KEGG ORTHOLOGY: K05653

ORTHOLOGY: K05653

Entry

K05653                      KO

Symbol

ABCB2, TAP1

Name

ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]

Pathway

map02010

ABC transporters

map04145

Phagosome

map04612

Antigen processing and presentation

map05163

Human cytomegalovirus infection

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05170

Human immunodeficiency virus 1 infection

map05340

Primary immunodeficiency

Disease

H00984

Bare lymphocyte syndrome type1

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05168 Herpes simplex virus 1 infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05163 Human cytomegalovirus infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05169 Epstein-Barr virus infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
  09163 Immune disease
   05340 Primary immunodeficiency
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
Enzymes [BR:ko01000]
7. Translocases
  7.4  Catalysing the translocation of amino acids and peptides
   7.4.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.4.2.14  ABC-type antigen peptide transporter
     K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
Transporters [BR:ko02000]
ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB2, 3, 8, 9, 10 subgroups
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2

Other DBs

GO:

0015433

TC:

3.A.1.209

Genes

HSA:	6890(TAP1)

PTR:	471978(TAP1)

PPS:	100969222(TAP1)

GGO:	101135419(TAP1)

PON:	100444044(TAP1)

NLE:	100605253(TAP1)

HMH:	116460421(TAP1)

MCC:	717726(TAP1)

MCF:	102142346(TAP1)

MTHB:

126952703

MNI:	105474422(TAP1)

CSAB:

103221692(TAP1)

CATY:

105575008(TAP1)

PANU:

101014735(TAP1)

TGE:	112623507(TAP1)

MLEU:

105531118(TAP1)

RRO:	104666626(TAP1)

RBB:	108512976(TAP1)

TFN:	117087011(TAP1)

PTEH:

111528122(TAP1)

CANG:

105513792(TAP1)

CJC:	100407051(TAP1)

SBQ:	101050206(TAP1)

CIMI:

108300077(TAP1)

CSYR:

103271934(TAP1)

MMUR:

105886022(TAP1)

LCAT:

123631801(TAP1)

PCOQ:

105824378(TAP1)

OGA:	100966979(TAP1)

MMU:	21354(Tap1)

MCAL:

110312383(Tap1)

MPAH:

110335738(Tap1)

RNO:	24811(Tap1)

MCOC:

116074432(Tap1)

ANU:	117724686(Tap1)

MUN:	110543126(Tap1)

CGE:	100751458(Tap1)

MAUA:

106022611(Tap1)

PROB:

127224278(Tap1)

PLEU:

114686350(Tap1)

MORG:

121435237(Tap1)

MFOT:

126499463

AAMP:

119823090(Tap1)

NGI:	103748644(Tap1)

HGL:	101711399(Tap1)

CPOC:

100716745(Tap1)

CCAN:

109686707(Tap1)

DORD:

105999856(Tap1)

DSP:	122111481(Tap1)

PLOP:

125353513(Tap1)

NCAR:

124988990

MMMA:

107143776(Tap1)

OCU:

100349155

OPI:	101535942(TAP1)

TUP:	102488648(TAP1)

GVR:	103608009(TAP1)

CFA:	474866(TAP1)

CLUD:

112641381(TAP1)

VVP:	112913865(TAP1)

VLG:	121497333(TAP1)

NPO:	129513013(TAP1)

AML:	100464886(TAP1)

UMR:	103665513(TAP1)

UAH:	113243781(TAP1)

UAR:	123790943(TAP1)

ELK:

111152176

LLV:

125103272

MPUF:

101674199(TAP1)

MNP:	132017858(TAP1)

MLK:	131834271(TAP1)

NVS:	122911173(TAP1)

ORO:	101370146(TAP1)

EJU:	114222136(TAP1)

ZCA:	113926807(TAP1)

MLX:	118001395(TAP1)

NSU:	110575563(TAP1)

LWW:	102749278(TAP1)

FCA:	101083591(TAP1)

PYU:	121029258(TAP1)

PCOO:

112862344(TAP1)

PBG:	122489371(TAP1)

PVIV:

125165407(TAP1)

LRUF:

124528921

PTG:	102969103(TAP1)

PPAD:

109271409(TAP1)

PUC:

125938390

AJU:

106976125

HHV:	120238159(TAP1)

BTA:	524959(TAP1)

BOM:	102269065(TAP1)

BIU:	109577139(TAP1)

BBUB:

102391940(TAP1)

BBIS:

104994883(TAP1)

CHX:	102181173(TAP1)

