Mycolicibacterium mucogenicum: C1S78_006280
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Entry
C1S78_006280 CDS
T07324
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mmuc
Mycolicibacterium mucogenicum
Pathway
mmuc00020
Citrate cycle (TCA cycle)
mmuc00630
Glyoxylate and dicarboxylate metabolism
mmuc00785
Lipoic acid metabolism
mmuc01100
Metabolic pathways
mmuc01110
Biosynthesis of secondary metabolites
mmuc01120
Microbial metabolism in diverse environments
mmuc01200
Carbon metabolism
mmuc01210
2-Oxocarboxylic acid metabolism
Module
mmuc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mmuc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mmuc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
C1S78_006280
00630 Glyoxylate and dicarboxylate metabolism
C1S78_006280
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
C1S78_006280
Enzymes [BR:
mmuc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
C1S78_006280
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
C1S78_006280
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
C1S78_006280
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
C1S78_006280
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QPG70579
UniProt:
A0A8H2JA06
LinkDB
All DBs
Position
complement(1255303..1259022)
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AA seq
1239 aa
AA seq
DB search
MSTSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHDFLRDYNPEPVTDTTDSVAAATPAPA
AAPAAPAAAPTAPAPAAAPAAPAAPAPAAPAKAAPAKAAAGPAPAEDAETQTLRGAAAAV
VKNMNASLDVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLLGYAIVQAVKQF
PNMNRYFAEVDGKPTAVTPAHTNLGLAIDLQNKDGSRQLVVAAIKRCETMQFGQFIAAYE
DIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQGAIIGAGAMEYPAEFQGA
SEERIAELGVGKLITLTSTYDHRIIQGAESGDFLRTVHHLLLDDAFFDEIFRELGIPYEP
VRWRIDNPDSIAHKNARIIELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVNTHGLTL
WDLDREFKVDGFAGKQFMKLRDVLSVLRDAYCRHVGVEYTHILEPEQQKWLQERVEVKHD
KPTVGEQKYILSKLNAAEAFETFLHTKYVGQKRFSLEGAEAVIPMMDAAIDQAAEHNLDE
VVIGMPHRGRLNVLANIVGKPYSKIFSEFEGNLNPALAHGSGDVKYHLGATGHYLQMFGD
NEIDVSLVANPSHLEAVDPVLEGLVRAKQDLLVGDEHDDSDAHGRFSIVPMMLHGDAAFA
GQGVVAETLNLALLKGYRTGGTIHIVVNNQIGFTTAPTDSRSSEYCTDVAKMIGAPIFHV
NGDDPEACAWVARLAVDFREAFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYDVIDTKRG
VRKTYTEALIGRGDISLKEAEDALRDYQGQLERVFNEVRELEKHELAPSESVESDQTIPQ
RLLTAVDKSLLARIGDAHLAVPEGFNVHPRVKPVLEKRREMAYEGKVDWAFAELLALGSM
VAEGRLIRFSGQDTQRGTFTQRHAVLIDRVTGEEFTPLQLLATNTDGTPTGGKLLIYNSA
LSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLL
PHGHEGQGPDHTSGRIERFLQVCAEGSMTVAMPSTPANYFHLLRRHGLDGIHRPLIVFTP
KSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGVGDRSKVTRVLLTSGKLYYELVARKAK
DKREDIAIVRIEQLYPLPKRRLEATLAQYPNVQQYFWVQEEPANQGAWPTFGLSLPELLP
DRLTGIKRISRRAMSAPSSGSSKVHAIEQQAIIDEAFAP
NT seq
3720 nt
NT seq
+upstream
nt +downstream
nt
gtgagcacatcaccttcaccattcggtcagaacgagtggctggtcgaagagatgtatcgc
aaattccgtgaggacccgtcctcggtggacccgagttggcacgacttcctgcgtgactac
aaccccgaacccgtcacggacacaacagattccgtagccgcggcgaccccggcgcccgcc
gccgcacccgcagccccggctgctgcgccgaccgcaccggctcccgccgcggcccctgcc
gcaccggctgccccggcccccgccgcgcctgccaaggccgcccccgccaaggccgctgcc
ggacccgcgcccgccgaggacgccgagacgcagacgctgcgcggcgccgctgccgccgtc
gtcaagaacatgaacgcgtcgctggacgtgccgaccgccacgagcgtgcgcgccatcccc
gcgaagctgatgatcgacaaccgcgtcgtcatcaacaaccacctcaagcgcacccgcggc
ggcaagatcagcttcacccatctgctgggctacgcgatcgtccaggcggtcaagcagttc
