Mycolicibacterium neoaurum VKM Ac-1815D: D174_20615
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Entry
D174_20615 CDS
T02959
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mne
Mycolicibacterium neoaurum VKM Ac-1815D
Pathway
mne00020
Citrate cycle (TCA cycle)
mne00630
Glyoxylate and dicarboxylate metabolism
mne00785
Lipoic acid metabolism
mne01100
Metabolic pathways
mne01110
Biosynthesis of secondary metabolites
mne01120
Microbial metabolism in diverse environments
mne01200
Carbon metabolism
mne01210
2-Oxocarboxylic acid metabolism
Module
mne_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mne_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mne00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
D174_20615 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
D174_20615 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
D174_20615 (kgd)
Enzymes [BR:
mne01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
D174_20615 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
D174_20615 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
D174_20615 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
D174_20615 (kgd)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AHC26807
UniProt:
V5XFL0
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All DBs
Position
4346291..4350124
Genome browser
AA seq
1277 aa
AA seq
DB search
MESRRKAAVSSAPSPFGQNEWLVEEMYRKFREDPSSVDSSWHEFLVDYAPEPVDGGSEPA
KSAAPAPTTTNKTTTNTTAAPSSNGSAPAKPAAPADKPAKSAAKSDTTSDTKPESKPTQK
PAEKPAEKPAAKAEPAKPKTPTAAPATDDQTAVLRGAAAAVVKNMNFSLEVPTATSVRAI
PAKAMIDNRVVINNHLKRTRGGKISFTHLLGYAIVQAVKKFPNMNRHFAEVDGKPNVVTP
AHTNLGLAIDLPGKDGNRTLVVAAIKKCETMAFGQFIAAYEDIVRRARDGKLTAEDFGGV
TISLTNPGTIGTVHSVPRLMRGQGAIIGAGAMEYPAEFQGASEERIAELGVGKLITLTST
YDHRIIQGAESGDFLRTVHTLLLDDEFYDEIFRELGIPYEPVRWRTDNPDSIFDKNARII
ELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVLTHGLTLWDLDREFKVDGFAGAEYKK
LRDVLSVLRDAYCRHVGVEYTHILEPEQQRWIQERVETKHDKPTVAEQKYILSKLNAAEA
FETFLQTKYVGQKRFSLEGAETVIPMMDAAIDQAAEHGLDEVVIGMPHRGRLNVLANIVG
KPYSQIFSEFEGNLNPSQAHGSGDVKYHLGATGTYLQMFGDNDIAVSLVANPSHLEAVDP
VLEGLVRAKQDMIDFEAGNEQPAFSVVPMMLHGDAAFAGQGVVAETLNLALLRGYRTGGT
IHIIVNNQIGFTTSPHDSRSSEYCTDVAKMVGAPIFHVNGDDPEACVWVAKLAMDFRQKF
NKDVVIDMLCYRRRGHNEGDDPSMTQPGMYDVIDTKRGVRKSYTEALIGRGDISMKEAED
ALRDYQGQLERVFNEVRELEKHEIEPSESVEADQQTPKGLNTAVDKSVLARIGDAHLAVP
EGFNVHPRVQPVLDKRREMAYEGKVDWAFGELLAIGSLVSEGKTVRLTGQDVRRGTFTQR
HAVIIDRKTGAEFTPIDLLTTDADGNPNGGRLEVYDSALSEFAAVGFEYGYSVGNPEAIV
LWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQV
CAEGSMTVAVPSTPANYFHLLRRHALDGIHRPLIVFTPKSMLRNKAAVSEVRDFTEIKFR
SVLEEPTYEDGDGDRSKVKRVLLTSGKIYYELVARKAKEKRDDIAIVRIEQLYPLPRRRL
NATLDQYPNVEQYFWVQEEPANQGAWPTFGLSLPELLPEKLTGIKRISRRAMSAPSSGSS
KVHAVEQQEILDEAFAP
NT seq
3834 nt
NT seq
+upstream
nt +downstream
nt
atggaatcgaggcgaaaagctgctgtgagcagtgcaccttcacccttcggacaaaatgag
tggctcgtcgaagagatgtatcgcaagttccgcgaggatccttcgtcggtcgattcgagt
tggcacgagttcctcgtggactacgcgccggaaccggtcgacgggggcagcgagcccgcc
aagagcgcagcgcctgccccgaccaccaccaacaagaccaccaccaacacgaccgccgcc
ccctcctccaacggctccgctcccgccaagccggctgccccggccgacaagcccgccaag
tccgcggccaagtcggacaccacgtcggacaccaagccggaatcgaagcccacccagaag
ccggcggaaaagcccgccgagaagcctgctgcgaaggccgaaccggccaagcccaagacg
cccactgccgcgccggccaccgatgaccagaccgccgtcctgcgcggtgcggccgccgcc
gtcgtgaagaacatgaacttctcgctggaggtgcccaccgccaccagcgtgcgggccatt
ccggccaaggcaatgatcgacaaccgcgtggtcatcaacaaccacctcaagcgcacccgc
