Microcebus murinus (gray mouse lemur): 105866938
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Entry
105866938 CDS
T07238
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00061
Fatty acid biosynthesis
mmur00620
Pyruvate metabolism
mmur00640
Propanoate metabolism
mmur01100
Metabolic pathways
mmur04152
AMPK signaling pathway
mmur04910
Insulin signaling pathway
mmur04920
Adipocytokine signaling pathway
mmur04922
Glucagon signaling pathway
mmur04931
Insulin resistance
mmur04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
105866938 (ACACB)
00640 Propanoate metabolism
105866938 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
105866938 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
105866938 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
105866938 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105866938 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105866938 (ACACB)
04931 Insulin resistance
105866938 (ACACB)
Enzymes [BR:
mmur01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
105866938 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
105866938 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
105866938 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
105866938
NCBI-ProteinID:
XP_012612067
Ensembl:
ENSMICG00000043665
UniProt:
A0A8B7FSK2
LinkDB
All DBs
Position
21:complement(10878561..10991546)
Genome browser
AA seq
2460 aa
AA seq
DB search
MVLLLFLSCLVFSCLTFSWLKIWRKMTDSEPVAVSQSEAGAIRSQQPFPDSDSSEKPPQE
HGGDGGVSLPKTPQEAEPASRPRPKGSGRRRSSLPPSRQKPPRDPLSSNHVSPSPELQAN
GTGSEDPEAPDTDGLSSPVQPQGQRARSPSKEDKKQANIKKQLMTNFILGSFDECSDDED
PGAGLFRESSRKGSRASLGTLTPEVLLATGEPETLVPKMRPSMSGLHLVKRGREHKKLDL
HRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVM
VTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENP
KLPELLCKHGIAFLGPPSEAMWALGDKIACTIVAQTLQVPTLPWSGSGLTVAWTEDDLQQ
GKIITVPEDVYEKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFR
QVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATI
APLAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADV
NLPAAQLQIAMGVPLHRLKDIRLLYGESPWAVTPISFEAPSSPPLARGHVIAARITSENP
DEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMV
VALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCG
ALNVADAMFRTCMTDFLHSLERGQVLPADSLLNIVDVQLIYGGVKYILKVARQSLTMFVL
IMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLR
SPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYVKRPGVVLEAGCVV
ARLELDDPSKVHPAELFTGQLLSQQTLPILGEKLHQVFHTVLENLTNVMSGYCLPEPIFS
IKLKEWVQKLMTTLRHPSLPLLELQDIMTSVSGRIPAPVEKAVHRVMAQYASNITSVLCQ
FPSQQIATVLDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYL
HVEHHFQQAHYDKCVINLREKFKPDMSQVLDCIFSHSQVAKKNQLVIMLIDELCGPDPSL
SDELTSILNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQF
CPENLKKLILSETTIFDVLPSFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGT
CVVEFQFMLPSSHPNRMAMPISISNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDF
TRNFDEVISCFANVPRDAPLFSKARASLYSEEDCKSLREEPIHILNVAIQCADHLEDEAL
VLILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAF
QLELSRMRNFDLTAVPCANHKMHLYLGAARVKEGVEVTDHRFFVRAIIRHSDLITKEASF
EYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRY
GSRLWKLRVLQAEVKINIRQSTTGSAIPIRLFITNESGYYLDISIYEEVTDPRSGNIMFH
SFGNKQGPQHGMLINTAYVTKDLLQAKRFQAQSLGTTYIYDFPEMFRQALFKLWGSPDKY
PKDILVYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRLKTQEYPEGRDVIVIGNDITFR
IGSFGPGEDLLYLRASEMARAEGIPQIYVAANSGARIGMAEEIKHMFQVAWVDPEDPQKG
FKYLYLSPQDYTRISSLNSVHCKHIEEGGESRYVITDVIGKDDGLGVENLRGSGTIAGES
SLAYEEVVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNN
QLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPVITPTDPIDREIEFLP
SRAPYDPRWMLAGRPHPTLKGAWQSGFFDQGSFKEIMAPWAQTVVTGRARLGGIPVGVIA
VETRSVELVVPADPANLDSEVKVIQQAGQVWFPDSAYKTAQAIEDFSREKLPLLIFANWR
GFSGGMKDMYDQVLKFGAYIVDGLRKYKQPVLIYIPPYAELRGGSWVVIDATINPLCIEM
YADKESRGGVLEPEGTVEIKFRKKDLIKSMRRLDPAYKKLMEQLGAPELSDAERKELEGR
LRAREDLLLPIYHQVAVQFADLHDTPGRMLEKGVISDVLEWKTARTFLYWRLRRLLLEDQ
VRQEILQASGPLSHVHIQSMLRRWFVESEGAVKAYLWDNNQVVVQWLEQHWQAEDGLHST
IRENIKCLKHDFVLKTIEDLVQENPEVAMDCVVYLSQHISPAERAQVVHLLSNLESPASS
NT seq
7383 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgcttctttttctatcttgcctggttttctcttgcctgaccttttcctggttg
aaaatctggcggaaaatgacggactctgagccggtcgctgtgagtcaatcggaggcgggt
gccatccggagtcagcagccctttccagactcggacagctcagagaagccaccgcaagaa
cacggtggcgatggcggcgtctccctgccaaagactccccaggaggcagagccagcctcc
cgcccacgtcccaaaggctcgggtcggcggagaagctccctgccaccctcgcgccagaag
cccccaagagaccccctttcttccaaccatgtgtcaccctccccagaactgcaagccaat
gggacggggagtgaggaccccgaggccccggacaccgacggcctgtcctccccggtccag
ccccagggccagcgggcgaggtccccctccaaggaggacaagaagcaggcaaacatcaag
aaacagctgatgaccaacttcatcctgggctcctttgacgaatgctccgacgacgaggac
cccggcgccggcttgttccgtgagtcttcccggaagggcagccgggccagcctggggacc
ctgaccccagaggtgcttctggcgacaggtgaacccgagaccctggtccccaaaatgagg
ccgagcatgtctggtctccacctggtgaagaggggccgggaacacaagaagctggatctg
cacagggacttcacggtggcttccccggccgagtttgtcacacgcttcggaggggatcgg
gtcattgagaaggtgctcatcgccaacaacggcatcgccgccgtgaagtgcatgcgatcc
atccgcaggtgggcctacgagatgttccgcaatgagcgggccatccggtttgtcgtcatg
gtgacccccgaggacctcaaggccaatgcagagtacatcaagatggcagatcagtacgtc
cctgtcccgggagggccgaacaacaacaactacgccaacgtggagctgatcgtggacatc
gccaagagaatccccgtgcaggcggtgtgggctggctggggccatgcttctgaaaacccc
aaactcccggagctgctgtgcaagcatggaatcgccttcctaggccctcccagtgaggcc
atgtgggccttgggagacaagatcgcctgcaccatcgtggcccagacgctgcaggtcccc
acgctgccctggagtggaagcggtctgacggtggcgtggacagaggacgatttgcagcag
gggaaaataatcactgtccctgaagacgtctatgaaaagggttgcgtgaaagatgtcgat
gagggcttggaggcggcggaaagaattggtttccccttgatgatcaaagcgtctgaaggc
ggcggagggaagggcatccggaaggctgagagcgcagaggacttcccgatccttttcaga
caggtgcagagtgagatcccaggctcaccgatctttctgatgaagctggcccagcacgcc
cgtcacctggaggtccagatcctcgctgaccagtacgggaacgctgtgtctctgttcggg
cgagactgctccatccagcggcggcatcagaagatcatcgaggaggcaccggccaccatt
gcccctctggccgtgtttgagttcatggagcagtgtgctgtccgcctggccaagaccgtg
ggctacgtgagcgcggggacggttgaatacctctacagccaggacggcagcttccacttc