OAS:	101115580(TAP1)

BTAX:

128056161(TAP1)

ODA:	120869861(TAP1)

CCAD:

122429562(TAP1)

MBEZ:

129543429(TAP1)

SSC:	733649(TAP1)

CFR:	102506212(TAP1)

CBAI:

105064241(TAP1)

CDK:	105101403(TAP1)

VPC:	102535891(TAP1)

BACU:

103011180(TAP1)

BMUS:

118904086(TAP1)

LVE:	103084615(TAP1)

OOR:	101289708(TAP1)

DLE:	111178660(TAP1)

PCAD:

102995173(TAP1)

PSIU:

116762103(TAP1)

NASI:

112413857(TAP1)

ECB:	100060845(TAP1)

EAI:	106834612(TAP1)

MYB:	102252020(TAP1)

MYD:	102761514(TAP1)

MMYO:

118679553(TAP1)

MLF:	102421555(TAP1)

PKL:	118705649(TAP1)

EFUS:

129150467(TAP1)

MNA:	107542669(TAP1)

DRO:	112302332(TAP1)

SHON:

118991465(TAP1)

AJM:	119049933(TAP1)

PDIC:

114494744(TAP1)

PHAS:

123816513(TAP1)

MMF:	118621195(TAP1)

PPAM:

129067354(TAP1)

HAI:	109378146(TAP1)

RFQ:	117020460(TAP1)

PALE:

102893312(TAP1)

PGIG:

120597635(TAP1)

PVP:	105300966(TAP1)

RAY:	107511995(TAP1)

MJV:	108388306 108405341(TAP1)

TOD:	119252321(TAP1)

SARA:

101544289(TAP1)

LAV:	100672952(TAP1)

TMU:

101341807

ETF:	101639668(TAP1)

DNM:	101433457(TAP1)

MDO:	100026750(TAP1)

GAS:	123245211(TAP1)

SHR:	116423203(TAP1)

AFZ:

127561620

PCW:	110199321 110199346(TAP1) 110199416

OAA:	100088116(TAP1)

GGA:	427727(TAP1)

PCOC:

116236743(TAP1)

MGP:	100545399 104913621

CJO:	107321559(TAP1)

TPAI:

128074266(TAP1)

LMUT:

125686236(TAP1)

NMEL:

110406673(TAP1)

APLA:

101797680 119718657

ACYG:

106029502(TAP1)

CATA:

118260283(TAP1)

AFUL:

116500214(TAP1)

LSR:

PMOA:

PRUF:

FAB:

OMA:

PHI:

PMAJ:

CCW:

CBRC:

ETL:

HRT:

EGZ:

ACUN:

TALA:

116963340(TAP1)

AFOR:

103908011

ACHC:

115338299(TAP1)

HLE:	104834904(TAP1)

AGEN:

126034916

SHAB:

115603459(TAP1)

CPEA:

104394208(TAP1)

RTD:

128901640

BRHI:

104498062

AAM:	106492644(TAP1)

CMY:	119567530(TAP1)

CPIC:

101952783

CABI:

116821656(TAP1) 116825565

MRV:	120394809 120394816(TAP1)

ACS:	100554917 100558440 100558977 103282465

ASAO:

132765336 132765811 132769673

PVT:	110071192(TAP1)

SUND:

121922961 121923358

PBI:	103063236(TAP1)

PMUR:

107296739(TAP1)

CTIG:

120317827(TAP1)

TSR:

106544595

PGUT:

117670039(TAP1)

APRI:

131191900(TAP1)

PTEX:

113451019(TAP1)

NSS:	113425983(TAP1)

VKO:	123023274(TAP1)

PMUA:

114592172 114592235(TAP1)

PRAF:

128409344(TAP1)

ZVI:	118080216(TAP1)

STOW:

125428884(TAP1)

XLA:	100329838(tap1.L)

XTR:	100494735(tap1) 108648266

NPR:	108788360(TAP1)

RTEM:

120914285(TAP1)

BBUF:

120977441(TAP1)

BGAR:

122919679(TAP1)

MUO:	115459444 115466179

GSH:	117349879(TAP1)

DRE:	100333043(tap1)

SRX:	107711531(tap1) 107715579

SANH:

107671442 107688213

SGH:	107592117 107592491(tap1)

CCAR:

109056322(tap1)

CAUA:

113059348 113101282 113115685

CGIB:

127975187 128029986

PTET:

122333975(tap1)

LROH:

127178906(tap1)

