KEGG   Mus musculus (house mouse): 216233
Entry
216233            CDS       T01002                                 
Symbol
Socs2, 8030460M17, CIS2, Cish2, D130043N08Rik, JAB, SOCS-2, SSI-2, hg
Name
(RefSeq) suppressor of cytokine signaling 2
  KO
K04695  suppressor of cytokine signaling 2
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04630  JAK-STAT signaling pathway
mmu04910  Insulin signaling pathway
mmu04917  Prolactin signaling pathway
mmu04930  Type II diabetes mellitus
mmu04935  Growth hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    216233 (Socs2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    216233 (Socs2)
   04917 Prolactin signaling pathway
    216233 (Socs2)
   04935 Growth hormone synthesis, secretion and action
    216233 (Socs2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    216233 (Socs2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mmu04121]
    216233 (Socs2)
Ubiquitin system [BR:mmu04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     216233 (Socs2)
SSDB
Motif
Pfam: SH2 SOCS_box SH2_2 DUF7063 DUF6987 Condensation
Other DBs
NCBI-GeneID: 216233
NCBI-ProteinID: NP_001162126
MGI: 1201787
Ensembl: ENSMUSG00000020027
UniProt: O35717 Q548Q7
LinkDB
Position
10:complement(95219765..95253176)
AA seq 198 aa
MTLRCLEPSGNGADRTRSQWGTAGLPEEQSPEAARLAKALRELSQTGWYWGSMTVNEAKE
KLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFD
SVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLAINKCTGTIWG
LPLPTRLKDYLEEYKFQV
NT seq 597 nt   +upstreamnt  +downstreamnt
atgaccctgcggtgcctggagccctccgggaatggagcggacaggacgcggagccagtgg
gggaccgcggggttgccggaggaacagtcccccgaggcggcgcgtctggcgaaagccctg
cgcgagctcagtcaaacaggatggtactggggaagtatgactgttaatgaagccaaagag
aaattaaaagaggctccagaaggaactttcttgattagagatagttcgcattcagactac
ctactaactatatccgttaagacgtcagctggaccgactaacctgcggattgagtaccaa
gatgggaaattcagattggattctatcatatgtgtcaagtccaagcttaaacagtttgac
agtgtggttcatctgattgactactatgtccagatgtgcaaggataaacggacaggccca
gaagccccacggaatgggactgttcacctgtacctgaccaaacctctgtatacatcagca
cccactctgcagcatttctgtcgactcgccattaacaaatgtaccggtacgatctgggga
ctgcctttaccaacaagactaaaagattacttggaagaatataaattccaggtataa

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