ctggagctgaaccctcgcctgcaggtggaacacccttgcacggaaatgatcgcagacgtc
aacctgccggccgcccagctgcagatcgccatgggggtgccgctgcaccggctgaaggat
atccggctcctgtacggagagtcaccgtgggcggtgacacccatctccttcgaagcccct
tcaagtccccccctcgcccgcggccacgtcattgcggccagaatcaccagtgaaaacccg
gatgaggggtttaagccgagctcagggacggtccaggaattaaatttccgcagcaacaag
aacgtgtggggttacttcagcgtggctgccgccggaggcttgcacgagttcgccgattcc
cagtttggccactgcttctcctggggagagaaccgggaagaggccatttcgaacatggtg
gtggctttgaaggagctgtccatccggggcgacttcaggaccaccgtggaatatctcatc
aacctcctggagaccgagagtttccagaacaacgacatcgacactggctggttggaccac
ctcatcgccgaaaaagtgcaggccgagaagccggacatcatgctcggggtggtgtgcggg
gccttgaacgtggccgacgcgatgttcagaacctgcatgacggatttcctgcactccctg
gagaggggccaggtcctcccagcagactcgctgctgaacatcgtggacgtgcagctcatc
tacggaggcgtcaagtacatcctcaaggtggcccggcagtctctgaccatgtttgtgctc
atcatgaacggctgccacatcgagatcgacgcccaccggctgaacgatggcgggctgctg
ctgtcctacaacgggaacagctacaccacctacatgaaggaagaggtcgacagttaccga
attaccatcggcaacaagacttgtgtgtttgagaaggagaacgatcccacggtcctgaga
tccccgtcggccgggaagctgacgcagtacacggtggaggacgggggccacgtggaggcc
gggagcagctacgcagagatggaggtgatgaagatgatcatgacgctgaacgtgcaggag
agcggccgggtgaagtacgttaagcgtccgggagttgtgctggaagcgggctgcgtggtg
gccaggctggagctcgatgacccttctaaagtgcacccggctgagctgttcacgggacag
cttctgtcccagcagacgctgcccatcctcggagagaaactgcaccaggtcttccacacc
gtcctggaaaacctcaccaacgtcatgagtggctactgtctgcccgagcctatttttagc
ataaagctgaaggaatgggtgcagaagctcatgacaaccctccggcacccgtcgctgccc
ctgctggagctgcaggacatcatgaccagcgtgtccggccgaatccccgcccccgtggag
aaggcggtccaccgcgtgatggcccagtatgccagcaacatcacctcggtgctgtgccag
ttccccagccagcagatagcgaccgtcctggactgtcacgcggccaccctgcagcggaag
gctgaccgggaggtcttcttcatgaacactcagagcatcgtgcagctggtccagagatac
cgcagtgggacccgcggctatatgaaaacagtggtgttggatctgctgcgaagatatttg
cacgtcgagcaccatttccaacaagcccactacgacaagtgtgtgataaacctccgggag
aagttcaagccagacatgtcgcaggtgctggactgcatcttctcccactcgcaggtggcc
aagaagaaccagctggtgatcatgctgattgatgagctctgtggcccagacccttccctg
tccgacgagctgacctccatcctcaacgagctcactcagctgagcaagagcgagcattgc
aaagtggccctccgggccagacaggtcctgattgcctcccacctcccctcctacgagctg
cgccacaaccaggtggagtccatcttcctgtccgccatcgacatgtacggccaccagttc
tgcccggagaacctcaagaaattaatactttcagaaacgaccatctttgacgtcctgcct
tcgttcttctatcacgctaacaaagtcgtgtgcatggcgtccttggaggtctacgtgcgt
aggggctacatcgcctacgagctgaacagcctgcagcaccggcagctcccggacggcacc
tgcgtggtggagttccagttcatgctgccctcttcccacccaaaccggatggccatgccc
atcagcatcagcaaccccgacctgctgcggcacagcacggagctcttcatggacagcggg
ttttcgcccctgtgccagcgcatgggggccatggtggccttcaggagattcgaggacttc
accaggaactttgacgaggtcatctcctgctttgccaacgtgcccagagacgcccccctc
ttcagcaaggcccgcgcctccctgtattccgaggaggactgcaagagcctccgggaagag
cccatccacatcctgaacgtggccatccagtgtgcagaccatctggaggacgaggcgctg
gtgctcatcttgcggacgttcgtacagtccaagaaaaatatccttgtggattatggactc
cgaagaatcacgttcctgattgcccaagagaaagaatttcccaagtttttcacattcaga
gcaagagatgagtttgcagaagaccgcatctaccgtcacttggagcctgccctggccttc
cagctagagctcagccggatgcgcaacttcgacctgacggccgtgccctgcgccaaccac
aagatgcacctttacctgggtgctgccagggtcaaggaaggggtggaagtgacagaccac
