Mus musculus (house mouse): 22030 Help Entry 22030             CDS       T01002                                  Symbol Traf2 Name (RefSeq) TNF receptor-associated factor 2   KO K03173   TNF receptor-associated factor 2 [EC:2.3.2.27] Organism mmu  Mus musculus (house mouse) Pathway mmu04010   MAPK signaling pathway mmu04064   NF-kappa B signaling pathway mmu04071   Sphingolipid signaling pathway mmu04137   Mitophagy - animal mmu04141   Protein processing in endoplasmic reticulum mmu04210   Apoptosis mmu04217   Necroptosis mmu04380   Osteoclast differentiation mmu04621   NOD-like receptor signaling pathway mmu04622   RIG-I-like receptor signaling pathway mmu04657   IL-17 signaling pathway mmu04668   TNF signaling pathway mmu04920   Adipocytokine signaling pathway mmu04932   Non-alcoholic fatty liver disease mmu05010   Alzheimer disease mmu05014   Amyotrophic lateral sclerosis mmu05016   Huntington disease mmu05017   Spinocerebellar ataxia mmu05022   Pathways of neurodegeneration - multiple diseases mmu05132   Salmonella infection mmu05135   Yersinia infection mmu05160   Hepatitis C mmu05163   Human cytomegalovirus infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05200   Pathways in cancer mmu05203   Viral carcinogenesis mmu05222   Small cell lung cancer mmu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     22030 (Traf2)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     22030 (Traf2)    04064 NF-kappa B signaling pathway     22030 (Traf2)    04668 TNF signaling pathway     22030 (Traf2)    04071 Sphingolipid signaling pathway     22030 (Traf2)  09140 Cellular Processes   09141 Transport and catabolism    04137 Mitophagy - animal     22030 (Traf2)   09143 Cell growth and death    04210 Apoptosis     22030 (Traf2)    04217 Necroptosis     22030 (Traf2)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     22030 (Traf2)    04622 RIG-I-like receptor signaling pathway     22030 (Traf2)    04657 IL-17 signaling pathway     22030 (Traf2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     22030 (Traf2)   09158 Development and regeneration    04380 Osteoclast differentiation     22030 (Traf2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     22030 (Traf2)    05203 Viral carcinogenesis     22030 (Traf2)   09162 Cancer: specific types    05222 Small cell lung cancer     22030 (Traf2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     22030 (Traf2)    05160 Hepatitis C     22030 (Traf2)    05168 Herpes simplex virus 1 infection     22030 (Traf2)    05163 Human cytomegalovirus infection     22030 (Traf2)    05167 Kaposi sarcoma-associated herpesvirus infection     22030 (Traf2)    05169 Epstein-Barr virus infection     22030 (Traf2)   09171 Infectious disease: bacterial    05132 Salmonella infection     22030 (Traf2)    05135 Yersinia infection     22030 (Traf2)   09164 Neurodegenerative disease    05010 Alzheimer disease     22030 (Traf2)    05014 Amyotrophic lateral sclerosis     22030 (Traf2)    05016 Huntington disease     22030 (Traf2)    05017 Spinocerebellar ataxia     22030 (Traf2)    05022 Pathways of neurodegeneration - multiple diseases     22030 (Traf2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     22030 (Traf2)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     22030 (Traf2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:mmu03019]     22030 (Traf2)    04121 Ubiquitin system [BR:mmu04121]     22030 (Traf2) Enzymes [BR:mmu01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      22030 (Traf2) Messenger RNA biogenesis [BR:mmu03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Stress granule specific factors      22030 (Traf2) Ubiquitin system [BR:mmu04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     22030 (Traf2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TRAF-mep_MATH MATH_2 TRAF_BIRC3_bd zf-TRAF TRAF2_zf zf-C3HC4 TRAF3_RING zf-RING_6 zf-C3HC4_2 PIN_9 MATH Cep57_CLD DUF4795 Motif Other DBs NCBI-GeneID:  22030 NCBI-ProteinID:  NP_033448 MGI:  101835 Ensembl:  ENSMUSG00000026942 UniProt:  P39429 Q3U8L1 Q8C6X9 LinkDB All DBs Position 2:complement(25407994..25436952) Genome browser AA seq 501 aa AA seqDB search MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTS ILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKE YESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYE VCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRL REHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTA EACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISD FTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDA LLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEA KNSYVRDDAIFIKAIVDLTGL NT seq 1506 nt NT seq  +upstreamnt  +downstreamnt atggctgcagccagtgtgacttcccctggctccctagaactgctacagcctggcttctcc aagaccctcctggggaccaggttagaagccaagtacctctgttcagcctgcaaaaacatc ctgcggaggcctttccaggcccagtgtgggcaccgctactgctccttctgcctgaccagc atcctcagctctgggccccagaactgtgctgcctgtgtctatgaaggcctgtatgaagaa ggcatttctattttagagagtagttcggcctttccagataacgctgcccgcagagaggtg gagagcctgccagctgtctgtcccaatgatggatgcacttggaaggggaccttgaaagaa tacgagagctgccacgaaggactttgcccattcctgctgacggagtgtcctgcatgtaaa ggcctggtccgcctcagcgagaaggagcaccacactgagcaggaatgccccaaaaggagc ctgagctgccagcactgcagagcaccctgtagccacgtggacctggaggtacactatgag gtctgccccaagtttcccttaacctgtgatggctgtggcaagaagaagatccctcgggag acgtttcaggaccatgttagagcatgcagcaaatgccgggttctctgcagattccacacc gttggctgttcagagatggtggagactgagaacctgcaggatcatgagctgcagcggcta cgggaacacctagccctactgctgagctcattcttggaggcccaagcctctccaggaacc ttgaaccaggtggggccagagctactccagcggtgccagattttggagcagaagatagca acctttgagaacattgtctgcgtcttgaaccgtgaagtagagagggtagcagtgactgca gaggcttgtagccggcagcaccggctagaccaggacaagattgaggccctgagtaacaag gtgcaacagctggagaggagcatcggcctcaaggacctggccatggctgacctggagcag aaggtctccgagttggaagtatccacctatgatggggtcttcatctggaagatctctgac ttcaccagaaagcgtcaggaagccgtagctggccggacaccagctatcttctccccagcc ttctacacaagcagatatggctacaagatgtgtctacgagtctacttgaatggcgacggc actgggcggggaactcatctgtctctcttcttcgtggtgatgaaaggccccaatgatgct ctgttgcagtggccttttaatcagaaggtaacattgatgttgctggaccataacaaccgg gagcatgtgatcgacgcattcaggcccgatgtaacctcgtcctccttccagaggcctgtc agtgacatgaacatcgccagtggctgccccctcttctgccctgtgtccaagatggaggcc aagaattcctatgtgcgggatgatgcgatcttcatcaaagctattgtggacctaacagga ctctag

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