cccaacatgaaccgctacttcgccgaggtcgacggcaagccgacggccgtcacgccggcg
cacaccaacctcggtctggcgatcgacctgcagaacaaggacggttcgcgccagctcgtc
gttgcagccatcaagcgttgcgagacaatgcaattcggccagttcatcgccgcctacgag
gacatcgtccggcgtgcccgcgacggcaaactgaccgccgaggacttcagcggcgtcacc
atctcgctgaccaacccgggcaccatcggcaccgtgcattcggtgccgcgcctgatgcgc
ggtcagggcgccatcatcggcgccggtgccatggagtacccggccgagttccagggcgcc
agcgaagagcgcatcgccgagctcggcgtcggcaagctcatcaccctgacgtcgacctac
gaccaccgcatcatccagggcgccgagtccggtgacttcctgcgcaccgtgcaccacctg
ctgctcgacgacgccttcttcgacgagatcttccgcgagctgggcatcccctacgagccg
gtgcgctggcggatcgacaacccggactcgatcgcccacaagaacgcccgcatcatcgag
ttgatcgcggcctaccgcaaccgcggccacctgatggccgacatcgacccgctgcgcctc
gacaagacccgtttccgcagccaccccgacctcgacgtcaacacccacggcctgacgctg
tgggacctggaccgcgagttcaaggtcgacggtttcgccggcaagcagttcatgaagctg
cgcgacgtgctgtcggtgctgcgcgacgcctactgccgccacgtcggtgtcgagtacacc
cacatcctcgaacccgagcagcagaaatggctgcaagagcgcgtcgaggtcaagcacgac
aagcccacggtcggtgagcagaagtacatcctgtccaagctcaacgccgccgaggccttc
gagaccttcctgcacaccaaatacgttgggcagaaacgcttctcgctggaaggcgcggaa
gccgtcatcccgatgatggacgccgccatcgaccaggcggccgaacacaacctcgacgaa
gtcgtcatcggcatgccgcaccgcggccgcctcaacgtgctggccaacatcgtcggcaag
ccgtactcgaagatcttcagcgagttcgagggcaatctgaacccggcgctggcgcacggt
tctggcgacgtgaagtaccacctcggcgccaccggccactacctgcagatgttcggcgac
aacgagatcgacgtgtcgctcgtggccaaccccagtcacctcgaagccgtcgacccggtc
ctcgagggcctggtccgggccaagcaggacctgctggtcggcgacgaacacgacgacagc
gacgcgcacggccgcttctcgatcgtgccgatgatgctgcacggcgacgccgcgttcgcc
ggccagggcgtcgtggccgagacgctgaacctcgcgctgctcaagggctaccgcaccggc
ggcaccatccacatcgtcgtgaacaaccagatcggattcaccacggcgccaacggattcg
cgctccagtgagtactgcaccgacgtggccaagatgatcggcgcgccgatcttccacgtc
aacggcgacgaccccgaggcctgcgcctgggtggcccgtctcgccgtggacttccgcgag
gcgttcaagaaggacgtcgtcatcgacatgttgtgctaccgccgccgcggccacaacgaa
ggcgacgacccgtcgatgacccagccgtacatgtacgacgtcatcgacaccaagcgcggc
gtccgcaagacctacaccgaagccctcatcggccgcggtgacatctccctcaaagaggcc
gaggacgccctgcgcgactaccagggccagctcgaacgggtcttcaacgaggtccgcgag
ctcgagaagcacgagctcgcgcccagcgagtcggtggagtccgaccagaccatcccgcag
cgcctgctgaccgcggtcgacaagtcgctgctggcccgcatcggtgacgcacacctcgcg
gtgcccgagggcttcaacgtgcacccacgcgtcaagcccgtgctggagaagcgccgcgag
atggcctacgaaggcaaggtcgactgggcgttcgccgagctgctggccctgggctcgatg
gtcgccgaaggccggctcatccggttctccggtcaggacacgcagcgcggcaccttcacg
cagcggcacgcggtcctcatcgaccgcgtcaccggtgaggagttcaccccgctgcagctg
ctggccaccaacaccgacggcaccccgaccggcggcaagctgctgatctacaactcggcg
ctgtcggagttcgccgcggtcggcttcgagtacggctactcggtgggcaaccccgacgcc
atggtgctgtgggaagcccagttcggtgacttcgtcaacggcgcgcagtcgatcatcgac
gagttcatcagctccggtgaggccaagtggggccagctctccgacgtggtgctcctgctg
ccgcacggtcacgagggccagggcccggaccacacatcgggccgcatcgagcggttcctg
caggtgtgcgccgaaggttcgatgacggtcgcgatgccgtcgaccccggccaactacttc
cacctcctgcgccggcacggcctcgacggcatccaccggccgctcatcgtcttcaccccg
aagtcgatgctgcgcaacaaggccgcggtcagcgacatcaaggacttcaccgagatcaag
ttccgctcggtgctcgaagagccgacctacgaagacggcgtcggcgaccggtcgaaggtc
acccgggtgctgctcaccagcggcaagctgtactacgagctggtggcccgcaaggccaag
gacaagcgcgaggacatcgcgatcgtgcgcatcgagcagctgtacccgctacccaagcgc
cggctcgaggcgacgctggcccagtacccgaacgtgcagcagtacttctgggttcaggag
gagccggccaaccagggtgcctggccgacgttcggcctgagcctgccggagctgctgccc
gaccgcctgaccggcatcaagcgcatctcgcgccgggccatgagcgcgccgtcgtcgggc
agctcgaaggtgcacgccatcgagcagcaggccatcatcgacgaggcgttcgccccgtag
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