Mus musculus (house mouse): 13077
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Entry
13077 CDS
T01002
Symbol
Cyp1a2, CP12, CYPIA2, P450-3
Name
(RefSeq) cytochrome P450, family 1, subfamily a, polypeptide 2
KO
K07409
cytochrome P450 family 1 subfamily A2 [EC:
1.14.14.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00140
Steroid hormone biosynthesis
mmu00232
Caffeine metabolism
mmu00380
Tryptophan metabolism
mmu00591
Linoleic acid metabolism
mmu00830
Retinol metabolism
mmu00980
Metabolism of xenobiotics by cytochrome P450
mmu00982
Drug metabolism - cytochrome P450
mmu01100
Metabolic pathways
mmu05204
Chemical carcinogenesis - DNA adducts
mmu05207
Chemical carcinogenesis - receptor activation
mmu05208
Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
13077 (Cyp1a2)
00591 Linoleic acid metabolism
13077 (Cyp1a2)
09105 Amino acid metabolism
00380 Tryptophan metabolism
13077 (Cyp1a2)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
13077 (Cyp1a2)
09110 Biosynthesis of other secondary metabolites
00232 Caffeine metabolism
13077 (Cyp1a2)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
13077 (Cyp1a2)
00982 Drug metabolism - cytochrome P450
13077 (Cyp1a2)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
13077 (Cyp1a2)
05207 Chemical carcinogenesis - receptor activation
13077 (Cyp1a2)
05208 Chemical carcinogenesis - reactive oxygen species
13077 (Cyp1a2)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
mmu00199
]
13077 (Cyp1a2)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.1 unspecific monooxygenase
13077 (Cyp1a2)
Cytochrome P450 [BR:
mmu00199
]
Cytochrome P450, animal type
CYP1 family
13077 (Cyp1a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
Sec8_N
COG7
Motif
Other DBs
NCBI-GeneID:
13077
NCBI-ProteinID:
NP_034123
MGI:
88589
Ensembl:
ENSMUSG00000032310
UniProt:
P00186
B6VGH4
LinkDB
All DBs
Position
9:complement(57584220..57590938)
Genome browser
AA seq
513 aa
AA seq
DB search
MAFSQYISLAPELLLATAIFCLVFWMVRASRTQVPKGLKNPPGPWGLPFIGHMLTVGKNP
HLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGK
SMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYLEEHVSKEANHLVSKLQKAMA
EVGHFEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPV
LRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQDFNKNSIQDITSALFKHSENYKDNGGLI
PEEKIVNIVNDIFGAGFDTVTTAITWSILLLVTWPNVQRKIHEELDTVVGRDRQPRLSDR
PQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKERCIYINQWQVNHDEKQWK
DPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLQHLEFS
VPPGVKVDLTPNYGLTMKPGTCEHVQAWPRFSK
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atggcgttctcccagtacatctccttagccccagagctgctactggccactgccatcttc
tgtttagtgttctggatggtcagagcctcaaggacccaggttcccaaaggcctgaagaat
ccacccggaccctggggcttgcccttcattgggcacatgctgactgtggggaagaaccca
cacctgtcactgacacggctgagtcagcagtatggggacgtgctgcagatccgcatcggc
tccactcctgtggtggtgctgagcggcctgaacaccatcaagcaggccctggtgaggcag
ggagatgacttcaagggccgaccagacctctacagcttcacacttatcactaacggcaag
agcatgactttcaacccagactctggacccgtgtgggctgcccgccggcgcctggcccag
gatgccctgaagagcttctccatagcctcggacccgacgtcagcatcctcttgctatttg
gaggagcacgtgagcaaggaggctaaccatctcgtcagcaagcttcagaaggcgatggca
gaggttggccacttcgaaccagtcagccaggtggtggaatcggtggctaacgtcattggt
gccatgtgctttgggaagaacttcccccggaagagcgaggagatgctgaacatcgtgaat
aacagcaaggactttgtggagaatgtcacctcagggaatgcagtggacttcttcccggtc
ctgcgctacctgcccaacccggccctcaagaggtttaagaccttcaatgataacttcgtg
ctgtttctgcagaaaactgtccaggagcactaccaagacttcaacaagaacagtatccaa
gacatcacaagtgccctgttcaagcacagcgagaactacaaagacaatggcggtctcatc
cccgaggagaagattgtcaacattgtcaatgacatctttggagctggctttgacacagtc
accacagccatcacctggagcattttgctacttgtgacatggcctaacgtgcagaggaag
atccatgaggagctggacacggtggttggcagggatcggcaaccacggctttctgaccgt
ccccagctgccatatctagaggccttcatcctggagatctaccgatacacatcctttgtc
cccttcaccatcccccacagcacaacgagggacacctcactgaatggcttccacattccc
aaggagcgctgtatctacataaaccagtggcaggtcaaccatgatgagaagcagtggaaa
gacccctttgtgttccgcccagagcggtttcttaccaataacaactcggccatcgacaag
acccagagcgagaaggtgatgctcttcggcttgggaaagcgccggtgcattggggagatc
ccggccaagtgggaagtcttcctcttcttagccatcctgctgcagcatctggagtttagt
gtgccaccgggtgtgaaggtggacctgacacccaactatgggttgaccatgaagcccggg
acctgtgaacacgtccaggcatggccacgcttttccaagtga
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