Microcebus murinus (gray mouse lemur): 105859934 Help Entry 105859934         CDS       T07238                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur00230   Purine metabolism mmur01100   Metabolic pathways mmur01522   Endocrine resistance mmur04015   Rap1 signaling pathway mmur04020   Calcium signaling pathway mmur04022   cGMP-PKG signaling pathway mmur04024   cAMP signaling pathway mmur04062   Chemokine signaling pathway mmur04072   Phospholipase D signaling pathway mmur04081   Hormone signaling mmur04082   Neuroactive ligand signaling mmur04114   Oocyte meiosis mmur04211   Longevity regulating pathway mmur04213   Longevity regulating pathway - multiple species mmur04261   Adrenergic signaling in cardiomyocytes mmur04270   Vascular smooth muscle contraction mmur04371   Apelin signaling pathway mmur04540   Gap junction mmur04611   Platelet activation mmur04713   Circadian entrainment mmur04714   Thermogenesis mmur04723   Retrograde endocannabinoid signaling mmur04724   Glutamatergic synapse mmur04725   Cholinergic synapse mmur04727   GABAergic synapse mmur04750   Inflammatory mediator regulation of TRP channels mmur04911   Insulin secretion mmur04912   GnRH signaling pathway mmur04913   Ovarian steroidogenesis mmur04914   Progesterone-mediated oocyte maturation mmur04915   Estrogen signaling pathway mmur04916   Melanogenesis mmur04918   Thyroid hormone synthesis mmur04921   Oxytocin signaling pathway mmur04922   Glucagon signaling pathway mmur04923   Regulation of lipolysis in adipocytes mmur04925   Aldosterone synthesis and secretion mmur04926   Relaxin signaling pathway mmur04927   Cortisol synthesis and secretion mmur04928   Parathyroid hormone synthesis, secretion and action mmur04934   Cushing syndrome mmur04935   Growth hormone synthesis, secretion and action mmur04970   Salivary secretion mmur04971   Gastric acid secretion mmur04972   Pancreatic secretion mmur04976   Bile secretion mmur05032   Morphine addiction mmur05163   Human cytomegalovirus infection mmur05166   Human T-cell leukemia virus 1 infection mmur05200   Pathways in cancer mmur05207   Chemical carcinogenesis - receptor activation mmur05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmur00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105859934 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105859934 (ADCY2)    04371 Apelin signaling pathway     105859934 (ADCY2)    04020 Calcium signaling pathway     105859934 (ADCY2)    04072 Phospholipase D signaling pathway     105859934 (ADCY2)    04024 cAMP signaling pathway     105859934 (ADCY2)    04022 cGMP-PKG signaling pathway     105859934 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105859934 (ADCY2)    04081 Hormone signaling     105859934 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105859934 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     105859934 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105859934 (ADCY2)    04062 Chemokine signaling pathway     105859934 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     105859934 (ADCY2)    04922 Glucagon signaling pathway     105859934 (ADCY2)    04923 Regulation of lipolysis in adipocytes     105859934 (ADCY2)    04912 GnRH signaling pathway     105859934 (ADCY2)    04913 Ovarian steroidogenesis     105859934 (ADCY2)    04915 Estrogen signaling pathway     105859934 (ADCY2)    04914 Progesterone-mediated oocyte maturation     105859934 (ADCY2)    04921 Oxytocin signaling pathway     105859934 (ADCY2)    04926 Relaxin signaling pathway     105859934 (ADCY2)    04935 Growth hormone synthesis, secretion and action     105859934 (ADCY2)    04918 Thyroid hormone synthesis     105859934 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     105859934 (ADCY2)    04916 Melanogenesis     105859934 (ADCY2)    04925 Aldosterone synthesis and secretion     105859934 (ADCY2)    04927 Cortisol synthesis and secretion     105859934 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105859934 (ADCY2)    04270 Vascular smooth muscle contraction     105859934 (ADCY2)   09154 Digestive system    04970 Salivary secretion     105859934 (ADCY2)    04971 Gastric acid secretion     105859934 (ADCY2)    04972 Pancreatic secretion     105859934 (ADCY2)    04976 Bile secretion     105859934 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     105859934 (ADCY2)    04727 GABAergic synapse     105859934 (ADCY2)    04725 Cholinergic synapse     105859934 (ADCY2)    04723 Retrograde endocannabinoid signaling     105859934 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     105859934 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     105859934 (ADCY2)    04213 Longevity regulating pathway - multiple species     105859934 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     105859934 (ADCY2)    04714 Thermogenesis     105859934 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105859934 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     105859934 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105859934 (ADCY2)    05163 Human cytomegalovirus infection     105859934 