Mus musculus (house mouse): 330662
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Entry
330662 CDS
T01002
Symbol
Dock1, 9130006G06Rik, D630004B07Rik, b2b3190Clo
Name
(RefSeq) dedicator of cytokinesis 1
KO
K13708
dedicator of cytokinesis protein 1
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04148
Efferocytosis
mmu04510
Focal adhesion
mmu04666
Fc gamma R-mediated phagocytosis
mmu04810
Regulation of actin cytoskeleton
mmu05100
Bacterial invasion of epithelial cells
mmu05135
Yersinia infection
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
330662 (Dock1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
330662 (Dock1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
330662 (Dock1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
330662 (Dock1)
09160 Human Diseases
09171 Infectious disease: bacterial
05135 Yersinia infection
330662 (Dock1)
05100 Bacterial invasion of epithelial cells
330662 (Dock1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
330662 (Dock1)
Membrane trafficking [BR:
mmu04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
330662 (Dock1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOCK_N
DOCK-C2
DHR-2_Lobe_C
DHR-2_Lobe_A
DHR-2_Lobe_B
SH3_1
SH3_9
SH3_2
Motif
Other DBs
NCBI-GeneID:
330662
NCBI-ProteinID:
NP_001028592
MGI:
2429765
Ensembl:
ENSMUSG00000058325
UniProt:
Q8BUR4
Structure
PDB
LinkDB
All DBs
Position
7:134272416..134775376
Genome browser
AA seq
1865 aa
AA seq
DB search
MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF
PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH
MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS
TISLFRAHEVASKQVEERLQEEKSQKQNMDINRQAKFAATPSLALFVNLKNVVCKIGEDA
EVLMSLYDPMESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ
IVRVGRMELRDSNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQAVAGENDF
LQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIM
PGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKS
VIYYQVKQPRWFETLKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYD
GTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKGELEEKGHSATGKGMQSLGSCTISKD
SFQISTLVCSTKLTQNVDLLGLLKWRSNTNLLQQNLRQLMKVDGGEVVKFLQDTLDALFN
IMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLR
TYVASAEKPGVNEQLYKAIKALEYIFKFIVRSRVLFNQLYENKGEADFVESLLQLFRSIN
DMMSSLSELTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPAGLLTVQKLSC
LIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEELEACCQLLSNILEVLYRKDVGPTQ
RHVQIIMETLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTD
VVDFLMETFIMFKNLIGKNVYPFDWVIMNTMQNKVFLRAINQYADMLNKRFLDQANFELQ
LWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKF
IPEMVGPILEMTLIPETELRKATLPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGR
GDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKDNRMSCT
VNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCAAHLTQ
RDGFQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYETEMFDYEQLSELLKK
QAQFYENIVKVIRPKPDYFAVGYYGQGFPSFLRGKVFIYRGKEYERREDFEARLLTQFPN
AEKMKTTSPPGDDIKTSPGQYIQCFTVKPKLDLPPRFHRPVSEQIVSFYRVNEVQRFEYS
RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT
NDKISSMVQQHLDDPGLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHGQ
IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGVRTMPSG
LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSFSSDSTPSRPGSDGFALEPLLPKKMHSR
SQDKLDKDDPDKEKKDKKKEKRNSKHQEIFDKEFKPADSSLQQSEAVILSETISPLRPQR
PKSQVINVIGNERRFSVSPASPSSQQTPPPVTPRAKLSFSIQPSLELNGMMGMDVADVPP
PLPLKGNMADYGNLMENQDMMVSPTSPPPPPPQRQQPPPLPSKTPPPPPPKTTRKQTSVD
SGIVQ
NT seq
5598 nt
NT seq
+upstream
nt +downstream
nt
atgacgcgctgggtccccaccaagcgagaggagaagtacggcgtggccttttacaactac
gatgccaggggagcagatgaactgtcccttcaaattggagacaccgtgcacatcctagaa
acttatgaagggtggtacagaggctacaccttaaggaaaaagtctaaaaagggtatattt
cctgcttcatatattcatcttaaagaagccattgttgaaggaaaagggcaacatgaaacc
gtcatccctggggacctcccccttatacaggaagtcaccacaacgcttcgagagtggtct
accatctggaggcaactttatgtgcaagataatagagagatgtttcgaagtgtgcgacac
atgatctatgaccttattgaatggcggtcgcagatcctttctggaactctgccccaggat
gagctcaaagagctgaagaagaaggtcacagccaaaattgattatggaaacagaattctt
gatttggacctggtggtgagggatgaagatgggaacattttggacccggaactaactagc
accatcagtctcttccgagcacacgaagttgcttctaaacaagtggaggagagactgcaa
gaggagaaatctcaaaagcagaacatggatatcaacagacaagccaagtttgcagccacc
ccatcgctggccttgtttgttaacctcaaaaatgtggtttgtaaaataggagaagatgct
gaagttctcatgtctctttatgaccccatggagtccaaattcatcagtgagaactatctg
gtccgctggtcaagttcaggattaccaaaagatattgatcggttacataacttgcgagct
gtgtttacggatctggggagcaaagacttgaaaagggagaaaattagtttcgtctgccag
attgtccgtgtcggtcgcatggagctgagggacagcaacacgaggaagctgacttcgggg
ctgcggcgacctttcggcgtggctgtgatggatgtgacagacataataaacgggaaagtc
gatgatgaagataaacagcatttcatccccttccaggcggtggcaggggagaatgacttc
cttcaaactgtcataaacaaagtcattgcagccaaagaagtcaaccacaagggacaaggt
ttgtgggtaaccttgaaattacttcctggagacatccatcagattcggaaggagtttcct
cacttggtggacaggaccacagctgtggcccgcaagacagggtttcctgagattattatg
ccaggtgatgttcgaaatgatatctatgtgacattagttcaaggggattttgataaaggc
agtaaaacaactgcgaagaacgtggaggtgacagtgtctgtctatgatgaagatgggaag
cgattggagcacgtgattttccccggtgctggcgacgaggcgatctccgagtacaaatcg
gtgatttattatcaagtgaagcagcctcgctggtttgagacccttaaggtggccatcccc
attgaggacgtgaaccggagtcaccttcgattcaccttccgccatagatcctcgcaggac
tccaaggataaatctgaaaagatcttcgcactggcctttgtgaagctgatgagatacgat
gggaccaccctgagagacggggagcatgaccttattgtctacaaggctgaagccaaaaag
ctcgaagatgcagccacatacttgagcctccctagtaccaagggggagttggaagaaaag
ggccactcagccacaggcaaaggaatgcagagtcttgggagttgtaccatcagcaaagac
tctttccagatctccactctggtgtgttccacgaaactgacccagaacgtggacctcctg
gggctgttgaagtggagatccaacaccaaccttctgcagcagaacttgaggcagttgatg
aaggtggacggtggtgaagtggtgaagttccttcaggacaccttggatgccctcttcaac
atcatgatggagaactcagagagtgagacgtttgataccttggtgtttgatgctctggtc
tttattattggactaatcgcggataggaaatttcagcattttaatcctgttttggagact
tacattaagaaacacttcagtgcaacattagcctacacgaagctgaccaaggtgttacgg
acctacgtggccagcgcagagaagccgggagtcaacgagcagctgtacaaagccataaaa
gccttggagtacatcttcaagttcatagtgcgctcacgggtactgttcaaccagctgtat
gaaaacaagggggaagctgacttcgtggagtccttgttgcagctgttccggtccatcaac
gacatgatgagcagcctgtcagagctcacagtcagggtgaagggggcagccctgaagtac
ttgccgacgatcgtcaatgatgtgaagttggtgtttgatcccaaggagctcagcaaaatg
ttcacggaattcatcctgaatgtccctgcgggcttgctgacggtccagaagctctcctgc
ctgattgagattgttcacagtgacctcttcacacagcatgactgcagagagatcctgctc
cccatgatgacagaccagctcaagtaccacctggagaggcaggaggagctggaggcttgt
