KEGG   Mus musculus (house mouse): 64704
Entry
64704             CDS       T01002                                 
Symbol
Htra2, Omi, Prss25, mnd2
Name
(RefSeq) HtrA serine peptidase 2
  KO
K08669  HtrA serine peptidase 2 [EC:3.4.21.108]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04210  Apoptosis
mmu04215  Apoptosis - multiple species
mmu05012  Parkinson disease
mmu05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    64704 (Htra2)
   04215 Apoptosis - multiple species
    64704 (Htra2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    64704 (Htra2)
   05022 Pathways of neurodegeneration - multiple diseases
    64704 (Htra2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    64704 (Htra2)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    64704 (Htra2)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.108  HtrA2 peptidase
     64704 (Htra2)
Peptidases and inhibitors [BR:mmu01002]
 Serine peptidases
  Family S1: chymotrypsin family
   64704 (Htra2)
Chaperones and folding catalysts [BR:mmu03110]
 Other chaperones and cochaperones
  DegP / HtrA
   64704 (Htra2)
SSDB
Motif
Pfam: Trypsin_2 Trypsin PDZ_6 PDZ_2 PDZ Peptidase_S46 GRASP55_65 YmiA-like PDZ_Tricorn
Other DBs
NCBI-GeneID: 64704
NCBI-ProteinID: NP_062726
MGI: 1928676
Ensembl: ENSMUSG00000068329
UniProt: Q9JIY5
LinkDB
Position
6:complement(83028247..83031552)
AA seq 458 aa
MAALKAGRGANWSLRAWRALGGIFWRKPPLLAPDLRALLTSGTPDSQIWMTYGTPSLPAQ
VPEGFLASRADLTSRTPDLWARLNVGTSGSSDQEARRSPGSRRREWLAVAVGAGGAVVLL
LWGWGRGLSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFVVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGTSGSQRR
YIGVMMLTLTPSILIELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKL
AQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE
NT seq 1377 nt   +upstreamnt  +downstreamnt
atggctgcgctgaaagcggggcggggtgcaaactggagccttcgggcatggcgggctttg
gggggcatcttctggaggaagcctcccctgttagctcctgacctccgggctctgctgacg
tcaggaactcctgactctcagatctggatgacttatgggacccccagtctcccggcccag
gtgcctgaggggttccttgcatcacgggcagatctgacgtctaggaccccggatctctgg
gcacgattgaatgtggggacttcaggctccagtgaccaggaggcccgcaggagccctgga
agccgtcggcgcgaatggctggcggtggcggtgggcgcaggaggtgcagtggtgctgctg
ttgtggggttggggtcggggtctttccacggtgctggctgctgttcctgctccgccaccc
acttctccccggagccagtacaatttcatcgcagatgtggtggagaagacagcccctgct
gtggtctatatcgagatcctagaccggcaccctttctccggccgtgaagtccccatctca
aacggatcaggattcgtagtggcttcagatgggctcatcgttaccaacgcccacgtggtg
gctgatcggcgccgagtacgagtgaggctgcctagcggggatacttatgaggccatggtc
acagctgtggatcccgtagcagacattgccacactgaggattcaaaccaaggagcctctt
cccacactgcccctcggccgctctgctgatgtccggcaaggggagtttgttgttgccatg
ggaagcccctttgcactgcagaacacgatcacatctggtattgtcagctctgctcagcgc
ccagccagggacctgggactccctcaaaacaacgtggaatacattcagaccgatgcagct
attgattttggaaattctggtggtcccctggttaacctggatggggaggtgattggagtg
aacaccatgaaggtgacagctggaatctcctttgccatcccttctgatcgccttagggag
tttctgcatcgcggggaaaagaaaaattcctggtttggaaccagtgggtcccagcgccgc
tacattggagtgatgatgctgaccctgactcccagcatccttattgaactacagctccgt
gagccaagcttccctgatgttcagcatggtgtcctcattcataaagttatcctgggctcc
cccgcacacagggctggtctgcggcctggtgatgtgatcttggccattggggagaaattg
gcacaaaatgctgaagatgtttatgaagctgttcgaacccaatcacagctggcagtgcgg
atccggcgcggatcagagacactgaccttatatgtgacccccgaggtcacagaatga

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