cggttcttcgtccgggccatcatcaggcactccgacctgattacaaaggaggcctccttc
gagtacctgcagaacgagggggagcggctgctcctggaggccatggacgagctggaggtg
gccttcaacaacaccagcgtgcgcaccgactgcaaccacatcttcctcaacttcgtgccc
accgtcatcatggacccctccaagatcgaggagtccgtgcgctccatggtcatgcgctac
ggcagccggctgtggaaactccgagtgctgcaggccgaggtcaagatcaacatccgccag
agcaccaccggcagcgccattcccatccgcctgttcatcaccaatgagtcgggctactac
ctggacatcagcatctacgaagaagtgaccgaccccagatccggaaatatcatgtttcat
tcctttggcaacaaacaagggccccagcacgggatgctgatcaatactgcctacgtcacc
aaggacctgctgcaggccaagcgattccaggcccagtccctggggaccacctacatctat
gacttcccggaaatgttcaggcaggctctctttaaactgtggggctccccagacaagtac
cccaaagacatcctggtgtacaccgagttagtgctggacccccagggccagctggtggag
atgaaccggcttcctggcggaaacgaggtaggcatggtggccttcaaaatgaggctaaag
acccaggagtatccagaagggcgggacgtgattgtcatcggcaacgacatcaccttccgc
atcgggtcctttggcccaggggaggaccttctgtacctgcgggcatccgagatggcccgg
gcagagggcatcccccaaatctacgtggcggccaacagcggggcccgcatcggcatggcg
gaggagatcaagcacatgttccaggtggcttgggtggacccagaagacccccagaaagga
tttaagtacctgtacttgagcccgcaagactacaccagaatcagctccctgaactccgtc
cactgtaaacacattgaggaaggaggagaatccagatacgtcatcacggatgtcattggg
aaggacgatggcttgggcgtggagaatctcaggggctcgggcacaatcgccggggagtcc
tccctggcttacgaagaggtcgtcaccattagcttggtgacctgccgagcgattgggatc
ggggcctacttggtgaggctgggccagcgagtgatccaggtggagaactcccacatcatc
ctcacgggggcaggtgctctcaacaaggtcctgggaagagaggtctacacatccaacaac
cagctggggggcgtgcagatcatgcattataacggcgtgtcccacatcaccgtgccggat
gactttgagggggtctatactatcctggagtggctgtcttatatgccaaaggataatcac
agcccagtccctgtcatcacacctactgaccccattgacagagaaattgaattcctccca
tccagagcgccctatgacccccggtggatgcttgcaggaaggcctcacccaactctgaag
ggggcctggcagagcggattcttcgaccagggcagcttcaaggaaatcatggcaccctgg
gcccagaccgtggtgacaggacgagcgaggctgggtgggatccccgtcggagtgatcgcc
gtagagacgcgttccgtggagttggtggtcccggcggaccccgccaacctggattccgag
gtcaaggtgatccagcaggcgggccaagtgtggttcccagactcggcctacaagacggcc
caggccatcgaggacttcagcagggagaagctgccccttctgatcttcgccaactggagg
gggttctcggggggcatgaaagacatgtacgaccaggtgctgaagttcggagcctacata
gtggacggcctcaggaagtacaagcagcctgtcctgatctacatccccccctacgcagag
ctccgggggggctcctgggtggtcatagacgccaccatcaaccccctgtgtatagagatg
tacgcagacaaggagagcagggggggtgttctggagccagagggaacggtggagattaag
ttccgaaagaaagatctgataaagtccatgcgaaggctcgacccagcttacaagaagctg
atggaacagctaggggcgcccgagctgtcggacgcggagcgcaaggagctggagggccgg
ctgcgggcgcgcgaggacctgctgctccccatctaccaccaggtggcggtgcagttcgcc
gacctccacgacacgcccggcaggatgctggagaagggcgtcatctccgacgtgctggag
tggaagacggcgcgcaccttcctgtactggcgcctgcgccgcctcctcctggaggaccag
gtccggcaggagatcctgcaggccagcggcccgctcagccacgtgcacatccagtccatg
ctgcgccgctggttcgtggagtcggagggcgccgtcaaggcctacctgtgggacaataac
caggtggtcgtgcaatggctggagcagcactggcaggcggaggatggcctgcactccacc
atccgcgagaacatcaagtgcctgaaacacgacttcgtccttaagaccatcgaagacctg
gtgcaagaaaaccctgaggtcgccatggactgcgtggtgtatctgagccagcacatcagc
ccagccgagcgggcccaggtcgttcacctgctgtctaacctggagagcccggcctccagc
tga
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integrated database retrieval system