tgccagctgcttagcaacatcctggaggtgctataccggaaggatgtgggaccgactcag
aggcacgtccagatcatcatggagacgctgcttaggactgtgaacaggacggtcatttcc
atggggcgggactccgagctcattgggaactttgtggcttgcatgacagccattttacgg
cagatggaagactaccattatgcacacctgatcaagacctttgggaaaatgaggacagat
gtcgtggattttctgatggagacattcatcatgtttaagaacctcatcgggaagaacgtc
taccccttcgactgggtgataatgaacacgatgcagaacaaagtctttctgcgggcgatt
aatcagtatgcagatatgctgaacaagagatttctggatcaagccaactttgagctgcag
ctgtggaacaactactttcacctggccgtggctttcctcactcaagagtccctgcaactg
gagaatttttcaagtgctaagagagctaaaatccttaacaagtatggagacatgaggagg
cagattggctttgagatcagagacatgtggtacaacctgggtcaacacaagataaaattc
atcccagaaatggttggcccaatattggaaatgacattgattcctgagacagagcttcga
aaagccacccttcccatcttcttcgacatgatgcagtgtgaattccactccacccggagc
tttcaaatgtttgaaaatgagatcatcactaagctggatcatgaagtggaaggaggcaga
ggagacgagcaatacaaagtgttatttgataaaatcctcctggagcactgcaggaagcat
aaatacctcgccaagacaggagaaacttttgtgaagctcgtagtgcggttgatggagagg
ctcctggactacaggaccatcatgcatgacgaaaacaaagacaatcggatgagctgcacc
gtcaacgtgctgaatttctacaaagaaattgaaagagaagagatgtatataaggtacttg
tataagctctgtgacctgcacaaagagtgtgacaactacacagaggcggcctacactttg
cttctgcacgcgaaacttctaaagtggtcagaggacgtgtgtgcagctcacctcactcag
cgggacgggttccaggcgacaacacagggacagctgaaagagcagctctaccaagaaatc
atccactactttgacaaaggcaagatgtgggaggaggccatcgccctgggcaaggaactt
gcggagcagtacgaaacagagatgtttgattatgagcagctcagtgaattgctgaaaaaa
caggcacaattttacgagaacatcgtgaaggtgataagacccaagcctgactattttgct
gttggctactatgggcaagggttcccgtcattccttcggggcaaagtgttcatttaccga
ggcaaggaatatgagcgacgggaagattttgaagctcggctgttaactcagtttccaaat
gctgaaaaaatgaagacgacgtctccaccgggcgatgacattaagacttctcccggccag
tacatccagtgcttcacagtgaagcccaagctagacttacctccgagatttcaccgaccc
gtgtctgaacagattgtaagtttttacagggtgaatgaggtacagcgattcgagtattca
cggcccatccggaaaggagagaaaaacccagacaatgaatttgcgaatatgtggattgaa
agaaccatctacactacggcctataaactgccaggaattttaaggtggtttgaagtcaaa
tctgtcttcatggtagagatcagcccactggagaatgccatcgagacaatgcagttgacc
aatgacaagatcagcagcatggtccagcagcacctggatgacccgggcctgcctatcaac
cccctgtccatgctcctgaatggcattgtggatcctgctgtcatgggtggttttgccaat
tatgagaaggctttcttcacagacagatacctgcaggagcatcctgaggcccatgggcag
attgagaagctcaaggacctgatagcctggcagattccatttttggctgaagggatcagg
attcatggagacaaagtcacagaggccctgaggccattccacgagcgcatggaagcctgc
ttcaagcaactgaaggaaaaagtggaaaagcaatatggcgtcaggaccatgccctcaggc
ttggatgacaggagaggcagccgtccacgttcaatggtgcgatctttcaccatgccatca
tcctcccggcccctgtcagtggcttccgtctcttctttctcctctgacagcactccttcc
aggccaggctctgatggatttgctctagagcctctgctgccgaagaagatgcactccagg
tcccaggacaagctagacaaggacgatccagataaagagaagaaggacaagaagaaggag
aaaaggaacagcaaacaccaagagatatttgataaggaattcaagcccgctgacagctcc
ctgcagcagtctgaggctgtgatcctttctgaaacgataagtcccctgcggccccaaaga
cccaagagccaggtgatcaatgtcattggaaatgaaaggcgcttctctgtgtctccagca
tcaccgtcctcccagcagacgccccctccagtcacaccaagagccaagctcagcttcagc
attcagcccagtctggagctgaacggcatgatgggaatggatgtggccgatgtcccaccc
cctctgcccctcaaaggcaacatggcagattatggaaatctgatggaaaaccaggatatg
atggtctcacccacatctccacctcctcctcccccacaacggcaacagccacctccactg
cccagcaaaacaccacctcctccccctccgaagacgacccgaaagcagacctcagtggac
tctggaatcgtgcagtga
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integrated database retrieval system