KEGG ORTHOLOGY: K13708

ORTHOLOGY: K13708

Entry

K13708                      KO

Symbol

DOCK1

Name

dedicator of cytokinesis protein 1

Pathway

map04510

Focal adhesion

map04666

Fc gamma R-mediated phagocytosis

map04810

Regulation of actin cytoskeleton

map05100

Bacterial invasion of epithelial cells

map05131

Shigellosis

map05135

Yersinia infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K13708  DOCK1; dedicator of cytokinesis protein 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K13708  DOCK1; dedicator of cytokinesis protein 1
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K13708  DOCK1; dedicator of cytokinesis protein 1
09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K13708  DOCK1; dedicator of cytokinesis protein 1
   05135 Yersinia infection
    K13708  DOCK1; dedicator of cytokinesis protein 1
   05100 Bacterial invasion of epithelial cells
    K13708  DOCK1; dedicator of cytokinesis protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K13708  DOCK1; dedicator of cytokinesis protein 1
Membrane trafficking [BR:ko04131]
Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    K13708  DOCK1; dedicator of cytokinesis protein 1

Other DBs

GO:	0005085 0005096

Genes

HSA:	1793(DOCK1)

PTR:	104001055(DOCK1)

PPS:	100971564(DOCK1)

GGO:	101127665(DOCK1)

PON:	100462022(DOCK1)

NLE:	100593551(DOCK1)

MCC:	700788(DOCK1)

MCF:	102131974(DOCK1)

CSAB:

103216694(DOCK1)

CATY:

105578039(DOCK1)

PANU:

101003085(DOCK1)

TGE:	112631304(DOCK1)

RRO:	104658119(DOCK1)

RBB:	108519578(DOCK1)

TFN:	117064910(DOCK1)

PTEH:

111550784(DOCK1)

CJC:	100411936(DOCK1)

SBQ:	101053057(DOCK1)

CSYR:

103254912(DOCK1)

MMUR:

105880385(DOCK1)

OGA:	100963112(DOCK1)

MMU:	330662(Dock1)

MCAL:

110298899(Dock1)

MPAH:

110337335(Dock1)

RNO:	309081(Dock1)

MCOC:

116103130(Dock1)

MUN:	110552822(Dock1) 110566065

CGE:

100773370

PLEU:

114692902(Dock1)

NGI:	103733379 103744273

HGL:	101718612(Dock1)

CPOC:

100734315(Dock1)

CCAN:

109688773 109688780(Dock1)

DORD:

105989761(Dock1)

DSP:	122126811(Dock1)

NCAR:

124984428

OCU:	100342405(DOCK1)

OPI:	105941538(DOCK1)

TUP:	102475352(DOCK1)

CFA:	486934(DOCK1)

VVP:	112928864(DOCK1)

VLG:	121484894(DOCK1)

AML:	100469133(DOCK1)

UMR:	103658181(DOCK1)

UAH:	113252052(DOCK1)

UAR:	123800053(DOCK1)

ELK:

111145075

LLV:

125085231

MPUF:

101681503(DOCK1)

ORO:	101364900(DOCK1)

EJU:	114221826(DOCK1)

ZCA:	113921179(DOCK1)

MLX:	117997741(DOCK1)

FCA:	101084320(DOCK1)

PYU:	121037487(DOCK1)

PBG:	122493380(DOCK1)

PTG:	102973006(DOCK1)

PPAD:

109252245(DOCK1)

AJU:	106987534(DOCK1)

HHV:	120244330(DOCK1)

BTA:	537203(DOCK1)

BOM:	102266570(DOCK1) 102269426

BIU:	109553009(DOCK1)

BBUB:

102412285(DOCK1)

CHX:	102174457(DOCK1)

OAS:	101117205(DOCK1)

ODA:	120873637(DOCK1)

CCAD:

122445819(DOCK1)

SSC:	100524831(DOCK1)

CFR:	102514294(DOCK1)

CBAI:

105067562(DOCK1)

CDK:	105100301(DOCK1)

VPC:	102540401(DOCK1)

BACU:

103011505(DOCK1)

LVE:	103079280(DOCK1)

OOR:	101282288(DOCK1)

DLE:	111172195(DOCK1)

PCAD:

102981826(DOCK1)

PSIU:

116741200(DOCK1)

ECB:	100055697(DOCK1)