OMC:	131521848(tap1)

PPRM:

120491127(tap1)

RKG:	130078823(tap1)

MAMB:

125243603(tap1)

CIDE:

127496810

MASI:

127453367 127454128

TROS:

130557752(tap1)

TDW:	130433405(tap1)

MANU:

129448764(tap1)

IPU:

108256340

IFU:	128600046(tap1)

PHYP:

113532964

SMEO:

124375525(tap1)

TFD:	113649843(tap1)

TVC:	132840123(tap1)

AMEX:

103042617(tap1)

CMAO:

118798907(tap1)

EEE:	113578824(tap1)

CHAR:

105891881(tap1)

TRU:

101077331

TFS:	130532512(tap1)

TNG:	GSTEN00002627G001

LCO:

104928642

NCC:

104965249

TBEN:

117500552(tap1)

CGOB:

115021787

PGEO:

117460585(tap1)

GACU:

117543224(tap1)

EMAC:

134861502(tap1)

ELY:	117265256(tap1)

EFO:	125893418(tap1)

PLEP:

121945983(tap1)

SLUC:

116036106(tap1)

ECRA:

117945671(tap1)

ESP:

116690885

PFLV:

114557798

GAT:	120810165(tap1)

PPUG:

119197942(tap1)

AFB:	129109229(tap1)

CLUM:

117728065(tap1)

PSWI:

130212911(tap1)

MSAM:

119897095(tap1)

SCHU:

122881501(tap1)

CUD:	121513613(tap1)

ALAT:

119005680(tap1)

MZE:	101484302(tap1)

ONL:	100701175(tap1)

OAU:	116311333(tap1)

OLA:	101162709(tap1)

OML:	112136733(tap1)

CSAI:

133439275(tap1)

XMA:	102217160(tap1)

XCO:	114141733(tap1)

XHE:	116717209(tap1)

PRET:

103477852(tap1)

PFOR:

103146690(tap1)

PLAI:

106948877

PMEI:

106903295(tap1)

GAF:	122831242(tap1)

PPRL:

129370786(tap1)

CVG:

107082986

CTUL:

119777431(tap1)

GMU:	124866324(tap1)

NFU:

107379160

KMR:	108245991(tap1)

ALIM:

106523077(tap1)

NWH:	119409807(tap1)

AOCE:

111577918

MCEP:

125016940(tap1)

CSEM:

103388956

POV:

109647062

SSEN:

122774097(tap1)

HHIP:

117776256(tap1)

HSP:	118114170(tap1)

SMAU:

118284721(tap1)

LCF:

108899590

SDU:	111222621(tap1)

SLAL:

111655648(tap1)

XGL:	120784568(tap1)

HCQ:	109521010(tap1)

SSCV:

125974814

SBIA:

133501431(tap1)

PEE:	133401619(tap1)

PTAO:

133479890(tap1)

BPEC:

110171064

MALB:

109965574(tap1)

BSPL:

114843532(tap1)

SJO:	128366653(tap1)

SASA:

100136585(tap1)

STRU:

115178246(tap1)

OTW:

112222999

OMY:	110487866(tap1)

OGO:	123997694(tap1)

ONE:	115114169 115141115(tap1)

OKI:	109902065 109903718

OKE:	118364394(tap1)

SALP:

111959198 111965141

SNH:	120031373 120048383

CCLU:

121559689 123484627

ELS:

105021865

SFM:	108926769 114909099

PKI:

111838464

AANG:

118225073(tap1)

PSPA:

121298813 121304295(tap1)

ARUT:

117433949 117962717

PSEX:

120539144(tap1)

LCM:	102361710(TAP1)

CMK:

103173390

HOC:	132832854(tap1)

LERI:

129694074 129694463

» show all

Reference

PMID:23340176

Authors

Xu M, Li L, Liu Z, Jiao Z, Xu P, Kong X, Huang H, Zhang Y

Title

ABCB2 (TAP1) as the downstream target of SHH signaling enhances pancreatic ductal adenocarcinoma drug resistance.

Journal

Cancer Lett 333:152-8 (2013)
DOI:10.1016/j.canlet.2013.01.002

Sequence

[hsa:6890]

Reference

PMID:2259383

Authors

Trowsdale J, Hanson I, Mockridge I, Beck S, Townsend A, Kelly A

Title

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters.

Journal

Nature 348:741-4 (1990)
DOI:10.1038/348741a0

Sequence

[hsa:6890]

LinkDB

DBGET integrated database retrieval system