Mycobacteroides abscessus subsp. massiliense GO 06: MYCMA_0974
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Entry
MYCMA_0974 CDS
T02177
Name
(GenBank) pyruvate dehydrogenase E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mmv
Mycobacteroides abscessus subsp. massiliense GO 06
Pathway
mmv00010
Glycolysis / Gluconeogenesis
mmv00020
Citrate cycle (TCA cycle)
mmv00620
Pyruvate metabolism
mmv00785
Lipoic acid metabolism
mmv01100
Metabolic pathways
mmv01110
Biosynthesis of secondary metabolites
mmv01120
Microbial metabolism in diverse environments
mmv01200
Carbon metabolism
mmv01210
2-Oxocarboxylic acid metabolism
Module
mmv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MYCMA_0974
00020 Citrate cycle (TCA cycle)
MYCMA_0974
00620 Pyruvate metabolism
MYCMA_0974
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MYCMA_0974
Enzymes [BR:
mmv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MYCMA_0974
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AFN63123
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Position
2995729..2998725
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AA seq
998 aa
AA seq
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MTTEFARQDLAGNSSAPSPSENPERVRVIREGVASYLPDIDPDETGEWLESFDGLLARSG
PARARYLMLRLLERANAGRVAIPALTSTDYVNTIPTENEPWFPGDEDTERRFRAWIRWNA
AIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGNAHPGGGDQVFIQGHASPGIYA
RAFLEGRLTTDQLDGFRQEKSHPGGGLPSYPHPRLMPDFWQFPTVSMGLGPMNAIMQARF
NHYLRDRGIKDTSDQRVWAFLGDGEMDEPESRGLAHIAATEGLDNLTFVINCNLQRLDGP
VRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTADGDYQTYKA
NDGAYVREHFFGRDPRTKELVKDLTDAQVWNLKRGGHDYRKVYAAYRAATEHKGQPTVIL
AKTIKGYTLGKHFEGRNATHQMKKLTLDDLKDFRDKQRIPISDAQLEENPYLPPYYHPGP
EAPEIRYMLDRRRALGGFVPSRRTTSRPLTLPGSEIYDSIKKGSGKQEVATTMALVRTFK
ELLRDKNIGNRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDAELMLAYKESQQGQ
ILHEGINEAGSTASFTAVGTAYSTHDEPMIPLYIFYSMFGFQRTGDGLWAAADQMARGFV
LGATAGRTTLTGEGLQHADGHSLLLASTNPAVVAYDPAFAYEIAHIVEHGLQRMYGENSE
NVYFYITLYNEPYVQPAEPENVDAEGILRGIYKFRAAPEARTHRANILASGVSVPDALRA
ADLLAEQWDVAADVWSVTSWGELNRDGLAIDHQALRHPDRPKGVPYVTKALEGAQGPKVA
VSDWMHAVPEQIRPWVPGTYRTLGADGFGISDTRPAARRFFNTDAESVVVAVLEALADEG
SVDRQVAVTAAAQYKIDDVSAADVSYKDTGSRVXPPPPRRMPKCADFEPISAHLGMLALF
VDTNCTNRYSRGRSLTSPGRNPPCGSPFSLAQHFWASA
NT seq
2997 nt
NT seq
+upstream
nt +downstream
nt
ttgaccacggagttcgctcgccaggatctggccggaaattcaagtgcgccaagtccatcc
gagaatccagaacgtgtccgagtgatccgcgaaggtgtcgcgtcgtacctgccggacatc
gatccggacgagacgggcgaatggctggagtcctttgacggcctgctggcccgctcgggg
ccggcccgggcccggtacctgatgctgcggctgctggagcgggcgaacgcgggccgcgtg
gccatccccgcgctgacgtccaccgactacgtcaacaccatccccaccgagaacgagccg
tggttccccggcgatgaggacaccgagcgccgttttcgtgcgtggatccgctggaatgcc
gcgatcatggtgcaccgcgcgcagcgcccaggcgtgggcgtgggcggacacatctcgacc
