Mus musculus (house mouse): 19165
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Entry
19165 CDS
T01002
Symbol
Psen2, ALG-3, Ad4h, Alg3, PS-2, PS2, Psnl2, STM2
Name
(RefSeq) presenilin 2
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04330
Notch signaling pathway
mmu04722
Neurotrophin signaling pathway
mmu05010
Alzheimer disease
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
19165 (Psen2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
19165 (Psen2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
19165 (Psen2)
05022 Pathways of neurodegeneration - multiple diseases
19165 (Psen2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
19165 (Psen2)
Peptidases and inhibitors [BR:
mmu01002
]
Aspartic peptidases
Family A22: presenilin family
19165 (Psen2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Presenilin
Motif
Other DBs
NCBI-GeneID:
19165
NCBI-ProteinID:
NP_001122077
MGI:
109284
Ensembl:
ENSMUSG00000010609
UniProt:
Q61144
Q3U4P5
LinkDB
All DBs
Position
1:complement(180054569..180091030)
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AA seq
448 aa
AA seq
DB search
MLAFMASDSEEEVCDERTSLMSAESPTSRSCQEGRPGPEDGESTAQWRTQESEEDCEEDP
DRYACSGAPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPLPGYPGEELEEEEERGV
KLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgctcgcattcatggcctctgacagcgaggaagaggtgtgtgatgagcggacgtccttg
atgtcagccgagagccccacatctcgctcctgccaggaaggcaggccaggcccggaggat
ggagagagcactgcccagtggaggactcaggagagcgaagaagactgtgaagaggacccg
gaccgctacgcatgcagtggggctcctgggcgaccgtcgggcctggaggaagagctgacc
ctcaagtatggggcgaagcatgtgatcatgctattcgtgcctgtcacgctgtgtatgatc
gtggtggtggccactatcaagtctgtgcgtttctacactgagaagaacgggcagctcatc
tacacgcccttcacggaggacacgccctcggtgggccagcggctcctcaactccgtgctt
aacaccctcatcatgatcagcgtcatcgtagtcatgaccatcttcctcgtggtactctac
aagtatcgatgctacaagttcatccatggctggctgatcatgtcctccctgatgctcctc
ttcttgttcacctacatctacctcggggaagtgctcaagacctacaatgtggccatggac
tatcccacactcttcctggctgtctggaacttcggggcagtgggcatggtgtgcatccac
tggaaggggcctctggtgctgcagcaggcttaccttattgtgatcagcgcactcatggcc
ctggtgttcatcaagtacctgccggagtggtctgcctgggtcatcttgggtgccatctct
gtgtacgatctcgtggccgtgctgtgccccaaagggccactgaggatgctggtggaaact
gcccaggagagaaatgagcccatatttcctgccctgatatactcatctgccatggtgtgg
acggtgggcatggcaaagctggacccctcctctcaaggagcgctgcagctcccctatgac
ccagagatggaagaagactcctacgacagttttggagaaccctcataccctgaagccttc
gaagcccccctgcctggctacccaggggaggagctggaggaggaggaggaaaggggcgtg
aagctcggcctgggagacttcatcttctacagcgtcctggtgggcaaggctgcagccact
ggcaacggagactggaacactacgctggcctgttttatcgccatcctcattggcttgtgt
ctcaccctcctgctgcttgctgtgttcaagaaggctctgcccgccctccccatctccatc
acctttggactcatcttctacttctccacagacaacctggtgcgccctttcatggacact
ctggcctcccaccagctctacatctga
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