EPZ:	103554805(DOCK1)

EAI:	106823583(DOCK1)

MYB:	102248014(DOCK1)

MYD:	102766017(DOCK1)

MMYO:

118669639(DOCK1)

MLF:	102416933 102443158

MNA:	107535162(DOCK1)

PKL:	118719583(DOCK1)

HAI:	109389001(DOCK1)

DRO:	112300245(DOCK1)

SHON:

118990558(DOCK1)

AJM:	119059478(DOCK1)

PDIC:

114497235(DOCK1)

PHAS:

123828686(DOCK1)

MMF:	118632127(DOCK1)

RFQ:	117036031(DOCK1)

PALE:

102889149(DOCK1)

PGIG:

120581257(DOCK1)

RAY:	107512566(DOCK1)

MJV:	108391051(DOCK1) 108408449

TOD:	119234129(DOCK1)

SARA:

101549316(DOCK1)

LAV:	100663543(DOCK1)

TMU:

101356962

DNM:	101412224(DOCK1)

MDO:

100020753

GAS:	123234452(DOCK1)

SHR:	100915278(DOCK1)

PCW:	110198948(DOCK1)

OAA:	103169480(DOCK1)

GGA:	423960(DOCK1)

PCOC:

116231526(DOCK1)

MGP:

100544294

CJO:	107316266(DOCK1)

NMEL:

110400523(DOCK1)

APLA:

101804708(DOCK1) 113843992

ACYG:

106038955(DOCK1)

AFUL:

116491116(DOCK1)

TGU:	100232121(DOCK1)

LSR:	110468444(DOCK1)

SCAN:

103814094(DOCK1)

PMOA:

120512725(DOCK1)

OTC:	121341636(DOCK1)

PRUF:

121350046(DOCK1)

GFR:	102031457(DOCK1)

FAB:	101813165(DOCK1)

PHI:	102102389(DOCK1)

PMAJ:

107206787(DOCK1)

CCAE:

111930975(DOCK1)

CCW:	104694938(DOCK1)

ETL:	114065397(DOCK1)

ZAB:	102062434(DOCK1)

FPG:	101923400(DOCK1)

FCH:	102045918(DOCK1)

CLV:	102083486(DOCK1)

EGZ:	104122710(DOCK1)

NNI:	104022104(DOCK1)

ACUN:

113481723(DOCK1)

TALA:

104369008(DOCK1)

PADL:

103918635(DOCK1)

ACHC:

115347969(DOCK1)

AAM:

106486689

AROW:

112966038(DOCK1)

NPD:	112949973(DOCK1)

DNE:	112992655(DOCK1)

ASN:	102372075 102377499

AMJ:	102571995(DOCK1)

CPOO:

109323984(DOCK1)

GGN:	109287709(DOCK1)

PSS:	102452082 102459389

CMY:	102933467(DOCK1)

CPIC:

101930937(DOCK1)

TST:	117880556(DOCK1)

CABI:

116837298(DOCK1)

MRV:	120368568(DOCK1)

ACS:	100554287(dock1)

PVT:	110077909(DOCK1)

SUND:

121927273(DOCK1)

PBI:	103049846 103050939 103052032

PMUR:

107285398 107288945 107288952

TSR:	106544801(DOCK1)

PGUT:

117676726(DOCK1)

VKO:	123031150(DOCK1)

PMUA:

114597381(DOCK1)

ZVI:	118096593(DOCK1)

GJA:	107106401 107106402

STOW:

125437648(DOCK1)

XLA:	108696117(dock1.L) 108697392(dock1.S)

XTR:	100497783(dock1)

NPR:	108790880(DOCK1)

RTEM:

120946747(DOCK1)

BBUF:

121006014(DOCK1)

BGAR:

122939903(DOCK1)

DRE:	572187(dock1)

SRX:	107711371 107740868

SANH:

107666886 107667825(dock1)

SGH:	107549329(dock1) 107582198 107582199

CCAR:

109092652 109101282

CAUA:

113055842(dock1) 113081086 113083532

PPRM:

120462783(dock1)

MAMB:

125255120(dock1)

IPU:	108273880(dock1)

PHYP:

113527712(dock1)

SMEO:

124388370(dock1)

TFD:	113634075(dock1)

AMEX:

103040913(dock1)

EEE:	113581978(dock1)

TRU:	101073725(dock1)

