Mus musculus (house mouse): 16818
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Entry
16818 CDS
T01002
Symbol
Lck, Hck-3, Lsk, Lskt, p56<lck>, p56Lck
Name
(RefSeq) proto-oncogene tyrosine-protein kinase LCK isoform b
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04064
NF-kappa B signaling pathway
mmu04380
Osteoclast differentiation
mmu04517
IgSF CAM signaling
mmu04650
Natural killer cell mediated cytotoxicity
mmu04658
Th1 and Th2 cell differentiation
mmu04659
Th17 cell differentiation
mmu04660
T cell receptor signaling pathway
mmu05135
Yersinia infection
mmu05166
Human T-cell leukemia virus 1 infection
mmu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mmu05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
16818 (Lck)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
16818 (Lck)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
16818 (Lck)
04660 T cell receptor signaling pathway
16818 (Lck)
04658 Th1 and Th2 cell differentiation
16818 (Lck)
04659 Th17 cell differentiation
16818 (Lck)
09158 Development and regeneration
04380 Osteoclast differentiation
16818 (Lck)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
16818 (Lck)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
16818 (Lck)
09171 Infectious disease: bacterial
05135 Yersinia infection
16818 (Lck)
09163 Immune disease
05340 Primary immunodeficiency
16818 (Lck)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
16818 (Lck)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
16818 (Lck)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
16818 (Lck)
Protein kinases [BR:
mmu01001
]
Non-receptor tyrosine kinases
SRC family
16818 (Lck)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
16818 (Lck)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
DUF7251
Haspin_kinase
SH3_16
Kdo
SH3_3
Motif
Other DBs
NCBI-GeneID:
16818
NCBI-ProteinID:
NP_001155905
MGI:
96756
Ensembl:
ENSMUSG00000000409
UniProt:
P06240
LinkDB
All DBs
Position
4:complement(129442142..129467415)
Genome browser
AA seq
509 aa
AA seq
DB search
MGCVCSSNPEDDWMENIDVCENCHYPIVPLDSKISLPIRNGSEVRDPLVTYEGSLPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHDLVRHYTNASDGLCTKLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHPRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFIEEQNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER
PEDRPTFDYLRSVLDDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgtctgcagctcaaaccctgaagatgactggatggagaacattgacgtgtgt
gaaaactgccactatcccatagtcccactggacagcaagatctcgctgcccatccggaat
ggctctgaagtgcgggacccactggtcacctatgagggatctctcccaccagcatccccg
ctgcaagacaacctggttatcgccctgcacagttatgagccctcccatgatggagacttg
ggctttgagaagggtgaacagctccgaatcctggagcagagcggtgagtggtggaaggct
cagtccctgacgactggccaagaaggcttcattcccttcaacttcgtggcgaaagcaaac
agcctggagcctgaaccttggttcttcaagaatctgagccgtaaggacgccgagcggcag
cttttggcgcccgggaacacgcatggatccttcctgatccgggaaagcgaaagcactgcg
gggtccttttccctgtcggtcagagacttcgaccagaaccagggagaagtggtgaaacat
tacaagatccgtaacctagacaacggtggcttctacatctcccctcgtatcacttttccc
ggattgcacgatctagtccgccattacaccaacgcctctgatgggctgtgcacaaagttg
agccgtccttgccagacccagaagccccagaaaccatggtgggaggacgaatgggaagtt
cccagggaaacactgaagttggtggagcggctgggagctggccagttcggggaagtgtgg
atggggtactacaacggacacacgaaggtggcggtgaagagtctgaaacaagggagcatg
tcccccgacgccttcctggctgaggctaacctcatgaagcagctgcagcacccgcggcta
gtccggctttatgcagtggtcacccaggaacccatctacatcatcacggaatacatggag
aacgggagcctagtagattttctcaagactccctcgggcatcaagttgaatgtcaacaaa
cttttggacatggcagcccagattgcagagggcatggcgttcatcgaagaacagaattac
atccatcgggacctgcgcgccgccaacatcctggtgtctgacacgctgagctgcaagatt
gcagactttggcctggcgcgcctcattgaggacaatgagtacacggcccgggagggggcc
aaatttcccattaagtggacagcaccagaagccattaactatgggaccttcaccatcaag
tcagacgtgtggtccttcgggatcttgcttacagagatcgtcacccacggtcgaatccct
tacccaggaatgaccaaccctgaagtcattcagaacctggagagaggctaccgcatggtg
agacctgacaactgtccggaagagctgtaccacctcatgatgctgtgctggaaggagcgc
ccagaggaccggcccacgtttgactaccttcggagtgttctggatgacttcttcacagcc
acagagggccagtaccagccccagccttga
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