:	VDAG_00976

CFJ:	CFIO01_11006

CLUP:

CLUP02_13958

CHIG:

CH63R_05995

CDET:

87948984(CDEST_12484)

ELA:	UCREL1_9719

PFY:	PFICI_13672

SSL:	SS1G_12179

BFU:	BCIN_05g06110(Bcchk1)

MBE:

MBM_03411

PSCO:

LY89DRAFT_703354

GLZ:	GLAREA_08424

ANI:	ANIA_05494

AFM:	AFUA_6G13160

ACT:	ACLA_086410

NFI:	NFIA_059080

AOR:	AO090003000441

ANG:	An08g10320

AFV:	AFLA_001250

ALUC:

AKAW2_51828S(CHK1)

ACHE:

ACHE_10546A(CHK1)

APUU:

APUU_40831A(CHK1)

PCS:	N7525_005968

PDP:	PDIP_45050

POU:	POX_a01816

TMF:	EYB26_003859

TRG:	TRUGW13939_10504

CIM:	CIMG_01668

CPW:	9691057(CHK1)

URE:	UREG_05390

ABE:

ARB_07449

TVE:

TRV_03991

PBL:	PAAG_04978

PBN:	PADG_04831

BGH:	BDBG_03611

PNO:	SNOG_05179

PTE:

PTT_09831

PTRR:

6342420(PtrM4_090710)

BZE:	COCCADRAFT_4193

BSC:	COCSADRAFT_126193

BOR:	COCMIDRAFT_27857

AALT:

CC77DRAFT_993861

ADAC:

96084355(ACET3X_004033)

ARAB:

EKO05_0007208

ZTR:	MYCGRDRAFT_64195

PFJ:	MYCFIDRAFT_202945

FFU:	CLAFUR5_13969

CBET:

CB0940_04954

BCOM:

BAUCODRAFT_436646

NPA:	UCRNP2_9008

TML:	GSTUM_00001636001

SPO:	2539087(chk1)

SOM:	SOMG_03044(chk1)

CNE:

CNG04000

CNB:

CNBG0730

CNG:	CNAG_03167

CGI:	CGB_G1060W

CDEU:

CNBG_2417

CDEC:

89989752(IAS62_002979)

CTEG:

91990938(I308_104082)

CBAS:

91985150(I312_105105)

CDEP:

91089408(L203_105199)

KMG:	30163672(I203_102885)

KNE:	92182323(IAR55_005065)

KDJ:	28970866(I303_108509)

KBI:	30212460(I302_108920)

KPIN:

30174303(I206_107601)

KSH:	87958866(IL334_006736)

KER:	91101055(V865_002251)

KSN:	43591475(CI109_104833)

KEP:	91098489(L201_007821)

TMS:	TREMEDRAFT_27276

TASA:

A1Q1_03668

CCAC:

CcaHIS019_0404340(chk1)

TVS:	TRAVEDRAFT_66216

DSQ:	DICSQDRAFT_86244

PCO:	PHACADRAFT_175408

SHS:	STEHIDRAFT_82972

HIR:	HETIRDRAFT_331300

PSQ:	PUNSTDRAFT_107114

ADL:	AURDEDRAFT_79137

FME:	FOMMEDRAFT_16344

GTR:	GLOTRDRAFT_48573

RSX:	RhiXN_00514

LBC:	LACBIDRAFT_304059

CCI:	CC1G_02812

ABP:	AGABI1DRAFT122426(AGABI1DRAFT_122426) AGABI1DRAFT132921(AGABI1DRAFT_132921)

ABV:	AGABI2DRAFT120023(AGABI2DRAFT_120023) AGABI2DRAFT122240(AGABI2DRAFT_122240)

PCUB:

JR316_0001487

MRR:	Moror_10767

E1B28_002201 E1B28_005677

CPUT:

CONPUDRAFT_113983

SLA:	SERLADRAFT_453634

UMA:	UMAG_11087

PFP:	PFL1_02244

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_00714

PTRC:

PtA15_1A599

PSTR:

Pst134EA_000319

MLR:	MELLADRAFT_102390

ECU:	ECU03_0620

EHE:	EHEL_030530

NCE:	NCER_101336

VNX:	VNE69_10075

MBR:	MONBRDRAFT_25225

SRE:	PTSG_00462

» show all

Reference

PMID:18451105

Authors

Yang XH, Shiotani B, Classon M, Zou L

Title

Chk1 and Claspin potentiate PCNA ubiquitination.

Journal

Genes Dev 22:1147-52 (2008)
DOI:10.1101/gad.1632808

Sequence

[hsa:1111]

Reference

PMID:18566216

Authors

Huang M, Miao ZH, Zhu H, Cai YJ, Lu W, Ding J

Title

Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins.

Journal

Mol Cancer Ther 7:1440-9 (2008)
DOI:10.1158/1535-7163.MCT-07-2116

Sequence

[hsa:1111]

Reference

PMID:9278511

Authors

Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ

Title

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.

Journal

Science 277:1497-501 (1997)
DOI:10.1126/science.277.5331.1497

Sequence

[hsa:1111]

LinkDB

DBGET integrated database retrieval system