Microcebus murinus (gray mouse lemur): 105862871 Help Entry 105862871         CDS       T07238                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur04022   cGMP-PKG signaling pathway mmur04068   FoxO signaling pathway mmur04081   Hormone signaling mmur04140   Autophagy - animal mmur04150   mTOR signaling pathway mmur04151   PI3K-Akt signaling pathway mmur04152   AMPK signaling pathway mmur04211   Longevity regulating pathway mmur04213   Longevity regulating pathway - multiple species mmur04722   Neurotrophin signaling pathway mmur04910   Insulin signaling pathway mmur04920   Adipocytokine signaling pathway mmur04923   Regulation of lipolysis in adipocytes mmur04930   Type II diabetes mellitus mmur04931   Insulin resistance mmur04932   Non-alcoholic fatty liver disease mmur04935   Growth hormone synthesis, secretion and action mmur04960   Aldosterone-regulated sodium reabsorption mmur05010   Alzheimer disease mmur05206   MicroRNAs in cancer mmur05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mmur00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     105862871 (IRS1)    04022 cGMP-PKG signaling pathway     105862871 (IRS1)    04151 PI3K-Akt signaling pathway     105862871 (IRS1)    04152 AMPK signaling pathway     105862871 (IRS1)    04150 mTOR signaling pathway     105862871 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     105862871 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105862871 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105862871 (IRS1)    04923 Regulation of lipolysis in adipocytes     105862871 (IRS1)    04920 Adipocytokine signaling pathway     105862871 (IRS1)    04935 Growth hormone synthesis, secretion and action     105862871 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105862871 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     105862871 (IRS1)   09149 Aging    04211 Longevity regulating pathway     105862871 (IRS1)    04213 Longevity regulating pathway - multiple species     105862871 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     105862871 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     105862871 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105862871 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105862871 (IRS1)    04932 Non-alcoholic fatty liver disease     105862871 (IRS1)    04931 Insulin resistance     105862871 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  105862871 NCBI-ProteinID:  XP_012604932 LinkDB All DBs Position 8:12559340..12618561 Genome browser AA seq 1238 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAASGLGGGGGSCSGSSGLGEAGEDLSYGDAPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSARLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN GHYILSRGGNGHRYIPGAGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTHSYPEEGLEMHPMEPQGGHHR PDTSTLHTDDGYMPMSPGVAPVPSSRKSSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDLGGGPSSSSSAAPSGSSYGKLWTNGVGGHHSPALPHPKPPVESSGG KLLPCTGDYMNMSPVGDSNTSSPSGCYYGPEYPQHKPVLSYYSLPRSFKHTQRPGEPEEG ARHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGARLEPGLPHAHHHQVLQPHLP RKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQPLLHPPEPKSPGEYVNIEFGSDQ PGYLSGPVASHSSPSVRCPSQLQPTPREEETGTEEYMKMDLGPGRRAAWQESSGVEMGRV GPAPPGATSVCRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPVSYADMRTGIAAREVS LPRAATAAPSSSSAASASPAAPQGTAELAAQASLLGGPQGPGGMSAFTRVNLSPNRNQSA KVIRADPQGCRRRHSSETFCSTPSATRAGNTVPLGGGAAVGASSGGGSSSSEDGKRHSSA SFENVWLKPGELGEAPKESAQVCGAAGGLENGLNYIDLDLVKDFKQRSQERPAQPQPPLP TPPRQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ NT seq 3717 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagaccgacggcttctcggacgtgcgcaaggttggctacctgcgc aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcagggggc ccggcgcgcctggagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatcccccttgagagctgcttcaacatcaataagcgggctgactccaagaac aagcacctggtggctctctatacccgggacgagcactttgccatcgcggcggacagcgag gctgagcaagacagctggtaccaggctctcctgcagctgcacaaccgtgccaagggccac cacgatggggctgcagcatccgggctgggaggcggcgggggcagctgcagcggcagctct ggcctgggcgaggctggggaggacttgagctacggggatgcgcccccaggacccgccttc aaagaggtctggcaggtgatcctgaagcccaagggcctgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcagccgccgtggtgctgcagctaatgaacatcaggcgctgcggccactcggagaacttc ttcttcatcgaggtgggccgttccgccgtgacggggccgggggagttttggatgcaggtg gatgactcggtggtggcccagaacatgcacgagaccatcctggaggccatgcgggccatg agtgatgagttccgccctcgcagcaagagccagtcctcatccaactgctccaaccccatc agcgtccccctgcgcaggcaccatctcaacaaccccccgcccagccaggtggggctgacc cgccgatcgcgcaccgagagcatcaccgccacctccccagccagcatggtgggcggaaag ccgggttccttccgcgtccgcgcctccagcgacggcgaaggcaccatgtcacgcccggcc tcggtggatggcagtcctgtgagtcctagcaccaacaggacccacgcccaccggcatcgg ggcagcgcccggctgcaccccccactcaaccacagccgctctatccccatgccttcttct cgctgctcgccttcggccaccagcccggtcagtctgtcgtccagcagcaccagtggccac ggctccacctcggactgcctgttcccacggcggtctagtgcttctgtgtccgggtccccc agcgatggcggtttcatctcctcggacgagtatggctccagtccttgcgatttccgaagc tctttccgcagtgtcactccagattccctgggccacaccccaccggcccgtggtgaagag gagctgagcaactatatctgcatgggcggcaagggggcctccaccctgaccgcccccaac ggtcactacattttgtctaggggtggcaatggccaccgctacatcccgggagctggcttg ggcaccagtccagccttggctggggatgaagcagccagtgctgcagatctggataatcgt ttccgaaagagaactcactcggcaggcacatcccctaccatttcccaccagaagaccccg tcccagtcctcagtggcttccatcgaggagtatacggagatgatgcctgcctacccacca ggaggtggcagtggaggccgactgccgggccaccggcactccgccttcgtgcccacccac tcctacccggaggagggtctggaaatgcaccccatggagcctcaggggggccaccaccgc ccagatacctccaccctccacaccgacgatggctatatgcccatgtccccgggggtggcc ccagtgcccagcagcagaaagagcagtggggactatatgcccatgagccccaagagcgtg tctgccccccagcagatcatcaaccccatcagacgccatccccagagagtggaccccaat ggctacatgatgatgtcccccagcggcagctgctcccctgaccttggaggtgggcccagc agcagcagcagtgctgccccctctgggagcagctacgggaagctttggacaaatggtgta gggggccaccactctcccgccctgccccaccccaagcctccagtggagagcagtggtggc aagctcttgccttgcacaggtgactacatgaacatgtcgccagtgggggactccaatacc agcagcccctccggctgctactacggccctgaatacccccagcacaagccagtcctctcc tactactcattgccaaggtcctttaagcacactcagcgtcctggggagccagaggagggt gcccggcaccagcacctccgcctttcctctagctctggtcgccttctctatgctgcagcg gcagaagattcttcctcctccaccagcagcgacagccttggtgggggctactgtggggct aggctggagcctggtctcccgcatgcccaccaccatcaggtcttgcagccccatctgcct cggaaagtggacacagccgcccagaccaacagccgcctggctcggcccacgaggctatcc ctgggggatcctaaggccagcaccttacctcgggcccgagagcagcagcagcccctgctg caccctccggagcccaaaagcccaggggaatatgtgaatattgaatttgggagtgatcag cctggctatttatctggccccgtggcttcccacagctcgccttcagtcaggtgtccatcc cagctccagccaactcccagagaggaagagactggcactgaggagtacatgaaaatggac ctggggccgggccggagggcagcctggcaggagagctccggggttgagatgggcagagtg ggccccgcacctcctggggctacgagcgtttgcaggcccacccgggcagtacccagcagc cgtggcgactatatgaccatgcagatgggttgtccccgtcagagctacgtggacacctcc ccagttgccccggtcagctatgctgacatgcggacaggcattgctgcacgggaggtgagc ctgcccagggctgccacggctgctccctcctcatcctcagcagcctctgcttctcctgct gcacctcaagggacagctgagctggctgcccaagcatccctgctagggggcccacaggga cccgggggcatgagcgccttcacccgggtgaacctcagtcccaaccgaaaccagagtgcc aaagtgatccgtgcagacccacaagggtgccggaggaggcatagctccgagaccttctgc tccacacctagtgccacccgggcgggcaacacagtgcccttaggagggggggctgcagta ggggctagcagcggaggcggcagcagcagcagtgaagatgggaaacgccacagctctgct tcctttgagaatgtgtggctgaagcctggggagcttggggaagcccccaaggagtcagcc caagtgtgtggggctgctgggggtttggagaatggtcttaactacatagacctggatttg gtcaaggacttcaagcagcgctctcaggagcgccctgctcaaccacagcctcccctacca acaccccctcgtcagcccctgggcagcggggaaagcagctccacccgccgctccagtgag gatttaagcgcctatgccagcatcagtttccagaagcagccagaggaccgccagtag

DBGET integrated database retrieval system