TNG:	GSTEN00019642G001 GSTEN00019645G001

LCO:	104924776(dock1)

NCC:	104941394(dock1)

CGOB:

115024368(dock1)

ELY:	117246889(dock1) 117247534

PLEP:

121958875(dock1)

SLUC:

116061081(dock1)

ECRA:

117937023(dock1)

PFLV:

114547823(dock1)

GAT:	120819850(dock1)

PPUG:

119213290(dock1)

MSAM:

119916625(dock1)

CUD:	121528183(dock1)

ALAT:

119009806(dock1)

MZE:	101464532(dock1)

ONL:	100711819(dock1)

OAU:	116328787(dock1)

OLA:	101155391(dock1)

OML:	112154096(dock1)

XMA:	102229035(dock1)

XCO:	114151906(dock1)

XHE:	116726931(dock1)

PRET:

103481563(dock1)

PFOR:

103145111(dock1)

PLAI:

106945008(dock1)

PMEI:

106915165(dock1)

GAF:	122823794(dock1)

CVG:	107085538(dock1)

CTUL:

119781919(dock1)

GMU:	124874821(dock1)

NFU:	107387527(dock1)

KMR:	108248413(dock1)

ALIM:

106516610(dock1)

NWH:	119424041(dock1)

AOCE:

111569387(dock1)

CSEM:

103381644(dock1)

POV:	109626977(dock1)

SSEN:

122759646(dock1)

HHIP:

117752559(dock1)

LCF:	108899027(dock1)

SDU:	111219899(dock1)

SLAL:

111655245(dock1)

XGL:	120794104(dock1)

HCQ:	109513368(dock1)

BPEC:

110169990 110174602

MALB:

109962987(dock1)

BSPL:

114846518(dock1)

OTW:

112241065

OMY:	110513667 110514830

OGO:

124018336

ELS:	105009268(dock1)

SFM:	108939644(dock1)

PKI:	111853665(dock1)

AANG:

118220844(dock1)

LOC:	102690670(dock1)

PSPA:

121321739 121326054

ARUT:

117415126 117418396

LCM:	102349010(DOCK1)

CMK:	103180276(dock1)

RTP:	109919487 109931733 109934020

BFO:

BBEL:

CIN:

SPU:

APLC:

SKO:	100375196(DOCK1)

DME:	Dmel_CG10379(mbc)

DER:

6555377

DSE:

6607630

DSI:	Dsimw501_GD21040(Dsim_GD21040)

DYA:	Dyak_GE10396

DAN:

6499060

DSR:

110187864

DPO:	Dpse_GA10288

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI23072

DNV:

108654859

DHE:

111602637

DVI:	116651748 6630532

CCAT:

BOD:

MDE:

SCAC:

LCQ:

AGA:	AgaP_AGAP004320

ACOZ:

AARA:

AAG:

AALB:

CQU:	CpipJ_CPIJ002759

CPII:

CNS:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:	109605795 109606159

CSET:

AGB:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

PMAC:

PXU:

PRAP:

ZCE:

HAW:

TNL:

SLIU:

OFU:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM252200

FOC:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_313508

DMK:

PVM:

PJA:

PCHN:

HAME:

PCLA:

HAZT:

EAF:

LSM:

ISC:	IscW_ISCW003358

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107369248 107369583

CSCU:

111619405

PTEP:

107455667

SDM:

118184119

BMY:	BM_BM1916(Bma-ced-5)

LOA:	LOAG_02027

TSP:

Tsp_02454

HRO:	HELRODRAFT_109536

LGI:	LOTGIDRAFT_232874

PCAN:

BGT:

GAE:

HRJ:

CRG:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:

SMM:	Smp_029990

SHX:	MS3_0013208

OVI:	T265_03901

EGL:

EGR_02998

NVE:	5507279 5520946

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_58664

AQU:

100636268

DDI:	DDB_G0284725(docD)

DPP:	DICPUDRAFT_27977

DFA:	DFA_01105(docD)

ACAN:

ACA1_067840

» show all

Reference

PMID:8657152

Authors

Hasegawa H, Kiyokawa E, Tanaka S, Nagashima K, Gotoh N, Shibuya M, Kurata T, Matsuda M

Title

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane.

Journal

Mol Cell Biol 16:1770-6 (1996)
DOI:10.1128/MCB.16.4.1770

Sequence

[hsa:1793]

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