Mus musculus (house mouse): 13869
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Entry
13869 CDS
T01002
Symbol
Erbb4, Her4, c-erbB-4
Name
(RefSeq) erb-b2 receptor tyrosine kinase 4
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04020
Calcium signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu05014
Amyotrophic lateral sclerosis
mmu05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
13869 (Erbb4)
04012 ErbB signaling pathway
13869 (Erbb4)
04020 Calcium signaling pathway
13869 (Erbb4)
04151 PI3K-Akt signaling pathway
13869 (Erbb4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
13869 (Erbb4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
13869 (Erbb4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
13869 (Erbb4)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
13869 (Erbb4)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
13869 (Erbb4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
13869
NCBI-ProteinID:
NP_034284
MGI:
104771
Ensembl:
ENSMUSG00000062209
UniProt:
Q61527
LinkDB
All DBs
Position
1:complement(68071063..69147756)
Genome browser
AA seq
1292 aa
AA seq
DB search
MKLATGLWVWGSLLMAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYD
GEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRTRIDSNRNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQG
ATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHD
KPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFANAL
GSAEYMKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRP
IVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
atgaagctggcgacgggactctgggtctgggggagccttctgatggcagcggggaccgtc
cagcccagcgcttctcagtcagtgtgcgcaggaacagagaacaaactgagctctctctct
gacctggaacagcagtaccgagccttgcgcaaatactatgaaaactgcgaggtagtcatg
ggcaacctggagatcaccagcatcgagcacaaccgggacctctccttcctgcggtctatc
cgagaagtcacaggctacgtcctggtggccctcaaccagtttcgttacttgcctctggag
aatttacgcattattcgtgggacaaaactatatgaagatcgctatgccttagcgatattc
ttaaactacaggaaagatggcaactttggactccaagaacttggattaaagaacctgacc
gaaatactaaatggtggagtctatgtagaccagaacaaattcctatgttatgctgacact
atacactggcaagatattgttcggaatccatggccttccaacatgactctggtgtcaaca
aatggaagttctggatgtggaagatgccataagtcttgcactggccgatgctggggaccc
acagaaaatcactgccagaccttgaccagaactgtgtgtgctgaacaatgtgatggcagg
tgctatggaccctacgttagtgactgctgccatcgagaatgtgctggaggctgctcagga
ccaaaggacactgactgctttgcctgcatgaacttcaatgacagtggagcctgcgttact
caatgtccccaaacatttgtctacaatccaaccacctttcaactggaacacaacttcaat
gcaaagtacacgtatggagcattctgtgttaagaaatgtccacataacttcgtggtagat
tccagttcttgtgtacgagcctgccctagttctaagatggaagtagaagaaaatgggatt
aaaatgtgtaagccttgcaccgatatttgccccaaagcatgtgatggaatcggcacggga
tcactgatgtctgctcagactgtggattcaagtaacattgacaaattcataaactgcaca
aagatcaatggcaatctcatctttcttgtcactggcattcatggagacccttacaatgct
attgacgccatagatccagagaaactgaatgtctttcggactgtcagagaaataacaggt
ttcctgaacatacagtcttggcccccaaatatgacagatttcagtgttttctccaacctc
gtcacaattggaggaagagtcctctacagtggtctctcattgctgatcctcaaacaacaa
ggtatcacttccctacagttccagtctctgaaggaaatcagtgcgggcaatatctacatc
actgacaacagcaacctgtgttattaccataccattaactggacaacactcttcagcacc
attaaccagagaatagtgatccgagataacagaagagctgagaattgtactgctgaaggc
atggtatgcaaccacctgtgttcaaatgatggttgttggggacctgggccggaccagtgc
ctgtcatgtcggcgcttcagcaggggaaagatctgcatagagtcttgcaacctttatgat
ggggaatttcgagagtttgaaaacggctccatctgtgttgagtgtgactcccagtgtgag
aaaatggaagatggactcctcacatgccatggaccgggacctgacaactgcacaaagtgc
tctcattttaaggatggtccaaactgtgtggagaaatgtccagatggcctacagggagca
aacagtttcatttttaagtatgcagatcaggatcgggagtgccacccttgccatccaaac
tgcacccaggggtgtaacggtcccactagtcatgactgcatttactacccatggacgggc
cattccactttaccacaacacgctagaactccactgattgcagccggagtcattggaggc
ctcttcatcctggtgatcatggctttgacatttgctgtctatgtcagaagaaagagcatc
aaaaagaaacgtgctttgaggagattcctggagacagagctggtagagcccttaactccc
agtggcacggcacccaatcaagctcaacttcgcattttgaaggaaaccgaactaaagagg
gtaaaggtccttggctcgggagcttttggaaccgtttataaaggtatttgggtgcctgaa
ggtgaaacagtgaaaatccctgtggctataaagatcctcaatgaaacaactggccccaaa
gccaacgtggagttcatggatgaggctctgatcatggcaagtatggatcacccacaccta
gttcgcctattgggagtgtgtctgagtcccactatccagttggttacgcagctgatgccg
catggctgcctactggactatgttcatgaacacaaggataacattggatcacagctgctg
ttgaactggtgtgtccagattgctaagggaatgatgtacctagaagaaagacggcttgtt
catcgggatctggcagcccgcaatgtcttagtgaaatctccaaatcatgttaaaatcaca
gattttggactggcccggctcttggaaggagatgaaaaagaatacaatgctgatggtggc
aagatgccaattaaatggatggctctggaatgtatacattataggaaattcacacatcaa
agtgatgtttggagctatggcgtcactatatgggaactgatgacctttggaggaaagccc
tatgatggaattccaacccgagaaatccccgatttactggagaaaggagagcgtctgcct
cagcctcccatctgcactattgatgtttacatggtcatggtcaaatgttggatgatcgat
gctgacagcagacctaaattcaaagaactggctgctgagttttcaagaatggctagagac
cctcaaagatacctagttattcagggtgatgatcgtatgaagcttcccagtccaaatgac
agcaaattcttccagaatctcttggatgaagaggatttggaagacatgatggatgctgag
gaatatttggtcccccaggctttcaacatacctcctcccatctacacatccagaacaaga
attgactccaataggaatcagtttgtgtaccaagatgggggctttgctacacaacaagga
atgcccatgccctacagagccacaaccagcaccataccagaggctccagtagctcagggt
gcaacggctgagatgtttgatgactcctgctgtaatggtaccctacgaaagccagtggca
ccccatgtccaagaggacagtagcactcagaggtatagtgctgatcccacagtgttcgcc
ccagaacggaatcctcgaggagaactggatgaagaaggctacatgactccaatgcatgac
aagcccaaacaagaatatctgaatcctgtggaagagaacccttttgtgtcccgaaggaag
aatggagatcttcaagctttagataatccggagtatcacagtgcttccagcggtccaccc
aaggcggaggatgaatacgtgaatgagcctctatacctcaacaccttcgccaatgccttg
gggagtgcagagtacatgaaaaacagtgtactgtctgtgccagagaaagccaagaaagca
tttgacaaccccgactactggaaccacagcctgccaccccggagcacccttcagcaccca
gactacctgcaggaatacagcacaaaatatttttataaacagaatggacggatccgcccc
attgtggcagagaatcctgagtacctctcggagttctcgctgaagcctggcactatgctg
ccccctccgccctacagacaccggaatactgtggtgtga
DBGET
integrated database retrieval system
