Mus musculus (house mouse): 15360
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Entry
15360 CDS
T01002
Symbol
Hmgcs2, 1300002P16, mHS
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00280
Valine, leucine and isoleucine degradation
mmu00650
Butanoate metabolism
mmu00900
Terpenoid backbone biosynthesis
mmu01100
Metabolic pathways
mmu03320
PPAR signaling pathway
Module
mmu_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
15360 (Hmgcs2)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
15360 (Hmgcs2)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
15360 (Hmgcs2)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
15360 (Hmgcs2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
15360 (Hmgcs2)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III
HRDE1_NRDE3_N
Motif
Other DBs
NCBI-GeneID:
15360
NCBI-ProteinID:
NP_032282
MGI:
101939
Ensembl:
ENSMUSG00000027875
UniProt:
P54869
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Position
3:98187747..98218054
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AA seq
508 aa
AA seq
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MQRLLAPARRVLQVKRAMQETSLTPAHLLSAAQQRFSTIPPAPLAKTDTWPKDVGILALE
VYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLP
WDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWM
ESSYWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLVLEQGLRGTHMENAYD
FYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRKKIQNQWKQAGNNQPFTLDDVQYMIF
HTPFCKMVQKSLARLMFNDFLSSSSDKQNNLYKGLEAFRGLKLEETYTNKDVDKALLKAS
LDMFNQKTKASLYLSTNNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASF
FSFRVSKDASPGSPLEKLVSSVSDLPKRLDSRRRMSPEEFTEIMNQREQFYHKVNFSPPG
DTSNLFPGTWYLERVDEMHRRKYARCPV
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgcagcggcttttggctccagcgaggcgggtcctgcaagtgaagagagcgatgcaggaa
acttcgctcacacctgctcacctgctctcagcagcccagcagaggttttctacaatccct
cctgctcccctggccaaaacagatacatggccaaaagatgtgggcatccttgccctggag
gtctattttccagcccaatatgtggaccaaactgacctggaaaagttcaacaatgtggaa
gcagggaagtatacagtgggcttgggccagacccgtatgggcttctgttcagtccaggag
gacatcaactccctgtgcctgacagtggtacagaggctgatggaacgcacaaagctgccg
tgggatgctgtgggccgtctggaagtgggcaccgagaccatcattgacaagtccaaggct
gtcaaaacagtgctcatggaactgttccaggattcaggcaacactgacatcgagggcata
gataccaccaacgcctgttatggcggcacagcctccctcttcaatgctgccaactggatg
gagtccagctactgggatggtcgctatgccctggtggtctgtggtgacattgcagtctac
ccgagtggtaacgcccgccccacaggtggtgctggggctgtggcaatgctgatcgggccc
aaggcccctctggtcctcgagcaagggctgaggggaactcacatggagaacgcgtacgac
ttctacaaaccaaacttggcctcagagtatccactggtggatgggaagctgtctatccag
tgctacctgcgggccttggatcgatgctatgcagcctaccgcaagaagatccagaatcag
tggaagcaagctggaaacaaccagcctttcaccctcgatgatgtgcagtatatgatcttc
cacacacccttttgcaagatggtccagaaatccctggctcggttgatgttcaatgacttc
ctgtcatccagcagtgacaaacagaacaacttatacaagggcctagaggccttcaggggt
ctaaagctggaagaaacctacaccaacaaggatgtagacaaggctcttttgaaggcctcc
ctggacatgttcaaccagaagaccaaggcctccctttacctctccacaaataatgggaac
atgtacacctcttccctctatggctgcctggcctcacttctctctcaccactctgcccaa
gaattggctggctccaggattggagccttctcctacggctcaggcttagcagcaagtttc
ttttcattccgagtgtccaaggatgcttccccaggttcccccctggagaaactggtgtct
agtgtgtcagatctgcccaaacgtctagactcccggagacgcatgtcccctgaggaattc
acagaaataatgaaccagagagagcaattttaccacaaggtgaacttctctccacctgga
gacacaagcaatctcttcccaggtacttggtaccttgaacgagtggatgagatgcatcgc
aggaagtatgcccggtgtcccgtctaa
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