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     105859934 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105859934 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105859934 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105859934 (ADCY2) Enzymes [BR:mmur01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105859934 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  105859934 NCBI-ProteinID:  XP_012599681 Ensembl:  ENSMICG00000002952 UniProt:  A0A8B7EWI6 LinkDB All DBs Position 12:complement(18144671..18558668) Genome browser AA seq 1095 aa AA seqDB search MWQEAMRRRRYLRDRAEAVAAAAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMG SCLALLALFFAFGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWIC LVAMAYLFMCFGGTISPWDQVSFFLFIIFVVYTMLPFSMRDAVIASVLTSSSHTIVLSAC LSSTPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFE KRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADI VGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAK NCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHM EAGGVPGRVHISSVTLEHLNGAYKVEEGDGEVRDPYLKQHLVKTYFVINPKGERRSPQHL FRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQ NRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATP LPAFKYYVTCACLIFFCIFVVQILVLPKTSTFGISFGATFLLLAFILFVCFAGQLLQCSK KASPPLMWLLKSSGIIANRFWPRIFLTVVTTAIVLIMAVFNMFFLSDPEETVLPTANTSN TSFPASNNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMLVALVGYNII LLHTHAHILSHYSHVLFERPGIWKDLKTMGSVSLSIFFVTLLVLGRQNEYYCRLDFLWKN KFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDF KEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPS QEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKP QYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFV NTEMSRSLSQSNLAS NT seq 3288 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggccgtggcg gcggcggcggcgggcggcggagacgggctgccgcggtcccgggactggctgtacgagtcc tactactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggc tcctgcctcgccctgctcgccctcttcttcgccttcgggctggaagttgaagaccacgtg gcatttttaataacggttcccacagccctggcgattttctttgcgatatttatcctcgtc tgcatcgagtctgtttttaagaagctgctgcgcctcttctctttggtgatatggatctgc ctcgtggccatggcctacttgttcatgtgcttcggaggaaccatctctccctgggaccag gtatcgttcttcctcttcattatcttcgtggtgtacaccatgctgcccttcagcatgcga gatgccgtcatcgccagcgtcctcacctcctcttcccacaccatcgtgctgagcgcctgc ctgtcttcaactccgggggccaaggagcacctggtctggcagatcctggccaacgtgatc attttcatctgtgggaacctggcgggagcctaccacaagcacctcatggaacttgctctg cagcaaacatatcaggacacatgcaactgcatcaagtcccggatcaagctggaatttgaa aaacgtcagcaggagcggctgctgctgtccctgctgccggcccacatagccatggagatg aaggccgagatcatccagcggctgcagggccccaaggcggggcagatggaaaacacaaac aactttcacaacctgtacgtcaaacgacacaccaacgtcagcatcttgtacgctgacatt gttggcttcacccggctggcgagtgactgctccccgggagagctcgtccacatgctgaat gaactctttggcaagtttgatcagattgcaaaggagaacgaatgcatgagaattaaaatt ttaggagactgctactactgtgtgtcgggactgcctatatctctccccaaccatgccaaa aactgtgtgaaaatgggattggatatgtgtgaagccataaagaaagtaagggatgctacc ggcgtggacatcaacatgcgcgtgggcgtgcactctgggaatgtcctgtgcggtgtgatt ggtctgcagaagtggcagtacgacgtgtggtcacatgacgttaccttggccaaccacatg gaagctggaggggtccctggacgtgtccacatttcttctgtcaccctggagcacttgaac ggggcctacaaagtggaggagggagacggcgaagtcagggacccctacttaaaacagcac ctggtgaagacctacttcgtaatcaaccccaagggagaacgacggagtccccagcacctc ttcagacctcggcacaccctggacggagccaagatgagggcgtccgtccgcatgacccgg tacttggagtcctggggggcggccaagccctttgcacacctgcatcacagggacagcatg accacggagaacggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaa aatcgcaccttaagaaccaaatcacaaaagaaaagatttgaagaagaattgaatgaaagg atgattcaagcaattgatggaatcaatgcacaaaagcaatggctcaagtctgaagatatt cagagaatctcactgcttttttataacaaaatactagaaaaagaataccgagccacccca ctgccagcgttcaagtactacgtgacttgcgcgtgtctcattttcttctgcatctttgtc gtgcagattctcgtattaccaaaaacgtccacctttgggatttcctttggagccacgttt ctcttgctcgccttcatcctcttcgtctgctttgctggacagcttctgcaatgcagcaaa aaagcctctccccctctcatgtggcttttgaagtcctcaggcatcatcgccaaccgcttc tggccacggatctttctgaccgtcgtcaccacggccatcgtgctgatcatggctgtgttc aacatgtttttcctgagtgacccagaggaaactgtccttccaactgccaatacatcaaac acaagttttcctgcctcaaataatcaggcagcgattctgcgtgcgcaaaatttgtttttc ctcccgtacttcatatacagctgcattctgggcctgatctcctgctccgtgttcctgcgg gtgaattacgagctgaaaatgttgatcatgctggtggcgttggtgggctacaacatcatc ctgctccacactcatgcccacatcctgagtcactacagccacgtcctgtttgagaggcca ggcatttggaaagacctaaagaccatgggctctgtgtctctctctatattcttcgtcaca ctgcttgtcctgggtagacagaatgaatattactgtaggttagacttcttgtggaagaac aagttcaaaaaagagcgggaggagatagagaccatggagaacctgaaccgcgtgctgctg gagaacgtgcttcccgcccacgtcgccgagcacttcctggcccggagcctgaagaacgag gagttataccaccagtcctatgactgcgtctgcgtcatgtttgcctccattcccgacttc aaggaattttatacggaatcagacgtgaacaaggagggcttggaatgccttcggctcctg aacgagatcatcgctgactttgacgatctgctgtccaagccgaaattcagcggagttgaa aagatcaagaccatcggcagcacgtacatggcagcgacggggctgagcgccgtgcccagc caggagcatgcccaggagcccgagcggcagtacatgcacattggcaccatggtggaattt gcttttgccctggtggccaaactggacgccatcaacaagcactccttcaacgatttcaag ctgcgagtgggtattaaccacgggcctgtcatagctggtgtgattggcgctcagaagcca cagtatgacatctggggcaacaccgtcaacgtggccagtcggatggacagcaccggcgtc ctggacaaaatacaggtcaccgaggaaacgagcctcatcctgcagacgctcgggtacacg tgcacgtgtcgaggaatcatcaacgtgaaaggcaagggagacctgaagacgtactttgta aacacagaaatgtcaaggtcgctttcccagagcaacctggcatcctga

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