KEGG T01002: 21354

Mus musculus (house mouse): 21354

Entry

21354             CDS       T01002

Symbol

Tap1, ABC17, APT1, Abcb2, Ham-1, Ham1, MTP1, PSF1, RING4, TAP, Tap-1, Y3

Name

(RefSeq) transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

K05653

ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]

Organism

mmu Mus musculus (house mouse)

Pathway

mmu02010

ABC transporters

mmu04145

Phagosome

mmu04612

Antigen processing and presentation

mmu05163

Human cytomegalovirus infection

mmu05168

Herpes simplex virus 1 infection

mmu05169

Epstein-Barr virus infection

mmu05170

Human immunodeficiency virus 1 infection

mmu05340

Primary immunodeficiency

Brite

KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    21354 (Tap1)
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    21354 (Tap1)
09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    21354 (Tap1)
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    21354 (Tap1)
   05168 Herpes simplex virus 1 infection
    21354 (Tap1)
   05163 Human cytomegalovirus infection
    21354 (Tap1)
   05169 Epstein-Barr virus infection
    21354 (Tap1)
  09163 Immune disease
   05340 Primary immunodeficiency
    21354 (Tap1)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    21354 (Tap1)
Enzymes [BR:mmu01000]
7. Translocases
  7.4  Catalysing the translocation of amino acids and peptides
   7.4.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.4.2.14  ABC-type antigen peptide transporter
     21354 (Tap1)
Transporters [BR:mmu02000]
ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB2, 3, 8, 9, 10 subgroups
    21354 (Tap1)

SSDB

Motif

Pfam:

ABC_membrane ABC_tran SMC_N AAA_16 AAA_21 AAA_29 ABC_ATPase AAA_22 AAA_23 AAA_15 AAA_30 AAA_18 AAA_33 SRP54 APS_kinase Zeta_toxin AAA_25

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

MGI:

Ensembl:

UniProt:

LinkDB

Position

17:34406530..34416199

AA seq 724 aa
MAAHVWLAAALLLLVDWLLLRPMLPGIFSLLVPEVPLLRVWVVGLSRWAILGLGVRGVLG
VTAGAHGWLAALQPLVAALSLALPGLALFRELAAWGTLREGDSAGLLYWNSRPDAFAISY
VAALPAAALWHKLGSLWAPSGNRDAGDMLCRMLGFLGPKKRRLYLVLVLLILSCLGEMAI
PFFTGRITDWILQDKTVPSFTRNIWLMSILTIASTALEFASDGIYNITMGHMHGRVHREV
FRAVLRQETGFFLKNPAGSITSRVTEDTANVCESISGTLSLLLWYLGRALCLLVFMFWGS
PYLTLVTLINLPLLFLLPKKLGKVHQSLAVKVQESLAKSTQVALEALSAMPTVRSFANEE
GEAQKFRQKLEEMKTLNKKEALAYVAEVWTTSVSGMLLKVGILYLGGQLVIRGAVSSGNL
VSFVLYQLQFTQAVQVLLSLYPSMQKAVGSSEKIFEYLDRTPCSPLSGSLAPSNMKGLVE
FQDVSFAYPNQPKVQVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLL
DGQCLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGAHDF
ISGFPQGYDTEVGETGNQLSGGQRQAVALARALIRKPLLLILDDATSALDAGNQLRVQRL
LYESPKRASRTVLLITQQLSLAEQAHHILFLREGSVGEQGTHLQLMKRGGCYRAMVEALA
APAD

NT seq 2175 nt +upstreamnt +downstreamnt
atggctgcgcacgtctggctggcggccgccctgctccttctggtggactggctgctgctg
cggcccatgctcccgggaatcttctccctgttggttcccgaggtgccgctgctccgggtc
tgggtggtgggcctgagtcgctgggccatcctaggactaggggtccgcggggtcctcggg
gtcaccgcaggagcccatggctggctggctgctttgcagccgctggtggccgcactgagt
ttggccctgcctggacttgccttgttccgagagctggccgcctggggaacactccgggag
ggtgacagcgctggattactgtactggaacagtcgtccagatgccttcgctatcagttat
gtggcagcattgcccgcagccgccctgtggcacaagttggggagcctctgggcgcccagc
ggcaacagggacgctggagacatgctgtgtcggatgctgggcttcctgggccctaagaag
agacgtctctacctggttctggttctcttgattctctcttgccttggggaaatggccatt
cccttcttcacgggccgcatcactgactggattcttcaggataagacagttcctagcttc
acccgcaacatatggctcatgtccattctcaccatagccagcacagcgctggagtttgca
agtgatggaatctacaacatcaccatgggacacatgcacggccgtgtgcacagagaggtg
tttcgggccgtccttcgccaggagacagggtttttcctgaagaacccagcaggttccatc
acatctcgggtgactgaggacacagccaacgtgtgcgagtccattagtggcacgctgagc
ctgctgctgtggtacctggggcgagccctgtgtctcttggtgttcatgttttgggggtca
ccgtacctcactctggtcaccctgatcaacctgcccctgctttttcttttgcctaagaag
ctgggaaaagtgcatcagtcactggcagtgaaggtgcaggagtctctagcaaagtccacg
caggtggcccttgaggccttatcggcgatgcctactgtgcggagctttgccaacgaggag
ggtgaggcccagaagttcaggcagaagttggaagaaatgaagactctaaacaagaaggag
gccttggcttacgtggctgaagtctggaccacgagtgtctcgggaatgctgctgaaggtg
ggaattctgtacctgggcgggcagctggtgatcagaggggctgtcagcagcggcaacctt
gtctcattcgttctctaccagcttcagttcacccaggctgttcaggtcctgctctccctc
tacccctccatgcagaaggctgtgggctcctcagagaaaatattcgaatacttggaccgg
actccttgctctccactcagtggctcgttggcaccctcaaacatgaaaggccttgtggag
ttccaagatgtctcttttgcctacccaaaccagcccaaagtccaggtgcttcaggggctg
acgttcaccctgcatcctggaacggtgacagcgttggtgggacccaatggatcagggaag
agcaccgtggctgccctgctgcagaacctgtaccagcccaccgggggccagctgctgctg
gatggccagtgcctggtccagtatgatcaccattacctgcacactcaggtggccgcagtg
ggacaagagccgctgctatttggaagaagctttcgagaaaatattgcgtatggcctgaac
cggactccaaccatggaggaaatcacagctgtggccgtggagtctggagcccacgatttc
atctctgggttccctcagggctatgacacagaggtaggtgagactgggaaccagctgtca
ggaggtcagcgacaggcagtggccttggcccgagccttgatccggaagccactcctgctt
atcttggatgatgccaccagtgccctggatgctggcaaccagctacgggtccagcggctc
ctgtatgagagccccaagcgggcttctcggacggttcttcttatcacccagcagctcagc
ctggcagagcaggcccaccacatcctctttctcagagaaggctctgtcggcgagcagggc
acccacctgcagctcatgaagagaggagggtgctaccgggccatggtagaggctcttgcg
gctcctgcagactga

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