tatgcctcctcggccgccctctacgaggtcggtttcaatcacttctttcggggaaatgcc
cacccgggcggaggcgaccaggtattcatccagggccacgcctcccccggcatctacgcc
cgcgccttcctggagggccggctcaccaccgatcagctggacggattccgtcaggagaag
agccaccccggcggcggcctgccctcctacccgcacccgcgcctgatgcccgatttctgg
cagttcccaacggtttccatgggcctgggaccgatgaacgcgatcatgcaggcgcggttc
aaccactaccttcgcgaccgcggcatcaaggacacctccgatcagcgggtgtgggccttc
ctcggcgacggcgaaatggacgaacccgaatcgcgcggcctggcacatatcgccgcgacc
gagggcctggacaacctgacgttcgtcatcaactgcaacctgcagcgtctggacggcccg
gtgcgcggcaacggcaagatcatccaggagctggagtccttcttccgcggcgccggctgg
aatgtcatcaaggtggtgtggggccgcgaatgggatgcactgctgcacgccgaccgggac
ggcgcactggtgaatctgatgaacaccaccgccgacggcgactaccagacctacaaggcc
aatgacggtgcctacgtccgcgaacacttcttcgggcgcgatccgcgcaccaaggaactg
gtgaaagaccttaccgacgcccaggtttggaacctcaagcgcggcggccacgactaccgc
aaggtatacgccgcctaccgcgcggccaccgagcacaagggccagccaacggtcatcctg
gccaagaccatcaagggctacacgctgggcaagcacttcgagggccgcaacgccacccac
cagatgaagaagctgacgctggatgacctgaaggacttccgcgacaagcagcgcatcccg
atctcggacgcccagctcgaagagaacccctatctgccgccgtactaccaccccggcccc
gaggctccggaaatccgctacatgctggaccggcgccgcgccctgggtggctttgtgccg
tcgcggcgcaccacatcgcgtccgctcacgctaccgggctcggagatctacgactcgatc
aagaagggctcgggcaagcaagaggtcgccaccaccatggcgttggtgcgtaccttcaag
gaactgttgcgcgacaagaacattggtaaccgcatcgttcccatcatccccgacgaggcc
cgcaccttcggcatggactcctggttcccgtcgctgaagatctacaaccgcaacggccag
ctgtacacctcggtggatgccgaattgatgttggcctacaaggaaagccagcagggccag
atcctgcatgagggcatcaacgaggctggatcgacggcctcgttcaccgcggtgggcacg
gcgtactcgacccacgacgagccgatgatcccgctgtacatcttctattcgatgttcgga
ttccagcgcaccggcgacggcctgtgggccgcggccgaccagatggcccgcggcttcgtg
ctgggcgcgacggcgggccgcaccaccctcaccggcgagggcctgcagcatgccgacggt
cactcgctgctactggcgagcaccaatcccgctgtggtggcttacgatccggcgttcgcg
tacgagatcgcgcacatcgtggagcatggcctgcagcggatgtacggcgagaacagcgag
aacgtgtacttctacatcacgctgtacaacgagccgtacgtgcagccggccgagccggag
aacgtcgatgccgagggcattctgcgcggcatctataagttccgcgcggcgcccgaggcg
cgcacgcaccgggccaacatcctggcctccggggtgtcggtgcccgacgcgctgcgggct
gcggacctgttggccgaacagtgggatgtggcggccgacgtgtggtcggtgacctcgtgg
ggtgagctcaaccgcgacggcctggcgatcgatcaccaggcgctgcgtcacccggaccgc
cccaaaggggtgccatacgtgacgaaggcactggagggtgcccagggccccaaggtggcg
gtctcggactggatgcacgcggtgcccgagcagatcaggccgtgggtgcccgggacgtac
cgcacgctgggcgccgatgggttcggcatctccgacacccgtcccgccgcacgccggttc
ttcaacaccgatgccgagtcggtcgtcgtcgcggtgctcgaggcattggccgacgagggt
tcggtcgaccgccaggtcgccgtcacggcggccgcccagtacaagatcgatgatgtgtcg
gccgccgacgtctcgtataaggacaccggcagccgcgtacsscccccccccccgcgacgc
atgcccaaatgtgcggatttcgagccgatttccgcacatttgggcatgctcgctcttttt
gtcgacaccaattgtactaatcggtacagtcgagggcgctcgctcacatctcccggaagg
aatccaccatgcggttcaccgttctcactggcacagcacttctgggcatcggcttga
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