Mus musculus (house mouse): 16801
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Entry
16801 CDS
T01002
Symbol
Arhgef1, Lbcl2, Lsc
Name
(RefSeq) Rho guanine nucleotide exchange factor 1
KO
K12330
Rho guanine nucleotide exchange factor 1
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04270
Vascular smooth muscle contraction
mmu04611
Platelet activation
mmu04810
Regulation of actin cytoskeleton
mmu04928
Parathyroid hormone synthesis, secretion and action
mmu05135
Yersinia infection
mmu05163
Human cytomegalovirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
16801 (Arhgef1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
16801 (Arhgef1)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
16801 (Arhgef1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
16801 (Arhgef1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
16801 (Arhgef1)
05205 Proteoglycans in cancer
16801 (Arhgef1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
16801 (Arhgef1)
09171 Infectious disease: bacterial
05135 Yersinia infection
16801 (Arhgef1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
16801 (Arhgef1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
16801 (Arhgef1)
Membrane trafficking [BR:
mmu04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
16801 (Arhgef1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PH_13
SOS1_NGEF_PH
AbiJ_NTD3
SET_assoc
Motif
Other DBs
NCBI-GeneID:
16801
NCBI-ProteinID:
NP_001123624
MGI:
1353510
Ensembl:
ENSMUSG00000040940
UniProt:
Q61210
LinkDB
All DBs
Position
7:24601762..24626019
Genome browser
AA seq
920 aa
AA seq
DB search
MGEVAGGAAPGPPRSGLVSIIIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMAL
LQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPSVAFEL
DRTRPDLISEDVQRRFIQEVVQSQQAAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKD
RGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVRTKSGDKKSGR
NFFRKKVMGNRRSDEPPKTKKGLSSILDPARWNRGEPSAPDCRHLKVEADAEKPGPADRK
GGLGMSSRDRTVGTPGQDNPGVSLHPLSTDSVDSREPGVDTPQEPGDTPPQGPTSLEPLA
PPESTEDNGETESPEPGDDGEPGRSGLELEPEEPPGWRELVPPDTLLSLPKSQVKRQEVI
SELLVTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFPSLDELIEVHSLFLDRLMKR
RQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQ
EAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEESTERGKVELAAECCREILHH
VNQAVRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKD
KAIEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATD
HKAFYVIFTWDQEAQIYELVAQTSSERKNWCNLITETAGSLKVPAPASRLKPRPSPSSIR
EPLLSSSENGTGGAEMAPADARTERLLNDLLPFCRPGPEGQLAATALQKVLSLKQILLST
EEDSGAGPPRDGDGVPGGRAPGPVHTQEIEENLLSLEVAIRQLEELEEEFCRLRPLLSQL
GGTLSPNLAAPERSAQTGLS
NT seq
2763 nt
NT seq
+upstream
nt +downstream
nt
atgggagaagtcgccggaggggcggccccagggcctccccggtctggcctggtgtccatc
atcatcggggcggaggatgaggattttgagaacgagctggaggcgaactcagaagatcaa
aacagccagttccagagcctagagcaagtgaagcgccgccctgcccacctcatggccctc
ctgcagcatgtggccctgcagttcgagccaggaccactgctctgctgcctgcatgcagac
atgctgagctctctgggccccaaagaagccaagaaggccttccttgacttctatcacagt
ttcctggagaagactgcggttctacgggtgccggtccctcccagtgtcgcttttgaactt
gatcgtactcgacctgatctgatctctgaggatgtccagaggcggttcatacaagaggtg
gtgcagagccagcaggcagccgtgagccgtcagctagaggacttccgctccaagcggctc
atgggcatgacgccctgggagcaggaactgagcctgctggagccctggattgggaaagac
cgaggcaactatgaggcccgggagcggcatgttgcggagcggctgctgtcccacctggag
gagacccagcataccatctctacagatgaagagaaaagtgctgctgtggtcactgccatc
agcctgtatatgcgccaccttggagtccggaccaagagtggggacaagaagtcgggaagg
aacttcttccggaaaaaggtgatggggaatcggaggtcagacgaacccccaaagacaaag
aaagggctgagcagtatcctagatcctgcacgttggaaccggggagagccatccgctcca
gattgtcgacatctaaaggtcgaggctgatgcagagaagccaggccctgcagaccggaag
ggaggcctgggtatgtcttctcgggacaggactgttgggactcctggacaggacaaccca
ggagtctccctgcaccctctgtctacagacagcgtcgactcccgggaaccaggcgtggat
accccgcaggagccaggggatacacccccacagggccctaccagcctggagcccctggcg
cccccagagagcacagaggacaatggcgagactgagagccctgagcccggagatgatggg
gagccaggacggtcaggcctggaactggaaccagaagaacctcctgggtggagggaactc
gtgcccccagacaccctgctcagtctgcccaagagccaagtgaagcggcaagaggtcatc
agcgagctgctcgtgactgaggcagctcacgtgcgcatgctacgggtactgcatgacctc
ttctaccagcccatggcggatggaggcttcttccctctggacgagctgcagaacatcttc
ccgagcctggatgagctcatcgaggtgcactccctgttcctcgatcgcttgatgaagcgg
agacaagagagtggctacctcattgaggagatcggcgatgtgctactggcccggttcgat
ggtgctgagggctcatggttccagaagatctcctcccgcttctgcagccgccagtcgttc
gctctagagcagctcaaagccaagcagcgcaaggagcctcggttctgtgcctttgtgcag
gaagctgagagccgcccgagatgccggcgcctacagttaaaggacatgatccccactgag
atgcagcgactgaccaagtacccactgctgctacagagcatcgggcagaacacagaggag
tctacagaacgagggaaagtggagcttgcagctgagtgctgccgggagattctgcaccat
gtcaatcaagccgtccgtgacatggaggacctgctgcggctcaaggattaccagcggcgc
ctggacttgactcacctacggcagagcagtgaccctatgctgagcgagttcaagaacctg
gacatcactaagaagaagttggtccatgaaggccccctcacgtggcgagtgaccaaagac
aaagctatagaagtgcacgtgctcttgctggacgacctgctgctgctgctccagcgccag
gacgagaggctgctgctcaagtcccacagccggacgctgacacctacccccgatggcaag
accatgctgcggccggtgctccggctcacctctgccatgacccgagaggtggccactgat
cacaaagctttctacgtcatttttacctgggaccaggaggcccagatatatgagctggtg
gcacagacatcttcggaacgcaaaaactggtgtaacctcatcactgagactgctggatcc
ctgaaggtccctgcccctgcctcccgcctcaaaccccggcccagcccaagcagcatccga
gaacccctgctcagcagctctgagaatggcactggaggcgcagagatggctccagctgat
gccaggacagagcggctcctcaatgacctcctgcccttctgcagaccaggcccagagggc
cagcttgctgccacagcccttcagaaagtactgtccctgaagcagatcctgctaagcact
gaggaagacagtggagcggggcctccccgcgatggggatggggtgcctggtggtagggcc
cccggcccagtgcacacccaggagattgaggaaaacttgcttagcttagaggtggccatc
agacaactggaggagttggaagaggaattttgtcgcctaagacccctcctgtcccagctt
ggggggactctgtcccccaacctggctgcacctgaacgctctgctcagacaggcctttca
tga
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