Mus musculus (house mouse): 18479 Help Entry 18479             CDS       T01002                                  Symbol Pak1, PAK-1, Paka Name (RefSeq) p21 (RAC1) activated kinase 1   KO K04409   p21-activated kinase 1 [EC:2.7.11.1] Organism mmu  Mus musculus (house mouse) Pathway mmu04010   MAPK signaling pathway mmu04012   ErbB signaling pathway mmu04014   Ras signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04360   Axon guidance mmu04392   Hippo signaling pathway - multiple species mmu04510   Focal adhesion mmu04625   C-type lectin receptor signaling pathway mmu04650   Natural killer cell mediated cytotoxicity mmu04660   T cell receptor signaling pathway mmu04666   Fc gamma R-mediated phagocytosis mmu04810   Regulation of actin cytoskeleton mmu05132   Salmonella infection mmu05170   Human immunodeficiency virus 1 infection mmu05205   Proteoglycans in cancer mmu05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     18479 (Pak1)    04012 ErbB signaling pathway     18479 (Pak1)    04014 Ras signaling pathway     18479 (Pak1)    04392 Hippo signaling pathway - multiple species     18479 (Pak1)    04024 cAMP signaling pathway     18479 (Pak1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     18479 (Pak1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     18479 (Pak1)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     18479 (Pak1)    04650 Natural killer cell mediated cytotoxicity     18479 (Pak1)    04660 T cell receptor signaling pathway     18479 (Pak1)    04666 Fc gamma R-mediated phagocytosis     18479 (Pak1)    04062 Chemokine signaling pathway     18479 (Pak1)   09158 Development and regeneration    04360 Axon guidance     18479 (Pak1)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     18479 (Pak1)   09162 Cancer: specific types    05211 Renal cell carcinoma     18479 (Pak1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     18479 (Pak1)   09171 Infectious disease: bacterial    05132 Salmonella infection     18479 (Pak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmu01001]     18479 (Pak1)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmu04131]     18479 (Pak1)    03036 Chromosome and associated proteins [BR:mmu03036]     18479 (Pak1) Enzymes [BR:mmu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      18479 (Pak1) Protein kinases [BR:mmu01001]  Serine/threonine kinases: STE group   STE20 family    18479 (Pak1) Membrane trafficking [BR:mmu04131]  Exocytosis   Calcium ion-dependent exocytosis    Kinases and associated proteins     18479 (Pak1)  Endocytosis   Macropinocytosis    Kinases     18479 (Pak1) Chromosome and associated proteins [BR:mmu03036]  Eukaryotic type   Sister chromatid separation proteins    Aurora kinases     Regulators of Aurora kinases      18479 (Pak1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Motif Other DBs NCBI-GeneID:  18479 NCBI-ProteinID:  NP_001344291 MGI:  1339975 Ensembl:  ENSMUSG00000030774 LinkDB All DBs Position 7:97437748..97561588 Genome browser AA seq 552 aa AA seqDB search MSNNGVDIQDKPPAPPMRNTSTMIGAGSKDTGTLNHGSKPLPPNPEEKKKKDRFYRSILP GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD DDATPPPVIAPRPEHTKSFGQKDQREVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPD ALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATG QEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLT DVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQ ITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRAL YLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPL IAAAKEATKNNH NT seq 1659 nt NT seq  +upstreamnt  +downstreamnt atgtcaaataacggcgtagacatccaggacaaacccccagcccctccgatgagaaacacc agcactatgattggagccggcagcaaagacactggaaccctaaaccacggctccaaacct ctgcctccaaacccagaggagaagaaaaagaaggaccggttttatcgatccatcttacct ggagataaaacaaataaaaagaaggagaaggagcgaccagagatttctcttccttcagat tttgagcatacaattcatgttggttttgatgctgtcacaggggagtttacgggaatgcca gaacagtgggctcgcttgcttcaaacatcaaatatcacaaagtcagaacagaagaaaaac ccacaggctgttctggatgtgttggaattttataactctaagaagacctccaatagtcag aagtacatgagttttacagataagtcagctgaagattataattcttctaacactttgaat gtgaagactgtgtctgagaccccagcagtaccaccagtgtcagaagatgaagatgatgat gacgatgctaccccacctccagtgattgctccacgcccagaacacacaaaatcttttggg cagaaggatcagagagaggtatatacacgatctgtgattgaaccacttcctgttactcca actcgggatgtggctacatctcctatttctcctactgagaataacaccactccgccagat gctttgacccggaacacggaaaaacagaagaagaagcctaaaatgtctgatgaggagatc ttagagaaattacggagcatagtgagtgtgggtgatcctaagaagaagtacacacggttc gagaagattggacaaggtgcttcaggcacagtgtatactgcaatggatgtagccacaggg caggaggtggccattaaacagatgaatcttcagcagcagccgaagaaagagctgattatt aatgagatcctggtcatgagggaaaacaaaaacccaaatattgtcaactacctggacagt taccttgtgggagatgagctgtgggttgttatggaatacttggctggaggctccttgaca gatgtggtgacagaaacctgtatggatgaaggccagatagcagctgtgtgccgagagtgt ctacaagctttggagtttctacattcaaaccaagtcattcacagggacatcaagagtgac aatattctgctgggaatggatggctctgtcaagttaactgactttggattctgtgcacag ataactccagagcagagcaaaaggagcaccatggtgggaactccatattggatggcacct gaagttgtgacacgcaaggcctatggacccaaggttgacatctggtccctgggcattatg gcaattgaaatgattgagggggagcccccatacctcaatgaaaaccctttgagagccttg tacctcattgctaccaatgggacgccagagcttcagaacccagagaagttgtcagctatt ttccgggacttcctgaaccgctgtcttgagatggatgtggagaagagaggctcagctaaa gagctgctgcagcatcagttcctgaagattgccaagcccctctctagcctgactccactg attgctgcagcaaaagaggcaaccaagaacaatcactga

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