Mus musculus (house mouse): 15925
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Entry
15925 CDS
T01002
Symbol
Ide, 1300012G03Rik, 4833415K22Rik
Name
(RefSeq) insulin degrading enzyme
KO
K01408
insulysin [EC:
3.4.24.56
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu03266
Virion - Herpesvirus
mmu05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03266 Virion - Herpesvirus
15925 (Ide)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
15925 (Ide)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
15925 (Ide)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.56 insulysin
15925 (Ide)
Peptidases and inhibitors [BR:
mmu01002
]
Metallo peptidases
Family M16: pitrilysin family
15925 (Ide)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M16_M
Peptidase_M16_C
Peptidase_M16
DUF6702
Motif
Other DBs
NCBI-GeneID:
15925
NCBI-ProteinID:
NP_112419
MGI:
96412
Ensembl:
ENSMUSG00000056999
UniProt:
Q8CGB9
LinkDB
All DBs
Position
19:complement(37246140..37341664)
Genome browser
AA seq
1019 aa
AA seq
DB search
MRNGLVWLLHPALPGTLRSILGARPPPAKRLCGFPKQTYSTMSNPAIQRIEDQIVKSPED
KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKD
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREE
LLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLRQ
LYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGKLHYYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAI
VSKSFEGKTDRTEQWYGTQYKQEAIPEDIIQKWQNADLNGKFKLPTKNEFIPTNFEILSL
EKDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFEIDKKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNITKQAALGVMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNYDRDNIEVAYLKTLTKDDIIRFYQEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgcggaacgggctcgtgtggctgctgcaccccgcgctgcccggcaccttgcgctccatc
ctcggcgcccgcccgccgcccgcgaagcgactgtgtggattcccaaaacagacttacagc
acaatgagtaatccggccatccagagaatagaagaccaaattgtcaagtctcctgaagac
aaacgggaataccgtggactagagctggccaatggcatcaaagtgcttctcatcagcgat
cccaccacagacaagtcctcagcggccctcgatgtgcacataggttcactgtcagaccct
ccaaatattcctggcttaagtcatttttgtgaacatatgctgtttttgggaaccaagaaa
tatcctaaagaaaatgaatatagccagtttctcagtgaacatgctggaagttcaaatgca
ttcaccagtggagaacacaccaattattatttcgatgtttcccatgaacacttggaagga
gccctggacaggtttgcgcagtttttcctgtgccccttgtttgatgcaagttgtaaagac
agagaggtgaacgctgtcgattcagaacatgagaagaatgtgatgaacgatgcctggaga
ctcttccagctggaaaaggctacggggaaccccaaacaccccttcagcaaatttgggaca
ggaaacaaatatactctagagactcggcccaaccaagaaggcatcgacgtaagggaagag
ctcttgaaatttcactctacgtattattcgtccaatctgatggcgatttgtgttttaggt
cgagaatccttagacgacctcactaacctggtggtgaagctgttctccgaggtggagaac
aagaacgttcctctgcctgagttccctgagcaccctttccaggaagagcatctcaggcaa
ctttataaaatagtacccattaaggatattagaaatctttatgtgacatttcccatacca
gaccttcagcagtactacaaatccaatcctggtcattatcttggtcatctaattgggcac
gaaggtcctggaagcctgttgtcagaactcaaatcaaagggctgggtgaataccctggtt
ggtggacagaaggaaggagcccgaggttttatgttttttatcattaatgtggacttaact
gaagaagggttattgcacgttgaagatataattttgcacatgtttcaatacattcagaag
ctacgtgcagaaggacctcaagaatgggttttccaagagtgcaaggacttgaatgctgtt
gctttcagatttaaagataaagagagaccacgaggctatacgtccaagattgcaggaaag
ttgcactattatcccctaaatggagtgctcacagctgaatatctattggaggaatttaga
cccgacttgatagacatggttcttgataaactcagaccagaaaatgtgcgggtggcaata
gtttccaaatcatttgaagggaaaactgaccgcacagagcagtggtatggaacacagtat
aagcaagaagctatcccagaggacatcattcagaaatggcaaaatgctgaccttaatgga
aaatttaagcttccaacaaagaatgaatttattcccacaaattttgagattttgtcatta
gaaaaagatgcaacaccataccctgctcttattaaggatacagccatgagtaagctgtgg
ttcaaacaagatgataaatttttcttgccgaaagcttgtctcaactttgaatttttcagc
ccgtttgcttatgtggaccccttgcactgtaacatggcctatttgtaccttgagctcctc
aaagactcactcaacgagtatgcatatgcagcagagctagcaggcctgagctatgacctc
caaaataccatctatgggatgtatctctcagtgaaaggttacaatgacaaacagccaatt
ttgctgaagaagatcaccgagaaaatggctacttttgagattgataagaagagatttgaa
attatcaaagaggcctatatgcgatctcttaataacttccgggctgagcagcctcaccag
catgccatgtactacctccgcttgctgatgactgaagtggcctggactaaagatgagcta
aaagaagcccttgacgatgttaccctcccccgacttaaggccttcatacctcagctgctg
tcacggctgcatattgaagcacttctccatggaaacataaccaagcaggctgccttagga
gttatgcagatggtagaagacactcttatcgagcatgctcacaccaaacctctccttcca
agtcagctagtccggtacagagaagtccagctccctgacagaggatggtttgtttatcag
cagaggaatgaagttcacaataactgcggcatcgagatctactaccagacagacatgcag
agcacctcggagaacatgttcctggagctgttttgccagattatctcggagccttgcttc
aataccctgcgcaccaaggagcagcttggctatattgtcttcagtggaccccgtcgggcc
aacggtatccaaggcttgcgcttcatcatccagtcagaaaaaccaccccactacctggag
agcagagtagaagccttcttgattaccatggaaaaggccatagaggacatgacagaggag
gcgttccaaaaacacattcaagcactagcgattcggcgactcgacaaaccaaagaaactc
tctgcggagtgtgctaaatactggggggaaatcatctcgcagcagtacaattacgacaga
gataacatagaagttgcatatttaaagacacttaccaaggacgatatcatcagattctac
caggaaatgttggctgtcgacgcaccgaggagacataaagtgtctgtccatgttcttgcc
agggaaatggattcttgtcctgttgttggagagttcccctctcagaatgatataaacttg
tccgaagcgccacccttgccacaacctgaagtgattcacaacatgactgagttcaagcgt
ggcctgccactgtttcccctcgtgaaaccacatattaacttcatggctgcaaaactctga
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