KEGG   Microcebus murinus (gray mouse lemur): 105856828
Entry
105856828         CDS       T07238                                 
Symbol
TRAF6
Name
(RefSeq) TNF receptor-associated factor 6 isoform X1
  KO
K03175  TNF receptor-associated factor 6 [EC:2.3.2.27]
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur04010  MAPK signaling pathway
mmur04064  NF-kappa B signaling pathway
mmur04120  Ubiquitin mediated proteolysis
mmur04140  Autophagy - animal
mmur04144  Endocytosis
mmur04380  Osteoclast differentiation
mmur04620  Toll-like receptor signaling pathway
mmur04621  NOD-like receptor signaling pathway
mmur04622  RIG-I-like receptor signaling pathway
mmur04657  IL-17 signaling pathway
mmur04722  Neurotrophin signaling pathway
mmur04936  Alcoholic liver disease
mmur05132  Salmonella infection
mmur05133  Pertussis
mmur05135  Yersinia infection
mmur05140  Leishmaniasis
mmur05142  Chagas disease
mmur05145  Toxoplasmosis
mmur05152  Tuberculosis
mmur05160  Hepatitis C
mmur05161  Hepatitis B
mmur05162  Measles
mmur05168  Herpes simplex virus 1 infection
mmur05169  Epstein-Barr virus infection
mmur05170  Human immunodeficiency virus 1 infection
mmur05171  Coronavirus disease - COVID-19
mmur05200  Pathways in cancer
mmur05222  Small cell lung cancer
mmur05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmur05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    105856828 (TRAF6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105856828 (TRAF6)
   04064 NF-kappa B signaling pathway
    105856828 (TRAF6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    105856828 (TRAF6)
   04140 Autophagy - animal
    105856828 (TRAF6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105856828 (TRAF6)
   04621 NOD-like receptor signaling pathway
    105856828 (TRAF6)
   04622 RIG-I-like receptor signaling pathway
    105856828 (TRAF6)
   04657 IL-17 signaling pathway
    105856828 (TRAF6)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105856828 (TRAF6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105856828 (TRAF6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105856828 (TRAF6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105856828 (TRAF6)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    105856828 (TRAF6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105856828 (TRAF6)
   05161 Hepatitis B
    105856828 (TRAF6)
   05160 Hepatitis C
    105856828 (TRAF6)
   05171 Coronavirus disease - COVID-19
    105856828 (TRAF6)
   05162 Measles
    105856828 (TRAF6)
   05168 Herpes simplex virus 1 infection
    105856828 (TRAF6)
   05169 Epstein-Barr virus infection
    105856828 (TRAF6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105856828 (TRAF6)
   05135 Yersinia infection
    105856828 (TRAF6)
   05133 Pertussis
    105856828 (TRAF6)
   05152 Tuberculosis
    105856828 (TRAF6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105856828 (TRAF6)
   05140 Leishmaniasis
    105856828 (TRAF6)
   05142 Chagas disease
    105856828 (TRAF6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105856828 (TRAF6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105856828 (TRAF6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmur04131]
    105856828 (TRAF6)
   04121 Ubiquitin system [BR:mmur04121]
    105856828 (TRAF6)
Enzymes [BR:mmur01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     105856828 (TRAF6)
Membrane trafficking [BR:mmur04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    105856828 (TRAF6)
Ubiquitin system [BR:mmur04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    105856828 (TRAF6)
SSDB
Motif
Pfam: TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-TRAF_2 zf-RING_5 Sina_ZnF SlyX TRAF3_RING RING_XB3-XBAT31 zf-RING_11 U-box DUF4455 DUF7310 DUF3450 DUF1664 DUF16 DUF7607 HAP1_N Med21 DUF6271 Spc29 PspA_IM30 UPF0242
Other DBs
NCBI-GeneID: 105856828
NCBI-ProteinID: XP_012594190
Ensembl: ENSMICG00000008604
UniProt: A0A8C5W1A7
LinkDB
Position
5:27394225..27420223
AA seq 533 aa
MSLLNCENSCASSQSESDCCAAMASSCGAAAKDDSVSGTASTGTLSTSFMEEIQGYDVEF
DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLETQLFPD
NFAKREILSLMVRCPNEGCLHKMELRHLEDHQAHCEFALMNCPQCQRPFQKCQINIHILK
DCPRRQVSCANCAVLMAFEDKEIHDQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPI
PCAFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSLTLTPYDPASLSRVSSGCH
PEVQNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVGELKRTIRSLEDKVAEIEAQQC
NGIYIWKIGNFGMYLKSQEEERPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISL
FVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPK
GFGYVTFMHLEALKQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDTGL
NT seq 1602 nt   +upstreamnt  +downstreamnt
atgagtctgctaaactgtgaaaacagctgtgcatccagccagtctgaaagtgactgctgt
gctgccatggccagctcctgtggcgccgcagccaaagatgacagcgtcagtggaactgcc
agcacggggaccctctccacctcctttatggaagagatccagggatatgacgtggagttt
gacccacccctggaaagcaagtatgagtgccccatctgcttgatggcactacgggaagca
gtgcaaacaccctgcggccacaggttctgcaaagcctgcatcataaaatcaataagggat
gcaggtcacaaatgtccagttgacaatgaaatactgctggaaactcaactatttcctgac
aattttgcaaaacgagagattctttctctgatggtgaggtgtccaaatgaaggttgtttg
cacaagatggaactgaggcatcttgaggatcatcaagcacattgtgagtttgctcttatg
aattgtccccaatgccaacgtcccttccaaaaatgccaaattaatattcacattctcaag
gattgtccaaggagacaggtttcttgtgcaaattgtgctgtattgatggcatttgaagat
aaagagatccatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaatacc
atgctcatcagagaacagatgcctaatcattatgacctagactgccctacagctccaatt
ccatgtgcattcagtacttttggttgccatgaaaagatgcagaggaatcacttggcacgc
cacctacaggagaacacccagtcgcacatgagaatgttggcccaggctgttcatagttta
agccttactttaactccctatgatcctgcctctctatcccgggtttcctctgggtgtcac
ccagaagtccaaaatttccaggaaaccattcaccagttagaaggtcgccttgtaagacaa
gatcatcaaattcgggagctgactgctaaaatggaaactcagagcatgtatgtaggtgag
ctcaaacgaactattcgatcccttgaggacaaagttgctgaaattgaagcacaacagtgc
aatgggatttacatctggaagattggcaactttgggatgtacttgaaatctcaagaagaa
gagagaccagttgtcattcatagccctggattctacacaggcaaacctgggtacaaactc
tgcatgcgtttgcatcttcagttaccaactgctcagcgctgtgcaaactatatatccctc
tttgtccacacaatgcaaggagagtatgacagccacctcccttggcccttccagggtaca
atacgccttacaattcttgatcagtctgaagcacctgtaaggcaaaaccatgaagagata
atggatgccaaaccagagctgcttgccttccagcgacccacaatcccacggaacccaaaa
ggttttggctatgtaacttttatgcatctggaagccctaaaacaaagaacctttattaag
gatgacacattattagtacgctgtgaggtctctacccgcttcgacatgggtagccttcgg
agggagggttttcagccacgaagtactgatacagggctatag

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