Mus musculus (house mouse): 21926
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Entry
21926 CDS
T01002
Symbol
Tnf, DIF, TNF-a, TNF-alpha, TNFSF2, TNFalpha, Tnfa, Tnfsf1a, Tnlg1f
Name
(RefSeq) tumor necrosis factor
KO
K03156
tumor necrosis factor superfamily, member 2
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01523
Antifolate resistance
mmu04010
MAPK signaling pathway
mmu04060
Cytokine-cytokine receptor interaction
mmu04061
Viral protein interaction with cytokine and cytokine receptor
mmu04064
NF-kappa B signaling pathway
mmu04071
Sphingolipid signaling pathway
mmu04150
mTOR signaling pathway
mmu04210
Apoptosis
mmu04217
Necroptosis
mmu04350
TGF-beta signaling pathway
mmu04380
Osteoclast differentiation
mmu04612
Antigen processing and presentation
mmu04620
Toll-like receptor signaling pathway
mmu04621
NOD-like receptor signaling pathway
mmu04622
RIG-I-like receptor signaling pathway
mmu04625
C-type lectin receptor signaling pathway
mmu04640
Hematopoietic cell lineage
mmu04650
Natural killer cell mediated cytotoxicity
mmu04657
IL-17 signaling pathway
mmu04660
T cell receptor signaling pathway
mmu04664
Fc epsilon RI signaling pathway
mmu04668
TNF signaling pathway
mmu04920
Adipocytokine signaling pathway
mmu04930
Type II diabetes mellitus
mmu04931
Insulin resistance
mmu04932
Non-alcoholic fatty liver disease
mmu04933
AGE-RAGE signaling pathway in diabetic complications
mmu04936
Alcoholic liver disease
mmu04940
Type I diabetes mellitus
mmu05010
Alzheimer disease
mmu05014
Amyotrophic lateral sclerosis
mmu05020
Prion disease
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05132
Salmonella infection
mmu05133
Pertussis
mmu05134
Legionellosis
mmu05135
Yersinia infection
mmu05140
Leishmaniasis
mmu05142
Chagas disease
mmu05143
African trypanosomiasis
mmu05144
Malaria
mmu05145
Toxoplasmosis
mmu05146
Amoebiasis
mmu05152
Tuberculosis
mmu05160
Hepatitis C
mmu05161
Hepatitis B
mmu05163
Human cytomegalovirus infection
mmu05164
Influenza A
mmu05165
Human papillomavirus infection
mmu05166
Human T-cell leukemia virus 1 infection
mmu05168
Herpes simplex virus 1 infection
mmu05169
Epstein-Barr virus infection
mmu05170
Human immunodeficiency virus 1 infection
mmu05171
Coronavirus disease - COVID-19
mmu05205
Proteoglycans in cancer
mmu05310
Asthma
mmu05321
Inflammatory bowel disease
mmu05322
Systemic lupus erythematosus
mmu05323
Rheumatoid arthritis
mmu05330
Allograft rejection
mmu05332
Graft-versus-host disease
mmu05410
Hypertrophic cardiomyopathy
mmu05414
Dilated cardiomyopathy
mmu05417
Lipid and atherosclerosis
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
21926 (Tnf)
04350 TGF-beta signaling pathway
21926 (Tnf)
04064 NF-kappa B signaling pathway
21926 (Tnf)
04668 TNF signaling pathway
21926 (Tnf)
04071 Sphingolipid signaling pathway
21926 (Tnf)
04150 mTOR signaling pathway
21926 (Tnf)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
21926 (Tnf)
04061 Viral protein interaction with cytokine and cytokine receptor
21926 (Tnf)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
21926 (Tnf)
04217 Necroptosis
21926 (Tnf)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
21926 (Tnf)
04620 Toll-like receptor signaling pathway
21926 (Tnf)
04621 NOD-like receptor signaling pathway
21926 (Tnf)
04622 RIG-I-like receptor signaling pathway
21926 (Tnf)
04625 C-type lectin receptor signaling pathway
21926 (Tnf)
04650 Natural killer cell mediated cytotoxicity
21926 (Tnf)
04612 Antigen processing and presentation
21926 (Tnf)
04660 T cell receptor signaling pathway
21926 (Tnf)
04657 IL-17 signaling pathway
21926 (Tnf)
04664 Fc epsilon RI signaling pathway
21926 (Tnf)
09152 Endocrine system
04920 Adipocytokine signaling pathway
21926 (Tnf)
09158 Development and regeneration
