KEGG   Microcebus murinus (gray mouse lemur): 105878936
Entry
105878936         CDS       T07238                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur01521  EGFR tyrosine kinase inhibitor resistance
mmur01522  Endocrine resistance
mmur04010  MAPK signaling pathway
mmur04012  ErbB signaling pathway
mmur04014  Ras signaling pathway
mmur04062  Chemokine signaling pathway
mmur04068  FoxO signaling pathway
mmur04072  Phospholipase D signaling pathway
mmur04150  mTOR signaling pathway
mmur04151  PI3K-Akt signaling pathway
mmur04380  Osteoclast differentiation
mmur04510  Focal adhesion
mmur04517  IgSF CAM signaling
mmur04540  Gap junction
mmur04550  Signaling pathways regulating pluripotency of stem cells
mmur04630  JAK-STAT signaling pathway
mmur04650  Natural killer cell mediated cytotoxicity
mmur04660  T cell receptor signaling pathway
mmur04662  B cell receptor signaling pathway
mmur04664  Fc epsilon RI signaling pathway
mmur04714  Thermogenesis
mmur04722  Neurotrophin signaling pathway
mmur04910  Insulin signaling pathway
mmur04912  GnRH signaling pathway
mmur04915  Estrogen signaling pathway
mmur04917  Prolactin signaling pathway
mmur04926  Relaxin signaling pathway
mmur04935  Growth hormone synthesis, secretion and action
mmur05034  Alcoholism
mmur05160  Hepatitis C
mmur05161  Hepatitis B
mmur05163  Human cytomegalovirus infection
mmur05165  Human papillomavirus infection
mmur05200  Pathways in cancer
mmur05203  Viral carcinogenesis
mmur05205  Proteoglycans in cancer
mmur05206  MicroRNAs in cancer
mmur05207  Chemical carcinogenesis - receptor activation
mmur05208  Chemical carcinogenesis - reactive oxygen species
mmur05210  Colorectal cancer
mmur05211  Renal cell carcinoma
mmur05213  Endometrial cancer
mmur05214  Glioma
mmur05215  Prostate cancer
mmur05220  Chronic myeloid leukemia
mmur05221  Acute myeloid leukemia
mmur05223  Non-small cell lung cancer
mmur05224  Breast cancer
mmur05225  Hepatocellular carcinoma
mmur05226  Gastric cancer
mmur05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105878936 (GRB2)
   04012 ErbB signaling pathway
    105878936 (GRB2)
   04014 Ras signaling pathway
    105878936 (GRB2)
   04630 JAK-STAT signaling pathway
    105878936 (GRB2)
   04068 FoxO signaling pathway
    105878936 (GRB2)
   04072 Phospholipase D signaling pathway
    105878936 (GRB2)
   04151 PI3K-Akt signaling pathway
    105878936 (GRB2)
   04150 mTOR signaling pathway
    105878936 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105878936 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105878936 (GRB2)
   04540 Gap junction
    105878936 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    105878936 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    105878936 (GRB2)
   04660 T cell receptor signaling pathway
    105878936 (GRB2)
   04662 B cell receptor signaling pathway
    105878936 (GRB2)
   04664 Fc epsilon RI signaling pathway
    105878936 (GRB2)
   04062 Chemokine signaling pathway
    105878936 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105878936 (GRB2)
   04912 GnRH signaling pathway
    105878936 (GRB2)
   04915 Estrogen signaling pathway
    105878936 (GRB2)
   04917 Prolactin signaling pathway
    105878936 (GRB2)
   04926 Relaxin signaling pathway
    105878936 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    105878936 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105878936 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105878936 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    105878936 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105878936 (GRB2)
   05206 MicroRNAs in cancer
    105878936 (GRB2)
   05205 Proteoglycans in cancer
    105878936 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    105878936 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    105878936 (GRB2)
   05203 Viral carcinogenesis
    105878936 (GRB2)
   05231 Choline metabolism in cancer
    105878936 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105878936 (GRB2)
   05225 Hepatocellular carcinoma
    105878936 (GRB2)
   05226 Gastric cancer
    105878936 (GRB2)
   05214 Glioma
    105878936 (GRB2)
   05221 Acute myeloid leukemia
    105878936 (GRB2)
   05220 Chronic myeloid leukemia
    105878936 (GRB2)
   05211 Renal cell carcinoma
    105878936 (GRB2)
   05215 Prostate cancer
    105878936 (GRB2)
   05213 Endometrial cancer
    105878936 (GRB2)
   05224 Breast cancer
    105878936 (GRB2)
   05223 Non-small cell lung cancer
    105878936 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105878936 (GRB2)
   05160 Hepatitis C
    105878936 (GRB2)
   05163 Human cytomegalovirus infection
    105878936 (GRB2)
   05165 Human papillomavirus infection
    105878936 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    105878936 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105878936 (GRB2)
   01522 Endocrine resistance
    105878936 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmur04131]
    105878936 (GRB2)
Membrane trafficking [BR:mmur04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    105878936 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 105878936
NCBI-ProteinID: XP_012634253
Ensembl: ENSMICG00000007414
UniProt: A0A8C5XI50
LinkDB
Position
16:6715199..6805426
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagagtgtgatcaaaattggtacaaggcagag
ctcaatggaaaggacggcttcatccccaagaactacatagaaatgaagccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacaacggcacgac
ggggcctttcttatccgagagagtgagagtgctcctggggacttctctctctctgtcaag
tttggaaatgacgtgcagcacttcaaggtgctccgagatggagctggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattatcacagatccacatctgtc
tccagaaaccagcagatattcctgcgggacatagaacaggtgccacagcagccaacatac
gtccaggccctctttgactttgacccccaggaggatggcgagctgggcttccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaagggggcttgccacggg
cagaccggcatgtttccccgcaattacgtcaccccagtgaaccggaacgtctaa

DBGET integrated database retrieval system