Macaca nemestrina (pig-tailed macaque): 105468105 Help Entry 105468105         CDS       T08765                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni01524   Platinum drug resistance mni04115   p53 signaling pathway mni04210   Apoptosis mni04215   Apoptosis - multiple species mni04217   Necroptosis mni04620   Toll-like receptor signaling pathway mni04621   NOD-like receptor signaling pathway mni04622   RIG-I-like receptor signaling pathway mni04623   Cytosolic DNA-sensing pathway mni04625   C-type lectin receptor signaling pathway mni04657   IL-17 signaling pathway mni04668   TNF signaling pathway mni04932   Non-alcoholic fatty liver disease mni04936   Alcoholic liver disease mni05010   Alzheimer disease mni05016   Huntington disease mni05022   Pathways of neurodegeneration - multiple diseases mni05132   Salmonella infection mni05134   Legionellosis mni05142   Chagas disease mni05145   Toxoplasmosis mni05152   Tuberculosis mni05160   Hepatitis C mni05161   Hepatitis B mni05162   Measles mni05163   Human cytomegalovirus infection mni05164   Influenza A mni05165   Human papillomavirus infection mni05167   Kaposi sarcoma-associated herpesvirus infection mni05168   Herpes simplex virus 1 infection mni05169   Epstein-Barr virus infection mni05170   Human immunodeficiency virus 1 infection mni05200   Pathways in cancer mni05203   Viral carcinogenesis mni05416   Viral myocarditis mni05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mni00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105468105 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105468105 (CASP8)    04215 Apoptosis - multiple species     105468105 (CASP8)    04217 Necroptosis     105468105 (CASP8)    04115 p53 signaling pathway     105468105 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105468105 (CASP8)    04621 NOD-like receptor signaling pathway     105468105 (CASP8)    04622 RIG-I-like receptor signaling pathway     105468105 (CASP8)    04623 Cytosolic DNA-sensing pathway     105468105 (CASP8)    04625 C-type lectin receptor signaling pathway     105468105 (CASP8)    04657 IL-17 signaling pathway     105468105 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105468105 (CASP8)    05203 Viral carcinogenesis     105468105 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105468105 (CASP8)    05161 Hepatitis B     105468105 (CASP8)    05160 Hepatitis C     105468105 (CASP8)    05164 Influenza A     105468105 (CASP8)    05162 Measles     105468105 (CASP8)    05168 Herpes simplex virus 1 infection     105468105 (CASP8)    05163 Human cytomegalovirus infection     105468105 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     105468105 (CASP8)    05169 Epstein-Barr virus infection     105468105 (CASP8)    05165 Human papillomavirus infection     105468105 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105468105 (CASP8)    05134 Legionellosis     105468105 (CASP8)    05152 Tuberculosis     105468105 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105468105 (CASP8)    05142 Chagas disease     105468105 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105468105 (CASP8)    05016 Huntington disease     105468105 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     105468105 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105468105 (CASP8)    05416 Viral myocarditis     105468105 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105468105 (CASP8)    04932 Non-alcoholic fatty liver disease     105468105 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105468105 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mni01002]     105468105 (CASP8) Enzymes [BR:mni01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105468105 (CASP8) Peptidases and inhibitors [BR:mni01002]  Cysteine peptidases   Family C14: caspase family    105468105 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DED PYRIN Peptidase_C14 Motif Other DBs NCBI-GeneID:  105468105 NCBI-ProteinID:  XP_011716380 Ensembl:  ENSMNEG00000039649 LinkDB All DBs Position Unknown AA seq 276 aa AA seqDB search MDFNRNLYDIGEQLDSEELASLKFLSLDCIPQRKQEPIKDALMLFQRLQEKRMLEENNLS FLKELLFRINRLDLLTTYLNTRKEEMERELQAPGRAQISAYRVMLYQISEEVGRSELRSF KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQVNKSLLKIINDYEE FSRERTRSLEGSPEEGSNGEELCGLMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIIN NYDFTKAREKVPKLHSIRDRNGTHLDAGTVEPKREK NT seq 831 nt NT seq  +upstreamnt  +downstreamnt atggacttcaacagaaatctttatgatattggggaacaactggacagtgaagagctggcc tccctcaagttcctgagcctggactgcatcccacaaaggaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtcc ttcctgaaggagctgctcttccgaattaatagactggatttgctcactacttacctaaac actagaaaggaggagatggaaagggaacttcaggcaccaggcagggctcagatttctgcc tacagggtcatgctctatcagatttcagaagaggtgggcagatcagaattgaggtctttt aagtttcttctgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctg gatattttcatagagatggagaagagggtcatcctgggagaaggcaagttggacatcctg aagagagtctgtgcccaagtcaacaagagcctgctgaagataatcaatgactatgaagaa ttcagcagagagagaacaaggagccttgaaggaagtcctgaggaaggttcaaatggggag gagttgtgtgggctaatgacaatctcggactctccaagagaacaggatagtgaatcacag actttggacaaagtttaccaaatgaaaagcaaacctcggggatactgtctgatcatcaac aattacgattttacgaaagcacgggagaaagtgcccaaacttcacagcattagggacagg aatggaacacacttggatgcaggtacagtagaacccaaaagagaaaagtga

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