04380 Osteoclast differentiation
21926 (Tnf)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
21926 (Tnf)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
21926 (Tnf)
05170 Human immunodeficiency virus 1 infection
21926 (Tnf)
05161 Hepatitis B
21926 (Tnf)
05160 Hepatitis C
21926 (Tnf)
05171 Coronavirus disease - COVID-19
21926 (Tnf)
05164 Influenza A
21926 (Tnf)
05168 Herpes simplex virus 1 infection
21926 (Tnf)
05163 Human cytomegalovirus infection
21926 (Tnf)
05169 Epstein-Barr virus infection
21926 (Tnf)
05165 Human papillomavirus infection
21926 (Tnf)
09171 Infectious disease: bacterial
05132 Salmonella infection
21926 (Tnf)
05135 Yersinia infection
21926 (Tnf)
05133 Pertussis
21926 (Tnf)
05134 Legionellosis
21926 (Tnf)
05152 Tuberculosis
21926 (Tnf)
09174 Infectious disease: parasitic
05146 Amoebiasis
21926 (Tnf)
05144 Malaria
21926 (Tnf)
05145 Toxoplasmosis
21926 (Tnf)
05140 Leishmaniasis
21926 (Tnf)
05142 Chagas disease
21926 (Tnf)
05143 African trypanosomiasis
21926 (Tnf)
09163 Immune disease
05310 Asthma
21926 (Tnf)
05322 Systemic lupus erythematosus
21926 (Tnf)
05323 Rheumatoid arthritis
21926 (Tnf)
05321 Inflammatory bowel disease
21926 (Tnf)
05330 Allograft rejection
21926 (Tnf)
05332 Graft-versus-host disease
21926 (Tnf)
09164 Neurodegenerative disease
05010 Alzheimer disease
21926 (Tnf)
05014 Amyotrophic lateral sclerosis
21926 (Tnf)
05020 Prion disease
21926 (Tnf)
05022 Pathways of neurodegeneration - multiple diseases
21926 (Tnf)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
21926 (Tnf)
05418 Fluid shear stress and atherosclerosis
21926 (Tnf)
05410 Hypertrophic cardiomyopathy
21926 (Tnf)
05414 Dilated cardiomyopathy
21926 (Tnf)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
21926 (Tnf)
04940 Type I diabetes mellitus
21926 (Tnf)
04936 Alcoholic liver disease
21926 (Tnf)
04932 Non-alcoholic fatty liver disease
21926 (Tnf)
04931 Insulin resistance
21926 (Tnf)
04933 AGE-RAGE signaling pathway in diabetic complications
21926 (Tnf)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
21926 (Tnf)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
mmu04052
]
21926 (Tnf)
00536 Glycosaminoglycan binding proteins [BR:
mmu00536
]
21926 (Tnf)
Cytokines and neuropeptides [BR:
mmu04052
]
Cytokines
Tumor necrosis fators
21926 (Tnf)
Glycosaminoglycan binding proteins [BR:
mmu00536
]
Heparan sulfate / Heparin
Cytokines
21926 (Tnf)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TNF
DUF956
Motif
Other DBs
NCBI-GeneID:
21926
NCBI-ProteinID:
NP_038721
MGI:
104798
Ensembl:
ENSMUSG00000024401
UniProt:
P06804
Q3U593
Structure
PDB
LinkDB
All DBs
Position
17:complement(35418343..35420983)
Genome browser
AA seq
235 aa
AA seq
DB search
MSTESMIRDVELAEEALPQKMGGFQNSRRCLCLSLFSFLLVAGATTLFCLLNFGVIGPQR
DEKFPNGLPLISSMAQTLTLRSSSQNSSDKPVAHVVANHQVEEQLEWLSQRANALLANGM
DLKDNQLVVPADGLYLVYSQVLFKGQGCPDYVLLTHTVSRFAISYQEKVNLLSAVKSPCP
KDTPEGAELKPWYEPIYLGGVFQLEKGDQLSAEVNLPKYLDFAESGQVYFGVIAL
NT seq
708 nt
NT seq
+upstream
nt +downstream
nt
atgagcacagaaagcatgatccgcgacgtggaactggcagaagaggcactcccccaaaag
atggggggcttccagaactccaggcggtgcctatgtctcagcctcttctcattcctgctt
gtggcaggggccaccacgctcttctgtctactgaacttcggggtgatcggtccccaaagg
gatgagaagttcccaaatggcctccctctcatcagttctatggcccagaccctcacactc
agatcatcttctcaaaattcgagtgacaagcctgtagcccacgtcgtagcaaaccaccaa
gtggaggagcagctggagtggctgagccagcgcgccaacgccctcctggccaacggcatg
gatctcaaagacaaccaactagtggtgccagccgatgggttgtaccttgtctactcccag
gttctcttcaagggacaaggctgccccgactacgtgctcctcacccacaccgtcagccga
tttgctatctcataccaggagaaagtcaacctcctctctgccgtcaagagcccctgcccc
aaggacacccctgagggggctgagctcaaaccctggtatgagcccatatacctgggagga
gtcttccagctggagaagggggaccaactcagcgctgaggtcaatctgcccaagtactta
gactttgcggagtccgggcaggtctactttggagtcattgctctgtga
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