Myotis myotis (greater mouse-eared bat): 118673043
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Entry
118673043 CDS
T07220
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00140
Steroid hormone biosynthesis
mmyo00980
Metabolism of xenobiotics by cytochrome P450
mmyo01100
Metabolic pathways
mmyo05204
Chemical carcinogenesis - DNA adducts
Module
mmyo_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
118673043 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
118673043 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
118673043 (HSD11B1)
Enzymes [BR:
mmyo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
118673043 (HSD11B1)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
Shikimate_DH
Pyr_redox_2
2-Hacid_dh_C
NAD_binding_2
Pyr_redox_3
AdoHcyase_NAD
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
118673043
NCBI-ProteinID:
XP_036199323
LinkDB
All DBs
Position
Unknown
AA seq
292 aa
AA seq
DB search
MACMKNYLLPILGIFLAYYYYSADEEFKPEMLQGKKVIVTGASKGIGKEMAYHLAKMGAH
VMVTARSEEALKKIVSNCLKYGAASAHYIAGTMEDMTFAEQFIAKAGKILGGLDMLILNH
ITSATMEPFAGDIHLVRRSMEVNYISYVVMSMAALPMLKQSNGSIVVVSSMAGKMASPLV
APYSASKFALDGFFSSIRTEFSVTKVNVSITLCILGLIDTDSAMKAVSGILNAEAAPKED
CALEIIKGGALRQEEVYYGKIGWTSLLLKNPGRRILEFLSLRNYNMEKFINN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttgtatgaaaaactatctcctacccattctggggatcttcttggcctactactac
tattccgcggatgaggaattcaaaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggattggaaaagagatggcctatcatctggcgaagatgggagcccac
gtgatggtgacagcgaggtcagaagaagctctaaagaagatagtatccaactgcttgaag
tatggagcagcctcagcacactacattgctggcaccatggaggacatgaccttcgcagag
caatttattgccaaagctggaaagatcttgggaggactagacatgctcattctcaatcac
atcaccagcgctaccatggaaccatttgctggtgatatccacttagtgcgcagaagcatg
gaggtcaactacatcagttatgtggtcatgagtatggctgccctacccatgctgaagcag
agcaacggaagcattgtcgttgtctcctccatggctgggaaaatggctagtccacttgtt
gctccctattctgcaagcaagtttgctctcgatgggtttttctcctccatcaggacggaa
ttttcagtgaccaaggtcaatgtgtcaatcactctctgtatcctcggcctcatagacaca
gactcagccatgaaggcagtgtctgggatactcaacgccgaggcagctccaaaggaagac
tgtgccctggagatcatcaaagggggagctctacgccaagaggaagtgtattatggcaaa
ataggatggaccagtctcctgctgaaaaatccagggaggaggatcctggaattcctcagc
ctacgaaattataatatggaaaaatttataaacaactag
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