ggcggcaagatcagcttcacccaccttctcggctacgccatcgtgcaggcggtcaagaag
ttccccaacatgaaccggcacttcgccgaggtcgacggcaagccgaatgtggtcacaccg
gctcacacgaatctcggcctggccatcgacctgcccggcaaggacggcaaccgcacgctg
gtggtcgccgccatcaagaagtgcgagacgatggccttcgggcagttcatcgccgcctac
gaggacatcgtccggcgcgcccgcgacggcaagctcaccgccgaggacttcggcggtgtc
accatctcgctgaccaaccccggcaccatcggcacggtgcactcggtgccgcggctgatg
cgcggccagggcgccatcatcggcgcaggcgccatggagtaccccgccgaattccagggc
gcctccgaggagcgcatcgccgaactgggtgtgggcaaactgatcacgctcacgtcgacc
tatgaccaccgcatcatccagggtgcggagtccggcgacttcctgcggaccgtgcacacc
ctgctgctcgacgacgagttctacgacgagatcttccgcgaactcggtatcccctacgag
ccggtccggtggcgcaccgacaacccggactcgatcttcgacaagaacgcccggatcatc
gagctgatcgcggcctaccgcaaccgcgggcatctgatggccgatatcgatccgctccgg
ttggacaagacgcggttccgcagccaccccgacctcgacgtgctgacccacggcctcacg
ctgtgggacctggaccgcgagttcaaggtcgacgggttcgccggcgccgagtacaagaag
ctgcgcgatgtgctctcggtgctgcgcgacgcctactgccgccatgtcggggtcgagtac
acccacatcctggagcccgagcagcagcgctggatccaggagcgcgtggagaccaagcac
gacaagcccacggtcgccgagcagaagtacatcctgagcaagctcaacgccgcagaggcc
ttcgagacgttcctgcagaccaaatacgtcgggcagaagcgcttctcgctggagggtgcg
gagaccgtcatcccgatgatggatgccgcgatcgaccaggcggccgagcacggtctcgac
gaggtcgtcatcggtatgccgcaccgcggccggctcaacgtgctggccaatatcgtcggc
aagccctacagccagatcttcagcgagttcgagggcaacctgaacccgagccaggcccac
ggttccggtgacgtgaagtaccacctcggtgccaccggcacgtacctgcagatgttcggc
gacaacgatatcgccgtctcgctggtcgccaacccgagccacctggaggccgtcgacccg
gtcctggagggtctggtccgggccaagcaggacatgatcgacttcgaggccggcaacgag
cagccggcgttctcggtggtgccgatgatgttgcacggcgatgccgccttcgcaggccag
ggtgtggtcgccgagacgctgaacctggcgctgctgcgcgggtaccgcaccggcggcacc
atccacatcatcgtcaacaaccagatcggtttcaccacctcgccgcacgactcgcgctcc
agcgagtactgcaccgacgtggccaagatggtcggcgcgccgatcttccacgtcaacggc
gatgatcccgaggcgtgtgtgtgggtggccaagctggccatggacttccgccagaagttc
aacaaggacgtcgtcatcgacatgttgtgttaccgccgccgcggccacaacgagggtgac
gacccgtcgatgacccagcccggcatgtacgacgtcatcgacaccaagcgcggtgtccgc
aagtcctacaccgaagcgctgatcggccgtggtgacatctcgatgaaggaggccgaggac
gcgctgcgcgactaccagggccaactggagcgggtgttcaacgaggtccgtgagctggag
aagcacgagatcgagccgagcgaatcggtagaggccgaccagcagacgcccaagggcctc
aacaccgccgtcgacaagtccgtgctggcccgcatcggcgacgcccacctggccgtaccg
gagggcttcaacgtgcacccgcgggtgcagccggtgctcgacaagcgtcgcgagatggcc
tacgagggcaaggtcgactgggcgttcggcgaactgctggccatcggatcgcttgtctcc
gaaggcaagacggttcggctgaccggccaggacgtgcgccgcggcaccttcacccagcgg
cacgcggtgatcatcgaccgcaagaccggtgcggagttcacccccatcgatctgctgacc
accgacgccgacggcaaccccaacggcggccggctcgaggtgtacgactcggcgctgtcg
gagttcgcggcggtcggcttcgaatacggctactcggtgggcaaccctgaggcgatcgtg
ttgtgggaggcccagttcggcgacttcgtcaacggcgcccagtccatcatcgacgagttc
atctcctccggtgaggccaagtggggtcagctctccgacgtcgtgctgctgctgccgcat
ggccacgagggccagggccccgaccacacctcggggcggatcgagcgtttcctgcaggta
tgcgccgaggggtcgatgaccgtcgcggtgccgtccacgccggccaactatttccacctg
ttgcgccgccacgcgctcgacggcatccatcggccgctgatcgtcttcaccccgaagtcg
atgctgcgcaacaaggccgcggtctccgaggtacgcgatttcaccgagatcaagttccgc
tcggtgctcgaggagccgacctacgaggacggcgacggcgaccggtcgaaggtcaagcgc
gtgctgctgaccagcggcaagatctactacgagctggtcgcgcgcaaggccaaggagaag
cgcgacgatatcgccatcgtgcgtatcgagcagctctacccgctgccccggcgccggctc
aacgcgacgctggaccagtacccgaatgtcgagcagtacttctgggtgcaggaggagccg
gccaaccagggtgcgtggccgaccttcgggctgtccctgccggagttgttgcccgagaag
ctgaccggcatcaagcggatctcgcggcgtgcgatgagcgcgccgtcgtccgggtcgtcg
aaggtccatgccgtcgaacagcaggagatcctcgacgaggcgttcgcgccctga
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